메뉴 건너뛰기




Volumn 108, Issue 21, 2011, Pages 8737-8742

A cluster of coregulated genes determines TGF-β - Induced regulatory T-cell (Treg) dysfunction in NOD mice

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; CARRIER PROTEIN; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; PROTEIN LRRC32; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

EID: 79957764739     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1105364108     Document Type: Article
Times cited : (33)

References (50)
  • 1
    • 0033682056 scopus 로고    scopus 로고
    • B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes
    • Salomon B, et al. (2000) B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes. Immunity 12:431-440.
    • (2000) Immunity , vol.12 , pp. 431-440
    • Salomon, B.1
  • 2
    • 2942692039 scopus 로고    scopus 로고
    • + T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
    • DOI 10.1084/jem.20040180
    • Tarbell KV, Yamazaki S, Olson K, Toy P, Steinman RM (2004) CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J Exp Med 199:1467-1477. (Pubitemid 38780402)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.11 , pp. 1467-1477
    • Tarbell, K.V.1    Yamazaki, S.2    Olson, K.3    Toy, P.4    Steinman, R.M.5
  • 3
    • 2942642383 scopus 로고    scopus 로고
    • In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
    • Tang Q, et al. (2004) In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J Exp Med 199:1455-1465.
    • (2004) J Exp Med , vol.199 , pp. 1455-1465
    • Tang, Q.1
  • 4
    • 2942692037 scopus 로고    scopus 로고
    • + T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion
    • DOI 10.1084/jem.20040179
    • Herman AE, Freeman GJ, Mathis D, Benoist C (2004) CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion. J Exp Med 199:1479-1489. (Pubitemid 38780403)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.11 , pp. 1479-1489
    • Herman, A.E.1    Freeman, G.J.2    Mathis, D.3    Benoist, C.4
  • 6
    • 34047210905 scopus 로고    scopus 로고
    • + regulatory T cells
    • DOI 10.1111/j.1365-2567.2007.02546.x
    • Mellanby RJ, Thomas D, Phillips JM, Cooke A (2007) Diabetes in non-obese diabetic mice is not associated with quantitative changes in CD4+ CD25+ Foxp3+ regulatory T cells. Immunology 121:15-28. (Pubitemid 46537670)
    • (2007) Immunology , vol.121 , Issue.1 , pp. 15-28
    • Mellanby, R.J.1    Thomas, D.2    Phillips, J.M.3    Cooke, A.4
  • 8
    • 43049174722 scopus 로고    scopus 로고
    • Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
    • Tang Q, et al. (2008) Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity 28:687-697.
    • (2008) Immunity , vol.28 , pp. 687-697
    • Tang, Q.1
  • 10
    • 0141992907 scopus 로고    scopus 로고
    • Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development
    • Gregori S, Giarratana N, Smiroldo S, Adorini L (2003) Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development. J Immunol 171:4040-4047. (Pubitemid 37238678)
    • (2003) Journal of Immunology , vol.171 , Issue.8 , pp. 4040-4047
    • Gregori, S.1    Giarratana, N.2    Smiroldo, S.3    Adorini, L.4
  • 11
    • 34447103406 scopus 로고    scopus 로고
    • + cells in BDC2.5NOD mice
    • DOI 10.1111/j.1365-2567.2007.02604.x
    • Thomas DC, Mellanby RJ, Phillips JM, Cooke A (2007) An early age-related increase in the frequency of CD4+ Foxp3+ cells in BDC2.5NOD mice. Immunology 121:565-576. (Pubitemid 47030094)
    • (2007) Immunology , vol.121 , Issue.4 , pp. 565-576
    • Thomas, D.C.1    Mellanby, R.J.2    Phillips, J.M.3    Cooke, A.4
  • 12
    • 58149386381 scopus 로고    scopus 로고
    • The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors
    • D'Alise AM, et al. (2008) The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors. Proc Natl Acad Sci USA 105:19857-19862.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19857-19862
    • D'Alise, A.M.1
  • 13
    • 58149188480 scopus 로고    scopus 로고
    • The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells
    • Schneider A, et al. (2008) The effector T cells of diabetic subjects are resistant to regulation via CD4+ FOXP3+ regulatory T cells. J Immunol 181:7350-7355.
    • (2008) J Immunol , vol.181 , pp. 7350-7355
    • Schneider, A.1
  • 14
    • 2542420993 scopus 로고    scopus 로고
    • In vivo instruction of suppressor commitment in naive T cells
    • Apostolou I, von Boehmer H (2004) In vivo instruction of suppressor commitment in naive T cells. J Exp Med 199:1401-1408.
    • (2004) J Exp Med , vol.199 , pp. 1401-1408
    • Apostolou, I.1    Von Boehmer, H.2
  • 16
    • 46749126890 scopus 로고    scopus 로고
    • Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation
    • Curotto de Lafaille MA, et al. (2008) Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation. Immunity 29:114-126.
    • (2008) Immunity , vol.29 , pp. 114-126
    • Curotto De Lafaille, M.A.1
  • 17
    • 77950527805 scopus 로고    scopus 로고
    • Genomic definition of multiple ex vivo regulatory T cell subphenotypes
    • Feuerer M, et al. (2010) Genomic definition of multiple ex vivo regulatory T cell subphenotypes. Proc Natl Acad Sci USA 107:5919-5924.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 5919-5924
    • Feuerer, M.1
  • 18
    • 34447575642 scopus 로고    scopus 로고
    • + regulatory T cells in Heligmosomoides polygyrus infection
    • DOI 10.1002/eji.200636751
    • Finney CA, Taylor MD, Wilson MS, Maizels RM (2007) Expansion and activation of CD4(+)CD25(+) regulatory T cells in Heligmosomoides polygyrus infection. Eur J Immunol 37:1874-1886. (Pubitemid 47065126)
    • (2007) European Journal of Immunology , vol.37 , Issue.7 , pp. 1874-1886
    • Finney, C.A.M.1    Taylor, M.D.2    Wilson, M.S.3    Maizels, R.M.4
  • 21
    • 34547757390 scopus 로고    scopus 로고
    • Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid
    • Sun CM, et al. (2007) Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid. J Exp Med 204:1775-1785.
    • (2007) J Exp Med , vol.204 , pp. 1775-1785
    • Sun, C.M.1
  • 22
    • 77956254994 scopus 로고    scopus 로고
    • Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints
    • Nishio J, Feuerer M, Wong J, Mathis D, Benoist C (2010) Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints. J Exp Med 207:1879-1889.
    • (2010) J Exp Med , vol.207 , pp. 1879-1889
    • Nishio, J.1    Feuerer, M.2    Wong, J.3    Mathis, D.4    Benoist, C.5
  • 23
    • 85027947787 scopus 로고    scopus 로고
    • Induction of colonic regulatory T cells by indigenous Clostridium species
    • Atarashi K, et al. (2011) Induction of colonic regulatory T cells by indigenous Clostridium species. Science 331:337-341.
    • (2011) Science , vol.331 , pp. 337-341
    • Atarashi, K.1
  • 24
    • 0348223787 scopus 로고    scopus 로고
    • Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
    • ChenW, et al. (2003) Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 198:1875-1886.
    • (2003) J Exp Med , vol.198 , pp. 1875-1886
    • Chen, W.1
  • 25
    • 33846980131 scopus 로고    scopus 로고
    • Epigenetic control of the foxp3 locus in regulatory T cells
    • Floess S, et al. (2007) Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol 5:e38.
    • (2007) PLoS Biol , vol.5
    • Floess, S.1
  • 26
    • 36048978911 scopus 로고    scopus 로고
    • Foxp3 Transcription-Factor-Dependent and -Independent Regulation of the Regulatory T Cell Transcriptional Signature
    • DOI 10.1016/j.immuni.2007.09.010, PII S107476130700492X
    • Hill JA, et al. (2007) Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. Immunity 27:786-800. (Pubitemid 350110546)
    • (2007) Immunity , vol.27 , Issue.5 , pp. 786-800
    • Hill, J.A.1    Feuerer, M.2    Tash, K.3    Haxhinasto, S.4    Perez, J.5    Melamed, R.6    Mathis, D.7    Benoist, C.8
  • 27
    • 42149145285 scopus 로고    scopus 로고
    • Ex vivo generated regulatory T cells modulate experimental autoimmune myasthenia gravis
    • Aricha R, Feferman T, Fuchs S, Souroujon MC (2008) Ex vivo generated regulatory T cells modulate experimental autoimmune myasthenia gravis. J Immunol 180:2132-2139.
    • (2008) J Immunol , vol.180 , pp. 2132-2139
    • Aricha, R.1    Feferman, T.2    Fuchs, S.3    Souroujon, M.C.4
  • 29
    • 50549102020 scopus 로고    scopus 로고
    • TGF-beta-induced Foxp3+ regulatory T cells rescue scurfy mice
    • Huter EN, et al. (2008) TGF-beta-induced Foxp3+ regulatory T cells rescue scurfy mice. Eur J Immunol 38:1814-1821.
    • (2008) Eur J Immunol , vol.38 , pp. 1814-1821
    • Huter, E.N.1
  • 30
    • 69449086689 scopus 로고    scopus 로고
    • Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells
    • Wang R, et al. (2009) Expression of GARP selectively identifies activated human FOXP3+ regulatory T cells. Proc Natl Acad Sci USA 106:13439-13444.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13439-13444
    • Wang, R.1
  • 32
    • 53749094183 scopus 로고    scopus 로고
    • CTLA-4 control over Foxp3+ regulatory T cell function
    • Wing K, et al. (2008) CTLA-4 control over Foxp3+ regulatory T cell function. Science 322:271-275.
    • (2008) Science , vol.322 , pp. 271-275
    • Wing, K.1
  • 33
    • 52649097448 scopus 로고    scopus 로고
    • The Immunological Genome Project: Networks of gene expression in immune cells
    • Immunological Genome Project Consortium
    • Heng TS, Painter MW; Immunological Genome Project Consortium (2008) The Immunological Genome Project: networks of gene expression in immune cells. Nat Immunol 9:1091-1094.
    • (2008) Nat Immunol , vol.9 , pp. 1091-1094
    • Heng, T.S.1    Painter, M.W.2
  • 34
    • 69449085219 scopus 로고    scopus 로고
    • GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells
    • Tran DQ, et al. (2009) GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells. Proc Natl Acad Sci USA 106:13445-13450.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13445-13450
    • Tran, D.Q.1
  • 35
    • 73249123203 scopus 로고    scopus 로고
    • Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg
    • Stockis J, Colau D, Coulie PG, Lucas S (2009) Membrane protein GARP is a receptor for latent TGF-beta on the surface of activated human Treg. Eur J Immunol 39:3315-3322.
    • (2009) Eur J Immunol , vol.39 , pp. 3315-3322
    • Stockis, J.1    Colau, D.2    Coulie, P.G.3    Lucas, S.4
  • 36
    • 77951638740 scopus 로고    scopus 로고
    • Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells
    • Thornton AM, et al. (2010) Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J Immunol 184:3433-3441.
    • (2010) J Immunol , vol.184 , pp. 3433-3441
    • Thornton, A.M.1
  • 39
    • 40049109288 scopus 로고    scopus 로고
    • Interactions between Idd5.1/Ctla4 and other type 1 diabetes genes
    • Hunter K, et al. (2007) Interactions between Idd5.1/Ctla4 and other type 1 diabetes genes. J Immunol 179:8341-8349.
    • (2007) J Immunol , vol.179 , pp. 8341-8349
    • Hunter, K.1
  • 40
    • 0035650699 scopus 로고    scopus 로고
    • Further mapping of the Idd5.1 locus for autoimmune diabetes in NOD mice
    • Lamhamedi-Cherradi SE, et al. (2001) Further mapping of the Idd5.1 locus for autoimmune diabetes in NOD mice. Diabetes 50:2874-2878.
    • (2001) Diabetes , vol.50 , pp. 2874-2878
    • Lamhamedi-Cherradi, S.E.1
  • 43
    • 33644753940 scopus 로고    scopus 로고
    • Defective induction of CTLA-4 in the NOD mouse is controlled by the NOD allele of Idd3/IL-2 and a novel locus (Ctex) telomeric on chromosome 1
    • DOI 10.2337/diabetes.55.02.06.db05-1240
    • Lundholm M, et al. (2006) Defective induction of CTLA-4 in the NOD mouse is controlled by the NOD allele of Idd3/IL-2 and a novel locus (Ctex) telomeric on chromosome 1. Diabetes 55:538-544. (Pubitemid 43343287)
    • (2006) Diabetes , vol.55 , Issue.2 , pp. 538-544
    • Lundholm, M.1    Motta, V.2    Lofgren-Burstrom, A.3    Duarte, N.4    Bergman, M.-L.5    Mayans, S.6    Holmberg, D.7
  • 44
    • 76749133610 scopus 로고    scopus 로고
    • Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
    • Zheng Y, et al. (2010) Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 463:808-812.
    • (2010) Nature , vol.463 , pp. 808-812
    • Zheng, Y.1
  • 45
    • 58149091806 scopus 로고    scopus 로고
    • The "perfect storm" for type 1 diabetes: The complex interplay between intestinal microbiota, gut permeability, and mucosal immunity
    • Vaarala O, Atkinson MA, Neu J (2008) The "perfect storm" for type 1 diabetes: the complex interplay between intestinal microbiota, gut permeability, and mucosal immunity. Diabetes 57:2555-2562.
    • (2008) Diabetes , vol.57 , pp. 2555-2562
    • Vaarala, O.1    Atkinson, M.A.2    Neu, J.3
  • 48
    • 2442567829 scopus 로고    scopus 로고
    • Back to central tolerance
    • DOI 10.1016/S1074-7613(04)00111-6, PII S1074761304001116
    • Mathis D, Benoist C (2004) Back to central tolerance. Immunity 20:509-516. (Pubitemid 38638121)
    • (2004) Immunity , vol.20 , Issue.5 , pp. 509-516
    • Mathis, D.1    Benoist, C.2
  • 49
    • 84856967787 scopus 로고    scopus 로고
    • Defective FoxP3+ Treg cell differentiation in the gut of type 1 diabetic patients
    • Available at Accessed February 21, 2011
    • Badami E, (2010) Defective FoxP3+ Treg cell differentiation in the gut of type 1 diabetic patients. Nat Precedings. Available at http://hdl.handle.net/ 10101/npre.2010.4417.1. Accessed February 21, 2011.
    • (2010) Nat Precedings
    • Badami, E.1
  • 50
    • 77954572010 scopus 로고    scopus 로고
    • Quantitative phosphoproteomic analysis of T cell receptor signaling in diabetes prone and resistant mice
    • Iwai LK, Benoist C, Mathis D, White FM (2010) Quantitative phosphoproteomic analysis of T cell receptor signaling in diabetes prone and resistant mice. J Proteome Res 9:3135-3145.
    • (2010) J Proteome Res , vol.9 , pp. 3135-3145
    • Iwai, L.K.1    Benoist, C.2    Mathis, D.3    White, F.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.