Impaired nitric oxide modulation of myocardial oxygen consumption in genetically cardiomyopathic hamsters

Journal of Molecular and Cellular Cardiology

Volumn 32, Issue 12, 2000, Pages 2299-2306

  Loke, Kit E ^a   Messina, Eric J ^a   Mital, Seema ^b   Hintze, Thomas H ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b Columbia University College of Physicians and Surgeons ^*  (United States)

Author keywords

Amlodipine; Angiotensin converting enzyme inhibitor; Kinin; Syrian hamsters

Indexed keywords

AMLODIPINE; BRADYKININ; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; KININ; N ACETYL S NITROSOPENICILLAMINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; RAMIPRILAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; CONTROLLED STUDY; ECHOCARDIOGRAPHY; HEART DILATATION; HEART EJECTION FRACTION; HEART FAILURE; HEART LEFT VENTRICLE WALL; HEART MUSCLE OXYGEN CONSUMPTION; MITOCHONDRIAL RESPIRATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; SYRIAN HAMSTER;

EID: 0034513220     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.2000.1258     Document Type: Article

References (36)

1. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial
2. Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure
3. Effects of quinapril, a new angiotensin converting enzyme inhibitor, on left ventricular failure and survival in the cardiomyopathic hamster
4. Effects of early and late therapy with perindopril on survival and myocardial inotropic state in experimental dilated cardiomyopathy
5. ACE inhibitors promote nitric oxide accumulation to modulate myocardial oxygen consumption
6. 2-kinin receptor knockout mice
7. Endogenous endothelial nitric oxide synthase-derived nitric oxide is a physiological regulator of myocardial oxygen consumption
8. ACE inhibitors induce the release of endogenous eNOS-derived nitric oxide to decrease myocardial oxygen consumption
9. On the mechanism by which vascular endothelial cells regulate their oxygen consumption
10. Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide. Implications for neurodegenerative diseases
11. Nanomolar concentrations of nitric oxide reversibly inhibit synaptosomal respiration by competing with oxygen at cytochrome oxidase
12. Oxidative phosphorylation and calcium transport of mitochondria isolated from cardiomyopathic hamster hearts
13. Oxidative phosphorylation in cardiomyopathic hamsters
14. Energy levels at systole vs. diastole in normal hamster hearts vs. myopathic hamster hearts
15. Reduced gene expression of vascular endothelial NO synthase and cyclooxygenase-1 in heart failure
16. Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog
17. Amlodipine releases nitric oxide from canine coronary microvessels: An unexpected mechanism of action of a calcium channel-blocking agent
18. The solubility of oxygen
19. Kinin-mediated coronary nitric oxide production contributes to the therapeutic action angiotensin-converting enzyme and neutral endopeptidase inhibitors and amlodipine in the treatment of heart failure
20. Endothelium-dependent dilation of the coronary microvasculature is impaired in dilated cardiomyopathy
21. 2 consumption in the nonhuman primate: An additional mechanism of action of amlodipine
22. Role of endothelial kinins in control of coronary nitric oxide production
23. Amlodipine promotes kinin-mediated nitric oxide production in coronary microvessels of failing human hearts
24. Local cardiac kininogen production modulates tissue oxygen consumption in hearts from Brown Norway rats
25. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
26. Effect of amlodipine on morbidity and mortality in severe chronic heart failure
27. Chronic effects of enalapril and amlodipine on cardiac remodeling in cardiomyopathic hamster hearts
28. Progressive cardiac dysfunction and fibrosis in the cardiomyopathic hamster and effects of growth hormone and angiotensin-converting enzyme inhibition
29. Vascular alterations during the development and progression of experimental heart failure
30. Superoxide anions contribute to impaired regulation of blood pressure by nitric oxide during the development of cardiomyopathy
31. Mitochondrial electron transport complex I is a potential source of oxygen free radicals in failing myocardium
32. Role of endothelium-derived nitric oxide in the modulation of canine myocardial mitochondriai respiration in vitro: Implications for the development of heart failure
33. Defective oxidative phosphorylation in hereditary myocardiopathy in the Syrian hamster
34. Nitric oxide modulates mitochondrial respiration in rafting human heart
35. Spontaneous hereditary myocardial degeneration and congestive heart failure in a strain of Syrian hamsters
36. Hereditary and acquired cardiomyopathies in experimental animals: Mechanical, biochemical, and structural features