Activation of β-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells

Journal of Neurochemistry

Volumn 106, Issue 4, 2008, Pages 1855-1865

  Lim, Joseph C ^a   Kania, Katarzyna D ^a,b   Wijesuriya, Hasini ^a   Chawla, Sangeeta ^a   Sethi, Jaswinder K ^a   Pulaski, Lukasz ^b   Romero, Ignacio A ^c   Couraud, Pierre O ^d,e   Weksler, Babette B ^f   Hladky, Stephen B ^a   Barrand, Margery A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b INSTITUTE OF MEDICAL BIOLOGY   (Poland)

^c OPEN UNIVERSITY   (United Kingdom)

^d INSTITUT COCHIN   (France)

^e INSERM   (France)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

catenin; Brain endothelial cells; Breast cancer resistant protein; Glycogen synthase kinase 3; Multidrug resistance protein 4; P glycoprotein

Indexed keywords

1 AZAKENPAULLONE; 6 BROMOINDIRUBIN 3' OXIME; [2 AMINO 4 (3,4 (METHYLENEDIOXY) BENZYLAMINO) 6 (3 METHOXYPHENYL)PYRIMIDINE]; BETA CATENIN; BREAST CANCER RESISTANCE PROTEIN; CALCEIN; GLYCOGEN SYNTHASE KINASE 3; GLYCOPROTEIN P; LITHIUM CHLORIDE; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 4; QUERCETIN; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN BLOOD VESSEL; BRAIN CELL; CELL IMMORTALIZATION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INTERVENTION STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REGULATORY MECHANISM; WESTERN BLOTTING;

ANIMALS; BETA CATENIN; BLOOD-BRAIN BARRIER; BRAIN; CELL LINE, TRANSFORMED; CELLS, CULTURED; DOWN-REGULATION; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION; GLYCOGEN SYNTHASE KINASE 3; HUMANS; INDOLES; MALE; OXIMES; P-GLYCOPROTEIN; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; UP-REGULATION;

RATTUS;

EID: 48949084510     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05537.x     Document Type: Article

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