Caveolin is present in intestinal cells: Role in cholesterol trafficking?

Journal of Lipid Research

Volumn 39, Issue 10, 1998, Pages 1938-1950

  Field, F Jeffrey ^a   Born, Ella ^a   Murthy, Shubha ^a   Mathur, Satya N ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

CaCo 2 cells; Caveolae; Cholesterol transport; Intestine

Indexed keywords

CAVEOLIN; CHOLESTEROL; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CHOLESTEROL TRANSPORT; ENDOPLASMIC RETICULUM; INTESTINE CELL; INTRACELLULAR TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION;

BIOLOGICAL TRANSPORT; BIOPSY; BLOTTING, NORTHERN; BLOTTING, WESTERN; CACO-2 CELLS; CAVEOLIN 1; CAVEOLINS; CELL MEMBRANE; CHOLESTEROL; DETERGENTS; DUODENUM; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; HUMANS; INTESTINES; MEMBRANE PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SOLUBILITY;

EID: 0031706594     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (65)

1. Stange, E. F., and J. M. Dietschy. 1983. Cholesterol synthesis and low density lipoprotein uptake are regulated independently in rat small intestinal epithelium. Proc. Natl. Acad. Sci. USA. 80: 5739-5743.
2. Field, F. J., E. Born, and S. N. Mathur. 1995. Triacylglycerol-rich lipoprotein cholesterol is derived from the plasma membrane in CaCo-2 cells. J. Lipid Res. 36: 2651-2660.
3. Field, F. J., E. Born, H. Chen, S. Murthy, and S. N. Mathur. 1995. Esterification of plasma membrane cholesterol and triacylglycerol-rich lipoprotein secretion in CaCo-2 cells: possible role of p-glycoprotein. J. Lipid Res. 36: 1533-1543.
4. Christiansen, K., and J. Carlsen. 1981. Microvillus membrane vesicles from pig small intestine. Purity and lipid composition. Biochim. Biophys. Acta. 647: 188-195.
5. Brown, D. A., and J. K. Rose. 1992. Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface. Cell. 68: 533-544.
6. Anderson, R. G., B. A. Kamen, K. G. Rothberg, and S. W. Lacey. 1992. Potocytosis: sequestration and transport of small molecules by caveolae. Science. 255: 410-411.
7. Anderson, R. G. 1993. Caveolae: where incoming and outgoing messengers meet. Proc. Natl. Acad. Sci. USA. 90: 10909-10913.
8. Anderson, R. G. 1993. Plasmalemmal caveolae and GPI-anchored membrane proteins. Curr. Opin. Cell Biol. 5: 647-652.
9. Chang, W. J., Y. S. Ying, K. G. Rothberg, N. M. Hooper, A. J. Turner, H. A. Gambliel, J. De Gunzburg, S. M. Mumby, A. G. Gilman, and R. G. Anderson. 1994. Purification and characterization of smooth muscle cell caveolae. J. Cell Biol. 126: 127-138.
10. Lisanti, M. P., P. E. Scherer, Z. Tang, and M. Sargiacomo. 1994. Caveolae, caveolin, and caveolin-rich membrane domains: a signalling hypothesis. Trends Cell Biol. 4: 231-235.
11. Fielding, P. E., and C. J. Fielding. 1995. Plasma membrane caveolae mediate the efflux of cellular free cholesterol. Biochemistry. 34: 14288-14292.
12. Liu, J., P. Oh, T. Horner, R. A. Rogers, and J. E. Schnitzer. 1997. Organized endothelial cell surface signal transduction in caveolae distinct from glycosylphosphatidylinositol-anchored protein microdomains. J. Biol. Chem. 272: 7211-7222.
13. Lisanti, M. P., Z. L. Tang, and M. Sargiacomo. 1993. Caveolin forms a hetero-oligomeric protein complex that interacts with an apical GPI-linked protein: implications for the biogenesis of caveolae. J. Cell Biol. 123: 595-604.
14. Murata, M., J. Peranen, R. Schreiner, F. Wieland, T. V. Kurzchalia, and K. Simons. 1995. VIP21/caveolin is a cholesterol-binding protein. Proc. Nat. Acad. Sci. USA. 92: 10339-10343.
15. Smart, E. J., Y. S. Ying, P. A. Conrad, and R. G. Anderson. 1994. Caveolin moves from caveolae to the Golgi apparatus in response to cholesterol oxidation. J. Cell Biol. 127: 1185-1197.
16. Conrad, P. A., E. J. Smart, Y. S. Ying, R. G. Anderson, and G. S. Bloom. 1995. Caveolin cycles between plasma membrane caveolae and the Golgi complex by microtubule-dependent and microtubule-independent steps. J. Cell Biol. 131: 1421-1433.
17. Kurzchalia, T. V., P. Dupree, and S. Monier. 1994. VIP21-caveolin, a protein of the trans-Golgi network and caveolae. FEBS Lett. 346: 88-91.
18. Dupree, P., R. G. Parton, G. Raposo, T. V. Kurzchalia, and K. Simons. 1993. Caveolae and sorting in the trans-Golgi network of epithelial cells. EMBO J. 12: 1597-1605.
19. Mayor, S., K. G. Rothberg, and F. R. Maxfield. 1994. Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science. 264: 1948-1951.
20. Mirre, C., L. Monlauzeur, M. Garcia, M. H. Delgrossi, and A. Le Bivic. 1996. Detergent-resistant membrane microdomains from Caco-2 cells do not contain caveolin. Am. J. Physiol. 271: C887-C894.
21. Vogel, U., K. Sandvig, and B. Vandeurs. 1998. Expression of caveolin-1 and polarized formation of invaginated caveolae in Caco-2 and MDCK II cells. J. Cell Sci. 111: 825-832.
22. Field, F. J., E. Albright, and S. N. Mathur. 1987. Regulation of cholesterol esterification by micellar cholesterol in CaCo-2 cells. J. Lipid Res. 28: 1057-1066.
23. Glenney, J. R., Jr. 1992. The sequence of human caveolin reveals identity with VIP21, a component of transport vesicles. FEBS Lett. 314: 45-48.
24. Sanguinetti, C. J., E. Dias Neto, and A. J. Simpson. 1994. Rapid silver staining and recovery of PCR products separated on polyacrylamide gels. BioTechniques. 17: 914-921.
25. Hammerl, P., and J. Thalhamer. 1996. Removal of template after random priming yields DNA probes of maximal specific activity. BioTechniques. 21: 414-416.
26. Doucet, J. P., B. J. Murphy, and B. S. Tuana. 1990. Modification of a discontinuous and highly porous sodium dodecyl sulfate-polyacrylamide gel system for minigel electrophoresis. Anal. Biochem. 190: 209-211.
27. Waheed, A. A., and P. D. Gupta. 1996. Estimation of protein using eosin B dye. Anal. Biochem. 233: 249-252.
28. Munro, H. N. 1966. The determination of nucleic acids. Methods Biochem. Anal. 14: 113-176.
29. Beaufay, H., A. Amar-Costesec, E. Feytmans, D. Thines-Sempoux, M. Wibo, M. Robbi, and J. Berthet. 1974. Analytical study of microsomes and isolated subcellular membranes from rat liver. I. Biochemical methods. J. Cell Biol. 61: 188-200.
30. Scherer, P. E., M. P. Lisanti, G. Baldini, M. Sargiacomo, C. C. Mastick, and H. F. Lodish. 1994. Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles. J. Cell Biol. 127: 1233-1243.
31. Stevens, V. L., and J. H. Tang. 1997. Fumonisin B-1-induced sphingolipid depletion inhibits vitamin uptake via the glycosylphosphatidylinositol-anchored folate receptor. J. Biol. Chem. 272: 18020-18025.
32. Monier, S., R. G. Parton, E. Vogel, J. Behlke, A. Henske, and T. V. Kurzchalia. 1995. VIP21-caveolin, a membrane protein constituent of the caveolar coat, oligomerizes in vivo and in vitro. Mol. Biol. Cell. 6: 911-927.
33. Monier, S., D. J. Dietzen, W. R. Hastings, D. M. Lublin, and T. V. Kurzchalia. 1996. Oligomerization of VIP21-caveolin in vitro is stabilized by long chain fatty acylation or cholesterol. FEBS Lett. 388: 143-149.
34. Sargiacomo, M., P. E. Scherer, Z. Tang, E. Kubler, K. S. Song, M. C. Sanders, and M. P. Lisanti. 1995. Oligomeric structure of caveolin: implications for caveolae membrane organization. Proc. Natl. Acad. Sci. USA. 92: 9407-9411.
35. Hanby, A. M., R. Chinery, R. Poulsom, R. J. Playford, and M. Pignatelli. 1996. Down-regulation of E-cadherin in the reparative epithelium of the human gastrointestinal tract. Am. J. Pathol. 148: 723-729.
36. Zahraoui, A., G. Joberty, M. Arpin, J. J. Fontaine, R. Hellio, A. Tavitian, and D. Louvard. 1994. A small rab GTPase is distributed in cytoplasmic vesicles in nonpolarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells. J. Cell Biol. 124: 101-115.
37. Ahmed, S. N., D. A. Brown, and E. London. 1997. On the origin of sphingolipid/cholesterol-rich detergent-insoluble cell membranes: physiological concentrations of cholesterol and sphingolipid induce formation of a detergent-insoluble, liquid-ordered lipid phase in model membranes. Biochemistry. 36: 10944-10953.
38. Millan, J., R. Puertollano, L. Fan, and M. A. Alonso. 1997. Caveolin and MAL, two protein components of internal detergent-insoluble membranes, are in distinct lipid microenvironments in MDCK cells. Biochem. Biophys. Res. Commun. 233: 707-712.
39. Mayor, S., and F. R. Maxfield. 1995. Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment. Mol. Biol. Cell. 6: 929-944.
40. Fra, A. M., E. Williamson, K. Simons, and R. G. Parton. 1994. Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae. J. Biol. Chem. 269: 30745-30748.
41. Parton, R. G., and K. Simons. 1995. Digging into caveolae [comment]. Science. 269: 1398-1399.
42. Gorodinsky, A., and D. A. Harris. 1995. Glycolipid-anchored proteins in neuroblastoma cells form detergent-resistant complexes without caveolin. J. Cell Biol. 129: 619-627.
43. Rothberg, K. G., Y. S. Ying, B. A. Kamen, and R. G. Anderson. 1990. Cholesterol controls the clustering of the glycophospholipid-anchored membrane receptor for 5-methyltetrahydrofolate. J. Cell Biol. 111: 2931-2938.
44. Schnitzer, J. E., P. Oh, E. Pinney, and J. Allard. 1994. Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules. J. Cell Biol. 127: 1217-1232.
45. Schnitzer, J. E., J. Liu, and P. Oh. 1995. Endothelial caveolae have the molecular transport machinery for vesicle budding, docking, and fusion including VAMP, NSF, SNAP, annexins, and GTPases. J. Biol. Chem. 270: 14399-14404.
46. Chang, W. J., K. G. Rothberg, B. A. Kamen, and R. G. Anderson. 1992. Lowering the cholesterol content of MA104 cells inhibits receptor-mediated transport of folate. J. Cell Biol. 118: 63-69.
47. Parton, R. G., B. Joggerst, and K. Simons. 1994. Regulated internalization of caveolae. J. Cell Biol. 127: 1199-1215.
48. Chen, H., E. Born, S. N. Mathur, F. C. Johlin, Jr., and F. J. Field. 1992. Sphingomyelin content of intestinal cell membranes regulates cholesterol absorption. Evidence for pancreatic and intestinal cell sphingomyelinase activity. Biochem. J. 286: 771-777.
49. Field, F. J., T. Shreves, D. Fujiwara, S. Murthy, E. Albright, and S. N. Mathur. 1991. Regulation of gene expression and synthesis and degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by micellar cholesterol in CaCo-2 cells. J. Lipid Res. 32: 1811-1821.
50. Danielsen, E. M. 1995. Involvement of detergent-insoluble complexes in the intracellular transport of intestinal brush border enzymes. Biochemistry. 34: 1596-1605.
51. Scheiffele, P., Verkade, M. Fra, I. I. Virta, K. Simons, and E. Ikonen. 1998. Caveolin-1 and -2 in the exocytic pathway of MDCK cells. J. Cell Biol. 140: 795-806.
52. Giannoni, F., F. J. Field, and N. O. Davidson. 1994. An improved reverse transcription-polymerase chain reaction method to study apolipoprotein gene expression in Caco-2 cells. J. Lipid Res. 35: 340-350.
53. Vachon, P. H., and J. F. Beaulieu. 1992. Transient mosaic patterns of morphological and functional differentiation in the Caco-2 cell line. Gastroenterology. 103: 414-423.
54. Field, F. J., D. Fujiwara, E. Born, D. A. Chappell, and S. N. Mathur. 1993. Regulation of LDL receptor expression by luminal sterol flux in CaCo-2 cells. Arterioscler. Thromb. 13: 729-737.
55. Lange, Y., and T. L. Steck. 1994. Cholesterol homeostasis. Modulation by amphiphiles. J. Biol. Chem. 269: 29371-29374.
56. Hapala, I., J. Kavecansky, P. Butko, T. J. Scallen, C. H. Joiner, and F. Schroeder. 1994. Regulation of membrane cholesterol domains by sterol carrier protein-2. Biochemistry. 33: 7682-7690.
57. Liscum, L., and K. W. Underwood. 1995. Intracellular cholesterol transport and compartmentation. J. Biol. Chem. 270: 15443-15446.
58. Smart, E. J., Y. Ying, W. C. Donzell, and R. G. Anderson. 1996. A role for caveolin in transport of cholesterol from endoplasmic reticulum to plasma membrane. J. Biol. Chem. 271: 29427-29435.
59. Hailstones, D., L. S. Sleer, R. G. Parton, and K. K. Stanley. 1998. Regulation of caveolin and caveolae by cholesterol in MDCK cells. J. Lipid Res. 39: 369-379.
60. Mathur, S. N., E. Born, W. P. Bishop, and F. J. Field. 1993. Effect of okadaic acid on apoB and apoA-I secretion by CaCo-2 cells. Biochim. Biophys. Acta. 1168: 130-143.
61. Fielding, C. J., A. Bist, and P. E. Fielding. 1997. Caveolin mRNA levels are up-regulated by free cholesterol and down-regulated by oxysterols in fibroblast monolayers. Proc. Natl. Acad. Sci. USA. 94: 3753-3758.
62. Hanada, K., M. Nishijima, Y. Akamatsu, and R. E. Pagano. 1995. Both sphingolipids and cholesterol participate in the detergent insolubility of alkaline phosphatase, a glycosylphosphatidylinositol-anchored protein, in mammalian membranes. J. Biol. Chem. 270: 6254-6260.
63. Murthy, S., E. Albright, S. N. Mathur, N. O. Davidson, and F. J. Field. 1992. Apolipoprotein B mRNA abundance is decreased by eicosapentaenoic acid in CaCo-2 cells. Effect on the synthesis and secretion of apolipoprotein B. Arterioscler. Thromb. 12: 691-700.
64. Mathur, S. N., E. Born, S. Murthy, and F. J. Field. 1997. Microsomal triglyceride transfer protein in CaCo-2 cells: characterization and regulation. J. Lipid Res. 38: 61-67.
65. Orlandi, P. A., and P. H. Fishman. 1998. Filipin-dependent inhibition of cholera toxin: evidence for toxin internalization and activation through caveolae-like domains. J. Cell Biol. 141: 905-915.