Interference of ribosomal frameshifting by antisense peptide nucleic acids suppresses SARS coronavirus replication

Antiviral Research

Volumn 91, Issue 1, 2011, Pages 1-10

  Ahn, Dae Gyun ^a   Lee, Wooseong ^a   Choi, Jin Kyu ^a   Kim, Seong Jun ^a   Plant, Ewan P ^b   Almazán, Fernando ^c   Taylor, Deborah R ^b   Enjuanes, Luis ^c   Oh, Jong Won ^a  

^a Yonsei University   (South Korea)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^c CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

Frameshifting; Peptide nucleic acids; RNA replication; SARS CoV

Indexed keywords

FIREFLY LUCIFERASE; PEPTIDE NUCLEIC ACID; VIRUS RNA;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INNATE IMMUNITY; NONHUMAN; PLASMID; PRIORITY JOURNAL; REPLICON; RIBOSOMAL FRAMESHIFTING; RNA SEQUENCE; SARS CORONAVIRUS; VIRUS INHIBITION; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; CELL LINE; CELL-PENETRATING PEPTIDES; CRICETINAE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FRAMESHIFTING, RIBOSOMAL; GENES, OVERLAPPING; GENES, REPORTER; GENOME, VIRAL; HUMANS; INTERFERON TYPE I; LUCIFERASES, FIREFLY; OLIGORIBONUCLEOTIDES, ANTISENSE; OPEN READING FRAMES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA REPLICASE; RNA, VIRAL; SARS VIRUS; VIRUS REPLICATION;

EUKARYOTA; RNA VIRUSES; SARS CORONAVIRUS;

EID: 79957473097     PISSN: 01663542     EISSN: 18729096     Source Type: Journal    
DOI: 10.1016/j.antiviral.2011.04.009     Document Type: Article

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