-
1
-
-
1242314379
-
Amide derivatives of [6-(5-Methyl-3-phenylpyrazole-1-yl)-3(2H)- pyridazinone-2-yl]acetic acids as potential analgesic and anti-inflammatory compounds
-
Banoglu, E., Akoglu, Ç., Ünlü, S., Küpeli, E., Yesilada, E., and Sahin, M. F., Amide derivatives of [6-(5-Methyl-3- phenylpyrazole-1-yl)-3(2H)-pyridazinone-2-yl]acetic acids as potential analgesic and anti-inflammatory compounds. Arch. Pharm., 337, 7-14 (2004).
-
(2004)
Arch. Pharm.
, vol.337
, pp. 7-14
-
-
Banoglu, E.1
Akoglu, Ç.2
Ünlü, S.3
Küpeli, E.4
Yesilada, E.5
Sahin, M.F.6
-
2
-
-
0001023001
-
Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2
-
Brooks, P., Emery, P., Evans, J. F., Fener, H., Hawkey, C. J., Patrono, C., Smolen, J., Breedveld, F., Day, R., Dougados, M., Ehrich, E. W., Gijon-Banos, J., Kvien, T. K., Van Rijswijk, M. H., Warner, T., and Zeidler, H., Interpreting the clinical significance of the differential inhibition of cyclooxygenase-1 and cyclooxygenase-2. Rheumatology, 38, 779-788 (1999).
-
(1999)
Rheumatology
, vol.38
, pp. 779-788
-
-
Brooks, P.1
Emery, P.2
Evans, J.F.3
Fener, H.4
Hawkey, C.J.5
Patrono, C.6
Smolen, J.7
Breedveld, F.8
Day, R.9
Dougados, M.10
Ehrich, E.W.11
Gijon-Banos, J.12
Kvien, T.K.13
Van Rijswijk, M.H.14
Warner, T.15
Zeidler, H.16
-
3
-
-
0037023488
-
3-O-substituted benzyl pyridazinone derivatives as COX inhibitors
-
Chintakunta, V. K., Akella, V., Vedula, M. S., Mamnoor, P. K., Mishra, P., Casturi, S. R., Vangoori, A., and Rajagopalan, R., 3-O-substituted benzyl pyridazinone derivatives as COX inhibitors. Eur. J. Med. Chem., 37, 339-347 (2002).
-
(2002)
Eur. J. Med. Chem.
, vol.37
, pp. 339-347
-
-
Chintakunta, V.K.1
Akella, V.2
Vedula, M.S.3
Mamnoor, P.K.4
Mishra, P.5
Casturi, S.R.6
Vangoori, A.7
Rajagopalan, R.8
-
4
-
-
0021036057
-
Nonsteroidal anti-inflammatory drugs and gastrointestinal adverse effects
-
Clinch, D., Banerjee, A. K., Ostick, G., and Levy, D. W., Nonsteroidal anti-inflammatory drugs and gastrointestinal adverse effects. J. R. Coll. Physicians Lond., 17, 228-230 (1983).
-
(1983)
J. R. Coll. Physicians Lond.
, vol.17
, pp. 228-230
-
-
Clinch, D.1
Banerjee, A.K.2
Ostick, G.3
Levy, D.W.4
-
5
-
-
0033806388
-
Synthesis of new pyridazinones substituted by 4-arylpiperazine-1-yl- carbonyl alkyl moieties and their analgesic properties in mice
-
Coudert, P., Rubat, C., Rohet, F., Leal, F., Fialip, J., and Couquelet, J., Synthesis of new pyridazinones substituted by 4-arylpiperazine-1-yl-carbonyl alkyl moieties and their analgesic properties in mice. Pharm. Pharmacol. Commun., 6, 387-396 (2000).
-
(2000)
Pharm. Pharmacol. Commun.
, vol.6
, pp. 387-396
-
-
Coudert, P.1
Rubat, C.2
Rohet, F.3
Leal, F.4
Fialip, J.5
Couquelet, J.6
-
6
-
-
0030026892
-
4,5-Functionalized 6-Phenyl-3(2H)-pyridazinones: Synthesis and Evaluation of Antinociceptive Activity
-
Dal Piaz, V., Giovannoni, M. P., Ciciani, G., Barlocco, D., Giardina, G., Petrone, G., and Clarke, G. D., 4,5-Functionalized 6-Phenyl-3(2H)- pyridazinones: Synthesis and Evaluation of Antinociceptive Activity. Eur. J. Med. Chem., 31, 65-70 (1996).
-
(1996)
Eur. J. Med. Chem.
, vol.31
, pp. 65-70
-
-
Dal Piaz, V.1
Giovannoni, M.P.2
Ciciani, G.3
Barlocco, D.4
Giardina, G.5
Petrone, G.6
Clarke, G.D.7
-
7
-
-
0034062525
-
Studies on some 3(2H)-pyridazinone derivatives with antinociceptive activity
-
Dogruer, D. S., Sahin, M. F., Ünlü, S., and Shigeru, I., Studies on some 3(2H)-pyridazinone derivatives with antinociceptive activity. Arch. Pharm., 333, 79-86 (2000).
-
(2000)
Arch. Pharm.
, vol.333
, pp. 79-86
-
-
Dogruer, D.S.1
Sahin, M.F.2
Ünlü, S.3
Shigeru, I.4
-
8
-
-
84981833437
-
Heilmittelchemiseke Studies in der heterocyclischen Reihe I
-
Druey, J., Meier, Kd., and Eichenberger, K., Heilmittelchemiseke Studies in der heterocyclischen Reihe I. Helv. Chim. Acta, 37, 121-131 (1954).
-
(1954)
Helv. Chim. Acta
, vol.37
, pp. 121-131
-
-
Druey, J.1
Meier, Kd.2
Eichenberger, K.3
-
9
-
-
0035305539
-
Synthesis and antinociceptive activity of 6-substituted-3-pyridazinone derivatives
-
Gökçe, M., Dogruer, D., and Sahin, M. F., Synthesis and antinociceptive activity of 6-substituted-3-pyridazinone derivatives. Farmaco, 56, 233-237 (2001).
-
(2001)
Farmaco
, vol.56
, pp. 233-237
-
-
Gökçe, M.1
Dogruer, D.2
Sahin, M.F.3
-
10
-
-
3242766754
-
Synthesis and evaluation of the analgesic and anti-inflammatory activity of new 3(2H)-pyridazinone derivatives
-
Gökçe, M., Sahin, M. F., Küpeli, E., and Yesilada, E., Synthesis and evaluation of the analgesic and anti-inflammatory activity of new 3(2H)-pyridazinone derivatives. Arzneim. Forsch./Drug Res., 54, 396-401 (2004).
-
(2004)
Arzneim. Forsch./Drug Res.
, vol.54
, pp. 396-401
-
-
Gökçe, M.1
Sahin, M.F.2
Küpeli, E.3
Yesilada, E.4
-
11
-
-
0034721194
-
Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indometacin, as selective cyclooxygenase-2 inhibitors
-
Kalgutkar, A. S., Marnett, A. B., Crews, B. C., Remel, R. P., and Marnett, L. J., Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indometacin, as selective cyclooxygenase-2 inhibitors. J. Med. Chem., 43, 2860-2870 (2000).
-
(2000)
J. Med. Chem.
, vol.43
, pp. 2860-2870
-
-
Kalgutkar, A.S.1
Marnett, A.B.2
Crews, B.C.3
Remel, R.P.4
Marnett, L.J.5
-
12
-
-
0037169972
-
Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors
-
Kalgutkar, A. S., Rowlinson, S. W., Crews, B. C., and Marnett, L. J., Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors. Bioorg. Med. Chem. Lett., 12, 521-524 (2002).
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 521-524
-
-
Kalgutkar, A.S.1
Rowlinson, S.W.2
Crews, B.C.3
Marnett, L.J.4
-
13
-
-
0021805951
-
Antiinflammations Actions of Ephedrines in Acute Inflammations
-
Kasahara, Y., Hikino, H., Tsurufuji, S., Watanabe, M., and Ohuchi, K., Antiinflammations Actions of Ephedrines in Acute Inflammations. Planta Med., 51, 325-331 (1985).
-
(1985)
Planta Med.
, vol.51
, pp. 325-331
-
-
Kasahara, Y.1
Hikino, H.2
Tsurufuji, S.3
Watanabe, M.4
Ohuchi, K.5
-
14
-
-
0027480087
-
Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by acetyl salicylic acid and other nonsteroidal anti-inflammatory drugs
-
Meade, E. A., Smith, W. L., and DeWitt, D. L., Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by acetyl salicylic acid and other nonsteroidal anti-inflammatory drugs. J. Biol. Chem., 268, 6610-6614 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 6610-6614
-
-
Meade, E.A.1
Smith, W.L.2
DeWitt, D.L.3
-
15
-
-
0029816403
-
Synthesis and peripherally acting analgesic 3-arylpiperazinyl-5-benzyl- pyridazines
-
Moreau, S., Coudert, P., Rubat, C., Albuisson, E., and Couquelet, J., Synthesis and peripherally acting analgesic 3-arylpiperazinyl-5-benzyl- pyridazines. Arzneim. Forsch./Drug Res., 46, 800-805 (1996).
-
(1996)
Arzneim. Forsch./Drug Res.
, vol.46
, pp. 800-805
-
-
Moreau, S.1
Coudert, P.2
Rubat, C.3
Albuisson, E.4
Couquelet, J.5
-
16
-
-
17144438069
-
Investigations of new pyridazinone derivatives for the synthesis of potent analgesic and anti-inflammatory compounds with cyclooxygenase inhibitory activity
-
Okçelik, B., Ünlü, S., Banoglu, E., Küpeli, E., Yesilada, E., and Sahin, M. F., Investigations of new pyridazinone derivatives for the synthesis of potent analgesic and anti-inflammatory compounds with cyclooxygenase inhibitory activity. Arch. Pharm., 336, 406-412 (2003).
-
(2003)
Arch. Pharm.
, vol.336
, pp. 406-412
-
-
Okçelik, B.1
Ünlü, S.2
Banoglu, E.3
Küpeli, E.4
Yesilada, E.5
Sahin, M.F.6
-
17
-
-
0000782975
-
The effects of aggregation, electric shock, and adrenergic blocking drugs on inhibition of the "writhing syndrome"
-
Okun, R., Liddon, S. C., and Lasagnal, L., The effects of aggregation, electric shock, and adrenergic blocking drugs on inhibition of the "writhing syndrome". J. Pharmacol. Exp. Ther., 139, 107-114 (1963).
-
(1963)
J. Pharmacol. Exp. Ther.
, vol.139
, pp. 107-114
-
-
Okun, R.1
Liddon, S.C.2
Lasagnal, L.3
-
18
-
-
0023178776
-
The clinical significance of inhibition of renal prostaglandin synthesis
-
Patrono, C. and Dunn, M. J., The clinical significance of inhibition of renal prostaglandin synthesis. Kidney Int., 32, 1-12 (1987).
-
(1987)
Kidney Int.
, vol.32
, pp. 1-12
-
-
Patrono, C.1
Dunn, M.J.2
-
19
-
-
0033588518
-
Antinociceptive activity of a 3(2H)-pyridazinone derivative in mice
-
Pieretti, S., Dal Piaz, V., Matucci, R., Giovannoni, M. P., and Galli, A., Antinociceptive activity of a 3(2H)-pyridazinone derivative in mice. Life Sci., 65, 1381-1394 (1999).
-
(1999)
Life Sci.
, vol.65
, pp. 1381-1394
-
-
Pieretti, S.1
Dal Piaz, V.2
Matucci, R.3
Giovannoni, M.P.4
Galli, A.5
-
20
-
-
0029978670
-
Synthesis and trazodone-like analgesic activity of 4-phenyl-6-aryl-2-[3- (4-arylpiperazin-1-yl)propyl]pyridazin-3-ones
-
Rohet, F., Rubat, C., Coudert, P., Albuisson, E., and Couquelet, J., Synthesis and trazodone-like analgesic activity of 4-phenyl-6-aryl-2-[3-(4- arylpiperazin-1-yl)propyl]pyridazin-3-ones. Chem. Pharm. Bull., 44, 980-986 (1996).
-
(1996)
Chem. Pharm. Bull.
, vol.44
, pp. 980-986
-
-
Rohet, F.1
Rubat, C.2
Coudert, P.3
Albuisson, E.4
Couquelet, J.5
-
21
-
-
0023949447
-
Synthesis and analgesic effect of N-substituted 5-arylidene-6-methyl- 3(4H)-pyridazinones
-
Rubat, C., Coudert, P., Couquelet, J., Bastide, P., and Bastide, J., Synthesis and analgesic effect of N-substituted 5-arylidene-6-methyl-3(4H)- pyridazinones. Chem. Pharm. Bull., 36,1558-1561 (1988).
-
(1988)
Chem. Pharm. Bull.
, vol.36
, pp. 1558-1561
-
-
Rubat, C.1
Coudert, P.2
Couquelet, J.3
Bastide, P.4
Bastide, J.5
-
22
-
-
0024444033
-
Synthesis and Pharmacological Evaluation of N-Substituted 4,6-Diaryl-3-pyridazinones as Analgesic, Antiinflammatory and Antipyretic Agents
-
Rubat, C., Coudert, P., Tronche, P., Bastide, J., Bastide, P., and Privat, A. M., Synthesis and Pharmacological Evaluation of N-Substituted 4,6-Diaryl-3-pyridazinones as Analgesic, Antiinflammatory and Antipyretic Agents. Chem. Pharm. Bull., 37, 2832-2835 (1989).
-
(1989)
Chem. Pharm. Bull.
, vol.37
, pp. 2832-2835
-
-
Rubat, C.1
Coudert, P.2
Tronche, P.3
Bastide, J.4
Bastide, P.5
Privat, A.M.6
-
23
-
-
0027054583
-
Synthesis of Mannich bases of arylidene-pyridazinones as analgesic agents
-
Rubat, C., Coudert, P., Albuisson, E., Bastide, J., Couquelet, J., and Tronche, P., Synthesis of Mannich bases of arylidene-pyridazinones as analgesic agents. J. Pharm. Sci., 81, 1084-1087 (1992).
-
(1992)
J. Pharm. Sci.
, vol.81
, pp. 1084-1087
-
-
Rubat, C.1
Coudert, P.2
Albuisson, E.3
Bastide, J.4
Couquelet, J.5
Tronche, P.6
-
24
-
-
0022398581
-
Synthesis and Pharmacological Study of A Series of 3(2H)-pyridazinones as Analgesic and Anti-inflammatory Agents
-
Santagati, N. A., Duro, F., Caruso, A., Trombadore, S., and Amico-Roxas, M., Synthesis and Pharmacological Study of A Series of 3(2H)-pyridazinones as Analgesic and Anti-inflammatory Agents. Farmaco, 40, 921-929 (1985).
-
(1985)
Farmaco
, vol.40
, pp. 921-929
-
-
Santagati, N.A.1
Duro, F.2
Caruso, A.3
Trombadore, S.4
Amico-Roxas, M.5
-
25
-
-
0018721897
-
Studies in the field of pyridazine compounds, III (1). Hypotensive 3-(1-Pyrazolyl)-pyridazine derivatives
-
Szilagyi, G., Kasztreiner, E., Tardos, L., Jaszlits, L., Kosa, E., Cseh, G., Tolnay, P., and Kovacs-Szabo, I., Studies in the field of pyridazine compounds, III (1). Hypotensive 3-(1-Pyrazolyl)-pyridazine derivatives. Eur. J. Med. Chem., 14, 439-445 (1979).
-
(1979)
Eur. J. Med. Chem.
, vol.14
, pp. 439-445
-
-
Szilagyi, G.1
Kasztreiner, E.2
Tardos, L.3
Jaszlits, L.4
Kosa, E.5
Cseh, G.6
Tolnay, P.7
Kovacs-Szabo, I.8
-
26
-
-
0018770790
-
A new nonsteroidal analgesic-antiinflammatory agent. Synthesis and activity of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone and related compounds
-
Takaya, M., Sato, M., Terashima, K., and Tanizawa, H., A new nonsteroidal analgesic-antiinflammatory agent. Synthesis and activity of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone and related compounds. J. Med. Chem., 22, 53-58 (1979).
-
(1979)
J. Med. Chem.
, vol.22
, pp. 53-58
-
-
Takaya, M.1
Sato, M.2
Terashima, K.3
Tanizawa, H.4
-
27
-
-
0014478438
-
Biphasic development of carrageenin edema in rats
-
Vinegar, R., Schreiber, W., and Hugo, R., Biphasic development of carrageenin edema in rats. J. Pharmacol. Exp. Ther., 166, 96-103 (1969).
-
(1969)
J. Pharmacol. Exp. Ther.
, vol.166
, pp. 96-103
-
-
Vinegar, R.1
Schreiber, W.2
Hugo, R.3
-
28
-
-
0023174631
-
Pathway to carrageenan-induced inflammation in the hind limb of the rat
-
Vinegar, R., Truax, J. F., Selph, J. L., Johnston, P. R., Venable, A. L., and McKenzie, K. K., Pathway to carrageenan-induced inflammation in the hind limb of the rat. Fed. Proc., 46, 118-126 (1987).
-
(1987)
Fed. Proc.
, vol.46
, pp. 118-126
-
-
Vinegar, R.1
Truax, J.F.2
Selph, J.L.3
Johnston, P.R.4
Venable, A.L.5
McKenzie, K.K.6
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