Putting bioactivation reactions to work: Targeting antioxidants to mitochondria

Chemico-Biological Interactions

Volumn 192, Issue 1-2, 2011, Pages 8-13

  Anders, M W ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Oxidation; Antioxidants; Bioactivaton; Drug targeting; Mitochondria; Prodrugs

Indexed keywords

2,6 XYLENOL; 3 (1 METHYL 1H IMIDAZOL 2 YLTHIO)PROPANOATE; 3 (2 NAPHTHOXY)PROPANOATE; 3 (2,6 DIMETHYLPHENOXY)ACRYLATE; 3 (2,6 DIMETHYLPHENOXY)PROPANOATE; 3 (PHENOXY)ACRYLATE DERIVATIVE; 3 (PHENOXY)PROPANOATE; 3 [(2,6 DIMETHYLPHENOXY)METHYLTHIO]PROPANOATE; 4 OXAALKANOATE DERIVATIVE; 5 (PHENOXY)PROPANOATE; ACYL COENZYME A DEHYDROGENASE; AMINO ACID; ANTIOXIDANT; CARNITINE PALMITOYLTRANSFERASE; DRUG METABOLITE; ENOYL COENZYME A HYDRATASE; ETOMOXIR; FATTY ACID; MITOCHONDRIAL ENZYME; OMEGA (1 METHYL 1H IMIDAZOL 2 YLTHIO)ALKANOATE DERIVATIVE; OMEGA (2,6 DIMETHYLPHENOXY)ALKANOATE DERIVATIVE; OMEGA (PHENOXY)ALKANOATE DERIVATIVE; PHENOL DERIVATIVE; PRODRUG; PROPIONIC ACID DERIVATIVE; REACTIVE OXYGEN METABOLITE; THIAMAZOLE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VALPROIC ACID; XENOBIOTIC AGENT;

BIOTRANSFORMATION; CATALYSIS; CELL HYPOXIA; CELL PROTECTION; CONFERENCE PAPER; CYTOTOXICITY; DRUG ACTIVATION; DRUG STRUCTURE; DRUG TARGETING; DRUG TRANSFORMATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; FATTY ACID OXIDATION; FEASIBILITY STUDY; GRAVES DISEASE; HEART MUSCLE CELL; HUMAN; HYDROLYSIS; LIVER TOXICITY; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL TOXICITY; NEPHROTOXICITY; NONHUMAN;

ANIMALS; ANTIOXIDANTS; BIOCATALYSIS; BIOTRANSFORMATION; MITOCHONDRIA; RATS; XENOBIOTICS;

RATTUS; THIA;

EID: 79958025800     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2010.10.004     Document Type: Conference Paper

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