Electrically-assisted delivery of an anionic protein across intact skin: Cathodal iontophoresis of biologically active ribonuclease T1

Journal of Controlled Release

Volumn 152, Issue 3, 2011, Pages 356-362

  Dubey, S ^a   Kalia, Y N ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Iontophoresis; Non invasive; Protein delivery; RNAse T1; Transdermal

Indexed keywords

IONTOPHORESIS; NON-INVASIVE; PROTEIN DELIVERY; RNASE T1; TRANSDERMAL;

BINDING SITES; CATHODES; CONFOCAL MICROSCOPY; ELECTRIC VEHICLES; ELECTROMIGRATION; ELECTROOSMOSIS; ELECTROPHORESIS; ENZYME ACTIVITY; MOLECULAR WEIGHT; PROTEINS;

ELECTROTHERAPEUTICS;

CATION; DEXTRAN; OSMOTIC AGENT; PARACETAMOL; RIBONUCLEASE A; RIBONUCLEASE T1;

ANIMAL TISSUE; ARTICLE; CATION TRANSPORT; CONTROLLED STUDY; DENSITY; DRUG DELIVERY SYSTEM; EAR; ENZYME ACTIVITY; ENZYME STRUCTURE; FEASIBILITY STUDY; FLUID FLOW; IONTOPHORESIS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; SKIN; SKIN PERMEABILITY; SWINE;

ACETAMINOPHEN; ANIMALS; ANIONS; DERMIS; DEXTRANS; ELECTRICITY; ELECTRODES; EPIDERMIS; FLUORESCEIN-5-ISOTHIOCYANATE; IONTOPHORESIS; MICROSCOPY, FLUORESCENCE; PERMEABILITY; PROTEINS; RIBONUCLEASE T1; RIBONUCLEASE, PANCREATIC; SKIN; SKIN ABSORPTION; STATIC ELECTRICITY; SURFACE PROPERTIES; SUS SCROFA;

EID: 79958187550     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.03.004     Document Type: Article

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