-
1
-
-
2942514536
-
Increasing incidence rates of childhood malignant diseases in Sweden during the period 1960-1998
-
DOI 10.1016/j.ejca.2004.02.003, PII S0959804904001741
-
Dreifaldt AC, Carlberg M, Hardell L. Increasing incidence rates of childhood malignant diseases in Sweden during the period 1960-1998. Eur J Cancer 2004;40:1351-60 (Pubitemid 38737022)
-
(2004)
European Journal of Cancer
, vol.40
, Issue.9
, pp. 1351-1360
-
-
Dreifaldt, A.C.1
Carlberg, M.2
Hardell, L.3
-
2
-
-
0002557281
-
Medulloblastoma
-
Cavenee W, ed. Lyon, France: International Agency for Research on Cancer
-
Giangasparo FB, Kleihues P, Pietsch T, et al. Medulloblastoma. In: Cavenee W, ed. World Health Organization Classification of Tumors, Pathology and GeneticsVTumors of the Nervous System. Lyon, France: International Agency for Research on Cancer, 2000:129-39
-
(2000)
World Health Organization Classification of Tumors, Pathology and GeneticsVTumors of the Nervous System
, pp. 129-139
-
-
Giangasparo, F.B.1
Kleihues, P.2
Pietsch, T.3
-
3
-
-
0032796826
-
Sonic hedgehog regulates the growth and patterning of the cerebellum
-
Dahmane N, Ruizi Altaba A. Sonic hedgehog regulates the growth and patterning of the cerebellum. Development 1999;126:3089-100 (Pubitemid 29378174)
-
(1999)
Development
, vol.126
, Issue.14
, pp. 3089-3100
-
-
Dahmane, N.1
Ruiz I Altaba, A.2
-
4
-
-
0036146293
-
Sonic hedgehog signalling in the developing and adult brain
-
DOI 10.1016/S0928-4257(01)00075-4, PII S0928425701000754
-
Charytoniuk D, Porcel B, Rodriguez Gomez J, et al. Sonic Hedgehog signaling in the developing and adult brain. J Physiol 2002;96:9-16 (Pubitemid 34087028)
-
(2002)
Journal of Physiology Paris
, vol.96
, Issue.1-2
, pp. 9-16
-
-
Charytoniuk, D.1
Porcel, B.2
Rodriguez Gomez, J.3
Faure, H.4
Ruat, M.5
Traiffort, E.6
-
5
-
-
16144368562
-
Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly
-
Belloni E, Muenke M, Roessler E, et al. Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly. Nat Gen 1996;14: 353-56
-
(1996)
Nat Gen
, vol.14
, pp. 353-356
-
-
Belloni, E.1
Muenke, M.2
Roessler, E.3
-
6
-
-
15844381336
-
Human homolog of patched, a candidate gene for the basal cell nevus syndrome
-
Johnson RL, Rothman AL, Xie J, et al. Human homolog of patched, a candidate gene for the basal cell nevus syndrome. Science 1996;272: 1668-71 (Pubitemid 26200029)
-
(1996)
Science
, vol.272
, Issue.5268
, pp. 1668-1671
-
-
Johnson, R.L.1
Rothman, A.L.2
Xie, J.3
Goodrich, L.V.4
Bare, J.W.5
Bonifas, J.M.6
Quinn, A.G.7
Myers, R.M.8
Cox, D.R.9
Epstein Jr., E.H.10
Scott, M.P.11
-
8
-
-
33750007110
-
Patched homologue 1 mutations in four Japanese families with basal cell nevus syndrome
-
DOI 10.1136/jcp.2005.029439
-
Matsuzawa N, Nagao T, Shimozato K, et al. Patched homologue 1 mutations in four Japanese families with basal cell nevus syndrome. J Clin Pathol 2006;59:1084-86 (Pubitemid 44570332)
-
(2006)
Journal of Clinical Pathology
, vol.59
, Issue.10
, pp. 1084-1086
-
-
Matsuzawa, N.1
Nagao, T.2
Shimozato, K.3
Niikawa, N.4
Yoshiura, K.-I.5
-
9
-
-
32044471933
-
Contributions of PTCH gene variants to isolated cleft lip and palate
-
DOI 10.1597/04-169R.1
-
Mansilla MA, Cooper ME, Goldstein T, et al. Contributions of PTCH gene variants to isolated cleft lip and palate. Cleft Palate Craniofac J 2006;43:21-29 (Pubitemid 43201540)
-
(2006)
Cleft Palate-Craniofacial Journal
, vol.43
, Issue.1
, pp. 21-29
-
-
Mansilla, M.A.1
Cooper, M.E.2
Goldstein, T.3
Castilla, E.E.4
Lopez Camelo, J.S.5
Marazita, M.L.6
Murray, J.C.7
-
10
-
-
0345059765
-
Hedgehog signalling in cancer formation and maintenance
-
Pasca di Magliano M, Hebrok M. Hedgehog signaling in cancer formation and maintenance. Nat Rev 2003;3:903-11 (Pubitemid 37500175)
-
(2003)
Nature Reviews Cancer
, vol.3
, Issue.12
, pp. 903-911
-
-
Di Magliano, M.P.1
Hebrok, M.2
-
11
-
-
0036648241
-
Mutations in SUFU predispose to medulloblastoma
-
Taylor MD, Liu L, Raffel C, et al. Mutations in SUFU predispose to medulloblastoma. Nature Gen 2002;31:306-10
-
(2002)
Nature Gen
, vol.31
, pp. 306-310
-
-
Taylor, M.D.1
Liu, L.2
Raffel, C.3
-
12
-
-
0034493199
-
Molecular insight into medulloblastoma and central nervous system primitive neuroectodermal tumor biology from hereditary syndromes: A review
-
Taylor MD, Mainprize TG, Rutka JT. Molecular insight into medullo-blastoma and central nervous system primitive neuroectodermal tumor biology from hereditary syndromes: A review. Neurosurgery 2000;47: 888-901 (Pubitemid 32103665)
-
(2000)
Neurosurgery
, vol.47
, Issue.4
, pp. 888-901
-
-
Taylor, M.D.1
Mainprize, T.G.2
Rutka, J.T.3
-
13
-
-
0035001278
-
Activation of expression of hedgehog target genes in basal cell carcinomas
-
DOI 10.1046/j.1523-1747.2001.01315.x
-
Bonifas JM, Pennypacker S, Chuang PT, et al. Activation of expression of hedgehog target genes in basal cell carcinomas. J Invest Dermatol 2001;116:739-42 (Pubitemid 32467653)
-
(2001)
Journal of Investigative Dermatology
, vol.116
, Issue.5
, pp. 739-742
-
-
Bonifas, J.M.1
Pennypacker, S.2
Chuang, P.-T.3
McMahon, A.P.4
Williams, M.5
Rosenthal, A.6
De Sauvage, F.J.7
Epstein Jr., E.H.8
-
14
-
-
0037020216
-
Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched
-
Ma Y, Erkner A, Gong R, et al. Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell 2002;111:63-75
-
(2002)
Cell
, vol.111
, pp. 63-75
-
-
Ma, Y.1
Erkner, A.2
Gong, R.3
-
15
-
-
2942738996
-
The hedgehog response network: Sensors, switches, and routers
-
DOI 10.1126/science.1098020
-
Lum L, Beachy PA. The Hedgehog response network: Sensors, switches, and routers. Science 2004;304:1755-59 (Pubitemid 38787882)
-
(2004)
Science
, vol.304
, Issue.5678
, pp. 1755-1759
-
-
Lum, L.1
Beachy, P.A.2
-
17
-
-
0037155737
-
Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1
-
DOI 10.1016/S0092-8674(02)00664-5
-
Price MA, Kalderon D. Proteolysis of the Hedgehog signaling effector Cubitus interruptus requires phosphorylation by glycogen synthase kinase 3 and casein kinase 1. Cell 2002;108:823-35 (Pubitemid 34327533)
-
(2002)
Cell
, vol.108
, Issue.6
, pp. 823-835
-
-
Price, M.A.1
Kalderon, D.2
-
18
-
-
16344364134
-
Hedgehog signaling in normal urothelial cells and in urothelial carcinoma cell lines
-
DOI 10.1002/jcp.20248
-
Thievessen I, Wolter M, Prior A, et al. Hedgehog signaling in normal urothelial cells and in urothelial carcinoma cell lines. J Cell Physiol 2005; 203:372-77 (Pubitemid 40471771)
-
(2005)
Journal of Cellular Physiology
, vol.203
, Issue.2
, pp. 372-377
-
-
Thievessen, I.1
Wolter, M.2
Prior, A.3
Seifert, H.-H.4
Schulz, W.A.5
-
19
-
-
33646270662
-
Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation
-
Pan Y, Bai CB, Joyner AL, et al. Sonic hedgehog signaling regulates Gli2 transcriptional activity by suppressing its processing and degradation. Mol Cell Biol 2006;26:3365-77
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3365-3377
-
-
Pan, Y.1
Bai, C.B.2
Joyner, A.L.3
-
20
-
-
0033761448
-
Expression of the vertebrate GLI proteins in Drosophila reveals a distribution of activator and repressor activities
-
Aza-Blanc P, Lin HY, Ruizi Altaba A, et al. Expression of the vertebrate GLI proteins in Drosophila reveals a distribution of activator and repressor activities. Development 2000;127:4293-301
-
(2000)
Development
, vol.127
, pp. 4293-4301
-
-
Aza-Blanc, P.1
Lin, H.Y.2
Ruizi Altaba, A.3
-
21
-
-
33744536299
-
Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region
-
DOI 10.1242/dev.02339
-
Blaess S, Corrales JD, Joyner AL. Sonic hedgehog regulates GLI activator and repressor functions with spatial and temporal precision in the mid/hindbrain region. Development 2006;133:1799-809 (Pubitemid 43810986)
-
(2006)
Development
, vol.133
, Issue.9
, pp. 1799-1809
-
-
Blaess, S.1
Corrales, J.D.2
Joyner, A.L.3
-
22
-
-
0037111829
-
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity
-
DOI 10.1101/gad.243402
-
Persson M, Stamataki D, te Welscher P, et al. Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. Genes Develop 2002;16:2865-78 (Pubitemid 35334736)
-
(2002)
Genes and Development
, vol.16
, Issue.22
, pp. 2865-2878
-
-
Persson, M.1
Stamataki, D.2
Welscher, P.T.3
Andersson, E.4
Bose, J.5
Ruther, U.6
Ericson, J.7
Briscoe, J.8
-
23
-
-
0036490612
-
Focus on central nervous system neoplasia
-
DOI 10.1016/S1535-6108(02)00040-5
-
Louis DN, Pomeroy SL, Cairncross JG. Focus on central nervous system neoplasia. Cancer Cell 2002;1:125-28 (Pubitemid 41039158)
-
(2002)
Cancer Cell
, vol.1
, Issue.2
, pp. 125-128
-
-
Louis, D.N.1
Pomeroy, S.L.2
Cairncross, J.G.3
-
24
-
-
9344240453
-
A clinicobiological model predicting survival in medulloblastoma
-
DOI 10.1158/1078-0432.CCR-04-0499
-
Ray A, Ho M, Ma J, et al. A clinicobiological model predicting survival in medulloblastoma. Clin Cancer Res 2004;10:7613-20 (Pubitemid 39557524)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.22
, pp. 7613-7620
-
-
Ray, A.1
Ho, M.2
Ma, J.3
Parkes, R.K.4
Mainprize, T.G.5
Ueda, S.6
McLaughlin, J.7
Bouffet, E.8
Rutka, J.T.9
Hawkins, C.E.10
-
25
-
-
0035006794
-
Apoptosis, neuronal maturation, and neurotrophin expression within medulloblastoma nodules
-
Eberhart CG, Kaufman WE, Tihan T, Burger PC. Apoptosis, neuronal maturation, and neurotrophin expression within medulloblastoma nodules. J Neuropathol Exp Neurol 2001;60:462-69 (Pubitemid 32467103)
-
(2001)
Journal of Neuropathology and Experimental Neurology
, vol.60
, Issue.5
, pp. 462-469
-
-
Eberhart, C.G.1
Kaufman, W.E.2
Tihan, T.3
Burger, P.C.4
-
26
-
-
32944461718
-
Inhibition of GLI1 gene activation by Patched1
-
DOI 10.1042/BJ20050941
-
Rahnama F, Shimokawa T, Lauth M, et al. Inhibition of GLI1 gene activation by Patched1. Biochem J 2006;394:19-26 (Pubitemid 43259651)
-
(2006)
Biochemical Journal
, vol.394
, Issue.1
, pp. 19-26
-
-
Rahnama, F.1
Shimokawa, T.2
Lauth, M.3
Finta, C.4
Kogerman, P.5
Teglund, S.6
Toftgard, R.7
Zaphiropoulos, P.G.8
-
27
-
-
34248571816
-
Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells
-
DOI 10.1158/0008-5472.CAN-06-3040
-
Kim Y, Yoon JW, Xiao X, et al. Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells. Cancer Res 2007;67:3583-93 (Pubitemid 46762142)
-
(2007)
Cancer Research
, vol.67
, Issue.8
, pp. 3583-3593
-
-
Kim, Y.1
Joon, W.Y.2
Xiao, X.3
Dean, N.M.4
Monia, B.P.5
Marcusson, E.G.6
-
28
-
-
55849135600
-
Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans
-
Omenetti A, Porrello A, Jung Y, et al. Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans. J Clin Invest 2008;118:3331-42
-
(2008)
J Clin Invest
, vol.118
, pp. 3331-3342
-
-
Omenetti, A.1
Porrello, A.2
Jung, Y.3
-
29
-
-
2942618679
-
GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter
-
DOI 10.1111/j.0022-202X.2004.22612.x
-
Ikram MS, Neill GW, Regl G, et al. GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter. J Invest Dermatol 2004;122:1503-9 (Pubitemid 38757234)
-
(2004)
Journal of Investigative Dermatology
, vol.122
, Issue.6
, pp. 1503-1509
-
-
Ikram, M.S.1
Neill, G.W.2
Regl, G.3
Eichberger, T.4
Frischauf, A.-M.5
Aberger, F.6
Quinn, A.7
Philpott, M.8
-
30
-
-
34249867843
-
Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists
-
DOI 10.1073/pnas.0609699104
-
Lauth M, Bergstrom A, Shimokawa T, et al. Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists. Proc Natl Acad Sci USA 2007;104:8455-60 (Pubitemid 47175509)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.20
, pp. 8455-8460
-
-
Lauth, M.1
Bergstrom, A.2
Shimokawa, T.3
Toftgard, R.4
-
31
-
-
59449104701
-
Role of hedgehog signaling in ovarian cancer
-
Bhattacharya R, Kwon J, Ali B, et al. Role of hedgehog signaling in ovarian cancer. Clin Cancer Res 2008;14:7659-66
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7659-7666
-
-
Bhattacharya, R.1
Kwon, J.2
Ali, B.3
-
32
-
-
33847009559
-
Hedgehog signaling promotes medulloblastoma survival via BclII
-
DOI 10.2353/ajpath.2007.060066
-
Bar EE, Chaudhry A, Farah MH, et al. Hedgehog signaling promotes medulloblastoma survival via Bc/II. Am J Pathol 2007;170:347-55 (Pubitemid 47339212)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.1
, pp. 347-355
-
-
Bar, E.E.1
Chaudhry, A.2
Farah, M.H.3
Eberhart, C.G.4
-
34
-
-
49249089547
-
GLI1 induces G2/M arrest and apoptosis in hippocampal but not tumor-derived neural stem cells
-
Galvin KE, Ye H, Erstad DJ, et al. GLI1 induces G2/M arrest and apoptosis in hippocampal but not tumor-derived neural stem cells. Stem Cells 2008;26:1027-36
-
(2008)
Stem Cells
, vol.26
, pp. 1027-1036
-
-
Galvin, K.E.1
Ye, H.2
Erstad, D.J.3
-
35
-
-
0031679850
-
Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system
-
Matise MP, Epstein DJ, Park HL, et al. Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development 1998;125:2759-70 (Pubitemid 28410201)
-
(1998)
Development
, vol.125
, Issue.15
, pp. 2759-2770
-
-
Matise, M.P.1
Epstein, D.J.2
Park, H.L.3
Platt, K.A.4
Joyner, A.L.5
-
36
-
-
0031855859
-
Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice
-
Ding Q, Motoyama J, Gasca S, et al. Diminished sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development 1998;125:2533-43 (Pubitemid 28396152)
-
(1998)
Development
, vol.125
, Issue.14
, pp. 2533-2543
-
-
Ding, Q.1
Motoyama, J.2
Gasca, S.3
Mo, R.4
Sasaki, H.5
Rossant, J.6
Hui, C.-C.7
-
37
-
-
0036801765
-
Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway
-
Bai CB, Auerbach W, Lee JS, et al. GLI2, but not GLI1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development 2002;129:4753-61 (Pubitemid 35277202)
-
(2002)
Development
, vol.129
, Issue.20
, pp. 4753-4761
-
-
Bai, C.B.1
Auerbach, W.2
Lee, J.S.3
Stephen, D.4
Joyner, A.L.5
-
38
-
-
0034055649
-
Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation
-
Park HL, Bai C, Platt KA, et al. Mouse GLI1 mutants are viable but have defects in SHH signaling in combination with a GLI2 mutation. Development 2000;127:1593-605 (Pubitemid 30234917)
-
(2000)
Development
, vol.127
, Issue.8
, pp. 1593-1605
-
-
Park, H.L.1
Bai, C.2
Platt, K.A.3
Matise, M.P.4
Beeghly, A.5
Hui, C.C.6
Nakashima, M.7
Joyner, A.L.8
-
39
-
-
36349002459
-
Role of GLI2 transcription factor in growth and tumorigenicity of prostate cells
-
DOI 10.1158/0008-5472.CAN-07-2015
-
Thiyagarajan S, Bhatia N, Reagan-Shaw S, et al. Role of GLI2 transcription factor in growth and tumorigenicity of prostate cells. Cancer Res 2007;67:10642-46 (Pubitemid 350145887)
-
(2007)
Cancer Research
, vol.67
, Issue.22
, pp. 10642-10646
-
-
Thiyagarajan, S.1
Bhatia, N.2
Reagan-Shaw, S.3
Cozma, D.4
Thomas-Tikhonenko, A.5
Ahmad, N.6
Spiegelman, V.S.7
|