α1-adrenoceptor antagonists. 5. Pyridazinone-arylpiperazines. Probing the influence on affinity and selectivity of both ortho-alkoxy groups at the arylpiperazine moiety and cyclic substituents at the pyridazinone nucleus

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 2, 2003, Pages 171-173

  Betti, Laura ^a   Floridi, Monia ^b   Giannaccini, Gino ^a   Manetti, Fabrizio ^c   Strappaghetti, Giovannella ^b   Tafi, Andrea ^c   Botta, Maurizio ^c  

^a UNIVERSITY OF PISA   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

^c UNIVERSITY OF SIENA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTOR BLOCKING AGENT; ALKOXYPHENYLPIPERAZINYLHEPTYLPYRIDAZINONE; ALPHA 1 ADRENERGIC RECEPTOR; FUNCTIONAL GROUP; PIPERAZINE; PRAZOSIN; PYRIDAZINONE DERIVATIVE; UNCLASSIFIED DRUG; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; PYRIDAZINE DERIVATIVE; SEROTONIN 1 RECEPTOR; SEROTONIN RECEPTOR;

ARTICLE; BINDING AFFINITY; DRUG ANTAGONISM; DRUG SELECTIVITY; DRUG SYNTHESIS; CYCLIZATION; DRUG EFFECT; PHYSICAL CHEMISTRY; RADIOASSAY; SYNTHESIS;

ADRENERGIC ALPHA-ANTAGONISTS; CHEMISTRY, PHYSICAL; CYCLIZATION; PYRIDAZINES; RADIOLIGAND ASSAY; RECEPTORS, ADRENERGIC, ALPHA-1; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1;

EID: 1842855046     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(02)00932-0     Document Type: Article

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