A chemoprotective fish oil- and pectin-containing diet temporally alters gene expression profiles in exfoliated rat colonocytes throughout Oncogenesis

Journal of Nutrition

Volumn 141, Issue 6, 2011, Pages 1029-1035

  Cho, Youngmi ^a   Kim, Hyemee ^a   Turner, Nancy D ^a   Mann, John C ^a   Wei, Jiawei ^a   Taddeo, Stella S ^a   Davidson, Laurie A ^a   Wang, Naisyin ^b   Vannucci, Marina ^c   Carroll, Raymond J ^a   Chapkin, Robert S ^a   Lupton, Joanne R ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c Rice University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 ALKYL 2 ACETYLGLYCEROPHOSPHOCHOLINE ESTERASE; ADAM3 PROTEIN; AMYLOID BETA PRECURSOR PROTEIN; BREAST CANCER METASTASIS SUPPRESSOR 1 PROTEIN; BULLOUS PEMPHIGOID ANTIGEN 1; CELL DIVISION CYCLE 34 HOMOLOG PROTEIN; CELLULOSE; CORN OIL; CYCLIN DEPENDENT KINASE INHIBITOR 1C; CYCLIN G1; CYCLIN K; CYCLIN L1; CYCLIN T2; DNA DAMAGE INDUCIBLE TRANSCRIPT 3 PROTEIN; FISH OIL; GLYCOGEN SYNTHASE KINASE 3BETA; GROWTH ARREST SPECIFIC 7 PROTEIN; GROWTH FACTOR INDEPENDENT 1B; INTERLEUKIN 23P19; NEURITIN; NUCLEAR DISTRIBUTION GENE E HOMOLOG 1 PROTEIN; PECTIN; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PROTEIN; RETINOBLASTOMA BINDING PROTEIN 6; RETINOBLASTOMA LIKE 2 PROTEIN; RUVB LIKE PROTEIN 1; SPINDLIN 1; SYNTAXIN 1A; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ABERRANT CRYPT FOCUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALORIC INTAKE; CANCER PREVENTION; CELL ADHESION; CELL CYCLE REGULATION; COLON; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; DOWN REGULATION; FECES ANALYSIS; GENE EXPRESSION PROFILING; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; UPREGULATION;

ANIMALS; AZOXYMETHANE; CELL CYCLE; CELL PROLIFERATION; COLONIC NEOPLASMS; DIET; DIETARY FATS, UNSATURATED; DIETARY SUCROSE; ENTEROCYTES; FECES; FISH OILS; GENE EXPRESSION PROFILING; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PECTINS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER;

RATTUS; ZEA MAYS;

EID: 79958205937     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.110.134973     Document Type: Article

References (47)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin. 2009;59:225-49.
2. Cummings JH, Bingham SA. Diet and the prevention of cancer. BMJ. 1998;317:1636-40.
3. Chang WC, Chapkin RS, Lupton JR. Predictive value of proliferation, differentiation and apoptosis as intermediate markers for colon tumorigenesis. arcinogenesis. 1997;18:721-30.
4. Hong MY, Lupton JR, Morris JS, Wang N, Carroll RJ, Davidson LA, Elder RH, Chapkin RS. Dietary fish oil reduces O6-methylguanine DNA adduct levels in rat colon in part by increasing apoptosis during tumor initiation. Cancer Epidemiol Biomarkers Prev. 2000;9:819-26.
5. Vanamala J, Glagolenko A, Yang P, Carroll RJ, Murphy ME, Newman RA, Ford JR, Braby LA, Chapkin RS, et al. Dietary fish oil and pectin enhance colonocyte apoptosis in part through suppression of PPARdelta/ PGE2 and elevation of PGE3. Carcinogenesis. 2008;29:790-6.
6. Chang WL, Chapkin RS, Lupton JR. Fish oil blocks azoxymethaneinduced rat colon tumorigenesis by increasing cell differentiation and apoptosis rather than decreasing cell proliferation. J Nutr. 1998;128: 491-7.
7. Bloom J, Cross FR. Multiple levels of cyclin specificity in cell-cycle control. Nat Rev Mol Cell Biol. 2007;8:149-60.
8. Crim KC, Sanders LM, Hong MY, Taddeo SS, Turner ND, Chapkin RS, Lupton JR. Upregulation of p21Waf1/Cip1 expression in vivo by butyrate administration can be chemoprotective or chemopromotive depending on the lipid component of the diet. Carcinogenesis. 2008;29: 1415-20.
9. Stupack DG, Cheresh DA. Get a ligand, get a life: integrins, signaling and cell survival. J Cell Sci. 2002;115:3729-38.
10. Huerta S, Goulet EJ, Livingston EH. Colon cancer and apoptosis. Am J Surg. 2006;191:517-26.
11. Davidson LA, Nguyen DV, Hokanson RM, Callaway ES, Isett RB, Turner ND, Dougherty ER, Wang N, Lupton JR, et al. Chemopreventive n-3 polyunsaturated fatty acids reprogram genetic signatures during colon cancer initiation and progression in the rat. Cancer Res. 2004;64:6797-804.
12. Hong MY, Chapkin RS, Davidson LA, Turner ND, Morris JS, Carroll RJ, Lupton JR. Fish oil enhances targeted apoptosis during colon tumor initiation in art by downregulating Bcl-2. Nutr Cancer. 2003;46: 44-51.
13. Davidson LA, Jiang YH, Lupton JR, Chapkin RS. Noninvasive detection of putative biomarkers for colon cancer using fecal messenger RNA. Cancer pidemiol Biomarkers Prev. 1995;4:643-7.
14. Davidson LA, Aymond CM, Jiang YH, Turner ND, Lupton JR, Chapkin RS. Non-invasive detection of fecal protein kinase C betaII and zeta messenger RNA: putative biomarkers for colon cancer. Carcinogenesis. 1998;19:253-7.
15. Zhao C, Ivanov I, Dougherty ER, Hartman TJ, Lanza E, Bobe G, Colburn NH, Lupton JR, Davidson LA, et al. Noninvasive detection of candidate molecular biomarkers in subjects with a history of insulin resistance and colorectal adenomas. Cancer Prev Res (Phila). 2009;2: 590-7.
16. Chapkin RS, Zhao C, Ivanov I, Davidson LA, Goldsby JS, Lupton JR, Mathai RA, Monaco MH, Rai D, et al. Noninvasive stool-based detection of infant gastrointestinal development using gene expression profiles from exfoliated epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2010;298:G582-9.
17. Vanamala J, Leonardi T, Patil BS, Taddeo SS, Murphy ME, Pike LM, Chapkin RS, Lupton JR, Turner ND. Suppression of colon carcinogenesis by ioactive compounds in grapefruit. Carcinogenesis. 2006;27: 1257-65.
18. Raffel J, Bhattacharyya AK, Gallegos A, Cui H, Einspahr JG, Alberts DS, Powis G. Increased expression of thioredoxin-1 in human colorectal cancer is associated with decreased patient survival. J Lab Clin Med. 2003;142:46-51.
19. Guzinska-Ustymowicz K, Zalewski B, Kasacka I, Piotrowski Z, Skrzydlewska E. Activity of cathepsin B and D in colorectal cancer: relationships with umour budding. Anticancer Res. 2004;24:2847-51.
20. Babyatsky M, Lin J, Yio X, Chen A, Zhang JY, Zheng Y, Twyman C, Bao X, Schwartz M, et al. Trefoil factor-3 expression in human colon cancer liver etastasis. Clin Exp Metastasis. 2009;26:143-51.
21. Liu LY, Wang N, Lupton JR, Turner ND, Chapkin RS, Davidson LA. A two-stage normalization method for partially degraded mRNA microarray data. ioinformatics. 2005;21:4000-6.
22. Benjamini Y, Hochberg Y. Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing. Journal of the Royal Statistical ociety. Series B (Statistical Methodological). 1995; 57:289-300.
23. Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc. 009;4:44-57.
24. Hong MY, Chapkin RS, Wild CP, Morris JS, Wang N, Carroll RJ, Turner ND, Lupton JR. Relationship between DNA adduct levels, repair enzyme, and apoptosis as a function of DNA methylation by azoxymethane. Cell Growth Differ. 1999;10:749-58.
25. Chao C, Jamshidi-Parsian A, Wang WW, McMasters KM. Colorectal cancer cell adhesion attenuates Ad-E2F-1 mediated apoptosis. J Surg Res. 2003;113:81-7.
26. Polyak K, Hamilton SR, Vogelstein B, Kinzler KW. Early alteration of cellcycle-regulated gene expression in colorectal neoplasia. Am J Pathol. 1996; 49:381-7.
27. Litovchick L, Chestukhin A, DeCaprio JA. Glycogen synthase kinase 3 phosphorylates RBL2/p130 during quiescence. Mol Cell Biol. 2004;24: 8970-80.
28. Lauscher JC, Loddenkemper C, Kosel L, Grone J, Buhr HJ, Huber O. Increased pontin expression in human colorectal cancer tissue. Hum Pathol. 2007;38:978-85.
29. Nicolaides NC, Papadopoulos N, Liu B,Wei YF, Carter KC, Ruben SM, Rosen CA, Haseltine WA, Fleischmann RD, et al. Mutations of two PMS homologues in hereditary nonpolyposis colon cancer. Nature. 1994;371: 75-80.
30. Tutton MG, George ML, Eccles SA, Burton S, Swift RI, Abulafi AM. Use of plasma MMP-2 and MMP-9 levels as a surrogate for tumour expression in olorectal cancer patients. Int J Cancer. 2003;107:541-50.
31. Norton JD, Atherton GT. Coupling of cell growth control and apoptosis functions of Id proteins. Mol Cell Biol. 1998;18:2371-81.
32. Xu JX, Morii E, Liu Y, Nakamichi N, Ikeda J, Kimura H, Aozasa K. High tolerance to apoptotic stimuli induced by serum depletion and ceramide in side-population cells: high expression of CD55 as a novel character for side-population. Exp Cell Res. 2007;313:1877-85.
33. Kitamura S, Kondo S, Shinomura Y, Kanayama S,Miyazaki Y, Kiyohara T, Hiraoka S, Matsuzawa Y. Met/HGF receptormodulates bcl-wexpression and inhibits apoptosis in human colorectal cancers. Br J Cancer. 2000;83: 668-73.
34. Zhang Y, Chan DC. New insights into mitochondrial fusion. FEBS Lett. 2007;581:2168-73.
35. Hong MY, Chapkin RS, Barhoumi R, Burghardt RC, Turner ND, Henderson CE, Sanders LM, Fan YY, Davidson LA, et al. Fish oil increases mitochondrial phospholipid unsaturation, upregulating reactive oxygen species and apoptosis in rat colonocytes. Carcinogenesis. 2002;23:1919-25.
36. Sanders LM, Henderson CE, Hong MY, Barhoumi R, Burghardt RC, Wang N, Spinka CM, Carroll RJ, Turner ND, et al. An increase in reactive oxygen species by dietary fish oil coupled with the attenuation of antioxidant defenses by dietary pectin enhances rat colonocyte apoptosis. J Nutr. 2004;134:3233-8.
37. Latham P, Lund EK, Johnson IT. Dietary n-3 PUFA increases the apoptotic response to 1,2-dimethylhydrazine, reduces mitosis and suppresses the induction of carcinogenesis in the rat colon. Carcinogenesis. 1999;20: 645-50.
38. Ng Y, Barhoumi R, Tjalkens RB, Fan YY, Kolar S, Wang N, Lupton JR, Chapkin RS. The role of docosahexaenoic acid in mediating mitochondrial membrane lipid oxidation and apoptosis in colonocytes. Carcinogenesis. 2005;26:1914-21.
39. Fan YY, Zhan Y, Aukema HM, Davidson LA, Zhou L, Callaway E, Tian Y,Weeks BR, Lupton JR, et al. Proapoptotic effects of dietary (n-3) fatty acids are enhanced in colonocytes of manganese-dependent superoxide dismutase knockout mice. J Nutr. 2009;139:1328-32.
40. Kolar SS, Barhoumi R, Lupton JR, Chapkin RS. Docosahexaenoic acid and butyrate synergistically induce colonocyte apoptosis by enhancing mitochondrial a2+ accumulation. Cancer Res. 2007;67:5561-8.
41. Kolar SS, Barhoumi R, Callaway ES, Fan YY, Wang N, Lupton JR, Chapkin RS. Synergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca(2+) accumulation in colonocytes. Am J Physiol Gastrointest Liver Physiol. 2007;293: G935-43.
42. Kumarakulasingham M, Rooney PH, Dundas SR, Telfer C, Melvin WT, Curran S, Murray GI. Cytochrome p450 profile of colorectal cancer: identification of arkers of prognosis. Clin Cancer Res. 2005;11: 3758-65.
43. Zhang S, Lin QD, Di W. Suppression of human ovarian carcinoma metastasis by the metastasis-suppressor gene, BRMS1. Int J Gynecol Cancer. 2006;16:522-31.
44. Arribas J, Bech-Serra JJ, Santiago-Josefat B. ADAMs, cell migration and cancer. Cancer Metastasis Rev. 2006;25:57-68.
45. Gao S, Scott RE. P2P-R protein overexpression restricts mitotic progression at prometaphase and promotes mitotic apoptosis. J Cell Physiol. 2002; 93:199-207.
46. Xiao R, Badger TM, Simmen FA. Dietary exposure to soy or whey proteins alters colonic global gene expression profiles during rat colon tumorigenesis. Mol ancer. 2005;4:1.
47. Kachroo P, Ivanov I, Davidson LA, Chowdhary BP, Lupton JR, Chapkin RS. Classification of diet-modulated gene signatures at the colon cancer initiation and progression stages. Dig Dis Sci. 2011; DOI 10.1007/ s10620-011-1652-8.