Impact of African herbal medicines on antiretroviral metabolism

AIDS

Volumn 19, Issue 1, 2005, Pages 95-97

  Mills, Edward ^a,e   Foster, Brian C ^b   Van Heeswijk, Rolf ^c   Phillips, Elizabeth ^d   Wilson, Kumanan ^d   Leonard, Blair ^d   Kosuge, Kazuhiro ^d   Kanfer, Isadore ^f  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e CANADIAN COLLEGE OF NATUROPATHIC MEDICINE   (Canada)

^f RHODES UNIVERSITY   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; CYTOCHROME P450 3A4; GLYCOPROTEIN P; HYPOXIS HEMEROCALLIDEA EXTRACT; NELFINAVIR; PLANT EXTRACT; PREGNANE X RECEPTOR; RIFAMPICIN; SUTHERLANDIA EXTRACT; UNCLASSIFIED DRUG; VERAPAMIL;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; DRUG TOXICITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPOXIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TREATMENT FAILURE; VIRUS RESISTANCE;

EID: 12144265481     PISSN: 02699370     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002030-200501030-00013     Document Type: Article

References (5)

1. ART roll-out begins today. Sunday Times, South Africa. Available at: http://www.sundaytimes.co.za/zones/sundaytimes/newsst/ newsst1080795554.asp Accessed 13 August 2004.
2. South African Development Committee. Ministerial consultative meeting on nutrition and HIV/AIDS. Johannesburg, South Africa; 20 January 2002.
3. Mills E, Montori V, Perri D, Phillips E, Koren G. Natural health products-HIV drug interactions: a systematic review. Int J STD AIDS 2004; in press.
4. Foster BC, Foster MS, Vandenhoek S, Krantis A, Budzinski JW, Arnason JT, et al. An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic. J Pharm Pharm Sci 2001, 4:176-184.
5. Goodwin B, Hodgson E, Liddle C. The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module. Mol Pharmacol 1999, 56:1329-1339.