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Volumn 19, Issue 2, 2011, Pages 63-74

Regulation of gap junctional communication by astrocytic mitochondrial K ATP channels following neurotoxin administration in in vitro and in vivo models

Author keywords

Astrocyte; Epilepsy; Gap junction intercellular communication; Mitochondrial K ATP channel; Neurotoxin; Picrotoxin; Spatial buffering

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CONNEXIN 30; CONNEXIN 36; CONNEXIN 43; CONNEXIN 45; DIAZOXIDE; KAINIC ACID; NEUROTOXIN;

EID: 79958101372     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000323575     Document Type: Article
Times cited : (12)

References (60)
  • 1
    • 9444223977 scopus 로고    scopus 로고
    • + channels as metabolic sensors: Studies of Kir6.x null mice
    • DOI 10.2337/diabetes.53.suppl-3.S176
    • Minami K, Miki T, Kadowaki T, Seino S: Roles of ATP-sensitive K+ channels as metabolic sensors: studies of Kir6.x null mice. Diabetes 2004;53(suppl 3):S176-S180. (Pubitemid 39564541)
    • (2004) Diabetes , vol.53 , Issue.SUPPL. 3
    • Minami, K.1    Miki, T.2    Kadowaki, T.3    Seino, S.4
  • 3
    • 0032788372 scopus 로고    scopus 로고
    • Molecular biology of adenosine triphosphate-sensitive potassium channels
    • DOI 10.1210/er.20.2.101
    • Aguilar-Bryan L, Bryan J: Molecular biology of adenosine triphosphate-sensitive potassium channels. Endocr Rev 1999;20:101-135. (Pubitemid 29339588)
    • (1999) Endocrine Reviews , vol.20 , Issue.2 , pp. 101-135
    • Aguilar-Bryan, L.1    Bryan, J.2
  • 5
    • 0035823614 scopus 로고    scopus 로고
    • Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain
    • Bajgar R, Seetharaman S, Kowaltowski AJ, Garlid KD, Paucek P: Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain. J Biol Chem 2001;276:33369-33374.
    • (2001) J Biol Chem , vol.276 , pp. 33369-33374
    • Bajgar, R.1    Seetharaman, S.2    Kowaltowski, A.J.3    Garlid, K.D.4    Paucek, P.5
  • 6
    • 0025913049 scopus 로고
    • + channel in the mitochondrial inner membrane
    • Inoue I, Nagase H, Kishi K, Higuti T: ATP-sensitive K+ channel in the mitochondrial inner membrane. Nature 1991;352:244-247. (Pubitemid 21912326)
    • (1991) Nature , vol.352 , Issue.6332 , pp. 244-247
    • Inoue, I.1    Nagase, H.2    Kishi, K.3    Higuti, T.4
  • 7
    • 0030667765 scopus 로고    scopus 로고
    • Intracellular targets for antidiabetic sulfonylureas and potassium channel openers
    • Szewczyk A: Intracellular targets for antidiabetic sulfonylureas and potassium channel openers. Biochem Pharmacol 1997;54:961-965.
    • (1997) Biochem Pharmacol , vol.54 , pp. 961-965
    • Szewczyk, A.1
  • 8
    • 0015151874 scopus 로고
    • Intravenous diazoxide for severe hypertension in childhood
    • McLaine PN, Drummond KN: Intravenous diazoxide for severe hypertension in childhood. J Pediatr 1971;79:829-832.
    • (1971) J Pediatr , vol.79 , pp. 829-832
    • McLaine, P.N.1    Drummond, K.N.2
  • 9
    • 0038729527 scopus 로고    scopus 로고
    • Levosimendan: A new dual-action drug in the treatment of acute heart failure
    • Mebazaa A, Erhardt L: Levosimendan: a new dual-action drug in the treatment of acute heart failure. Int J Clin Pract 2003;57:410-416. (Pubitemid 36805573)
    • (2003) International Journal of Clinical Practice , vol.57 , Issue.5 , pp. 410-416
    • Mebazaa, A.1    Erhardt, L.2
  • 10
    • 0033841427 scopus 로고    scopus 로고
    • Do mitochondrial K(ATP) channels serve as triggers rather than end-effectors of ischemic preconditioning's protection?
    • Downey JM, Cohen MV: Do mitochondrial K(ATP) channels serve as triggers rather than end-effectors of ischemic preconditioning's protection? Basic Res Cardiol 2000;95:272-274.
    • (2000) Basic Res Cardiol , vol.95 , pp. 272-274
    • Downey, J.M.1    Cohen, M.V.2
  • 11
    • 28044469874 scopus 로고    scopus 로고
    • K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons
    • DOI 10.1038/nn1570, PII N1570
    • Liss B, Haeckel O, Wildmann J, Miki T, Seino S, Roeper J: K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons. Nat Neurosci 2005;8:1742-1751. (Pubitemid 41683203)
    • (2005) Nature Neuroscience , vol.8 , Issue.12 , pp. 1742-1751
    • Liss, B.1    Haeckel, O.2    Wildmann, J.3    Miki, T.4    Seino, S.5    Roeper, J.6
  • 14
    • 34548700630 scopus 로고    scopus 로고
    • Infantile spasms as an epileptic feature of DEND syndrome associated with an activating mutation in the potassium adenosine triphosphate (ATP) channel, Kir6.2
    • DOI 10.1177/0883073807306272
    • Bahi-Buisson N, Eisermann M, Nivot S, Bellanne-Chantelot C, Dulac O, Bach N, et al: Infantile spasms as an epileptic feature of DEND syndrome associated with an activating mutation in the potassium adenosine triphosphate (ATP) channel, Kir6.2. J Child Neurol 2007;22:1147-1150. (Pubitemid 47412694)
    • (2007) Journal of Child Neurology , vol.22 , Issue.9 , pp. 1147-1150
    • Bahi-Buisson, N.1    Eisermann, M.2    Nivot, S.3    Bellanne-Chantelot, C.4    Dulac, O.5    Bach, N.6    Plouin, P.7    Chiron, C.8    De Lonlay, P.9
  • 15
    • 4344571432 scopus 로고    scopus 로고
    • ATP channel subunits in the hippocampus of rats subjected to picrotoxin-induced kindling
    • DOI 10.1016/j.molbrainres.2004.06.005, PII S0169328X04002670
    • Jiang K, Shui Q, Xia Z, Yu Z: Changes in the gene and protein expression of K(ATP) channel subunits in the hippocampus of rats subjected to picrotoxin-induced kindling. Brain Res Mol Brain Res 2004;128:83-89. (Pubitemid 39158883)
    • (2004) Molecular Brain Research , vol.128 , Issue.1 , pp. 83-89
    • Jiang, K.1    Shui, Q.2    Xia, Z.3    Yu, Z.4
  • 16
    • 5644253167 scopus 로고    scopus 로고
    • Effect of diazoxide on regulation of vesicular and plasma membrane GABA transporter genes and proteins in hippocampus of rats subjected to picrotoxin-induced kindling
    • DOI 10.1016/j.neures.2004.08.001, PII S0168010204002020
    • Jiang KW, Gao F, Shui QX, Yu ZS, Xia ZZ: Effect of diazoxide on regulation of vesicular and plasma membrane GABA transporter genes and proteins in hippocampus of rats subjected to picrotoxin-induced kindling. Neurosci Res 2004;50:319-329. (Pubitemid 39370899)
    • (2004) Neuroscience Research , vol.50 , Issue.3 , pp. 319-329
    • Jiang, K.-W.1    Gao, F.2    Shui, Q.-X.3    Yu, Z.-S.4    Xia, Z.-Z.5
  • 19
    • 0035947177 scopus 로고    scopus 로고
    • Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure
    • DOI 10.1126/science.1059829
    • Yamada K, Ji JJ, Yuan H, Miki T, Sato S, Horimoto N, et al: Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure. Science 2001;292:1543-1546. (Pubitemid 32493422)
    • (2001) Science , vol.292 , Issue.5521 , pp. 1543-1546
    • Yamada, K.1    Juan, J.J.2    Yuan, H.3    Miki, T.4    Sato, S.5    Horimoto, N.6    Shimizu, T.7    Seino, S.8    Inagaki, N.9
  • 20
    • 65949090732 scopus 로고    scopus 로고
    • Iptakalim ameliorates MPP+-induced astrocyte mitochondrial dysfunction by increasing mitochondrial complex activity besides opening mitoK(ATP) channels
    • Zhang S, Ding JH, Zhou F, Wang ZY, Zhou XQ, Hu G: Iptakalim ameliorates MPP+-induced astrocyte mitochondrial dysfunction by increasing mitochondrial complex activity besides opening mitoK(ATP) channels. J Neurosci Res 2009;87:1230-1239.
    • (2009) J Neurosci Res , vol.87 , pp. 1230-1239
    • Zhang, S.1    Ding, J.H.2    Zhou, F.3    Wang, Z.Y.4    Zhou, X.Q.5    Hu, G.6
  • 21
    • 65449118394 scopus 로고    scopus 로고
    • KR-31761, a novel K+(ATP)-channel opener, exerts cardioprotective effects by opening both mitochondrial K+(ATP) and sarcolemmal K+(ATP) channels in rat models of ischemia/reperfusion-induced heart injury
    • Yang MK, Lee SH, Seo HW, Yi KY, Yoo SE, Lee BH, et al: KR-31761, a novel K+(ATP)-channel opener, exerts cardioprotective effects by opening both mitochondrial K+(ATP) and sarcolemmal K+(ATP) channels in rat models of ischemia/reperfusion-induced heart injury. J Pharmacol Sci 2009;109:222-232.
    • (2009) J Pharmacol Sci , vol.109 , pp. 222-232
    • Yang, M.K.1    Lee, S.H.2    Seo, H.W.3    Yi, K.Y.4    Yoo, S.E.5    Lee, B.H.6
  • 22
    • 54049142448 scopus 로고    scopus 로고
    • Opening of microglial K(ATP) channels inhibits rotenone-induced neuroinflammation
    • Zhou F, Yao HH, Wu JY, Ding JH, Sun T, Hu G: Opening of microglial K(ATP) channels inhibits rotenone-induced neuroinflammation. J Cell Mol Med 2008;12:1559-1570.
    • (2008) J Cell Mol Med , vol.12 , pp. 1559-1570
    • Zhou, F.1    Yao, H.H.2    Wu, J.Y.3    Ding, J.H.4    Sun, T.5    Hu, G.6
  • 23
    • 42049097234 scopus 로고    scopus 로고
    • ATP channel openers facilitate glutamate uptake by GluTs in rat primary cultured astrocytes
    • DOI 10.1038/sj.npp.1301501, PII 1301501
    • Sun XL, Zeng XN, Zhou F, Dai CP, Ding JH, Hu G: KATP channel openers facilitate glutamate uptake by GluTs in rat primary cultured astrocytes. Neuropsychopharmacology 2008;33:1336-1342. (Pubitemid 351521709)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.6 , pp. 1336-1342
    • Sun, X.-L.1    Zeng, X.-N.2    Zhou, F.3    Dai, C.-P.4    Ding, J.-H.5    Hu, G.6
  • 24
    • 33745003688 scopus 로고    scopus 로고
    • The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus
    • DOI 10.1523/JNEUROSCI.0037-06.2006
    • Wallraff A, Kohling R, Heinemann U, Theis M, Willecke K, Steinhauser C: The impact of astrocytic gap junctional coupling on potassium buffering in the hippocampus. J Neurosci 2006;26:5438-5447. (Pubitemid 44318396)
    • (2006) Journal of Neuroscience , vol.26 , Issue.20 , pp. 5438-5447
    • Wallraff, A.1    Kohling, R.2    Heinemann, U.3    Theis, M.4    Willecke, K.5    Steinhauser, C.6
  • 25
    • 33644519960 scopus 로고    scopus 로고
    • Astrocyte dysfunction in neurological disorders: A molecular perspective
    • DOI 10.1038/nrn1870, PII N1870
    • Seifert G, Schilling K, Steinhauser C: Astrocyte dysfunction in neurological disorders: a molecular perspective. Nat Rev Neurosci 2006;7:194-206. (Pubitemid 43292465)
    • (2006) Nature Reviews Neuroscience , vol.7 , Issue.3 , pp. 194-206
    • Seifert, G.1    Schilling, K.2    Steinhauser, C.3
  • 26
    • 0034953204 scopus 로고    scopus 로고
    • Mechanisms of spreading depression and hypoxic spreading depression-like depolarization
    • Somjen GG: Mechanisms of spreading depression and hypoxic spreading depression-like depolarization. Physiol Rev 2001;81:1065-1096.
    • (2001) Physiol Rev , vol.81 , pp. 1065-1096
    • Somjen, G.G.1
  • 27
    • 0028293560 scopus 로고
    • Extracellular ATP-induced currents in astrocytes: Involvement of a cation channel
    • Walz W, Gimpl G, Ohlemeyer C, Kettenmann H: Extracellular ATP-induced currents in astrocytes:involvement of a cation channel. J Neurosci Res 1994;38:12-18. (Pubitemid 24143179)
    • (1994) Journal of Neuroscience Research , vol.38 , Issue.1 , pp. 12-18
    • Walz, W.1    Gimpl, G.2    Ohlemeyer, C.3    Kettenmann, H.4
  • 28
    • 0013926565 scopus 로고
    • Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia
    • Orkand RK, Nicholls JG, Kuffler SW: Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia. J Neurophysiol 1966;29:788-806.
    • (1966) J Neurophysiol , vol.29 , pp. 788-806
    • Orkand, R.K.1    Nicholls, J.G.2    Kuffler, S.W.3
  • 29
    • 75649085339 scopus 로고    scopus 로고
    • Firing patterns and synchronization in nonsynaptic epileptiform activity: The effect of gap junctions modulated by potassium accumulation
    • Santos DO, Rodrigues AM, de Almeida AC, Dickman R: Firing patterns and synchronization in nonsynaptic epileptiform activity: the effect of gap junctions modulated by potassium accumulation. Phys Biol 2009;6:46019.
    • (2009) Phys Biol , vol.6 , pp. 46019
    • Santos, D.O.1    Rodrigues, A.M.2    De Almeida, A.C.3    Dickman, R.4
  • 30
    • 33644965839 scopus 로고    scopus 로고
    • Functional contribution of specific brain areas to absence seizures: Role of thalamic gap-junctional coupling
    • Proulx E, Leshchenko Y, Kokarovtseva L, Khokhotva V, El-Beheiry M, Snead OC, 3rd, et al: Functional contribution of specific brain areas to absence seizures:role of thalamic gap-junctional coupling. Eur J Neurosci 2006;23:489-496.
    • (2006) Eur J Neurosci , vol.23 , pp. 489-496
    • Proulx, E.1    Leshchenko, Y.2    Kokarovtseva, L.3    Khokhotva, V.4    El-Beheiry, M.5    Snead III, O.C.6
  • 31
    • 0031148970 scopus 로고    scopus 로고
    • Asymmetric gap junctional coupling between glial cells in the rat retina
    • DOI 10.1002/(SICI)1098-1136(199705)20:1<10::AID-GLIA2>3.0.CO;2-9
    • Zahs KR, Newman EA: Asymmetric gap junctional coupling between glial cells in the rat retina. Glia 1997;20:10-22. (Pubitemid 27207004)
    • (1997) GLIA , vol.20 , Issue.1 , pp. 10-22
    • Zahs, K.R.1    Newman, E.A.2
  • 32
    • 45549101476 scopus 로고    scopus 로고
    • Isolation and purification of primary rodent astrocytes
    • Chapter 3:Unit 3.5
    • Weinstein DE: Isolation and purification of primary rodent astrocytes. Curr Protoc Neurosci 2001;Chapter 3:Unit 3.5.
    • (2001) Curr Protoc Neurosci
    • Weinstein, D.E.1
  • 33
    • 0034717542 scopus 로고    scopus 로고
    • Activity-dependent Neuronal Control of gap-junctional Communication in astrocytes
    • DOI 10.1083/jcb.149.7.1513
    • Rouach N, Glowinski J, Giaume C: Activity-dependent neuronal control of gap-junctional communication in astrocytes. J Cell Biol 2000;149:1513-1526. (Pubitemid 30437623)
    • (2000) Journal of Cell Biology , vol.149 , Issue.7 , pp. 1513-1526
    • Rouach, N.1    Glowinski, J.2    Giaume, C.3
  • 34
    • 12344257722 scopus 로고    scopus 로고
    • Activation of ATP-sensitive potassium channels prevents the cleavage of cytosolic mu-calpain and abrogates the elevation of nuclear c-Fos and c-Jun expressions after hypoxic-ischemia in neonatal rat brain
    • Jiang KW, Yu ZS, Shui QX, Xia ZZ: Activation of ATP-sensitive potassium channels prevents the cleavage of cytosolic mu-calpain and abrogates the elevation of nuclear c-Fos and c-Jun expressions after hypoxic-ischemia in neonatal rat brain. Brain Res Mol Brain Res 2005;133:87-94.
    • (2005) Brain Res Mol Brain Res , vol.133 , pp. 87-94
    • Jiang, K.W.1    Yu, Z.S.2    Shui, Q.X.3    Xia, Z.Z.4
  • 35
    • 0015306389 scopus 로고
    • Modification of seizure activity by electrical stimulation. I. After-discharge threshold
    • Racine RJ: Modification of seizure activity by electrical stimulation. I. After-discharge threshold. Electroencephalogr Clin Neurophysiol 1972;32:269-279.
    • (1972) Electroencephalogr Clin Neurophysiol , vol.32 , pp. 269-279
    • Racine, R.J.1
  • 37
    • 0028574814 scopus 로고
    • Potassium channel activators counteract anoxic hyperexcitability but not 4-aminopyridine-induced epileptiform activity in the rat hippocampal slice
    • Mattia D, Nagao T, Rogawski MA, Avoli M: Potassium channel activators counteract anoxic hyperexcitability but not 4-aminopyridine-induced epileptiform activity in the rat hippocampal slice. Neuropharmacology 1994;33:1515-1522.
    • (1994) Neuropharmacology , vol.33 , pp. 1515-1522
    • Mattia, D.1    Nagao, T.2    Rogawski, M.A.3    Avoli, M.4
  • 38
    • 0025316950 scopus 로고
    • Purification and reconstitution of the sodium- and potassium-coupled glutamate transport glycoprotein from rat brain
    • DOI 10.1021/bi00480a025
    • Danbolt NC, Pines G, Kanner BI: Purification and reconstitution of the sodium- and potassium-coupled glutamate transport glycoprotein from rat brain. Biochemistry 1990;29:6734-6740. (Pubitemid 20223571)
    • (1990) Biochemistry , vol.29 , Issue.28 , pp. 6734-6740
    • Danbolt, N.C.1    Pines, G.2    Kanner, B.I.3
  • 39
    • 23044435896 scopus 로고    scopus 로고
    • Astrocytes, from brain glue to communication elements: The revolution continues
    • DOI 10.1038/nrn1722
    • Volterra A, Meldolesi J: Astrocytes, from brain glue to communication elements:the revolution continues. Nat Rev Neurosci 2005;6:626-640. (Pubitemid 41059337)
    • (2005) Nature Reviews Neuroscience , vol.6 , Issue.8 , pp. 626-640
    • Volterra, A.1    Meldolesi, J.2
  • 40
    • 0033673938 scopus 로고    scopus 로고
    • Developmental downregulation of ATP-sensitive potassium conductance in astrocytes in situ
    • Brockhaus J, Deitmer JW: Developmental downregulation of ATP-sensitive potassium conductance in astrocytes in situ. Glia 2000;32:205-213.
    • (2000) Glia , vol.32 , pp. 205-213
    • Brockhaus, J.1    Deitmer, J.W.2
  • 41
    • 0037198553 scopus 로고    scopus 로고
    • +-channel, Kir6.2, in rat brain neurons and glial cells
    • DOI 10.1016/S0169-328X(02)00137-7, PII S0169328X02001377
    • Zhou M, Tanaka O, Suzuki M, Sekiguchi M, Takata K, Kawahara K, et al: Localization of pore-forming subunit of the ATP-sensitive K(+)-channel, Kir6.2, in rat brain neurons and glial cells. Brain Res Mol Brain Res 2002;101:23-32. (Pubitemid 34465557)
    • (2002) Molecular Brain Research , vol.101 , Issue.1-2 , pp. 23-32
    • Zhou, M.1    Tanaka, O.2    Suzuki, M.3    Sekiguchi, M.4    Takata, K.5    Kawahara, K.6    Abe, H.7
  • 42
    • 0141456728 scopus 로고    scopus 로고
    • Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain
    • Chen M, Dong Y, Simard JM: Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain. J Neurosci 2003;23:8568-8577. (Pubitemid 37158756)
    • (2003) Journal of Neuroscience , vol.23 , Issue.24 , pp. 8568-8577
    • Chen, M.1    Dong, Y.2    Simard, J.M.3
  • 43
    • 0032807906 scopus 로고    scopus 로고
    • Mitochondrial ATP-dependent potassium channels. Viable candidate effectors of ischemic preconditioning
    • Liu Y, Sato T, Seharaseyon J, Szewczyk A, O'Rourke B, Marban E: Mitochondrial ATP-dependent potassium channels. Viable candidate effectors of ischemic preconditioning. Ann N Y Acad Sci 1999;874:27-37.
    • (1999) Ann N Y Acad Sci , vol.874 , pp. 27-37
    • Liu, Y.1    Sato, T.2    Seharaseyon, J.3    Szewczyk, A.4    O'Rourke, B.5    Marban, E.6
  • 45
    • 0033968088 scopus 로고    scopus 로고
    • 2+-independent mechanism
    • Velasco A, Tabernero A, Granda B, Medina JM: ATP-sensitive potassium channel regulates astrocytic gap junction permeability by a Ca2+-independent mechanism. J Neurochem 2000;74:1249-1256. (Pubitemid 30104323)
    • (2000) Journal of Neurochemistry , vol.74 , Issue.3 , pp. 1249-1256
    • Velasco, A.1    Tabernero, A.2    Granda, B.3    Medina, J.M.4
  • 46
    • 41349099062 scopus 로고    scopus 로고
    • KATP channel openers have opposite effects on mitochondrial respiration under different energetic conditions
    • Riess ML, Camara AK, Heinen A, Eells JT, Henry MM, Stowe DF: KATP channel openers have opposite effects on mitochondrial respiration under different energetic conditions. J Cardiovasc Pharmacol 2008;51:483-491.
    • (2008) J Cardiovasc Pharmacol , vol.51 , pp. 483-491
    • Riess, M.L.1    Camara, A.K.2    Heinen, A.3    Eells, J.T.4    Henry, M.M.5    Stowe, D.F.6
  • 48
    • 23644442552 scopus 로고    scopus 로고
    • ATP-sensitive potassium channelopathies: Focus on insulin secretion
    • Ashcroft FM: ATP-sensitive potassium channelopathies:focus on insulin secretion. J Clin Invest 2005;115:2047-2058.
    • (2005) J Clin Invest , vol.115 , pp. 2047-2058
    • Ashcroft, F.M.1
  • 49
    • 0037341012 scopus 로고    scopus 로고
    • Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death
    • DOI 10.1046/j.1471-4159.2003.01625.x
    • Tai KK, McCrossan ZA, Abbott GW: Activation of mitochondrial ATP-sensitive potassium channels increases cell viability against rotenone-induced cell death. J Neurochem 2003;84:1193-200. (Pubitemid 36330671)
    • (2003) Journal of Neurochemistry , vol.84 , Issue.5 , pp. 1193-1200
    • Tai, K.-K.1    McCrossan, Z.A.2    Abbott, G.W.3
  • 50
    • 9644253068 scopus 로고    scopus 로고
    • Targeting mitochondrial ATP-sensitive potassium channels - A novel approach to neuroprotection
    • DOI 10.1016/j.brainresrev.2004.06.011, PII S0165017304000839
    • Busija DW, Lacza Z, Rajapakse N, Shimizu K, Kis B, Bari F, et al: Targeting mitochondrial ATP-sensitive potassium channels - a novel approach to neuroprotection. Brain Res Brain Res Rev 2004;46:282-294. (Pubitemid 39574329)
    • (2004) Brain Research Reviews , vol.46 , Issue.3 , pp. 282-294
    • Busija, D.W.1    Lacza, Z.2    Rajapakse, N.3    Shimizu, K.4    Kis, B.5    Bari, F.6    Domoki, F.7    Horiguchi, T.8
  • 51
    • 42149112453 scopus 로고    scopus 로고
    • Astrocytes in the Epileptic Brain
    • DOI 10.1016/j.neuron.2008.04.002, PII S0896627308003061
    • Wetherington J, Serrano G, Dingledine R: Astrocytes in the epileptic brain. Neuron 2008;58:168-178. (Pubitemid 351539007)
    • (2008) Neuron , vol.58 , Issue.2 , pp. 168-178
    • Wetherington, J.1    Serrano, G.2    Dingledine, R.3
  • 53
    • 0034638489 scopus 로고    scopus 로고
    • Carbenoxolone depresses spontaneous epileptiform activity in the CA1 region of rat hippocampal slices
    • Ross FM, Gwyn P, Spanswick D, Davies SN: Carbenoxolone depresses spontaneous epileptiform activity in the CA1 region of rat hippocampal slices. Neuroscience 2000;100:789-796.
    • (2000) Neuroscience , vol.100 , pp. 789-796
    • Ross, F.M.1    Gwyn, P.2    Spanswick, D.3    Davies, S.N.4
  • 54
    • 0036498359 scopus 로고    scopus 로고
    • Upregulation in astrocytic connexin 43 gap junction levels may exacerbate generalized seizures in mesial temporal lobe epilepsy
    • DOI 10.1016/S0006-8993(01)03289-9, PII S0006899301032899
    • Fonseca CG, Green CR, Nicholson LF: Upregulation in astrocytic connexin 43 gap junction levels may exacerbate generalized seizures in mesial temporal lobe epilepsy. Brain Res 2002;929:105-16. (Pubitemid 34164415)
    • (2002) Brain Research , vol.929 , Issue.1 , pp. 105-116
    • Fonseca, C.G.1    Green, C.R.2    Nicholson, L.F.B.3
  • 55
    • 11144271430 scopus 로고    scopus 로고
    • Emerging role of gap junctions in epilepsy
    • Nemani VM, Binder DK: Emerging role of gap junctions in epilepsy. Histol Histopathol 2005;20:253-259. (Pubitemid 40029003)
    • (2005) Histology and Histopathology , vol.20 , Issue.1 , pp. 253-259
    • Nemani, V.M.1    Binder, D.K.2
  • 56
    • 2942614082 scopus 로고    scopus 로고
    • Update on connexins and gap junctions in neurons and glia in the mammalian nervous system
    • DOI 10.1016/j.brainresrev.2004.05.005, PII S0165017304000694, Chemical and Electrical Synapses
    • Nagy JI, Dudek FE, Rash JE: Update on connexins and gap junctions in neurons and glia in the mammalian nervous system. Brain Res Brain Res Rev 2004;47:191-215. (Pubitemid 39574320)
    • (2004) Brain Research Reviews , vol.47 , Issue.1-3 , pp. 191-215
    • Nagy, J.I.1    Dudek, F.E.2    Rash, J.E.3
  • 58
    • 0035944942 scopus 로고    scopus 로고
    • Connexin26 in adult rodent central nervous system: Demonstration at astrocytic gap junctions and colocalization with connexin30 and connexin43
    • DOI 10.1002/cne.1414
    • Nagy JI, Li X, Rempel J, Stelmack G, Patel D, Staines WA, et al: Connexin26 in adult rodent central nervous system:demonstration at astrocytic gap junctions and colocalization with connexin30 and connexin43. J Comp Neurol 2001;441:302-323. (Pubitemid 33104407)
    • (2001) Journal of Comparative Neurology , vol.441 , Issue.4 , pp. 302-323
    • Nagy, J.I.1    Li, X.2    Rempel, J.3    Stelmack, G.4    Patel, D.5    Staines, W.A.6    Yasumura, T.7    Rash, J.E.8
  • 60
    • 51349116146 scopus 로고    scopus 로고
    • Neurons control the expression of connexin 30 and connexin 43 in mouse cortical astrocytes
    • Koulakoff A, Ezan P, Giaume C: Neurons control the expression of connexin 30 and connexin 43 in mouse cortical astrocytes. Glia 2008;56:1299-1311.
    • (2008) Glia , vol.56 , pp. 1299-1311
    • Koulakoff, A.1    Ezan, P.2    Giaume, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.