Functional contribution of specific brain areas to absence seizures: Role of thalamic gap-junctional coupling

European Journal of Neuroscience

Volumn 23, Issue 2, 2006, Pages 489-496

  Proulx, Éliane ^a   Leshchenko, Yevgen ^a   Kokarovtseva, Larisa ^a   Khokhotva, Vladislav ^a   El Beheiry, Mostafa ^a   Snead III, O Carter ^a,b   Perez Velazquez, Jose L ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Epilepsy; Gap junctions; In vivo recordings; Rats; Seizures; Synchrony; Thalamus

Indexed keywords

18ALPHA GLYCYRRHETINIC ACID; CARBENOXOLONE; GLYCYRRHIZIC ACID DERIVATIVE; SALINAZID; TRIMETHYLAMINE;

ABSENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; DISEASE DURATION; DRUG DELIVERY SYSTEM; ELECTRIC POTENTIAL; ELECTRODE; GAP JUNCTION; HIPPOCAMPUS; LIMBIC CORTEX; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; RAT; RODENT; SYNAPTIC TRANSMISSION; THALAMUS;

ANIMALS; ANIMALS, NEWBORN; BRAIN MAPPING; CARBENOXOLONE; DISEASE MODELS, ANIMAL; ELECTRODES; ELECTROENCEPHALOGRAPHY; EPILEPSY, ABSENCE; EVOKED POTENTIALS; FUNCTIONAL LATERALITY; GAP JUNCTIONS; METHYLAMINES; RATS; RATS, LONG-EVANS; SPECTRUM ANALYSIS; THALAMUS; TIME FACTORS; TRANS-1,4-BIS(2-CHLOROBENZAMINOMETHYL)CYCLOHEXANE DIHYDROCHLORIDE;

EID: 33644965839     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2005.04558.x     Document Type: Article

References (59)

1. Amzica F. 2002 Physiology of sleep and wakefulness as it relates to the physiology of epilepsy JClinNeurophysiol 19 488 503
2. Amzica F. Steriade M. 2000 Neuronal and glial membrane potentials during sleep and paroxysmal oscillations in the neocortex JNeurosci 20 6648 6665
3. Chan KF. Jia Z. Murphy PA. Burnham WM. Cortez MA. Snead OC. 2004 Learning and memory impairment in rats with chronic atypical absence seizures ExpNeurol 190 328 336
4. + channel in cultured rat hippocampal neurones JPhysiol(Lond) 511 119 132
5. Condorelli DF. Trovato-Salinaro A. Mudo G. Mirone MB. Belluardo N. 2003 Cellular expression of connexins in the rat brain: neuronal localization, effects of kainate-induced seizures and expression in apoptotic neuronal cells EurJNeurosci 18 1807 1827
6. Cortez MA. McKerlie C. Snead OC. 2001 A model of atypical absence seizures: EEG, pharmacology, and developmental characterization Neurology 56 341 349
7. Cortez MA. Shukla S. Bercovici E. Serbanescu I. Mistry N. Snead OC. III. 2002 Chronobiological variation of spike-and-wave discharge duration (SWD) in the rat AY-9944 rat model of atypical absence seizures Epilepsia 43 Suppl. 7 41
8. B receptors in excitation and inhibition of thalamocortical cells Trends Neurosci 14 16 21
9. Davidson JS. Baumgarten JM. 1988 Glycyrrhetinic acid derivatives: a novel class of inhibitors of gap junctional intercellular communication. Structure-activity relationship JPharmacolExpTher 246 1104 1107
10. De Curtis M. Manfridi A. Biella G. 1998 Activity-dependent pH shifts and periodic recurrence of spontaneous interictal spikes in a model of focal epileptogenesis JNeurosci 18 7543 7551
11. Delanty N. French J. 1999 Treatment of Lennox-Gastaut syndrome CNS Drugs 10 181 190
12. Draguhn A. Traub RD. Schmitz D. Jefferys JG. 1998 Electrical coupling underlies high frequency oscillations in the hippocampus in vitro Nature 394 189 192
13. Frantseva MV. Kokarovtseva L. Naus CCG. Carlen PL. Perez Velazquez JL. 2002a Specific gap junctions enhance the neuronal vulnerability to brain traumatic injury JNeurosci 22 644 653
14. Frantseva MV. Kokarovtseva L. Perez Velazquez JL. 2002b Ischemia-induced brain damage depends on specific gap junctional coupling JCerebBlood Flow Metab 22 453 462
15. Fuentealba P. Crochet S. Timofeev I. Bazhenov M. Sejnowski TJ. Steriade M. 2004 Experimental evidence and modeling studies support a synchronizing role for electrical coupling in the cat thalamic reticular neurons in vivo EurJNeurosci 20 111 119
16. Funder JW. 1996 Mineralocorticoid receptors in the central nervous system JSteroidBiochemMolecBiol 56 179 183
17. Gajda Z. Gyengesi E. Hermesz E. Said Ali K. Szente M. 2003 Involvement of gap junctions in the manifestation and control of the duration of seizures in rats in vivo Epilepsia 44 1596 1600
18. Gareri P. Condorelli D. Belluardo N. Russo E. Loiacono A. Barresi V. Trovato-Salinato A. Mirone MB. Ibbadu GF. de Sarro G. 2004 Anticonvulsant effects of carbenoxolone in genetically epilepsy prone rats (GEPRs) Neuropharmacology 47 1205 1216
19. Gastaut H. Zifkin BG. 1988 Secondary bilateral synchrony and Lennox-Gastaut syndrome. The Lennox-Gastaut Syndrome Liss New York, pp. 221 242 q27
20. Giuliano A. De Curtis M. Panzica F. Spreafico R. 1989 Intrinsic properties of nucleus reticularis thalami neurons of the rat studied in vitro JPhysiol(Lond) 416 111 122
21. Gloor P. Fariello RG. 1988 Generalized epilepsy: some of its cellular mechanisms differ from those of focal epilepsy Trends Neurosci 11 63 68
22. Goodenough DA. Musil LS. 1993 Gap junctions and tissue business: problems and strategies for developing specific functional reagents JCell Sci 17 133 138
23. Herman JP. Watson SJ. Chao HM. Coirini H. McEwen BS. 1993 Diurnal regulation of glucocorticoid receptor and mineralocorticoid receptor mRNAs in rat hippocampus MolCellNeurosci 4 181 190
24. Hosseinzadeh H. Asl MN. 2003 Anticonvulsant, sedative and muscle relaxant effects of carbenoxolone in mice BMC Pharmacol 3 3
25. Hughes SW. Blethyn KL. Cope DW. Crunelli V. 2002 Properties and origin of spikelets in thalamocortical neurones in vitro Neuroscience 110 395 401
26. Inoue M. Duysens J. Vossen JMH. Coenen AML. 1993 Thalamic multiple-unit activity underlying spike-wave discharges in anaesthetized rats Brain Res 612 35 40
27. Jasper HH. Droogleever-Fortuyn J. 1947 Experimental studies on the functional anatomy of petit mal epilepsy ResPubAssocResNervMentDis 26 272 298
28. Joels M. 1997 Steroid hormones and excitability in the mammalian brain FrontNeuroendocrinol 18 2 48
29. Kelly T. Church J. 2005 The weak bases NH (3) and trimethylamine inhibit the medium and slow afterhyperpolarizations in rat CA1 pyramidal neurons Pflugers Arch 20 162 166
30. Kiehn O. Tresch MC. 2002 Gap junctions and motor behavior Trends Neurosci 25 108 115
31. Krewson CE. Klarman ML. Saltzman WM. 1995 Distribution of nerve growth factor following direct delivery to brain interstitium Brain Res 680 196 206
32. Landisman CE. Long MA. Beirerlein M. Deans MR. Paul DL. Connors BW. 2002 Electrical synapses in the thalamic reticular nucleus JNeurosci 22 1002 1009
33. Long MA. Landisman CE. Connors BW. 2004 Small clusters of electrically coupled neurons generate synchronous rhythms in the thalamic reticular nucleus JNeurosci 14 341 349
34. Magarinos-Ascone C. Pazo JH. Macadar O. Buno W. 2002 High-frequency stimulation of the subthalamic neurons: a possible cellular mechanism in parkinson's disease Neuroscience 115 1109 1117
35. Manning J-PA. Richards DA. Bowery NG. 2003 Pharmacology of absence epilepsy Trends PharmacolSci 24 542 549
36. Mares P. Maresova D. Trojan S. Fischer J. 1982 Ontogenetic development of rhythmic thalamo-cortical phenomena in the rat Brain ResBull 8 765 769
37. Meeren HKM. Pijn JPM. Van Luijtelaar ELJM. Coenen AML. Lopes da Silva FH. 2002 Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats JNeurosci 22 1480 1495
38. Munsch T. Pape HC. 1999 Modulation of the hyperpolarization-activated cation current of rat thalamic relay neurons by intracellular pH JPhysiol(Lond) 519 493 504
39. Nyikos L. Lasztoczi B. Antal K. Kovacs R. Kardos J. 2003 Desynchronization of spontaneously recurrent experimental seizures proceeds with a single rhythm Neuroscience 121 705 717
40. Osborne PB. Williams JT. 1996 Forskolin enhancement of opioid currents in rat locus coeruleus neurons JNeurophysiol 76 1559 1565
41. Paxinos G. Watson C. 1986 The Rat Brain in Stereotaxic Coordinates Academic Press Sydney
42. Perez Velazquez JL. Carlen PL. 2000 Gap junctions, synchrony and seizures Trends Neurosci 23 68 74
43. Perez Velazquez JL. Valiante TA. Carlen PL. 1994 Modulation of gap junctional mechanisms during calcium-free induced field burst activity: a possible role for electrotonic coupling in epileptogenesis JNeurosci 14 4308 4317
44. Ross FM. Gwyn P. Spanswick D. Davies SN. 2000 Carbenoxolone depresses spontaneous epileptiform activity in the CA1 region of rat hippocampal slices Neuroscience 100 789 796
45. Rouach N. Segal M. Koulakoff A. Giaume C. Avignone E. 2003 Carbenoxolone blockade of neuronal network activity in culture is not mediated by an action on gap junctions JPhysiol(Lond) 553 729 745
46. Rozental R. Srinivas M. Spray DC. 2001 How to close a gap junction channel. In Bruzzone R. Guiaume C. (Eds) Methods in Molecular Biology Vol. 154 Connexin Methods and Protocols. Humana Press Inc. Totowa, NJ, pp. 447 476 q29
47. Schmitz D. Schuchmann S. Fisahn A. Draguhn A. Buhl EH. Petrasch-Parwez RE. Dermietzel R. Heinemann U. Traub RD. 2001 Axo-axonal coupling: a novel mechanism for ultrafast neuronal communication Neuron 31 831 840
48. Seidenbrecher T. Pape HC. 2001 Contribution of intralaminar thalamic nuclei to spike-and-wave-discharges during spontaneous seizures in a genetic rat model of absence epilepsy EurJNeurosci 13 1537 1546
49. Seidenbrecher T. Staak R. Pape HC. 1998 Relations between cortical and thalamic cellular activities during absence seizures in rats EurJNeurosci 10 1103 1112
50. Smith KA. Bierkamper GG. 1990 Paradoxical role of GABA in a chronic model of petit mal (absence)-like epilepsy in the rat EurJPharmacol 176 45 55
51. Snead OC. 1988 The γ-hydroxybutyrate model of generalized absence seizures: further characterization and comparison to other absence models Epilepsia 29 361 368 q30
52. Steriade M. Domich L. Oakson G. Deschenes M. 1987 The deafferented reticular thalamic nucleus generates spindle rhythmicity JNeurophysiol 57 260 273
53. Szente M. Gajda Z. Said Ali K. Hermesz E. 2002 Involvement of electrical coupling in the in vivo ictal epileptiform activity induced by 4-aminopyridine in the neocortex Neuroscience 115 1067 1078
54. Traub RD. Draguhn A. Whittington MA. Baldeweg T. Bibbig A. Buhl EH. Schmitz D. 2002 Axonal gap junctions between principal neurons: a novel source of network oscillations, and perhaps epileptogenesis RevNeurosci 13 1 30
55. Traub RD. Whittington MA. Buhl EH. LeBeau FEN. Bibbig A. Boyd S. Cross H. Baldeweg T. 2001 A possible role for gap junctions in generation of very fast EEG oscillations preceding the onset of, and perhaps initiating, seizures Epilepsia 42 153 170
56. Travagli RA. Dunwiddie TV. Williams JT. 1995 Opioid inhibition in locus coeruleus JNeurophysiol 74 519 528
57. Van Luijtelaar ELJM. Coenen AML. 1986 Two types of electrocortical paroxysms in a inbred strain of rats NeurosciLett 70 393 397
58. Vergnes M. Marescaux C. Micheletti G. Reis J. Depaulis A. 1982 Spontaneous paroxysmal electroclinical patterns in rat: a model of generalized non-convulsive epilepsy NeurosciLett 33 97 101
59. Vessey JP. Lalonde MR. Mizan HA. Welch NC. Kelly MEM. Barnes S. 2004 Carbenoxolone inhibition of voltage-gated Ca channels and synaptic transmission in the retina JNeurophysiol 92 1252 1256