Overexpression of p27Kip1 lengthens the G1 phase in a mouse model that targets inducible gene expression to central nervous system progenitor cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 11, 2001, Pages 6435-6440

  Mitsuhashi, Takayuki ^a,b   Aoki, Yoko ^a,c   Eksioglu, Yaman Z ^a,d   Takahashi, Takao ^a,b   Bhide, Pradeep G ^a   Reeves, Steven A ^a   Caviness Jr , Verne S ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b KEIO UNIVERSITY   (Japan)

^c TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; PROTEIN P27; ANTIINFECTIVE AGENT; CDKN1B PROTEIN, MOUSE; CELL CYCLE PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; MICROTUBULE ASSOCIATED PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; EMBRYO; FEMALE; GENE EXPRESSION; GENE INDUCTION; GENE OVEREXPRESSION; GENE TARGETING; MOUSE; NEUROEPITHELIUM; NONHUMAN; PRIORITY JOURNAL; STEM CELL; TRANSGENE; TRANSGENIC MOUSE; ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; BIOSYNTHESIS; BRAIN CORTEX; CELL CYCLE; CYTOLOGY; DOSE RESPONSE; EPITHELIUM; GENETICS; METABOLISM; MITOSIS; NEOCORTEX; PHYSIOLOGY;

ANIMALIA; MAMMALIA; MUS MUSCULUS;

ANIMALS; ANTI-BACTERIAL AGENTS; APOPTOSIS; CELL CYCLE; CELL CYCLE PROTEINS; CENTRAL NERVOUS SYSTEM; CEREBRAL CORTEX; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXYCYCLINE; EPITHELIUM; G1 PHASE; GENE EXPRESSION; MICE; MICE, TRANSGENIC; MICROTUBULE-ASSOCIATED PROTEINS; MITOSIS; MODELS, BIOLOGICAL; NEOCORTEX; STEM CELLS; TRANSGENES; TUMOR SUPPRESSOR PROTEINS;

EID: 0035932804     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.111051398     Document Type: Article

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