-
3
-
-
6944230093
-
Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging
-
DOI 10.1093/jnci/djh275
-
O'Connell JB, Maggard MA, Ko C Y. Colon cancer survival rates with the new american joint committee on cancer sixth edition staging. J Natl Cancer Inst 2004; 96:1420-1425 . (Pubitemid 39429665)
-
(2004)
Journal of the National Cancer Institute
, vol.96
, Issue.19
, pp. 1420-1425
-
-
O'Connell, J.B.1
Maggard, M.A.2
Ko, C.Y.3
-
4
-
-
15544381570
-
Self-renewal and cancer of the gut: Two sides of a coin
-
DOI 10.1126/science.1104815
-
Radtke F, Clevers H. Self-renewal and cancer of the gut: two sides of a coin. Science 2005; 307:1904-1909. (Pubitemid 40404692)
-
(2005)
Science
, vol.307
, Issue.5717
, pp. 1904-1909
-
-
Radtke, F.1
Clevers, H.2
-
5
-
-
0031877446
-
APC in the regulation of intestinal crypt fission
-
DOI 10.1002/(SICI)1096-9896(199807)185:3<246::AID-PATH90>3.0.CO;2-8
-
Wasan HS, Park HS, Liu KC et al. APC in the regulation of intestinal crypt fission.J Pathol 1998; 185:246-255. (Pubitemid 28320045)
-
(1998)
Journal of Pathology
, vol.185
, Issue.3
, pp. 246-255
-
-
Wasan, H.S.1
Park, H.-S.2
Liu, K.C.3
Mandir, N.K.4
Winnett, A.5
Sasieni, P.6
Bodmer, W.F.7
Goodlad, R.A.8
Wright, N.A.9
-
6
-
-
31444433936
-
Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission
-
DOI 10.1073/pnas.0505903103
-
Greaves LC, Preston SL, Tadrous PJ et al. Mitochondrial DNA mutations are established in human colonic stem cells and mutated clones expand by crypt fission. Proc Natl Acad Sci USA 2006 ; 103:714-719. (Pubitemid 43153091)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.3
, pp. 714-719
-
-
Greaves, L.C.1
Preston, S.L.2
Tadrous, P.J.3
Taylor, R.W.4
Barron, M.J.5
Oukrif, D.6
Leedham, S.J.7
Deheragoda, M.8
Sasieni, P.9
Novelli, M.R.10
Jankowski, J.A.Z.11
Turnbull, D.M.12
Wright, N.A.13
McDonald, S.A.C.14
-
7
-
-
0022001046
-
Derivation of mouse intestinal crypts from single progenitor cells
-
DOI 10.1038/313689a0
-
Ponder BAJ, Schmidt GH, Wilkinson MM et al. Derivation of mouse intestinal crypts from single progenitor cells. Nature 1985; 313:689-691. (Pubitemid 15172476)
-
(1985)
Nature
, vol.313
, Issue.6004
, pp. 689-691
-
-
Ponder, B.A.J.1
Schmidt, G.H.2
Wilkinson, M.M.3
-
8
-
-
0037068376
-
Methylation reveals a niche: Stem cell succession in human colon crypts
-
DOI 10.1038/sj.onc.1205604
-
Kim KM, Shibata D. Methylation reveals a niche: stem cell succession in human colon crypts. Oncogene 2002 ; 21:5441-5449. (Pubitemid 34983480)
-
(2002)
Oncogene
, vol.21
, Issue.35 REV. ISS. 3
, pp. 5441-5449
-
-
Kim, K.-M.1
Shibata, D.2
-
11
-
-
0016325705
-
Origin differentiation and renewal of the four maln epithelial cell rypes in the mouse small intestine. V. Unitarian theory of the origin of the four epithelial cell types
-
Cheng H, Leblond CPOrigin , differentiation and renewal of the four maln epithelial cell rypes in the mouse small intestine. V. Unitarian theory of the origin of the four epithelial cell types. Am J Anat 1974; 141:537-562.
-
(1974)
Am J Anat
, Issue.141
, pp. 537-562
-
-
Cheng, H.1
Leblond, C.P.2
-
12
-
-
0030882522
-
Epithelial cell growth and differentiation. 11. Intestinal apoptosis
-
PoccenCS. Epithelial cell growth and differentiation. 11. Intestinal apoptosis. Am J Physiol Gasrrointesr Liver Physiol 1997; 273:G253-G257.
-
(1997)
Am J Physiol Gasrrointesr Liver Physiol
, Issue.273
-
-
Poccen, C.S.1
-
13
-
-
33646045010
-
Stem sells and cancer: Two faces of Eve
-
Clarke MF, Fuller M. Stem sells and cancer: Two faces of Eve. Cell 2006; 124:1111-1115.
-
(2006)
Cell
, vol.124
, pp. 1111-1115
-
-
Clarke, M.F.1
Fuller, M.2
-
14
-
-
0014035736
-
The effect of plethora on growth and differentiation of normal hemopoietic colony-forming cells transplanted in mice of genotype W/Wv
-
Till JE, Siminovitch L, McCulloch EA. The effect of plethora on growth and differentiation of normal hemopoietic colony-forming cells transplanted in mice of genotype W/Wv. Blood 1967; 29:102-113.
-
(1967)
Blood
, vol.29
, pp. 102-113
-
-
Till, J.E.1
Siminovitch, L.2
McCulloch, E.A.3
-
15
-
-
0035499267
-
Stem cells cancer and cancerstem cells
-
Reya T, Morrison SJ, Clarke MF et al. Stem cells, cancer and cancerstem cells. Nature 2001 ; 414 :105-111.
-
(2001)
Nature
, vol.414
, pp. 105-111
-
-
Reya, T.1
Morrison, S.J.2
Clarke, M.F.3
-
16
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
DOI 10.1038/nm0797-730
-
Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997; 3:730-737. (Pubitemid 27298715)
-
(1997)
Nature Medicine
, vol.3
, Issue.7
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
17
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
DOI 10.1073/pnas.0530291100
-
Al Hajj M, Wicha MS, Benito-Hernandez A et al. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003; 100:3983-3988. (Pubitemid 36418143)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
18
-
-
1542283717
-
Characterization of clonogenic multiple myeloma cells
-
DOI 10.1182/blood-2003-09-3064
-
Matsui W, Huff CA, Wang Q et al. Characterization of clonogenic multiple myeloma cells. Blood 2004; 103:2332-2336. (Pubitemid 38326254)
-
(2004)
Blood
, vol.103
, Issue.6
, pp. 2332-2336
-
-
Matsui, W.1
Huff, C.A.2
Wang, Q.3
Malehorn, M.T.4
Barber, J.5
Tanhehco, Y.6
Smith, B.D.7
Civin, C.I.8
Jones, R.J.9
-
19
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh SK, Clarke ID, Terasaki M et al. Identification of a cancerstem cell in human braln tumors. Cancer Res 2003; 63:5821-5828. (Pubitemid 37187480)
-
(2003)
Cancer Research
, vol.63
, Issue.18
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
Bonn, V.E.4
Hawkins, C.5
Squire, J.6
Dirks, P.B.7
-
20
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
DOI 10.1158/0008-5472.CAN-05-2018
-
Collins AT, Berry PA, Hyde C et al. Prospective identification of tumorigenic prostate cancerstem cells. Cancer Res 2005; 65:10946-10951. (Pubitemid 41713363)
-
(2005)
Cancer Research
, vol.65
, Issue.23
, pp. 10946-10951
-
-
Collins, A.T.1
Berry, P.A.2
Hyde, C.3
Stower, M.J.4
Maitland, N.J.5
-
21
-
-
33846100356
-
A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
-
DOI 10.1038/nature05372, PII NATURE05372
-
O'Brien CA, Pollett A, Gallinger S et al. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007; 445:106-110. (Pubitemid 46067310)
-
(2007)
Nature
, vol.445
, Issue.7123
, pp. 106-110
-
-
O'Brien, C.A.1
Pollett, A.2
Gallinger, S.3
Dick, J.E.4
-
22
-
-
33846426141
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E et al. Identification and expansion of human colon- cancer-initiating cells. Nature 2006.
-
(2006)
Nature
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
-
23
-
-
33644826473
-
Roots and stems: Stem cells in cancer
-
DOI 10.1038/nm1379, PII N1379
-
Polyak K, Hahn WC. Roots and stems: stem cells in cancer. Nat Med 2006; 12:296-300. (Pubitemid 43355075)
-
(2006)
Nature Medicine
, vol.12
, Issue.3
, pp. 296-300
-
-
Polyak, K.1
Hahn, W.C.2
-
24
-
-
0035956913
-
Top-down morphogenesis of colorectal tumors
-
DOI 10.1073/pnas.051629398
-
Shih IM, Wang TL, Traverso G et al. Top-down morphogenesis of colorectal tumors. Proc Natl Acad Sci USA 2001 ; 98:2640-2645. (Pubitemid 32209535)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.5
, pp. 2640-2645
-
-
Shih, I.-M.1
Wang, T.-L.2
Traverso, G.3
Romans, K.4
Hamilton, S.R.5
Ben-Sasson, S.6
Kinzler, K.W.7
Vogelstein, B.8
-
26
-
-
0018357711
-
Staging of cancer of the colon and cancer of the rectum
-
DOI 10.1002/1097-0142(197903)43:3<961::AID-CNCR2820430327>3.0.CO;2- W
-
Wood DA, Robbins GF, Zippin C et al. Staging of cancer of the colon and cancer of the rectum. Cancer 1979; 43:961-968. (Pubitemid 9163627)
-
(1979)
Cancer
, vol.43
, Issue.3
, pp. 961-968
-
-
Wood, D.A.1
Robbins, G.F.2
Zippin, C.3
-
27
-
-
0346217047
-
The process for continuous improvement of the TNM classification
-
DOI 10.1002/cncr.11898
-
Gospodarowicz MK, Miller D, Groome PA et al. The process for continuous improvement of the TNM classification. Cancer 2004; 100:1-5. (Pubitemid 37553532)
-
(2004)
Cancer
, vol.100
, Issue.1
, pp. 1-5
-
-
Gospodarowicz, M.K.1
Miller, D.2
Groome, P.A.3
Greene, F.L.4
Logan, P.A.5
Sobin, L.H.6
-
28
-
-
0037244257
-
Colon polyps and cancer
-
DOI 10.1055/s-2003-36410
-
Bond JH. Colon Polyps and Cancer. Endoscopy 2003; 27-35. (Pubitemid 36131247)
-
(2003)
Endoscopy
, vol.35
, Issue.1
, pp. 27-35
-
-
Bond, J.H.1
-
29
-
-
0042941629
-
BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas
-
Chan TL , Zhao W, Cancer GP et al. BRAF and KRAS mutations in colorectal hyperplastic polyps and serrated adenomas. Cancer Res 2003; 63:4878-4881. (Pubitemid 37022620)
-
(2003)
Cancer Research
, vol.63
, Issue.16
, pp. 4878-4881
-
-
Chan, T.L.1
Zhao, W.2
Leung, S.Y.3
Yuen, S.T.4
-
30
-
-
0001126259
-
A genetic and clinical study of intestinal polyposis a predisposing factor for carcinoma of the colon and rectum
-
Gardner EJ. A genetic and clinical study of intestinal polyposis, a predisposing factor for carcinoma of the colon and rectum. Am J Hum Genet 1951; 3:167-176.
-
(1951)
Am J Hum Genet
, vol.3
, pp. 167-176
-
-
Gardner, E.J.1
-
31
-
-
0030917708
-
Studies of neoplasia in the Min mouse
-
DOI 10.1016/S0304-419X(96)00041-8, PII S0304419X96000418
-
Shoemaker AR, Gould KA, Luongo C et al. Studies of neoplasia in the Min mouse. Biochim Biophys Acta 1997; 1332:F25-F48. (Pubitemid 27211615)
-
(1997)
Biochimica et Biophysica Acta - Reviews on Cancer
, vol.1332
, Issue.2
-
-
Shoemaker, A.R.1
Gould, K.A.2
Luongo, C.3
Moser, A.R.4
Dove, W.F.5
-
32
-
-
0022810104
-
Brief clinical report: Gardner syndrome in a man with an interstitial deletion of 5q
-
Herrera L, Kakati S, Gibas L et al. Brief clinical report : gardner syndrome in a man with an interstitial deletion of 5q. Am J Hum Genet 1986; 25:473-476. (Pubitemid 16008369)
-
(1986)
American Journal of Medical Genetics
, vol.25
, Issue.3
, pp. 473-476
-
-
Herrera, L.1
Kakati, S.2
Gibas, L.3
-
33
-
-
0023223410
-
Localization of the gene for familial adenomatous polyposis on chromosome 5
-
DOI 10.1038/328614a0
-
Bodmer WF. Balley CJ, Bodmer J et al. Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature 1987; 328:614-616. (Pubitemid 17103960)
-
(1987)
Nature
, vol.328
, Issue.6131
, pp. 614-616
-
-
Bodmer, W.F.1
Bailey, C.J.2
Bodmer, J.3
-
34
-
-
0025817880
-
Identification of FAP locus genes from chromosome 5q21
-
Kinzler KW, Nilbert MC, Su LK et al. Identification of FAP locus genes from chromosome 5q21. Science 1991; 253:661-665. (Pubitemid 21917199)
-
(1991)
Science
, vol.253
, Issue.5020
, pp. 661-665
-
-
Kinzler, K.W.1
Nilbert, M.C.2
Su, L.-K.3
Vogelstein, B.4
Bryan, T.M.5
Levy, D.B.6
Smith, K.J.7
Preisinger, A.C.8
Hedge, P.9
Mckechnie, D.10
Finniear, R.11
Markham, A.12
Groffen, J.13
Boguski, M.S.14
Altschul, S.F.15
Horii, A.16
Ando, H.17
Miyoshi, Y.18
Miki, Y.19
Nishisho, I.20
Nakamura, Y.21
more..
-
35
-
-
0025899162
-
Mutation of chromosome 5q21 genes in FAP and colorectal cancer patients
-
Nishisho I, Nakamura Y, Miyoshi Yet al. Mutat ion of chromosome 5q21 genes in FAP and colorectal cancer patients. Science 1991; 253:665-668.
-
(1991)
Science
, vol.253
, pp. 665-668
-
-
Nishisho, I.1
Nakamura, Y.2
Miyoshi, Y.3
-
36
-
-
0025941471
-
Identification of deletion mutations and three new genes at the familial polyposis locus
-
Joslyn G, Carlson M. Thliveris A et al. Identification of deletion mutations and three new genes at the familial polyposis locus. Cell 1991; 66:601-613.
-
(1991)
Cell
, Issue.66
, pp. 601-613
-
-
Joslyn, G.1
Carlson, M.2
Thliveris, A.3
-
37
-
-
0025938038
-
Identification and characterization of the familial adenomatous polyposis coli gene
-
Groden J. Thliveris A, Samowitz W et al. Identification and characterization of the familial adenomatous polyposis coli gene. Cell 1991; 66:589-600.
-
(1991)
Cell
, vol.66
, pp. 589-600
-
-
Groden, J.1
Thliveris, A.2
Samowitz, W.3
-
39
-
-
0026470030
-
Frequent somatic mutations of the APC gene in human pancreatic cancer
-
Horii A, Nakarsuru S. Miyoshi Yet al. Frequent somatic mutations of the APC gene in human pancreatic cancer. Cancer Res 1992; 52:6696-6698.
-
(1992)
Cancer Res
, vol.52
, pp. 6696-6698
-
-
Horii, A.1
Nakarsuru, S.2
Miyoshi, Y.3
-
40
-
-
4944260954
-
Monoallelic methylation of the APC promoter is altered in normal gastric mucosa associated with neoplastic lesions
-
DOI 10.1158/0008-5472.CAN-03-2503
-
Clement G, Bosman FT, Fonrollict C et al. Monoallelic methylation of the APC promoter is altered in normal gastric mucosa associated with neoplastic lesions. Cancer Res 2004; 64:6867-6873. (Pubitemid 39330993)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 6867-6873
-
-
Clement, G.1
Bosman, F.T.2
Fontolliet, C.3
Benhattar, J.4
-
41
-
-
0027756014
-
Association of the APC tumor suppressor protein with catenins
-
Su LK, Vogelstein B, Kinzler KW. Association of the APC tumor suppressor prote in with catenins, Science 1993; 262:1734-1737. (Pubitemid 24030097)
-
(1993)
Science
, vol.262
, Issue.5140
, pp. 1734-1737
-
-
Su, L.-K.1
Vogelstein, B.2
Kinzler, K.W.3
-
42
-
-
0027738023
-
Association of the APC gene product with β-catenin
-
Rubinfeld B. Souza B, Albert I et al. Association of the APC gene product with 13-catenin. Science 1993; 262:1731-1734. (Pubitemid 24030096)
-
(1993)
Science
, vol.262
, Issue.5140
, pp. 1731-1734
-
-
Rubinfeld, B.1
Souza, B.2
Albert, I.3
Muller, O.4
Chamberlain, S.H.5
Masiarz, F.R.6
Munemitsu, S.7
Polakis, P.8
-
43
-
-
0036033274
-
Genetics of colorectal cancer: Hereditary aspects and overview of colorectal tumorigenesis
-
DOI 10.1093/bmb/64.1.27
-
Fearnhead NS, WildingJL, Bodmer WF. Genetics of colorectal cancer: heredit ary aspects and overview of colorectal tumorigenesis. Br Med Bull 2002; 64:27-43. (Pubitemid 35238577)
-
(2002)
British Medical Bulletin
, vol.64
, pp. 27-43
-
-
Fearnhead, N.S.1
Wilding, J.L.2
Bodmer, W.F.3
-
44
-
-
33745225167
-
CRD-BP mediates stabilization of [betaJTrCPl and c-myc mRNA in response to [beta]-catenin signalling
-
Noubissi FK, Elcheva I, Bhatia N et al. CRD-BP mediates stabilization of [beta]TrCPl and c-myc mRNA in response to [beta]-catenin signalling. Nature 2006; 441:898-901.
-
(2006)
Nature
, vol.441
, pp. 898-901
-
-
Noubissi, F.K.1
Elcheva, I.2
Bhatia, N.3
-
45
-
-
0033230616
-
Intestinal polyposis in mice with a dominant stable mutation of the β-catenin gene
-
DOI 10.1093/emboj/18.21.5931
-
Harada N, Tarnal Y, Ishikawa T et al. Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene. EMBO J 1999; 18:5931-5942. (Pubitemid 29515670)
-
(1999)
EMBO Journal
, vol.18
, Issue.21
, pp. 5931-5942
-
-
Harada, N.1
Tamai, Y.2
Ishikawa, T.-O.3
Sauer, B.4
Takaku, K.5
Oshima, M.6
Taketo, M.M.7
-
46
-
-
0033566821
-
Intestinal dysplasia and adenoma in transgenic mice after overexpression of an activated β-catenin
-
Romagnolo B, Berrebi D. Saadi-Keddoucci S et al. Intestinal dysplasia and adenoma in transgenic mice after overexpression of an activated 13-catenin. Cancer Res 1999; 59:3875-3879. (Pubitemid 29393543)
-
(1999)
Cancer Research
, vol.59
, Issue.16
, pp. 3875-3879
-
-
Romagnolo, B.1
Berrebi, D.2
Saadi-Keddoucci, S.3
Porteu, A.4
Pichard, A.-L.5
Peuchmaur, M.6
Vandewalle, A.7
Kahn, A.8
Perret, C.9
-
47
-
-
0028229809
-
Demonstration of promoter activity and alternative splicing in the region 5' to exon 1 of the APC gene
-
Thliveris A, Samowitz W; Matsunami N et al. Demonstration of promoter activity and alternative splicing in the region 5' to exon 1 of the APC gene. Cancer Res 1994; 54:2991-2995.
-
(1994)
Cancer Res
, vol.54
, pp. 2991-2995
-
-
Thliveris, A.1
Samowitz, W.2
Matsunami, N.3
-
48
-
-
0030766495
-
Novel exon connections of the brain-specific (BS) exon of the adenomatous polyposis coli gene
-
DOI 10.1002/(SICI)1097-0215(19970926)73:1<137::AID-IJC21>3.0.CO;2-C
-
Bardos J, Sulekova Z, Ballhausen WG. Novel exon connections of the braln-specific (BS) exon of the adenomatous polyposis coli gene. Int J Cancer 1997; 73:137-142. (Pubitemid 27446001)
-
(1997)
International Journal of Cancer
, vol.73
, Issue.1
, pp. 137-142
-
-
Bardos, J.1
Sulekova, Z.2
Ballhausen, W.G.3
-
49
-
-
0032495571
-
Novel protein isoforms of the APC tumor suppressor in neural tissue
-
Pyles RB, Santoro IM, Groden J et al. Novel protein isoforms of the APC tumor suppressor in neural tissue. Oncogene 1998; 16:77-82. (Pubitemid 28043510)
-
(1998)
Oncogene
, vol.16
, Issue.1
, pp. 77-82
-
-
Pyles, R.B.1
Santoro, I.M.2
Groden, J.3
Parysek, L.M.4
-
50
-
-
0029664368
-
Binding of GSK3β to the APC-β-catenin complex and regulation of complex assembly
-
Rubinfeld B, Albert I, Porfiri E et al. Binding of GSK3β to the APC -13-catenin complex and regulation of complex assembly. Science 1996; 272:1023-1026. (Pubitemid 26259322)
-
(1996)
Science
, vol.272
, Issue.5264
, pp. 1023-1026
-
-
Rubinfeld, B.1
Albert, I.2
Porfiri, E.3
Fiol, C.4
Munemitsu, S.5
Polakis, P.6
-
51
-
-
0032562603
-
Functional interaction of an axin homolog, conducrin, with 13-catenin, APC and GSK3β
-
Behrens J, Jerchow BA, Wurtele M et al. Functional interaction of an axin homolog, conducrin, with 13-catenin, APC and GSK3β. Science 1998; 280:596-599.
-
(1998)
Science
, vol.280
, pp. 596-599
-
-
Behrens, J.1
Jerchow, B.A.2
Wurtele, M.3
-
52
-
-
0035176077
-
Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3β phosphorylation
-
DOI 10.1016/S0960-9822(01)00002-1
-
Zumbrunn J, Kinoshita K, Hyman AA et al. Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3[beta] phosphorylation. Curr Biol 2001; 11:44-49. (Pubitemid 32062715)
-
(2001)
Current Biology
, vol.11
, Issue.1
, pp. 44-49
-
-
Zumbrunn, J.1
Kinoshita, K.2
Hyman, A.A.3
Nathke, I.S.4
-
53
-
-
0031557898
-
The adenomatous polyposis coli (APC) tumor suppressot
-
Polakis P. The adenomatous polyposis coli (APC) tumor suppressot. Biochim Biophys Acta 1997; 1332:FI27-FI48.
-
(1997)
Biochim Biophys Acta
, vol.1332
-
-
Polakis, P.1
-
55
-
-
0036226855
-
Identification of a link between the tumour suppressor APC and the kinesin superfamily
-
DOI 10.1038/ncb779
-
Jimbo T. Kawasaki Y,Koyama R et al. Identification of a link between the tumour suppressor APC and the kinesin superfamily. Nat Cell Biol 2002; 4:323-327. (Pubitemid 34308860)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.4
, pp. 323-327
-
-
Jimbo, T.1
Kawasaki, Y.2
Koyama, R.3
Sato, R.4
Takada, S.5
Haraguchi, K.6
Akiyama, T.7
-
56
-
-
35648988947
-
Adenomatous polyposis coli (APC): A multi-functional tumor suppressor gene
-
DOI 10.1242/jcs.03485
-
Aoki K, Taketo MM. Adcnornatous polyposis coli (APC) : a multi-functional tumor suppressor gene. J Cell Sci 2007; 120:3327-3335. (Pubitemid 350028340)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.19
, pp. 3327-3335
-
-
Aoki, K.1
Taketo, M.M.2
-
57
-
-
0034724186
-
APC mutations in sporadic colorectal tumors: A mutational 'hotspot' and interdependence of the 'two hits'
-
DOI 10.1073/pnas.97.7.3352
-
Rowan AJ, Lamlum H, Ilyas M et al. APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits". Proc Natl Acad Sci USA 2000; 97:3352-3357. (Pubitemid 30183306)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.7
, pp. 3352-3357
-
-
Rowan, A.J.1
Lamlum, H.2
Ilyas, M.3
Wheeler, J.4
Straub, J.5
Papadopoulou, A.6
Bicknell, D.7
Bodmer, W.F.8
Tomlinson, I.P.M.9
-
58
-
-
0037096906
-
The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the β-catenin signaling cascade
-
Albuquerque C, Breukel C, van der LR et al. The 'just-right' signaling model: APC somatic mutations arc selected based on a specific level of activation of the beta-catenin signaling cascade. Hum Mol Genet 2002; 11:1549-1560. (Pubitemid 34679255)
-
(2002)
Human Molecular Genetics
, vol.11
, Issue.13
, pp. 1549-1560
-
-
Albuquerque, C.1
Breukel, C.2
Van Der Luijt, R.3
Fidalgo, P.4
Lage, P.5
Slors, F.J.M.6
Nobre Leitao, C.7
Fodde, R.8
Smits, R.9
-
59
-
-
0037699438
-
Refining the relation between 'first hits' and 'second hits' at the APC locus: The 'loose fit' model and evidence for differences in somatic mutation spectra among patients
-
DOI 10.1038/sj.onc.1206471
-
Crabtree M, Sieber OM, Lipton L et al. Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients. Oncogene 2003; 22:4257-4265. (Pubitemid 36876246)
-
(2003)
Oncogene
, vol.22
, Issue.27
, pp. 4257-4265
-
-
Crabtree, M.1
Sieber, O.M.2
Lipton, L.3
Hodgson, S.V.4
Lamlum, H.5
Thomas, H.J.W.6
Neale, K.7
Phillips, R.K.S.8
Heinimann, K.9
Tomlinson, I.P.M.10
-
60
-
-
0036719949
-
Explalning variation in familial adenomatous polyposis: Relationship between genotype and phenotype and evidence for modifier genes
-
Crabrree MD, Tomlinson IPM. Hodgson SV et al. Explalning variation in familial adenomatous polyposis: relationship between genotype and phenotype and evidence for modifier genes. Gut 2002; 51:420-423.
-
(2002)
Gut
, vol.51
, pp. 420-423
-
-
Crabrree, M.D.1
Tomlinson, I.P.M.2
Hodgson, S.V.3
-
61
-
-
17944369235
-
Contrasting molecular pathology of colorectal carcinoma in Egyptian and Western patients
-
DOI 10.1038/sj.bjc.6691838
-
Soliman AS. Bondy ML. El BadawySA et al. Contrasting molecular pathology of colorectal carcinoma in Egyptian and Western patients. Br J Cancer 2001: 85:1037-1046. (Pubitemid 33016007)
-
(2001)
British Journal of Cancer
, vol.85
, Issue.7
, pp. 1037-1046
-
-
Soliman, A.S.1
Bondy, M.L.2
El-Badawy, S.A.3
Mokhtar, N.4
Eissa, S.5
Bayoumy, S.6
Seifeldin, I.A.7
Houlihan, P.S.8
Lukish, J.R.9
Watanabe, T.10
Chan, A.O.O.11
Zhu, D.12
Amos, C.I.13
Levin, B.14
Hamilton, S.R.15
-
62
-
-
0025015168
-
A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse
-
Moser AR. Pitot HC. Dove WE A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse. Science 1990: 247:322-324.
-
(1990)
Science
, vol.247
, pp. 322-324
-
-
Moser, A.R.1
Pitot, H.C.2
Dove, W.E.3
-
63
-
-
0026562404
-
Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene
-
Su LK. Kinzler KW;VogelsteinB et al. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene. Science 1992; 256:668-670.
-
(1992)
Science
, vol.256
, pp. 668-670
-
-
Su, L.K.1
Kinzler, K.W.2
Vogelstein, B.3
-
64
-
-
0034020480
-
Suppression of polypogenesis in a new mouse strain with a truncated ApC(δ474) by a novel COX-2 inhibitor, JTE-522
-
Sasal H, Masaki M. Wakitani K. Suppression of polypogenesis in a new mouse straln with a truncated Apc{Delta}474 by a novel COX-2 inhibitor. JTE-522. Carcinogenesis 2000: 21:953-958. (Pubitemid 30265139)
-
(2000)
Carcinogenesis
, vol.21
, Issue.5
, pp. 953-958
-
-
Sasai, H.1
Masaki, M.2
Wakitani, K.3
-
65
-
-
10044221016
-
Colorectal cancers in a new mouse model of familial adenomatous polyposis: Influence of genetic and environmental modifiers
-
DOI 10.1038/labinvest.3700180
-
Colnot S, Niwa-Kawakita M, Hamard G et al. Coloreccal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers. Lab Invest 2004; 84:1619-1630. (Pubitemid 39600569)
-
(2004)
Laboratory Investigation
, vol.84
, Issue.12
, pp. 1619-1630
-
-
Colnot, S.1
Niwa-Kawakita, M.2
Hamard, G.3
Godard, C.4
Le Plenier, S.5
Houbron, C.6
Romagnolo, B.7
Berrebi, D.8
Giovannini, M.9
Perret, C.10
-
66
-
-
0029047954
-
Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene
-
Oshima M. Oshima H, Kicagawa K et al. Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene. Proc Nad Acad Sci USA 1995: 92:4482-4486.
-
(1995)
Proc Nad Acad Sci USA
, vol.92
, pp. 4482-4486
-
-
Oshima, M.1
Oshima, H.2
Kicagawa, K.3
-
67
-
-
0037440378
-
Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo
-
DOI 10.1016/S0012-1606(02)00020-9, PII S0012160602000209
-
Ishikawa T. Tarnal Y, Li Qet al. Requirement for rumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo. Dev Biol 2003: 253:230-246. (Pubitemid 36259884)
-
(2003)
Developmental Biology
, vol.253
, Issue.2
, pp. 230-246
-
-
Ishikawa, T.-O.1
Tamai, Y.2
Li, Q.3
Oshima, M.4
Taketo, M.M.5
-
68
-
-
0141842617
-
Concomitant suppression of hyperlipidemia and intestinal polyp formation in Apc-deficient mice by peroxisome proliferator-activated receptor ligands
-
Niho N. Takahashi M, Kitamura T et al. Concomitanr suppression of hyperlipidemia and intestinal polyp formation in APC-deficient mice by peroxisome proliferaror-activared receptor ligands. Cancer Res 2003 : 63:6090-6095. (Pubitemid 37187515)
-
(2003)
Cancer Research
, vol.63
, Issue.18
, pp. 6090-6095
-
-
Niho, N.1
Takahashi, M.2
Kitamura, T.3
Shoji, Y.4
Itoh, M.5
Noda, T.6
Sugimura, T.7
Wakabayashi, K.8
-
69
-
-
0028567875
-
A targeted chaln-termination mutation in the mouse Apc gene results in multiple intestinal tumors
-
Fodde R. Edelmann W; Yang K et al. A targeted chaln-termination mutation in the mouse Apc gene results in multiple intestinal tumors. Proc Natl Acad Sci USA 1994; 91:8969-8973.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8969-8973
-
-
Fodde, R.1
Edelmann, W.2
Yang, K.3
-
70
-
-
0033563226
-
Apc1638T: A mouse model delineating critical domains of the adenomatous polyposis coli protein involved in tumorigenesis and development
-
Smits R, Kielman MF, Breukel C et al. Apc1638T: a mouse model delineating critical domalns of the adenomacous polyposis coli protein involved in tumorigenesis and development. Genes Dev 1999; 13:1309-1321. (Pubitemid 29250198)
-
(1999)
Genes and Development
, vol.13
, Issue.10
, pp. 1309-1321
-
-
Smits, R.1
Kielman, M.F.2
Breukel, C.3
Zurcher, C.4
Neufeld, K.5
Jagmohan-Changur, S.6
Hofland, N.7
Van Dijk, J.8
White, R.9
Edelmann, W.10
Kucherlapati, R.11
Meera Khan, P.12
Fodde, R.13
-
71
-
-
25444497707
-
The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis
-
DOI 10.1158/0008-5472.CAN-05-2145
-
Li Q, Ishikawa TO, Oshima M et al. The threshold level of adenomacous polyposis coli protein for mouse intestinal tumorigenesis. Cancer Res 2005: 65:8622-8627. (Pubitemid 41377347)
-
(2005)
Cancer Research
, vol.65
, Issue.19
, pp. 8622-8627
-
-
Li, Q.1
Ishikawa, T.-O.2
Oshima, M.3
Taketo, M.M.4
-
73
-
-
34248218101
-
The modifier of Min 2 (Mom2) locus: Embryonic lethality of a mutation in the Atp5a1 gene suggests a novel mechanism of polyp suppression
-
DOI 10.1101/gr.6089707
-
Baran AA. Silverman KA, Zeskand Jet al. The modifier of Min 2 (Mom2) locus: embryonic lethality of a mutation in the Atp5al gene suggests a novel mechanism of polyp suppression. Genome Res 2007; 17:566-576. (Pubitemid 46715506)
-
(2007)
Genome Research
, vol.17
, Issue.5
, pp. 566-576
-
-
Baran, A.A.1
Silverman, K.A.2
Zeskand, J.3
Koratkar, R.4
Palmer, A.5
McCullen, K.6
Curran Jr., W.J.7
Edmonston, T.B.8
Siracusa, L.D.9
Buchberg, A.M.10
-
74
-
-
23944472219
-
Loss of adenomatous polyposis coli gene function disrupts thymic development
-
DOI 10.1038/ni1228, PII N1228
-
Gounari F, Chang R. Cowan J et al. Loss of adenomatous polyposis coli gene function disrupts thymic development. Nat lmmunol 2005; 6:800-809. (Pubitemid 43090466)
-
(2005)
Nature Immunology
, vol.6
, Issue.8
, pp. 800-809
-
-
Gounari, F.1
Chang, R.2
Cowan, J.3
Guo, Z.4
Dose, M.5
Gounaris, E.6
Khazaie, K.7
-
75
-
-
0030843461
-
Rapid colorecral adenoma formation initiated by conditional cargeting of the Apc gene
-
Shibata H, Toyama K. Shioya H et al. Rapid colorecral adenoma formation initiated by conditional cargeting of the Apc gene. Science 1997; 278:120-123.
-
(1997)
Science
, vol.278
, pp. 120-123
-
-
Shibata, H.1
Toyama, K.2
Shioya, H.3
-
76
-
-
10344254872
-
Liver-targeted disruption of Apc in mice activates β-catenin signaling and leads to hepatocellular carcinomas
-
DOI 10.1073/pnas.0404761101
-
Colnot S. Decaens T. Niwa-Kawakita M et al. Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomas. Proc Natl Acad Sci USA 2004; 101:17216-17221. (Pubitemid 39627800)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.49
, pp. 17216-17221
-
-
Colnot, S.1
Decaens, T.2
Niwa-Kawakita, M.3
Godard, C.4
Hamard, G.5
Kahn, A.6
Giovannini, M.7
Perret, C.8
-
78
-
-
2942668475
-
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
-
DOI 10.1101/gad.287404
-
Sansom OJ. Reed KR. Hayes AJ et al. Loss of Apc in vivo immediately perturbs Wnt signaling differentiation and migration. Genes Dev 2004; 18:1385-1390. (Pubitemid 38780625)
-
(2004)
Genes and Development
, vol.18
, Issue.12
, pp. 1385-1390
-
-
Sansom, O.J.1
Reed, K.R.2
Hayes, A.J.3
Ireland, H.4
Brinkmann, H.5
Newton, I.P.6
Batlle, E.7
Simon-Assmann, P.8
Clevers, H.9
Nathke, I.S.10
Clarke, A.R.11
Winton, D.J.12
-
79
-
-
20244387973
-
Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine
-
DOI 10.1242/dev.01700
-
Andreu P. Colnor S. Godard C et al. Crypt-restricted proliferation and commitment to the Paneth cell lineage following APC loss in the mouse intestine. Development 2005; 132:1443-1451. (Pubitemid 40528801)
-
(2005)
Development
, vol.132
, Issue.6
, pp. 1443-1451
-
-
Andreu, P.1
Colnot, S.2
Godard, C.3
Gad, S.4
Chafey, P.5
Niwa-Kawakita, M.6
Laurent-Puig, P.7
Kahn, A.8
Robine, S.9
Perret, C.10
Romagnolo, B.11
-
80
-
-
34247187543
-
Myc deletion rescues Apc deficiency in the small intestine
-
DOI 10.1038/nature05674, PII NATURE05674
-
Sansom OJ. Mcniel VS. Muncan V et al, Myc deletion rescues Apc deficiency in the small intestine. Nature 2007: 446:676-679. (Pubitemid 46606884)
-
(2007)
Nature
, vol.446
, Issue.7136
, pp. 676-679
-
-
Sansom, O.J.1
Meniel, V.S.2
Muncan, V.3
Phesse, T.J.4
Wilkins, J.A.5
Reed, K.R.6
Vass, J.K.7
Athineos, D.8
Clevers, H.9
Clarke, A.R.10
-
81
-
-
27944437061
-
Azoxymethane is a genetic background-dependent colorectal tumor initiator and promoter in mice: Effects of dose, route, and diet
-
DOI 10.1093/toxsci/kfi313
-
Bissahoyo A, Pearsall RS. Hanlon K et al. Azoxymethane is a genetic background-dependent colorectal tumor initiaror and promoter in mice: effects of dose. route and diet. Toxicol Sci 2005; Dec;88(2) :340-5. Epub 2005 Sep 8. (Pubitemid 41672142)
-
(2005)
Toxicological Sciences
, vol.88
, Issue.2
, pp. 340-345
-
-
Bissahoyo, A.1
Pearsall, R.S.2
Hanlon, K.3
Amann, V.4
Hicks, D.5
Godfrey, V.L.6
Threadgill, D.W.7
-
82
-
-
0028981283
-
N-echyl-N-nicrosourea rreatmenr of multiple intestinal neoplasia (Min) mice: Age-related effects on the formation of intestinal adenomas, cystic crypcs and epidermoid cysts
-
Shoemaker AR. Moser AR. Dove WE N-echyl-N-nicrosourea rreatmenr of multiple intestinal neoplasia (Min) mice: age-related effects on the formation of intestinal adenomas, cystic crypcs and epidermoid cysts. Cancer Res 1995: 55:4479-4485.
-
(1995)
Cancer Res
, vol.55
, pp. 4479-4485
-
-
Shoemaker, A.R.1
Moser, A.R.2
Dove, W.E.3
-
83
-
-
3142664714
-
Transforming growth factor β receptor type II inactivation promotes the establishment and progression of colon cancer
-
DOI 10.1158/0008-5472.CAN-03-3255
-
Biswas S, Chytil A. Washington K et al. Transforming growth facror beta receptor type II inactivation promoces the establishment and progression of colon cancer. Cancer Res 2004: 64:4687-4692. (Pubitemid 38924506)
-
(2004)
Cancer Research
, vol.64
, Issue.14
, pp. 4687-4692
-
-
Biswas, S.1
Chytil, A.2
Washington, K.3
Romero-Gallo, J.4
Gorska, A.E.5
Wirth, P.S.6
Gautam, S.7
Moses, H.L.8
Grady, W.M.9
-
86
-
-
0038079684
-
Bottom-up histogenesis of colorectal adenomas: Origin in the monocryptal adenoma and initial expansion by crypt fission
-
Preston SL, Wong WM, Chan AO et al. Borrom-up histogenesis of colorectal adenomas: origin in the monocrypcal adenoma and initial expansion by crypt fission. Cancer Res 2003: 63:3819-3825. (Pubitemid 36793072)
-
(2003)
Cancer Research
, vol.63
, Issue.13
, pp. 3819-3825
-
-
Preston, S.L.1
Wong, W.-M.2
Chan, A.O.-O.3
Poulsom, R.4
Jeffery, R.5
Goodlad, R.A.6
Mandir, N.7
Elia, G.8
Novelli, M.9
Bodmer, W.F.10
Tomlinson, I.P.11
Wright, N.A.12
-
87
-
-
38849171845
-
Expansion of a mutated clone: From stem cell to tumour
-
DOI 10.1136/jcp.2006.044610
-
Leedham S, Wright N. Expansion of a mutated clone-from stem cell to tumour. J Clin Pathol 2008; Feb;61(2) :164-71. Epub 2007 Apr 27. (Pubitemid 351218875)
-
(2008)
Journal of Clinical Pathology
, vol.61
, Issue.2
, pp. 164-171
-
-
Leedham, S.J.1
Wright, N.A.2
-
88
-
-
0018972837
-
Neoplastic and nonneoplastic lesions in aging Osborne-Mendel rats
-
DOI 10.1016/0041-008X(80)90045-9
-
Goodman DG, Ward JM, Squire RA et al. Neoplastic and Nonneoplastic Lesions in Aging Osborne-Mendel Rats. Toxicology and Applied Pharmacology 1980; 55:433-447. (Pubitemid 10024677)
-
(1980)
Toxicology and Applied Pharmacology
, vol.55
, Issue.3
, pp. 433-447
-
-
Goodman, D.G.1
Ward, J.M.2
Squire, R.A.3
-
89
-
-
0016626074
-
Colon carcinoma of highly inbred rats
-
Miyamoto M, Takizawa S. Colon carcinoma of highly inbred rats. J Natl Cancer Inst 1975 ; 55:1471-1472
-
(1975)
J Natl Cancer Inst
, vol.55
, pp. 1471-1472
-
-
Miyamoto, M.1
Takizawa, S.2
-
90
-
-
27644468268
-
How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon Chemoprevencion in rats, mice and men
-
Corper DE, Pierre E How good are rodent models of carcinogenesis in predicting efficacy in humans? A systematic review and meta-analysis of colon Chemoprevencion in rats, mice and men. Eur J Cancer 2005 ; 41:1911-1922.
-
(2005)
Eur J Cancer
, vol.41
, pp. 1911-1922
-
-
Corper, D.E.1
Pierre, E.2
-
91
-
-
0037685273
-
Production of knockout rats using ENU mutagenesis and a yeast-based screening assay
-
DOI 10.1038/nbt830
-
Zan Y. Haag JD, Chen KS et al. Production of knockout rats using ENU mutagenesis and a yeast-based screening assay. Nat Biotechnol 2003; 21:645-651. (Pubitemid 36638091)
-
(2003)
Nature Biotechnology
, vol.21
, Issue.6
, pp. 645-651
-
-
Zan, Y.1
Haag, J.D.2
Chen, K.-S.3
Shepel, L.A.4
Wigington, D.5
Wang, Y.-R.6
Hu, R.7
Lopez-Guajardo, C.C.8
Brosel, H.L.9
Porter, K.I.10
Leonard, R.A.11
Hitt, A.A.12
Schommer, S.L.13
Elegbede, A.F.14
Gould, M.N.15
-
92
-
-
33644601589
-
Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis
-
Smits BM. Mudde JB, van de BJ et al. Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis. Pharmacogenet Genomics 2006; 16:159-169.
-
(2006)
Pharmacogenet Genomics
, vol.16
, pp. 159-169
-
-
Smits, B.M.1
Mudde, J.B.2
Van De, B.J.3
-
93
-
-
34247231997
-
A target-selected Apc-mutant rat kindred enhances the modeling of familial human colon cancer
-
DOI 10.1073/pnas.0611690104
-
Amos-Landgraf JM. KwongLN. Kendzierski CM et al.A target-selected APC-mutant rat kindred enhances the modeling of familial human colon cancer. Proc Natl Acad Sci USA 2007; 104:4036-4041. (Pubitemid 47181574)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.10
, pp. 4036-4041
-
-
Amos-Landgraf, J.M.1
Kwong, L.N.2
Kendziorski, C.M.3
Reichelderfer, M.4
Torrealba, J.5
Weichert, J.6
Haag, J.D.7
Chen, K.-S.8
Waller, J.L.9
Gould, M.N.10
Dove, W.F.11
-
94
-
-
33645508586
-
Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia
-
Haramis AP, Hurlstone A. Van D et al. Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia. EMBO Rep 2006; 7:444-449.
-
(2006)
EMBO Rep
, vol.7
, pp. 444-449
-
-
Haramis, A.P.1
Hurlstone, A.2
Van, D.3
-
95
-
-
33745919542
-
Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila
-
DOI 10.1242/dev.02398
-
McCartney BM. Price MH. Webb RL et al. Testing hypotheses for the functions of APC family proteins using null and truncation alleles in Drosophila. Development 2006; 133:2407-2418. (Pubitemid 44044561)
-
(2006)
Development
, vol.133
, Issue.12
, pp. 2407-2418
-
-
McCartney, B.M.1
Price, M.H.2
Webb, R.L.3
Hayden, M.A.4
Holot, L.M.5
Zhou, M.6
Bejsovec, A.7
Peifer, M.8
-
96
-
-
6544276454
-
Identification and characterization of E-APC, a novel Drosophila homologue of the tumour suppressor APC
-
DOI 10.1046/j.1365-2443.1999.00272.x
-
Hamada F. Murata Y.Nishida A et al. Identification and characterization of E-APC, a novel Drosophila homologue of the tumour suppressor APC. Genes to Cells 1999; 4:465-474. (Pubitemid 29507084)
-
(1999)
Genes to Cells
, vol.4
, Issue.8
, pp. 465-474
-
-
Hamada, F.1
Murata, Y.2
Nishida, A.3
Fujita, F.4
Tomoyasu, Y.5
Nakamura, M.6
Toyoshima, K.7
Tabata, T.8
Ueno, N.9
Akiyama, T.10
-
97
-
-
0030829387
-
Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos
-
DOI 10.1016/S0092-8674(00)80531-0
-
Rocheleau CE Downs WO. Lin R et al. Wnt Signaling and an APC -Related Gene Specify Endoderm in Early C. Elegans Embryos. Cell 1997; 90:707-716. (Pubitemid 27357962)
-
(1997)
Cell
, vol.90
, Issue.4
, pp. 707-716
-
-
Rocheleau, C.E.1
Downs, W.D.2
Lin, R.3
Wittmann, C.4
Bei, Y.5
Cha, Y.-H.6
Ali, M.7
Priess, J.R.8
Mello, C.C.9
-
98
-
-
33846580993
-
Cortical β-catenin and APC regulate asymmetric nuclear beta-catenin localization during asymmetric cell division in C. Elegans
-
DOI 10.1016/j.devcel.2007.01.004, PII S1534580707000056
-
Mizumoto K. Sawa H. Cortical β-catenin and APC regulate asymmetric nuclear beta-catenin localization during asymmetric cell division in C. Elegans, Dev Cell 2007; 12:287-299. (Pubitemid 46172907)
-
(2007)
Developmental Cell
, vol.12
, Issue.2
, pp. 287-299
-
-
Mizumoto, K.1
Sawa, H.2
-
100
-
-
0037229064
-
A Robertsonian translocation suppresses a somatic recombination pathway to loss of heterozygosity
-
DOI 10.1038/ng1055
-
Haigis KM. Dove WE A Robertson ian translocation suppresses a somatic recombination pathway to loss of heterozygosity. Nat Genet 2003; 33:33-39. (Pubitemid 36068679)
-
(2003)
Nature Genetics
, vol.33
, Issue.1
, pp. 33-39
-
-
Haigis, K.M.1
Dove, W.F.2
-
101
-
-
0037168610
-
Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC
-
DOI 10.1073/pnas.012679099
-
Sieber OM. Heinirnann K. Gorman P et al. Analysis of chromosomal instability in human colorecral adenomas with two mutational hits at APC. Proc Natl Acad Sci USA 2002; 99:16910-16915. (Pubitemid 36034072)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.26
, pp. 16910-16915
-
-
Sieber, O.M.1
Heinimann, K.2
Gorman, P.3
Lamlum, H.4
Crabtre, M.5
Simpson, C.A.6
Davies, D.7
Neale, K.8
Hodgson, S.V.9
Roylance, R.R.10
Phillips, R.K.S.11
Bodmer, W.F.12
Tomlinson, I.P.M.13
-
103
-
-
0020518746
-
Expression of recessive alleles by chromosomal mechanisms in retinoblastoma
-
Cavenee WK, Dryja TP. Phillips RA et al. Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature 1983; 305:779-784. (Pubitemid 13010953)
-
(1983)
Nature
, vol.305
, Issue.5937
, pp. 779-784
-
-
Cavenee, W.K.1
Dryja, T.P.2
Phillips, R.A.3
-
105
-
-
0035956878
-
Mechanisms underlying losses of heterozygosity in human colorectal cancers
-
DOI 10.1073/pnas.051625398
-
Thiagalingam S. Laken S. Willson JK et al. Mechanisms underlying losses of heterozygosity in human colorectal cancers. Proc Natl Acad Sci USA 2001; 98:2698-2702. (Pubitemid 32209545)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.5
, pp. 2698-2702
-
-
Thiagalingam, S.1
Laken, S.2
Willson, J.K.V.3
Markowitz, S.D.4
Kinzler, K.W.5
Vogelstein, B.6
Lengauer, C.7
-
106
-
-
0035110871
-
Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis
-
Shih IM. Zhou W, Goodman SN et al. Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis. Cancer Res 2001; 61:818-822. (Pubitemid 32174384)
-
(2001)
Cancer Research
, vol.61
, Issue.3
, pp. 818-822
-
-
Shih, I.-M.1
Zhou, W.2
Goodman, S.N.3
Lengauer, C.4
Kinzler, K.W.5
Vogelstein, B.6
-
107
-
-
33745244805
-
Frequent genetic and epigenetic abnormalities contribute to the deregulation of cytoglobin in non-small cell lung cancer
-
DOI 10.1093/hmg/ddl128
-
Xinarianos G. McRonald FE, Risk JM et al. Frequent genetic and epigenetic abnormalities contribute to the deregulation of cytoglobin in nonsmall cell lung cancer. Hum Mol Genet 2006; 15:2038-2044. (Pubitemid 43923394)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.13
, pp. 2038-2044
-
-
Xinarianos, G.1
McRonald, F.E.2
Risk, J.M.3
Bowers, N.L.4
Nikolaidis, G.5
Field, J.K.6
Liloglou, T.7
-
108
-
-
33645074134
-
Chromosomal instability in MYH- and APC-mutant adenomatous polyps
-
Cardoso J, Molenaar L, de Menezes RX et al. Chromosomal instability in MYH- and APC- mutant adenomatous polyps. Cancer Res 2006; 66:2514-2519.
-
(2006)
Cancer Res
, vol.66
, pp. 2514-2519
-
-
Cardoso, J.1
Molenaar, L.2
De Menezes, R.X.3
-
109
-
-
0037059043
-
The role of chromosomal instability in tumor initiation
-
DOI 10.1073/pnas.202617399
-
Nowak MA, Komarova NL. Sengupta A et al. The role of chromosomal instability in tumor initiation. Proc Natl Acad Sci USA 2002; 99:16226-16231. (Pubitemid 35462777)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.25
, pp. 16226-16231
-
-
Nowak, M.A.1
Komarova, N.L.2
Sengupta, A.3
Jallepalli, P.V.4
Shih, L.-M.5
Vogelstein, B.6
Lengauer, C.7
-
112
-
-
0346849717
-
Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC
-
DOI 10.1083/jcb.200307070
-
Green RA, Kaplan KB. Chromosome instability in colorectal tumor cells is associated with defects in microtubule plus-end attachments caused by a dominant mutation in APC. The Journal of Cell Biology 2003 ; 163:949-961. (Pubitemid 37541872)
-
(2003)
Journal of Cell Biology
, vol.163
, Issue.5
, pp. 949-961
-
-
Green, R.A.1
Kaplan, K.B.2
-
113
-
-
13444261036
-
Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability
-
DOI 10.1242/jcs.01556
-
Tighe A. Johnson VL, Taylor SS. Truncating APC mutations have dominant effects on proliferation. spindle checkpoint COntrol. survival and chromosome stability. J Cell Sci 2004; 117:6339-6353. (Pubitemid 40214561)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.26
, pp. 6339-6353
-
-
Tighe, A.1
Johnson, V.L.2
Taylor, S.S.3
-
114
-
-
20444490811
-
2-terminal fragments are the most stable part of the adenomatous polyposis coli protein and can be regulated by interactions with COOH-terminal domains
-
DOI 10.1158/0008-5472.CAN-04-4609
-
Li Z. Nathke IS. Tumor-associated NH2-terminal fragments are the most stable part of the adenomatous polyposis coli protein and can be regulated by interactions with COOH-terminal domalns. Cancer Res 2005; 65:5195-5204. (Pubitemid 40827329)
-
(2005)
Cancer Research
, vol.65
, Issue.12
, pp. 5195-5204
-
-
Li, Z.1
Nathke, I.S.2
-
115
-
-
0030703623
-
Apc gene mutation is associated with a dominant-negative effect upon intestinal cell migration
-
Mahmoud NN, Boolbol SK. Bilinski RT et al. APC Gene Mutation is Associated with a Dominant-Negative Effect upon Intestinal Cell Migration. Cancer Res 1997; 57:5045-5050. (Pubitemid 27498118)
-
(1997)
Cancer Research
, vol.57
, Issue.22
, pp. 5045-5050
-
-
Mahmoud, N.N.1
Boolbol, S.K.2
Bilinski, R.T.3
Martucci, C.4
Chadburn, A.5
Bertagnolli, M.M.6
-
116
-
-
0035914414
-
Progressive changes in adherens junction structure during intestinal adenoma formation in APC mutant mice
-
Carothers AM. Melstrom KA Jr. Mueller JD et al. Progressive changes in adherens junction structure during intestinal adenoma formation in APC mutant mice, J Biol Chem 2001; 276:39094-39102.
-
(2001)
J Biol Chem
, vol.276
, pp. 39094-39102
-
-
Carothers, A.M.1
Melstrom Jr., K.A.2
Mueller, J.D.3
-
118
-
-
0029069971
-
Evidence agalnst dominant negative mechanisms of intestinal polyp formation by APC gene mutations
-
Oshima M, Oshima H. KobayashiM et al. Evidence agalnst dominant negative mechanisms of intestinal polyp formation by APC gene mutations. Cancer Res 1995; 55:2719-2722.
-
(1995)
Cancer Res
, vol.55
, pp. 2719-2722
-
-
Oshima, M.1
Oshima, H.2
Kobayashi, M.3
-
119
-
-
18344367618
-
Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or "multiple" colorectal adenomas
-
DOI 10.1073/pnas.042699199
-
Sieber OM, Lamlum H. Crabtree MD et al. Whole-gene APC deletions cause classical familial adenomatous polyposis. but not attenuated polyposis or "multiple" colorectal adenomas. Proc Natl Acad Sci USA 2002; 99:2954-2958. (Pubitemid 34240567)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.5
, pp. 2954-2958
-
-
Sieber, O.M.1
Lamlum, H.2
Crabtree, M.D.3
Rowan, A.J.4
Barclay, E.5
Lipton, L.6
Hodgson, S.7
Thomas, H.J.W.8
Neale, K.9
Phillips, R.K.S.10
Farrington, S.M.11
Dunlop, M.G.12
Mueller, H.J.13
Bisgaard, M.L.14
Bulow, S.15
Fidalgo, P.16
Albuquerque, C.17
Scarano, M.I.18
Bodmer, W.19
Tomlinson, I.P.M.20
Heinimann, K.21
more..
-
120
-
-
13444253746
-
Large deletions of the APC gene in 15% of mutation-negative patients with classical polyposis (FAP): A Belgian study
-
DOI 10.1002/humu.20122
-
Michils G. Tejpar S, Thoelen Ret al. Large deletions of the APC gene in 15% of mutation-negative patients with classical polyposis (FAP): a Belgian study. Hum Mutat 2005; 25:125-134. (Pubitemid 40216608)
-
(2005)
Human Mutation
, vol.25
, Issue.2
, pp. 125-134
-
-
Michils, G.1
Tejpar, S.2
Thoelen, R.3
Van Cutsem, E.4
Vermeesch, J.R.5
Fryns, J.-P.6
Legius, E.7
Matthijs, G.8
-
123
-
-
0027363063
-
Genetic identification of Mom-1, a major modifier locus affecting Min- induced intestinal neoplasia in the mouse
-
DOI 10.1016/0092-8674(93)90484-8
-
Dietrich WF. Lander ES, Smith JS et al. Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse. Cell 1993; 75:631-639. (Pubitemid 23346362)
-
(1993)
Cell
, vol.75
, Issue.4
, pp. 631-639
-
-
Dietrich, W.F.1
Lander, E.S.2
Smith, J.S.3
Moser, A.R.4
Gould, K.A.5
Luongo, C.6
Borenstein, N.7
Dove, W.8
-
125
-
-
0030797904
-
Secretory phospholipase Pla2g2a confers resistance to intestinal tumorigenesis
-
DOI 10.1038/ng0997-88
-
Cormier RT, Hong KH, Halberg RB et al. Secretory phospholipase Pla2g2a confers resistanceto intestinal tumorigenesis. Nat Genet 1997; 17:88-91. (Pubitemid 27377538)
-
(1997)
Nature Genetics
, vol.17
, Issue.1
, pp. 88-91
-
-
Cormier, R.T.1
Hong, K.H.2
Halberg, R.B.3
Hawkins, T.L.4
Richardson, P.5
Mulherkar, R.6
Dove, W.F.7
Lander, E.S.8
-
126
-
-
0034729532
-
The Mom1(AKR) intestinal tumor resistance region consists of Pla2g2a and a locus distal to D4Mit64
-
AKR intestinal tumor resistance region consists of Pla2g2a and a locus distal to D4Mit64. Oncogene 2000; 19:3182-3192. (Pubitemid 30455930)
-
(2000)
Oncogene
, vol.19
, Issue.28
, pp. 3182-3192
-
-
Cormier, R.T.1
Bilger, A.2
Lillich, A.J.3
Halberg, R.B.4
Hong, K.H.5
Gould, K.A.6
Borenstein, N.7
Lander, E.S.8
Dove, W.F.9
-
127
-
-
33847056171
-
Expression of secretory phospholipase A2 in colon tumor cells potentiates tumor growth
-
Belinsky GS, Rajan TV, Saria EA et al. Expression of secretory phospholipase A2 in colon tumor cells potentiates tumor growth. Mol Carcinog 2007; 46:106-116.
-
(2007)
Mol Carcinog
, vol.46
, pp. 106-116
-
-
Belinsky, G.S.1
Rajan, T.V.2
Saria, E.A.3
-
128
-
-
0041665259
-
Aurora and the hunt for cancer-modifying genes
-
DOI 10.1038/ng0803-353
-
Dove W. Aurora and the hunt for cancer-modifying genes. Nat Genet 2003; 34:353-354. (Pubitemid 36935323)
-
(2003)
Nature Genetics
, vol.34
, Issue.4
, pp. 353-354
-
-
Dove, W.1
-
130
-
-
0029827781
-
Variants at the secretory phospholipase A2 (PLA2G2A) locus: Analysis of associations with familial adenomatous polyposis and sporadic colorectal tumours
-
Tomlinson IP. Beck NE, Neale K et al. Variants at the secretory phospholipase A2 (PLA2G2A) locus: analysis of associations with familial adenomatous polyposis and sporadic colorectal tumours. Ann Hum Genet 1996; 60(Pt 5):369-376. (Pubitemid 26383908)
-
(1996)
Annals of Human Genetics
, vol.60
, Issue.5
, pp. 369-376
-
-
Tomlinson, I.P.M.1
Beck, N.E.2
Neale, K.3
Bodmer, W.F.4
-
131
-
-
0030064510
-
2 genes that map to human chromosome IP35 -36 are not mutated in individuals with attenuated adenomatous polyposis coli
-
2 genes that map to human chromosome IP35 -36 are not mutated in individuals with attenuated adenomatous polyposis coli. Cancer Res 1996; 56:955-958.
-
(1996)
Cancer Res
, vol.56
, pp. 955-958
-
-
Spirio, L.N.1
Kutchera, W.2
Winstead, M.V.3
-
132
-
-
0028828611
-
Absence of secretory phospholipase A2 gene alterations in human colorectal cancer
-
Riggins GJ. Markowitz S. Wilson JK et al. Absence of secretory phospholipase A2 gene alterations in human colorectal cancer. Cancer Res 1995; 55:5184-5186.
-
(1995)
Cancer Res
, vol.55
, pp. 5184-5186
-
-
Riggins, G.J.1
Markowitz, S.2
Wilson, J.K.3
-
133
-
-
0030882943
-
Loss of the PLA2G2A gene in a sporadic colorectal tumor of a patient with a PLA2G2A germline mutation and absence of PLA2G2A germline alterations in patients with FAP
-
DOI 10.1007/s004390050514
-
Nimmrich I, Friedl W, Kruse R et al. Loss of the PLA2G2A gene in a sporadic colorecral tumor of a patient with a PLA2G2A gerrnline mutation and absence of PLA2G2A germline alteration s in patients with FAP. Hum Genet 1997; 100:345-349. (Pubitemid 27386838)
-
(1997)
Human Genetics
, vol.100
, Issue.3-4
, pp. 345-349
-
-
Nimmrich, I.1
Friedl, W.2
Kruse, R.3
Pietsch, S.4
Hentsch, S.5
Deuter, R.6
Winde, G.7
Muller, O.8
-
134
-
-
0037059002
-
Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis
-
DOI 10.1073/pnas.212646299
-
Leung SY,Chen X. Chu KM et al. Phospholipase A2 group IIA expression in gastric adenocarcinoma is associated with prolonged survival and less frequent metastasis. Proc Natl Acad Sci USA 2002; 99:16203-16208. (Pubitemid 35462773)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.25
, pp. 16203-16208
-
-
Leung, S.Y.1
Chen, X.2
Chu, K.M.3
Yuen, S.T.4
Mathy, J.5
Ji, J.6
Chan, A.S.Y.7
Li, R.8
Law, S.9
Troyanskaya, O.G.10
Tu, I.-P.11
Wong, J.12
So, S.13
Botstein, D.14
Brown, P.O.15
-
135
-
-
0036141923
-
Identification of the modifier of Min 2 (Mom2) locus, a new mutation that influences Apc-induced intestinal neoplasia
-
DOI 10.1101/gr.206002
-
Silverman KA, Koratkar R. Siracusa LD et al. identification of the modifier of Min 2 (Mom2) locus, a new mutation that influences APC-induced intestinal neoplasia. Genome Res 2002; 12:88-97. (Pubitemid 34065592)
-
(2002)
Genome Research
, vol.12
, Issue.1
, pp. 88-97
-
-
Silverman, K.A.1
Koratkar, R.2
Siracusa, L.D.3
Buchberg, A.M.4
-
136
-
-
20044373628
-
S mice
-
DOI 10.1073/pnas.0500039102
-
Min/+ Mom1S mice. Proc Natl Acad Sci USA 2005; 102:2868-2873. (Pubitemid 40299883)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.8
, pp. 2868-2873
-
-
Haines, J.1
Johnson, V.2
Pack, K.3
Suraweera, N.4
Slijepcevic, P.5
Cabuy, E.6
Coster, M.7
Ilyas, M.8
Wilding, J.9
Sieber, O.10
Bodmer, W.11
Tomlinson, I.12
Silver, A.13
-
137
-
-
0034975493
-
Mitotic recombination is suppressed by chromosomal divergence in hybrids of distantly related mouse strains
-
DOI 10.1038/88897
-
Shao C. Stambrook PJ. Tischfield JA. Mitotic recombination is suppressed by chromosomal divergence in hybrids of distantly related mouse strains. Nat Genet 2001; 28:169-172. (Pubitemid 32538064)
-
(2001)
Nature Genetics
, vol.28
, Issue.2
, pp. 169-172
-
-
Shao, C.1
Stambrook, P.J.2
Tischfield, J.A.3
-
138
-
-
15444370589
-
Min/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability
-
DOI 10.1073/pnas.0407822102
-
Rao CV, Yang YM, Swamy MV et al. Colonic tumorigenesis in BubRl+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability. PNAS 2005; 102:4365-4370. (Pubitemid 40397117)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.12
, pp. 4365-4370
-
-
Rao, C.V.1
Yang, Y.-M.2
Swamy, M.V.3
Liu, T.4
Fang, Y.5
Mahmood, R.6
Jhanwar-Uniyal, M.7
Dai, W.8
-
139
-
-
20144374299
-
Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice
-
DOI 10.1126/science.1108080
-
Sakatani T, Kaneda A. Iacobuzio-Donahue CA et al. Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice. Science 2005; 307:1976-1978. (Pubitemid 40404709)
-
(2005)
Science
, vol.307
, Issue.5717
, pp. 1976-1978
-
-
Sakatani, T.1
Kaneda, A.2
Iacobuzio-Donahue, C.A.3
Carter, M.G.4
De Boom Witzel, S.5
Okano, H.6
Ko, M.S.H.7
Ohlsson, R.8
Longo, D.L.9
Feinberg, A.P.10
-
140
-
-
0037436509
-
Loss of IGF2 imprinting: A potential marker of colorectal cancer risk
-
DOI 10.1126/science.1080902
-
Cui H, Cruz-Correa M, Giardiello FM et al. Loss of Igf2 imprinting: A potential marker of colorectal cancer risk. Science 2003; 299:1753-1755. (Pubitemid 36337205)
-
(2003)
Science
, vol.299
, Issue.5613
, pp. 1753-1755
-
-
Cui, H.1
Cruz-Correa, M.2
Giardiello, F.M.3
Hutcheon, D.F.4
Kafonek, D.R.5
Brandenburg, S.6
Wu, Y.7
He, X.8
Powe, N.R.9
Feinberg, A.P.10
-
141
-
-
0344826531
-
+/- compound mutant mice
-
DOI 10.1038/ng1265
-
Aokl K, Tarnal Y, Horiike S et al. Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+ /- compound mutant mice. Nat Genet 2003; 35:323-330. (Pubitemid 37486915)
-
(2003)
Nature Genetics
, vol.35
, Issue.4
, pp. 323-330
-
-
Aoki, K.1
Tamai, Y.2
Horiike, S.3
Oshima, M.4
Taketo, M.M.5
-
142
-
-
0037144601
-
Enhanced tumor formation in mice heterozygous for Blm mutation
-
Goss KH. Risinger MA. KordichJJ et al. Enhanced tumor formation in mice heterozygous for Blm mutation. Science 2002; 297:2051-2053.
-
(2002)
Science
, vol.297
, pp. 2051-2053
-
-
Goss, K.H.1
Risinger, M.A.2
Kordich, J.J.3
-
143
-
-
0033667704
-
Cancer predisposition caused by elevated mirotic recombination in Bloom mice
-
Luo G, Santoro IM, McDaniel LD et al. Cancer predisposition caused by elevated mirotic recombination in Bloom mice. Nat Genet 2000 ; 26:424-429.
-
(2000)
Nat Genet
, vol.26
, pp. 424-429
-
-
Luo, G.1
Santoro, I.M.2
McDaniel, L.D.3
-
144
-
-
15544389502
-
Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome
-
DOI 10.1093/hmg/ddi075
-
Mann MB, Hodges CA, Barnes E et al. Defective sister-chromatid cohesion, aneuploidy and cancer predisposition in a mouse model of type II Rothmund-Thomson syndrome. Hum Mol Genet 2005 ; 14:813-825. (Pubitemid 40403277)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.6
, pp. 813-825
-
-
Mann, M.B.1
Hodges, C.A.2
Barnes, E.3
Vogel, H.4
Hassold, T.J.5
Luo, G.6
-
145
-
-
0037603586
-
Deficiency of Mbd2 suppresses intestinal tumorigenesis
-
DOI 10.1038/ng1155
-
Sansom OJ, Berger J, Bishop SM et al. Deficiency of Mbd2 suppresses intestinal tumorigenesis. Nat Genet 2003; 34:145-147. (Pubitemid 36666922)
-
(2003)
Nature Genetics
, vol.34
, Issue.2
, pp. 145-147
-
-
Sansom, O.J.1
Berger, J.2
Bishop, S.M.3
Hendrich, B.4
Bird, A.5
Clarke, A.R.6
-
146
-
-
0037135130
-
Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice
-
DOI 10.1126/science.1073354
-
Millar CB, Guy J, Sansom OJ et al. Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice. Science 2002 ; 297:403-405. (Pubitemid 34790770)
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 403-405
-
-
Millar, C.B.1
Guy, J.2
Sansom, O.J.3
Selfridge, J.4
MacDougall, E.5
Hendrich, B.6
Keightley, P.D.7
Bishop, S.M.8
Clarke, A.R.9
Bird, A.10
-
147
-
-
21344460054
-
EphB receptor activity suppresses colorectal cancer progression
-
DOI 10.1038/nature03626
-
Ballie E, Bacani J, Begrhcl H et al. EphB receptor activity suppresses colorecral cancer progression. Nature 2005; 435:1126-1130. (Pubitemid 40910522)
-
(2005)
Nature
, vol.435
, Issue.7045
, pp. 1126-1130
-
-
Batlle, E.1
Bacani, J.2
Begthel, H.3
Jonkeer, S.4
Gregorieff, A.5
Van De Born, M.6
Malats, N.7
Sancho, E.8
Boon, E.9
Pawson, T.10
Gallinger, S.11
Pals, S.12
Clevers, H.13
-
148
-
-
0023572211
-
The gene for familial polyposis coli maps to the long arm of chromosome 5
-
Leppert M, Dobbs M, Scarnbler P et al. The gene for familial polyposis coli maps to the long arm of chromosome 5. Science 1987; 238:1411-1413. (Pubitemid 18015963)
-
(1987)
Science
, vol.238
, Issue.4832
, pp. 1411-1413
-
-
Leppert, M.1
Dobbs, M.2
Scambler, P.3
O'Connell, P.4
Nakamura, Y.5
Stauffer, D.6
Woodward, S.7
Burt, R.8
Hughes, J.9
Gardner, E.10
Lathrop, M.11
Wasmuth, J.12
Lalouel, J.-M.13
White, R.14
-
149
-
-
0029047954
-
Loss of APC heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated APC gene
-
Oshima M, Oshima H, Kitagawa K et al. Loss of APC heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated APC gene. Proc Natl Acad Sci USA 1995; 92:4482-4486.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4482-4486
-
-
Oshima, M.1
Oshima, H.2
Kitagawa, K.3
-
150
-
-
33645786979
-
Imaging cyclooxygenase-2 (Cox-2) gene expression in living animals with a Iuclferase knock-in reporter gene
-
Ishikawa TO, Jaln NK, Takero MM et al. Imaging cyclooxygenase-2 (Cox-2) gene expression in living animals with a Iuclferase knock-in reporter gene. Mol Imaging Biol 2006; 8:171-187.
-
(2006)
Mol Imaging Biol
, vol.8
, pp. 171-187
-
-
Ishikawa, T.O.1
Jaln, N.K.2
Takero, M.M.3
-
151
-
-
4744368614
-
Min intestinal tumorigenesis
-
DOI 10.1016/j.ygeno.2004.07.010, PII S0888754304001995
-
Min intestinal tumorigenesis. Genornics 2004; 84:844-852. (Pubitemid 39314444)
-
(2004)
Genomics
, vol.84
, Issue.5
, pp. 844-852
-
-
Koratkar, R.1
Silverman, K.A.2
Pequignot, E.3
Hauck, W.W.4
Buchberg, A.M.5
Siracusa, L.D.6
-
152
-
-
0036792184
-
Min intestinal polyps, independent of the resistant Modifier of Min 1 (MomlR) locus
-
Min intestinal polyps, independent of the resistant Modifier of Min 1 (MomlR) locus. Cancer Res 2002; 62:5413-5417.
-
(2002)
Cancer Res
, vol.62
, pp. 5413-5417
-
-
Koratkar, R.1
Pequignot, E.2
Hauck, W.W.3
-
153
-
-
0034978564
-
Telomere dysfunction and evolution of intestinal carcinoma in mice and humans
-
DOI 10.1038/88871
-
Rudolph KL, Millard M, Bosenberg MW et al. Telomere dysfunction and evolution of intestinal carcinoma in mice and humans. Nat Genet 2001; 28:155-159. (Pubitemid 32538061)
-
(2001)
Nature Genetics
, vol.28
, Issue.2
, pp. 155-159
-
-
Rudolph, K.L.1
Millard, M.2
Bosenberg, M.W.3
DePinho, R.A.4
-
154
-
-
0032521201
-
Enhanced intestinal adenomatous polyp formation in Pms2(-/-);Min mice
-
-/-; Min mice. Cancer Res 1998; 58:1087-1089. (Pubitemid 28183187)
-
(1998)
Cancer Research
, vol.58
, Issue.6
, pp. 1087-1089
-
-
Baker, S.M.1
Harris, A.C.2
Tsao, J.-L.3
Flath, T.J.4
Bronner, C.E.5
Gordon, M.6
Shibata, D.7
Liskay, R.M.8
-
156
-
-
8944262831
-
MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis
-
Reitrnalr AH, Cal JC, Bjerknes M et al. MSH2 deficiency contributes to accelerated APC-Cvrnediared intestinal tumorigenesis. Cancer Res 1996; 56:2922-2926. (Pubitemid 26199732)
-
(1996)
Cancer Research
, vol.56
, Issue.13
, pp. 2922-2926
-
-
Reitmair, A.H.1
Cai, J.-C.2
Bjerknes, M.3
Redston, M.4
Cheng, H.5
Pind, M.T.L.6
Hay, K.7
Mitri, A.8
Bapat, B.V.9
Mak, T.W.10
Gallinger, S.11
-
157
-
-
0035503172
-
1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis
-
1638Nmice define the roles of MSH3 and MSH6 in DNA repalr and intestinal tumorigenesis. Cancer Res 2001 ; 61:7934-7942. (Pubitemid 33049384)
-
(2001)
Cancer Research
, vol.61
, Issue.21
, pp. 7934-7942
-
-
Kuraguchi, M.1
Yang, K.2
Wong, E.3
Avdievich, E.4
Fan, K.5
Kolodner, R.D.6
Lipkin, M.7
Brown, A.M.C.8
Kucherlapati, R.9
Edelmann, W.10
-
158
-
-
0037162498
-
Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression
-
DOI 10.1073/pnas.152321699
-
Kucherlapati M, Yang K, Kuraguchi M et al. Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression. PNAS 2002 ; 99:9924-9929. (Pubitemid 34831149)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.15
, pp. 9924-9929
-
-
Kucherlapati, M.1
Yang, K.2
Kuraguchi, M.3
Zhao, J.4
Lia, M.5
Heyer, J.6
Kane, M.F.7
Fan, K.8
Russell, R.9
Brown, A.M.C.10
Kneitz, B.11
Edelmann, W.12
Kolodner, R.D.13
Lipkin, M.14
Kucherlapati, R.15
-
159
-
-
10844274799
-
Min/+) mice
-
DOI 10.1158/0008-5472.CAN-04-2958
-
Sieber OM, Howarth KM, Thirlwell C et al.Myh deficiency enhances intestinal tumorigenesis in multiple int estinal neoplasia (ApcMin/ +) mice. Cancer Res 2004 ; 64:8876-8881. (Pubitemid 39665492)
-
(2004)
Cancer Research
, vol.64
, Issue.24
, pp. 8876-8881
-
-
Sieber, O.M.1
Howarth, K.M.2
Thirlwell, C.3
Rowan, A.4
Mandir, N.5
Goodlad, R.A.6
Gilkar, A.7
Spencer-Dene, B.8
Stamp, G.9
Johnson, V.10
Silver, A.11
Yang, H.12
Miller, J.H.13
Ilyas, M.14
Tomlinson, I.P.M.15
-
162
-
-
24644478136
-
Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development
-
DOI 10.1038/nature03914
-
Nateri AS, Spencer-Dene B, Behrens A. Interaction of phosphorylated c-jun with TCF4 regulates intestinal cancer development. Nature 2005 ; 437:281-285. (Pubitemid 41294493)
-
(2005)
Nature
, vol.437
, Issue.7056
, pp. 281-285
-
-
Nateri, A.S.1
Spencer-Dene, B.2
Behrens, A.3
-
163
-
-
4344689970
-
Min mice
-
DOI 10.1128/MCB.24.17.7598-7611.2004
-
Hulit J, Wang C, Li Z et al. Cyclin Digenetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice. Mol Cell Biol 2004 ; 24:7598-7611. (Pubitemid 39121486)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.17
, pp. 7598-7611
-
-
Hulit, J.1
Wang, C.2
Li, Z.3
Albanese, C.4
Rao, M.5
Di Vizio, D.6
Shah, S.7
Byers, S.W.8
Mahmood, R.9
Augenlicht, L.H.10
Russell, R.11
Pestell, R.G.12
-
164
-
-
0037022292
-
Importance of epidermal growth factor receptor signaling in establishment of adenomas and malntenance of carcinomas during intestina l tumorigenesis
-
Roberts RE, Min L, Washington MK et al. Importance of epidermal growth factor receptor signaling in establishment of adenomas and malntenance of carcinomas during intestina l tumorigenesis. Proc Natl Acad Sci USA 2002 ; 99:152 1-1526.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.152
, pp. 1-1526
-
-
Roberts, R.E.1
Min, L.2
Washington, M.K.3
-
165
-
-
0035863515
-
WAF1/cip1 gene enhances Apc-initiated tumor formation and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosa
-
Yang WC. Mathew J, Velcich A et al. Targeted Inactivation of the p21WAF1/cip1 gene enhances APC-initiated tumor formarion and the tumor-promoting activity of a Western-style high-risk diet by altering cell maturation in the intestinal mucosa. Cancer Res 2001 ; 61:565-569. (Pubitemid 32128615)
-
(2001)
Cancer Research
, vol.61
, Issue.2
, pp. 565-569
-
-
Wan Cai Yang1
Mathew, J.2
Velcich, A.3
Edelmann, W.4
Kucherlapati, R.5
Lipkin, M.6
Yang, K.7
Augenlicht, L.H.8
-
166
-
-
0036559462
-
Pathway-specific tumor suppression: Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice
-
DOI 10.1016/S1535-6108(02)00054-5
-
Philipp -Sraheli J, Kim KH, Payne SR et al. Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in APC mutant mice, but not in Smad3 mutant mice. Cancer Cell 2002 ; 1:355-368. (Pubitemid 41039137)
-
(2002)
Cancer Cell
, vol.1
, Issue.4
, pp. 355-368
-
-
Philipp-Staheli, J.1
Kim, K.-H.2
Payne, S.R.3
Gurley, K.E.4
Liggitt, D.5
Longton, G.6
Kemp, C.J.7
-
167
-
-
0034724315
-
Tumorigenesis in the multiple intestinal neoplasia mouse: Redundancy of negative regulators and specificity of modifiers
-
DOI 10.1073/pnas.050585597
-
Halberg RE. Karzung OS, Hoff PD et al. Tumorigenesis in the multiple int estinal neoplasia mouse: redundancy of negative regulators and specificity of modifiers. Proc Natl Acad Sci USA 2000 ; 97:3461-3466. (Pubitemid 30183325)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.7
, pp. 3461-3466
-
-
Halberg, R.B.1
Katzung, D.S.2
Hoff, P.D.3
Moser, A.R.4
Cole, C.E.5
Lubet, R.A.6
Donehower, L.A.7
Jacoby, R.F.8
Dove, W.F.9
-
168
-
-
0031036359
-
Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin
-
DOI 10.1073/pnas.94.4.1402
-
Wilson CL, Heppner KJ, Labosky PA et al. Intestinal tumorigenesis is suppressed in mice lacking the metalloprote inase marrilysin. Proc Natl Acad Sci USA 1997; 94:1402-1407. (Pubitemid 27087863)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.4
, pp. 1402-1407
-
-
Wilson, C.L.1
Heppner, K.J.2
Labosky, P.A.3
Hogan, B.L.M.4
Matrisian, L.M.5
-
169
-
-
0037066706
-
Absence of post-translational aspartyl β-hydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia
-
DOI 10.1074/jbc.M110389200
-
Dinchuk JE, Focht RJ, Kelley JA et al. Absence of posttranslational aspartyl βhydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia. J Bioi Chern 2002; 277:12970-12977 (Pubitemid 34952665)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.15
, pp. 12970-12977
-
-
Dinchuk, J.E.1
Focht, R.J.2
Kelley, J.A.3
Henderson, N.L.4
Zolotarjova, N.I.5
Wynn, R.6
Neff, N.T.7
Link, J.8
Huber, R.M.9
Burn, T.C.10
Rupar, M.J.11
Cunningham, M.R.12
Selling, B.H.13
Ma, J.14
Stern, A.A.15
Hollis, G.F.16
Stein, R.B.17
Friedman, P.A.18
-
170
-
-
0033778728
-
E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice
-
Smits R, Ruiz P, Diaz-Cano S et al. E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice. Gastroenterology 2000; 119:1045-1053.
-
(2000)
Gastroenterology
, vol.119
, pp. 1045-1053
-
-
Smits, R.1
Ruiz, P.2
Diaz-Cano, S.3
-
171
-
-
2442708845
-
Peroxisome proliferator-activated receptor-δ attenuates colon carcinogenesis
-
DOI 10.1038/nm1026
-
Harman FS, Nicol CJ, Marin HE et al, Peroxisome proliferator-activated receptor-[delta] attenuates colon carcinogenesis. Nat Med 2004; 10:481-483. (Pubitemid 38667905)
-
(2004)
Nature Medicine
, vol.10
, Issue.5
, pp. 481-483
-
-
Harman, F.S.1
Nicol, C.J.2
Marin, H.E.3
Ward, J.M.4
Gonzalez, F.J.5
Peters, J.M.6
-
172
-
-
4544283421
-
Netrin-1 controls colorectal tumorigenesis by regulating apoptosis
-
DOI 10.1038/nature02788
-
Mazelin L, Bernet A, Bonod-Bidaud C et al. Nerrin-1 controls colorectal tumorigenesis by regulating apoptosis. Nature 2004; 431:80-84. (Pubitemid 39215111)
-
(2004)
Nature
, vol.430
, Issue.7004
, pp. 80-84
-
-
Mazelin, L.1
Bernst, A.2
Bonod-Bidaud, C.3
Pays, L.4
Arnaud, S.5
Gespach, C.6
Bredesen, D.E.7
Scoazec, J.-Y.8
Mehlen, P.9
-
173
-
-
0033572255
-
Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice
-
Takaku K, Miyoshi H, Matsunaga A et al. Gastric and duodenal polyps in Smad4 (Dpc4) knockout mice. Cancer Res 1999; 59:6113-6117. (Pubitemid 30035630)
-
(1999)
Cancer Research
, vol.59
, Issue.24
, pp. 6113-6117
-
-
Takaku, K.1
Miyoshi, H.2
Matsunaga, A.3
Oshima, M.4
Sasaki, N.5
Taketo, M.M.6
-
174
-
-
0242468125
-
Five new mouse susceptibility to colon cancer loci, Scc11-Scc15
-
DOI 10.1038/sj.onc.1207096
-
Ruivenkamp CAL, Csikos T, Klous AM et al. Five new mouse susceptibility to colon cancer loci, Scc11-Scc15. Oncogene 2003; 22:7258-7260. (Pubitemid 37378559)
-
(2003)
Oncogene
, vol.22
, Issue.46
, pp. 7258-7260
-
-
Ruivenkamp, C.A.L.1
Csikos, T.2
Klous, A.M.3
Van Wezel, T.4
Demant, P.5
|