Synthesis and anti-tumor activities of some new pyridazinones containing the 2-phenyl-1H-indolyl moiety

Journal of Chemical and Pharmaceutical Research

Volumn 3, Issue 3, 2011, Pages 248-259

  Abd El Ghaffar, Nahed F ^a   Mohamed, Mona Kh ^a   Kadah, Mona S ^a   Radwan, Azza M ^a   Said, Galal H ^b   Abd el Al, Sara N ^a  

^a Al Azhar University   (Egypt)

^b Ain Shams University   (Egypt)

Author keywords

Oxazinone and antitumor activity; Pyridazinone

Indexed keywords

1 [6 (3,4 DIMETHYLPHENYL) 4 (2 PHENYL 1H INDOL 3 YL)PYRIDAZIN 3YL] 2 PHENYLHYDRAZINE; 1 [6 (3,4 DIMETHYLPHENYL) 4 (2 PHENYL 1H INDOL 3 YL)PYRIDAZIN 3YL]HYDRAZINE; 3 [3 CHLORO 6 (3,4 DIMETHYLPHENYL)PYRIDAZIN 4 YL] 2 PHENYL 1H INDOL; 4 (3,4 DIMETHYLPHENYL) 4 OXIME (2 PHENYL 1H INDOL 3 YL)BUTANOIC ACID; 4 [6 (3,4 DIMETHYLPHENYL) 4 (2 PHENYL 1H INDOL 3 YL)PYRIDAZIN 3 YLMINO]PHENOL; 4,5 DIHYDRO 6 (3,4 DIMETHYLPHENYL) 4 (2 PHENYL 1H INDOL 3 YL) 2 (PYRROLIDIN 1 YLMETHYL)PYRIDAZIN 3(2H) ONE; 4,5 DIHYDRO 6 (3,4 DIMETHYLPHENYL) 4 (2 PHENYL 1H INDOL 3 YL)PYRIDAZIN 3(2H) ONE; 4,5 DIHYDRO 6 (3,4 DIMETHYLPHENYL) 5 (2 PHENYL 1H INDOL 3 YL)OXAZIN 6 ONE; 5 (2,4,6 TRIMETHOXYBENZYL) 6 (3,4 DIMETHYLPHENYL) 4 (2 PHENYL 1H INDOL 3 YL)PYRIDAZIN 3(2H) ONE; 5 (4 HYDROXYEBENZYL) 6 (3,4 DIMETHYLPHENYL) 4 (2 PHENYL 1H INDOL 3 YL)PYRIDAZIN 3(2H) ONE; 5 BROMO 6 (3,4 DIMETHYLPHENYL) 4 (2 PHENYL 1H INDOL 3 YL)PYRIDAZIN 3(2H) ONE; 6 (3,4 DIMETHYLPHENYL 1H INDOL 3 YL)PYRIDAZIN 3(2H) ONE; 6 (3,4 DIMETHYLPHENYL) 2 METHYL 4 (2 PHENYL 1H INDOL 3 YL) 4,5 DIHYDRO 3 (2H) PYRIDAZINONE; 6 (3,4 DIMETHYLPHENYL) 4 (2 PHENYL 1H INDOL 3 YL) 2 (PHENYLSULFONYL) 4,5 1H (3H) PYRIDINE; 6 (3,4 DIMETHYLPHENYL) 4 (2 PHENYL 1H INDOL 3 YL)PYRIDAZIN 3 AMINE; 6 (3,4 DIMETHYLPHENYL) 4 (2 PHENYL 1H INDOL 3 YL)PYRIDAZIN 3(2H) THIONE; 6 (3,4 DIMETHYLPHENYL) 8 (2 PHENYL 1H INDOL 3 YL)TETRAZOLO[1,5 B]PYRIDAZINE; 6 (3,4 DIMETHYLPHENYL) N (BENZENESULFONYL 2 AMINOPYRIMIDINE) 4 (2 PHENYL 1H INDOL 3 YL)PYRIDAZIN 3 AMINE; 6 (3,4 DIMETHYLPHENYL) N (BENZENESULFONYL 2 AMINOTHIAZOL) 4 (2 PHENYL 1H INDOL 3 YL)PYRIDAZIN 3 AMINE; ETHYL 2 [5,6 DIHYDRO 3 (3,4 DIMETHYLPHENYL) 6 OXO 5 (2 PHENYL 1H INDOL 3 YL)]PYRIDAZIN 1(4H YL) ACETIC ACID; PYRIDAZINONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN HCT116; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CHEMICAL REACTION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IN VITRO STUDY;

EID: 79957900591     PISSN: None     EISSN: 09757384     Source Type: Journal    
DOI: None     Document Type: Article

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