메뉴 건너뛰기




Volumn 415, Issue 1, 2011, Pages 27-31

Single-label time-resolved luminescence assay for estrogen receptor-ligand binding

Author keywords

Drug discovery; Homogeneous assay; Nuclear receptors; Steroids; Time resolved luminescence

Indexed keywords

DRUG PRODUCTS; ENERGY TRANSFER; EUROPIUM COMPOUNDS; FORSTER RESONANCE ENERGY TRANSFER; LIGANDS; QUENCHING;

EID: 79957713225     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2011.03.038     Document Type: Article
Times cited : (7)

References (26)
  • 1
    • 1542314421 scopus 로고    scopus 로고
    • Molecular Mechanisms, Physiological Consequences and Pharmacological Implications of Estrogen Receptor Action
    • DOI 10.2165/00129785-200404010-00003
    • T. Barkhem, S. Nilsson, J. Gustafsson, Molecular mechanisms physiological consequences and pharmacological implications of estrogen receptor action, Am. J. Pharmacogenomics 4 (2004) 19-28. (Pubitemid 38325702)
    • (2004) American Journal of PharmacoGenomics , vol.4 , Issue.1 , pp. 19-28
    • Barkhem, T.1    Nilsson, S.2    Gustafsson, J.-A.3
  • 2
    • 0032478958 scopus 로고    scopus 로고
    • Relationship between estrogen levels use of hormone replacement therapy and breast cancer
    • G. Colditz, Relationship between estrogen levels use of hormone replacement therapy and breast cancer, J. Natl. Cancer Inst. 90 (1998) 814-823.
    • (1998) J. Natl. Cancer Inst. , vol.90 , pp. 814-823
    • Colditz, G.1
  • 3
    • 0037501319 scopus 로고    scopus 로고
    • The estrogen receptor: A model for molecular medicine
    • E. Jensen, V. Jordan, The estrogen receptor: a model for molecular medicine, Clin. Cancer Res. 9 (2003) 1980-1989.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1980-1989
    • Jensen, E.1    Jordan, V.2
  • 4
    • 77954169894 scopus 로고    scopus 로고
    • Tissue-selective estrogen complexes: A promising option for the comprehensive management of menopausal symptoms
    • D. Archer, Tissue-selective estrogen complexes: a promising option for the comprehensive management of menopausal symptoms, Drugs Aging 27 (2010) 533-544.
    • (2010) Drugs Aging , vol.27 , pp. 533-544
    • Archer, D.1
  • 5
    • 67649574704 scopus 로고    scopus 로고
    • Designing the ideal selective estrogen receptor modulator: An achievable goal?
    • H. Taylor, Designing the ideal selective estrogen receptor modulator: an achievable goal?, Menopause 16 (2009) 609-615.
    • (2009) Menopause , vol.16 , pp. 609-615
    • Taylor, H.1
  • 6
    • 0008190079 scopus 로고    scopus 로고
    • Development of high throughput screening assays using fluorescence polarization: Nuclear receptor-ligand-binding and kinase/phosphatase assays
    • G. Parker, T. Law, F. Lenoch, R. Bolger, Development of high throughput screening assays using fluorescence polarization: nuclear receptor-ligand- binding and kinase/phosphatase assays, J. Biomol. Screen. 5 (2000) 77-88.
    • (2000) J. Biomol. Screen. , vol.5 , pp. 77-88
    • Parker, G.1    Law, T.2    Lenoch, F.3    Bolger, R.4
  • 7
    • 19344375930 scopus 로고    scopus 로고
    • Lanthanide-based luminescent assays for ligand-receptor interactions
    • DOI 10.1016/j.lfs.2005.01.009, PII S0024320505001876
    • H. Handl, R. Gillies, Lanthanide-based luminescent assays for ligand-receptor interactions, Life Sci. 77 (2005) 361-371. (Pubitemid 40719218)
    • (2005) Life Sciences , vol.77 , Issue.4 , pp. 361-371
    • Handl, H.L.1    Gillies, R.J.2
  • 9
    • 77949409085 scopus 로고    scopus 로고
    • A dual estrogen receptor TR-FRET assay for simultaneous measurement of steroid site binding and coactivator recruitment
    • T. Hilal, V. Puetter, C. Otto, K. Parczyk, B. Bader, A dual estrogen receptor TR-FRET assay for simultaneous measurement of steroid site binding and coactivator recruitment, J. Biomol. Screen. 15 (2010) 268-278.
    • (2010) J. Biomol. Screen. , vol.15 , pp. 268-278
    • Hilal, T.1    Puetter, V.2    Otto, C.3    Parczyk, K.4    Bader, B.5
  • 10
    • 46349085605 scopus 로고    scopus 로고
    • Development of a high-throughput cell-based assay for 11β-hydroxysteroid dehydrogenase type 1 using BacMam technology
    • D. Wang, Q. Lu, S. Walsh, L. Payne, S. Modha, M. Scott, T. Sweitzer, R. Ames, D. Krosky, H. Li, Development of a high-throughput cell-based assay for 11β-hydroxysteroid dehydrogenase type 1 using BacMam technology, Mol. Biotechnol. 39 (2008) 127-234.
    • (2008) Mol. Biotechnol. , vol.39 , pp. 127-234
    • Wang, D.1    Lu, Q.2    Walsh, S.3    Payne, L.4    Modha, S.5    Scott, M.6    Sweitzer, T.7    Ames, R.8    Krosky, D.9    Li, H.10
  • 11
    • 51949086073 scopus 로고    scopus 로고
    • Facile conversion of FP to TR-FRET assays using terbium chelates: Nuclear receptor competitive binding assays as examples
    • K. Vogel, B. Marks, K. Kupcho, K. Vedvik, T. Hallis, Facile conversion of FP to TR-FRET assays using terbium chelates: nuclear receptor competitive binding assays as examples, Lett. Drug Des. Discov. 5 (2008) 416-422.
    • (2008) Lett. Drug Des. Discov. , vol.5 , pp. 416-422
    • Vogel, K.1    Marks, B.2    Kupcho, K.3    Vedvik, K.4    Hallis, T.5
  • 14
    • 76149114604 scopus 로고    scopus 로고
    • Comparison of homogeneous single-label fluorometric binding assays: Fluorescence polarization and dual-parametric quenching resonance energy transfer technique
    • H. Härmä, G. Sarrail, J. Kirjavainen, E. Martikkala, I. Hemmilä, P. Hänninen, Comparison of homogeneous single-label fluorometric binding assays: fluorescence polarization and dual-parametric quenching resonance energy transfer technique, Anal. Chem. 82 (2010) 892-897.
    • (2010) Anal. Chem. , vol.82 , pp. 892-897
    • Härmä, H.1    Sarrail, G.2    Kirjavainen, J.3    Martikkala, E.4    Hemmilä, I.5    Hänninen, P.6
  • 16
    • 0028438492 scopus 로고
    • Synthesis of europium(III) chelates suitable for labeling of bioactive molecules
    • H. Takalo, V.M. Mukkala, H. Mikola, P. Liitti, I. Hemmilä, Synthesis of europium(III) chelates suitable for labeling of bioactive molecules, Bioconjug. Chem. 5 (1994) 278-282.
    • (1994) Bioconjug. Chem. , vol.5 , pp. 278-282
    • Takalo, H.1    Mukkala, V.M.2    Mikola, H.3    Liitti, P.4    Hemmilä, I.5
  • 17
    • 46349108126 scopus 로고    scopus 로고
    • Direct measure of fluorescence intensity for efficient receptor-binding assay: Conjugates of ethinylcarboxyestradiol and 5(and 6)-carboxyfluorescein via α,ω-diaminoalkanes as a tracer for estrogen receptor
    • DOI 10.1093/jb/mvn031
    • D. Asai, T. Tokunaga, K. Kondo, T. Kawaguchi, S. Takayanagi, T. Shinmyozu, M. Nakai, Y. Yakabe, Y. Shimohigashi, Direct measure of fluorescence intensity for efficient receptor-binding assay: conjugates of ethinylcarboxyestradiol 5(and 6)-carboxyfluorescein via α, ω-diaminoalkanes as a tracer for estrogen receptor, J. Biochem. 143 (2008) 781-792. (Pubitemid 351918940)
    • (2008) Journal of Biochemistry , vol.143 , Issue.6 , pp. 781-792
    • Asai, D.1    Tokunaga, T.2    Kondo, K.3    Kawaguchi, T.4    Takayanagi, S.5    Shinmyozu, T.6    Nakai, M.7    Yakabe, Y.8    Shimohigashi, Y.9
  • 18
    • 0025826785 scopus 로고
    • 17α-substituted analogs of estradiol for the development of fluorescent estrogen receptor ligands
    • M. Salman, B. Reddy, P. Delgado, P. Stotter, L. Fulcher, G. Chamness, 17α-substituted analogs of estradiol for the development of fluorescent estrogen receptor ligands, Steroids 56 (1991) 375-387.
    • (1991) Steroids , vol.56 , pp. 375-387
    • Salman, M.1    Reddy, B.2    Delgado, P.3    Stotter, P.4    Fulcher, L.5    Chamness, G.6
  • 19
    • 0031059270 scopus 로고    scopus 로고
    • The estradiol pharmacophore: Ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site
    • DOI 10.1016/S0039-128X(96)00242-5, PII S0039128X96002425
    • G. Anstead, K. Carlson, J. Katzenellenbogen, The estradiol pharmacophore: ligand structure-estrogen receptor binding affinity relationships and a model for the receptor binding site, Steroids 62 (1997) 268-303. (Pubitemid 27114399)
    • (1997) Steroids , vol.62 , Issue.3 , pp. 268-303
    • Anstead, G.M.1    Carlson, K.E.2    Katzenellenbogen, J.A.3
  • 21
    • 0036711669 scopus 로고    scopus 로고
    • Estrogen receptor binding assay method for endocrine disruptors using fluorescence polarization
    • K. Ohno, T. Fukushima, T. Santa, N. Waizumi, H. Tokuyama, M. Maeda, K. Imai, Estrogen receptor binding assay method for endocrine disruptors using fluorescence polarization, Anal. Chem. 74 (2002) 4391-4396.
    • (2002) Anal. Chem. , vol.74 , pp. 4391-4396
    • Ohno, K.1    Fukushima, T.2    Santa, T.3    Waizumi, N.4    Tokuyama, H.5    Maeda, M.6    Imai, K.7
  • 22
    • 0031039888 scopus 로고    scopus 로고
    • Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors and alpha and beta
    • DOI 10.1210/en.138.3.863
    • G. Kuiper, B. Carlsson, K. Grandien, E. Enmark, J. Häggblad, S. Nilsson, J. Gustafsson, Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta, Endocrinology 138 (1997) 863-870. (Pubitemid 27089735)
    • (1997) Endocrinology , vol.138 , Issue.3 , pp. 863-870
    • Kuiper, G.G.J.M.1    Carlsson, B.2    Grandien, K.3    Enmark, E.4    Haggblad, J.5    Nilsson, S.6    Gustafsson, J.-A.7
  • 23
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • J. Zhang, T. Chung, K. Oldenburg, A simple statistical parameter for use in evaluation and validation of high throughput screening assays, J. Biomol. Screen. 4 (1999) 67-73.
    • (1999) J. Biomol. Screen. , vol.4 , pp. 67-73
    • Zhang, J.1    Chung, T.2    Oldenburg, K.3
  • 24
    • 16544373673 scopus 로고    scopus 로고
    • Multiplexing fluorescence polarization assays to increase information content per screen: Applications for screening steroid hormone receptors
    • P. Blommel, G.T. Hanson, K.W. Vogel, Multiplexing fluorescence polarization assays to increase information content per screen: applications for screening steroid hormone receptors, J. Biomol. Screen. 9 (2004) 294-302.
    • (2004) J. Biomol. Screen. , vol.9 , pp. 294-302
    • Blommel, P.1    Hanson, G.T.2    Vogel, K.W.3
  • 25
    • 77950442251 scopus 로고    scopus 로고
    • Not picking pockets: Nuclear receptor alternate-site modulators (NRAMs) [minireview]
    • T. Moore, C. Mayne, J. Katzenellenbogen, Not picking pockets: nuclear receptor alternate-site modulators (NRAMs) [minireview], Mol. Endocrinol. 24 (2010) 683-695.
    • (2010) Mol. Endocrinol. , vol.24 , pp. 683-695
    • Moore, T.1    Mayne, C.2    Katzenellenbogen, J.3
  • 26
    • 77950795884 scopus 로고    scopus 로고
    • Monitoring a coordinated exchange process in a four-component biological interaction system: Development of a time-resolved terbium-based one-donor/three-acceptor multicolor FRET system
    • S. Kim, J. Gunther, J. Katzenellenbogen, Monitoring a coordinated exchange process in a four-component biological interaction system: development of a time-resolved terbium-based one-donor/three-acceptor multicolor FRET system, J. Am. Chem. Soc. 132 (2010) 4685-4692.
    • (2010) J. Am. Chem. Soc. , vol.132 , pp. 4685-4692
    • Kim, S.1    Gunther, J.2    Katzenellenbogen, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.