Increased sensitivity to antigen in high avidity CD8+ T cells results from augmented membrane proximal T-cell receptor signal transduction

Immunology

Volumn 133, Issue 3, 2011, Pages 307-317

  Sharma, Sharad K ^a,b   Alexander Miller, Martha A ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b ROCHESTER GENERAL HOSPITAL   (United States)

Author keywords

CD8; CD8+ effector cell; Differentiation; Functional avidity; Signalling

Indexed keywords

ANTIGEN; CALCIUM; CD2 ANTIGEN; CD3 ANTIGEN; CD45 ANTIGEN; CD8 ANTIGEN; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1; MAJOR HISTOCOMPATIBILITY ANTIGEN; MEMBRANE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PEPTIDE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; IMMUNOMODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, BACTERIAL; ANTIGENS, VIRAL; CYTOTOXICITY, IMMUNOLOGIC; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FLOW CYTOMETRY; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PEPTIDES; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC;

EID: 79957801930     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2011.03440.x     Document Type: Article

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