Transdermal iontophoresis of dexamethasone sodium phosphate in vitro and in vivo: Effect of experimental parameters and skin type on drug stability and transport kinetics

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 75, Issue 2, 2010, Pages 173-178

  Cazares Delgadillo J ^a   Balaguer Fernandez C ^b   Calatayud Pascual, A ^b   Ganem Rondero, A ^c   Quintanar Guerrero, D ^c   Lopez Castellano A C ^b   Merino, V ^d   Kalia, Y N ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSIDAD CEU CARDENAL HERRERA   (Spain)

^c UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^d UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Antiemetics; Dexamethasone sodium phosphate; Iontophoresis; Pharmacokinetics; Transdermal

Indexed keywords

DEXAMETHASONE SODIUM PHOSPHATE; SILVER; SILVER CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHEMOTHERAPY INDUCED EMESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DERMATOME; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG METABOLISM; DRUG PENETRATION; DRUG STABILITY; DRUG STRUCTURE; DRUG TRANSPORT; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; IONTOPHORESIS; MALE; NONHUMAN; RAT; SKIN PERMEABILITY; SKIN SURFACE; SPECIES DIFFERENCE; STEADY STATE; TRANSPORT KINETICS; WISTAR RAT;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTINEOPLASTIC AGENTS; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG STABILITY; GLUCOCORTICOIDS; HUMANS; HYDROLYSIS; IONTOPHORESIS; MALE; RATS; RATS, WISTAR; SKIN; SKIN ABSORPTION; SPECIES SPECIFICITY; SWINE; TIME FACTORS; VOMITING;

EID: 77952956861     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2010.03.011     Document Type: Article

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