Amlodipine and atorvastatin exert protective and additive effects via antiapoptotic and antiautophagic mechanisms after transient middle cerebral artery occlusion in Zucker metabolic syndrome rats

Journal of Neuroscience Research

Volumn 89, Issue 8, 2011, Pages 1228-1234

  Zhang, Xuemei ^a   Deguchi, Shoko ^a   Deguchi, Kentaro ^a   Ohta, Yasuyuki ^a   Yamashita, Toru ^a   Shang, Jingwei ^a   Tian, Fengfeng ^a   Liu, Ning ^a   Liu, Wentao ^a   Ikeda, Yoshio ^a   Matsuura, Tohru ^a   Abe, Koji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Amlodipine; Apoptosis; Atorvastatin; Autophagy; Cerebral ischemia

Indexed keywords

AMLODIPINE; ATORVASTATIN; MICROTUBULE ASSOCIATED PROTEIN 1; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; BRAIN INFARCTION SIZE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; EVENING DOSAGE; IMMUNOHISTOCHEMISTRY; MIDDLE CEREBRAL ARTERY OCCLUSION; MONOTHERAPY; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STROKE; ZUCKER RAT;

AMLODIPINE; ANIMALS; ANTIHYPERTENSIVE AGENTS; APOPTOSIS; AUTOPHAGY; BRAIN; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; PYRROLES; RATS; RATS, ZUCKER;

EID: 79957819232     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22633     Document Type: Article

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