Effect of short term and chronic administration of Sutherlandia frutescens on pharmacokinetics of nevirapine in rats

International Journal of Pharmaceutics

Volumn 413, Issue 1-2, 2011, Pages 44-50

  Minocha, Mukul ^a   Mandava, Nanda K ^a   Kwatra, Deep ^a   Pal, Dhananjay ^a   Folk, William R ^b   Earla, Ravinder ^a   Mitra, Ashim K ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b University of Missouri   (United States)

Author keywords

CYP3A; Drug herb interaction; LS 180; Pharmacokinetics; Sutherlandia

Indexed keywords

CYTOCHROME P450 3A2; CYTOCHROME P450 3A4; MESSENGER RNA; NEVIRAPINE; PLANT EXTRACT; RIFAMPICIN; SUTHERLANDIA FRUTESCENS EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DRUG BIOAVAILABILITY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MALE; MEDICINAL PLANT; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; RNA TRANSLATION; SHORT COURSE THERAPY; SINGLE DRUG DOSE; SUTHERLANDIA FRUTESCENS;

ADMINISTRATION, ORAL; ANIMALS; CELL LINE, TUMOR; CYTOCHROME P-450 CYP3A; DRUG EVALUATION, PRECLINICAL; FABACEAE; FORMAZANS; HERB-DRUG INTERACTIONS; HUMANS; MALE; NEVIRAPINE; PLANT EXTRACTS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE INHIBITORS; TETRAZOLIUM SALTS; TIME FACTORS;

EID: 79958013998     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.04.051     Document Type: Article

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