Further evidence for chemopreventive potential of β-carotene against experimental carcinogenesis: Diethylnitrosamine-initiated and phenobarbital-promoted hepatocarcinogenesis is prevented more effectively by β-carotene than by retinoic acid

Nutrition and Cancer

Volumn 37, Issue 1, 2000, Pages 89-98

  Bishayee, A ^a   Sarkar, A ^a   Chatterjee, M ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CAROTENE; CYTOCHROME P450; DIETHYLNITROSAMINE; GLUTATHIONE TRANSFERASE; PHENOBARBITAL; RETINOIC ACID; RETINOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER PREVENTION; CONTROLLED STUDY; DETOXIFICATION; ENZYME ACTIVITY; LIVER CARCINOGENESIS; MALE; NONHUMAN; RAT; XENOBIOTIC METABOLISM;

ANIMALIA;

EID: 0033839715     PISSN: 01635581     EISSN: None     Source Type: Journal    
DOI: 10.1207/S15327914NC3701_12     Document Type: Article

References (67)

1. Tissue changes following deprivation of fat-soluble vitamin
2. Retinoids block phenotypic cell transformation produced by sarcoma growth factor
3. Reversible inhibition by retinoids of 3-methylcholanthrene-induced neoplastic transformation in C3H10T1/ 2 cells
4. Therapeutic effects of an aromatic retinoic acid analogue on chemically induced skin papillomas and carcinomas of mice
5. Inhibition of growth and regression of a transplantable rat chondrosarcoma by three retinoids
6. Retinoic acid inhibition of human breast carcinoma proliferation is accompanied by inhibition of the synthesis of M(r) 39,000 protein
7. Retinoids in cancer therapy
8. Inhibition of 4-nitroquinoline-1-oxide-induced rat oral carcinogenesis by dietary exposure of new retinoidal butenolide, KYN-54, during the initiation and post-initiation phases
9. Antitumor activity of a novel synthetic polyprenoic acid (E-5166) on 'spontaneous' hepatic tumors of C3H/HeNCrj mice
10. Inhibitory effects of polyprenoic acid (E-5166) on N-2-fluorenylacetamide-initiated hepatocarcinogenesis in rats
11. Inhibitory effects of synthetic acidic retinoid and polyprenoic acid on the development of hepatoma in rats induced by 3'-methyl-N,N-dimethyl-4-aminoazobenzene
12. Vitamin A, E and carotene: Effect of supplementation on their plasma levels
13. Vitamin A, carotenoids and retinoids
14. Biological actions of carotenoids
15. Protective effect of β-carotene against colon tumors in mice
16. Carotenoids and cancer in animal models
17. Inhibitory effect of dietary β-carotene during chronic 2-acetylaminofluorene induced hepatocarcinogenesis in rat: Reflection in hepatic drug metabolism
18. Inhibition of 3'-methyl-4-dimethylaminoazobenzene induced hepatocarcinogenesis in rat by dietary β-carotene: Changes in the hepatic antioxidant defence enzyme levels
19. β-Carotene inhibits lipid peroxidation and red blood cell membrane protein damage in experimental hepatocarcinogenesis
20. Intermediate cancer biomarkers and their use in β-carotene studies in humans
21. Carotenoids and cancer: An update with emphasis on human intervention studies
22. The sequential analysis of liver cancer induction
23. Glutathione transferases as markers of preneoplasia and neoplasia
24. Inhibitory effect of vanadium on rat liver carcinogenesis initiated with diethylnitrosamine and promoted by phenobarbital
25. Glutathione and γ-glutamyl transferase in rat liver during chemical carcinogenesis
26. γ-Glutamyl transferase in putative premalignant liver cell populations during carcinogenesis
27. Glutathione peroxidase activity in selenium-deficient rat liver
28. The carbon monoxide-binding pigment of liver microsomes
29. Glutathione S-transferase: The first enzymatic step in mercapturic acid formation
30. A simple dual assay of vitamin A and carotenoids in human liver
31. Protein measurement with Folin phenol reagent
32. Inhibitory effect of β-carotene on preneoplastic lesions induced in Wistar rats by the resistant hepatocyte model
33. A comparison of β-carotene and vitamin A effects on a hepatocarcinogenesis model
34. Chemopreventive effects of β-carotene, α-tocopherol, and five naturally occurring antioxidants on initiation of hepatocarcinogenesis by 2-amino-3-methylimidazo[4,5-f]quinone in the rat
35. Clonal adaptation during carcinogenesis
36. No evidence for an inhibitory effect of β-carotene or of canthaxanthin on the initiation of liver preneoplastic foci by diethylnitrosamine in the rat
37. Dietary lycopene decreases the initiation of liver preneoplastic foci by diethylnitrosamine in the rat
38. Inhibition of altered liver cell foci and persistent nodule growth by vanadium during diethylnitrosamine-induced hepatocarcinogenesis in rats
39. 2-Induced DNA single strand breaks are inhibited by antioxidative vitamins in V79 cells
40. Carotenoids protect against cell membrane damage by nitrogen dioxide radical
41. Feeding mice palm carotene prevents DNA damage in bone marrow and reduction of peripheral leukocyte counts and enhances survival following X-ray irradiation
42. Effects of dietary anticarcinogens on rat gastrointestinal glutathione peroxidase activity
43. Rat liver epithelial cells express functional cytochrome P450 2E1
44. Characterization of selective induction and alteration of xenobiotic biotransforming enzymes by vanadium during diethylnitrosamine-induced chemical rat liver carcinogenesis
45. 1- and N-nitrosodiethylamine-induced liver preneoplastic foci in rats fed naturally occurring allyl sulfides
46. Effect of dietary β-carotene on hepatic drug-metabolizing enzymes in mice
47. Alterations in β-carotene and vitamin E status in rats fed β-carotene and vitamin A
48. Effects of β-carotene and canthaxanthin on liver xenobiotic-metabolizing enzymes in the rat
49. 1 metabolism
50. Chemoprevention by inducers of carcinogen detoxification enzymes
51. β-Carotene inhibits rat liver chromosomal aberrations and DNA chain break after a single injection of diethylnitrosamine
52. Cell-cell communication in carcinogenesis
53. Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H10T1/2 cells: Relationship to their cancer chemopreventive action
54. Enhancement of gap junctional communication by retinoids correlates with their ability to inhibit neoplastic transformation
55. Carotenoids up-regulate connexin-43 gene expression independent of their provitamin A or antioxidant properties
56. Retinoid-enhanced gap junctional communication is achieved by increased levels of connexin-43 mRNA and protein
57. Carotenoids and the immune function
58. The effect of vitamin E and β-carotene on the incidence of lung cancer and other cancers in male smokers
59. β-Carotene and lung cancer: A case study
60. β-Carotene and cancer chemoprevention
61. Whatever happened to β-carotene?
62. β-Carotene and the prevention of cancer
63. Prevention of second primary tumors with isotretionin in squamous cell carcinoma of the head and neck
64. All-trans retinoic acid as a differentiation therapy of acute promyelocytic leukemia. I. Clinical results
65. Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma
66. Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma
67. Pharmacokinetics of oral all-trans retinoic acid in patients with acute promyelocytic leukemia