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Volumn 135, Issue 5, 2011, Pages 578-587

Molecular diagnostics of colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

B RAF KINASE; BRAF PROTEIN, HUMAN; KRAS PROTEIN, HUMAN; ONCOPROTEIN; RAS PROTEIN; TUMOR MARKER;

EID: 79956359425     PISSN: 00039985     EISSN: 15432165     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (48)

References (79)
  • 2
    • 0029066689 scopus 로고
    • Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
    • Markowitz S, Wang J, Myeroff L, et al. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. Science. 1995; 268 (5215): 1336-1338.
    • (1995) Science , vol.268 , Issue.5215 , pp. 1336-1338
    • Markowitz, S.1    Wang, J.2    Myeroff, L.3
  • 3
    • 0031018674 scopus 로고    scopus 로고
    • Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
    • DOI 10.1126/science.275.5302.967
    • Rampino N, Yamamoto H, lonov Y, et al. Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype. Science. 1997; 275 (5302): 967-969. (Pubitemid 27087710)
    • (1997) Science , vol.275 , Issue.5302 , pp. 967-969
    • Rampino, N.1    Yamamoto, H.2    Ionov, Y.3    Li, Y.4    Sawai, H.5    Reed, J.C.6    Perucho, M.7
  • 4
    • 0037390446 scopus 로고    scopus 로고
    • The hereditary nonpolyposis colorectal cancer syndrome: Genetics and clinical implications
    • Chung DC, Rustgi AK. The hereditary nonpolyposis colorectal cancer syndrome: genetics and clinical implications. Ann Intern Med. 2003;138(7):560-570.
    • (2003) Ann Intern Med. , vol.138 , Issue.7 , pp. 560-570
    • Chung, D.C.1    Rustgi, A.K.2
  • 5
    • 0033557898 scopus 로고    scopus 로고
    • Recognition of DNA alterations by the mismatch repair system
    • DOI 10.1042/0264-6021:3380001
    • Marra G, Schar P. Recognition of DNA alterations by the mismatch repair system. Biochem J. 1999;338(pt 1):1-13. (Pubitemid 29097278)
    • (1999) Biochemical Journal , vol.338 , Issue.1 , pp. 1-13
    • Marra, G.1    Schar, P.2
  • 6
    • 17944362664 scopus 로고    scopus 로고
    • Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer)
    • Hampel H, Frankel WL, Martin E, et al. Screening for the Lynch syndrome (hereditary nonpolyposis colorectal cancer). N Engl J Med. 2005; 352(18):1851-1860.
    • (2005) N Engl J Med. , vol.352 , Issue.18 , pp. 1851-1860
    • Hampel, H.1    Frankel, W.L.2    Martin, E.3
  • 8
    • 0032730774 scopus 로고    scopus 로고
    • Genetic susceptibility to non-polyposis colorectal cancer
    • Lynch HT, de la Chapelle A. Genetic susceptibility to non-polyposis colorectal cancer.; Med Genet. 1999; 36(11):801-818. (Pubitemid 29520569)
    • (1999) Journal of Medical Genetics , vol.36 , Issue.11 , pp. 801-818
    • Lynch, H.T.1    De La Chapelle, A.2
  • 9
    • 4544310802 scopus 로고    scopus 로고
    • Mutations associated with HNPCC predisposition - Update of ICG-HNPCC/INSiGHT mutation database
    • Lynch Syndrome (HNPCC) and Microsatellite Instability
    • Peltomäki P, Vasen H. Mutations associated with HNPCC predispositionupdate of ICG-HNPCC/INSiGHT mutation database. Dis Markers. 2004;20(4-5): 269-276. (Pubitemid 40164099)
    • (2004) Disease Markers , vol.20 , Issue.4-5 , pp. 269-276
    • Peltomaki, P.1    Vasen, H.2
  • 11
    • 0033063711 scopus 로고    scopus 로고
    • New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative Group on HNPCC
    • DOI 10.1016/S0016-5085(99)70510-X
    • Vasen HF, Watson P, Mecklin JP, Lynch HT. New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative Group on HNPCC. Gastroenterology. 1999; 116(6): 1453-1456. (Pubitemid 29258894)
    • (1999) Gastroenterology , vol.116 , Issue.6 , pp. 1453-1456
    • Vasen, H.F.A.1    Watson, P.2    Mecklin, J.-P.3    Lynch, H.T.4
  • 12
    • 0027467494 scopus 로고
    • Extracolonic cancer in hereditary nonpolyposis colorectal cancer
    • DOI 10.1002/1097-0142(19930201)71:3<677::AID-CNCR2820710305>3.0. CO;2-#
    • Watson P, Lynch HT. Extracolonic cancer in hereditary nonpolyposis colorectal cancer. Cancer. 1993; 71(3):677-685. (Pubitemid 23051366)
    • (1993) Cancer , vol.71 , Issue.3 , pp. 677-685
    • Watson, P.1    Lynch, H.T.2
  • 13
    • 0028152314 scopus 로고
    • Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer
    • Hemminki A, Peltomäki P, Mecklin JP, et al. Loss of the wild type MLH1 gene is a feature of hereditary nonpolyposis colorectal cancer. Nat Genet. 1994; 8(4):405-410.
    • (1994) Nat Genet. , vol.8 , Issue.4 , pp. 405-410
    • Hemminki, A.1    Peltomäki, P.2    Mecklin, J.P.3
  • 14
    • 0028572431 scopus 로고
    • Accumulation of multiple mutations in tumour suppressor genes during colorectal tumorigenesis in HNPCC patients
    • Lazar V, Grandjouan S, Bognel C, et al. Accumulation of multiple mutations in tumour suppressor genes during colorectal tumorigenesis in HNPCC patients. Hum Mol Genet 1994; 3(12): 2257-2260.
    • (1994) Hum Mol Genet , vol.3 , Issue.12 , pp. 2257-2260
    • Lazar, V.1    Grandjouan, S.2    Bognel, C.3
  • 15
    • 0021952377 scopus 로고
    • Hereditary nonpolyposis colorectal cancer in a Navajo Indian family
    • DOI 10.1016/0165-4608(85)90164-5
    • Lynch HT, Drouhard TJ, Schuelke GS, Biscone KA, Lynch JF, Danes BS. Hereditary nonpolyposis colorectal cancer in a Navajo Indian family. Cancer Genet Cytogenet. 1985; 15(3-4): 209-213. (Pubitemid 15140843)
    • (1985) Cancer Genetics and Cytogenetics , vol.15 , Issue.3-4 , pp. 209-213
    • Lynch, H.T.1    Drouhard, T.J.2    Schuelke, G.S.3
  • 16
    • 0022978562 scopus 로고
    • Histopathology of colorectal carcinomas and adenomas in cancer family syndrome
    • DOI 10.1007/BF02555362
    • Mecklin JP, Sipponen P, Jarvinen HJ. Histopathology of colorectal carcinomas and adenomas in cancer family syndrome. Dis Colon Rectum. 1986, 29(12):849-853. (Pubitemid 17208885)
    • (1986) Diseases of the Colon and Rectum , vol.29 , Issue.12 , pp. 849-853
    • Mecklin, J.-P.1    Sipponen, P.2    Jarvinen, H.J.3
  • 17
    • 24044540727 scopus 로고    scopus 로고
    • Loss of mismatch repair protein immunostaining in colorectal adenomas from patients with hereditary nonpolyposis colorectal cancer
    • Halvarsson B, Lindblom A, Johansson L, Lagerstedt K, Nilbert M. Loss of mismatch repair protein immunostaining in colorectal adenomas from patients with hereditary nonpolyposis colorectal cancer. Mod Pathol. 2005;18(81:1095-1101.
    • (2005) Mod Pathol. , vol.18-81 , pp. 1095-1101
    • Halvarsson, B.1    Lindblom, A.2    Johansson, L.3    Lagerstedt, K.4    Nilbert, M.5
  • 18
    • 0029005780 scopus 로고
    • Interval cancers in hereditary nonpolyposis colorectal cancer (Lynch syndrome)
    • Vasen HF, Nagengast FM, Khan PM. Interval cancers in hereditary nonpolyposis colorectal cancer (Lynch syndrome). Lancet. 1995; 345(8958):1183- 1184.
    • (1995) Lancet , vol.345 , Issue.8958 , pp. 1183-1184
    • Vasen, H.F.1    Nagengast, F.M.2    Khan, P.M.3
  • 20
    • 0028276666 scopus 로고
    • Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
    • Kim H, Jen J, Vogelstein B, Hamilton SR. Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am J Pathol. 1994:145(1):148-156. (Pubitemid 24217493)
    • (1994) American Journal of Pathology , vol.145 , Issue.1 , pp. 148-156
    • Kim, H.1    Jen, J.2    Vogelstein, B.3    Hamilton, S.R.4
  • 22
    • 0031017268 scopus 로고    scopus 로고
    • Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines
    • Kane MF, Loda M, Gaida GM, et al. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res. 1997;57(5):808-811. (Pubitemid 27097998)
    • (1997) Cancer Research , vol.57 , Issue.5 , pp. 808-811
    • Kane, M.F.1    Loda, M.2    Gaida, G.M.3    Lipman, J.4    Mishra, R.5    Goldman, H.6    Jessup, J.M.7    Kolodner, R.8
  • 23
    • 0027285475 scopus 로고
    • Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
    • lonov Y, Peinado MA, Malkhosyan S, Shibata D, Perucho M. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature. 1993; 363(6429):558-561.
    • (1993) Nature , vol.363 , Issue.6429 , pp. 558-561
    • Lonov, Y.1    Peinado, M.A.2    Malkhosyan, S.3    Shibata, D.4    Perucho, M.5
  • 24
    • 24144491263 scopus 로고    scopus 로고
    • Serrated polyps of the large intestine: A morphologic and molecular review of an evolving concept
    • DOI 10.1309/V2EP-TPLJ-RB3F-GHJL
    • Snover DC, Jass JR, Fenoglio-Preiser C, Batts KP. Serrated polyps of the large intestine: a morphologic and molecular review of an evolving concept. Am J Clin Pathol. 2005; 124(3):380-391. (Pubitemid 41232924)
    • (2005) American Journal of Clinical Pathology , vol.124 , Issue.3 , pp. 380-391
    • Snover, D.C.1    Jass, J.R.2    Fenoglio-Preiser, C.3    Batts, K.P.4
  • 29
    • 33745181120 scopus 로고    scopus 로고
    • Histologic features distinguish microsatellite-high from microsatellite-low and microsatellite-stable colorectal carcinomas, but do not differentiate germline mutations from methylation of the MLH1 promoter
    • Yearsley M, Hampel H, Lehman A, Nakagawa H, de la Chapelle A, Frankel WL. Histologic features distinguish microsatellite-high from microsatellite-low and microsatellite-stable colorectal carcinomas, but do not differentiate germline mutations from methylation of the MLH1 promoter. Hum Pathol. 2006; 37(71:831-838.
    • (2006) Hum Pathol. , vol.37-71 , pp. 831-838
    • Yearsley, M.1    Hampel, H.2    Lehman, A.3    Nakagawa, H.4    De La Chapelle, A.5    Frankel, W.L.6
  • 30
    • 0032534069 scopus 로고    scopus 로고
    • A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
    • Boland CR, Thibodeau SN, Hamilton SR, et al. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res. 1998; 58(22):5248-5257.
    • (1998) Cancer Res. , vol.58 , Issue.22 , pp. 5248-5257
    • Boland, C.R.1    Thibodeau, S.N.2    Hamilton, S.R.3
  • 35
    • 33646918038 scopus 로고    scopus 로고
    • The genetics of HNPCC: Application to diagnosis and screening
    • DOI 10.1016/j.critrevonc.2005.11.001, PII S1040842805002258
    • Abdel-Rahman WM, Mecklin JP, Peltomäki P. The genetics of HNPCC: application to diagnosis and screening. Crit Rev Oncol Hematol. 2006;58(3): 208-220. (Pubitemid 43796078)
    • (2006) Critical Reviews in Oncology/Hematology , vol.58 , Issue.3 , pp. 208-220
    • Abdel-Rahman, W.M.1    Mecklin, J.-P.2    Peltomaki, P.3
  • 38
    • 77954784170 scopus 로고    scopus 로고
    • Immunohistochemistry for PMS2 and MSH6 alone can replace a four antibody panel for mismatch repair deficiency screening in colorectal adenocarcinoma
    • Hall G, Clarkson A, Shi A, et al. Immunohistochemistry for PMS2 and MSH6 alone can replace a four antibody panel for mismatch repair deficiency screening in colorectal adenocarcinoma. Pathology. 2010; 42(5):409-413.
    • (2010) Pathology , vol.42 , Issue.5 , pp. 409-413
    • Hall, G.1    Clarkson, A.2    Shi, A.3
  • 39
    • 70350437372 scopus 로고    scopus 로고
    • Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: A 2-antibody panel may be as predictive as a 4-antibody panel
    • Shia J, Tang LH, Vakiani E, et al. Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panel. Am J Surg Pathol. 2009.
    • (2009) Am J Surg Pathol.
    • Shia, J.1    Tang, L.H.2    Vakiani, E.3
  • 43
    • 47649101956 scopus 로고    scopus 로고
    • Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: Part II. The utility of microsatellite instability testing
    • DOI 10.2353/jmoldx.2008.080062
    • Zhang L. Immunohistochemistry versus microsatellite instability testing for screening colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome, part II: the utility of microsatellite instability testing. J Mol Diagn. 2008; 10(4):301-307. (Pubitemid 352019114)
    • (2008) Journal of Molecular Diagnostics , vol.10 , Issue.4 , pp. 301-307
    • Zhang, L.1
  • 45
    • 73949154143 scopus 로고    scopus 로고
    • Colorectal cancer due to deficiency in DNA mismatch repair function: A review
    • Bellizzi AM, Frankel WL. Colorectal cancer due to deficiency in DNA mismatch repair function: a review. Adv Anat Pathol. 2009; 16(6): 405-417.
    • (2009) Adv Anat Pathol. , vol.16 , Issue.6 , pp. 405-417
    • Bellizzi, A.M.1    Frankel, W.L.2
  • 47
    • 0031551963 scopus 로고    scopus 로고
    • A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: Meeting highlights and Bethesda guidelines
    • Rodriguez-Bigas MA, Boland CR, Hamilton SR, et al. A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: meeting highlights and Bethesda guidelines. J Natl Cancer Inst. 1997;89(23): 1758-1762.
    • (1997) J Natl Cancer Inst. , vol.89 , Issue.23 , pp. 1758-1762
    • Rodriguez-Bigas, M.A.1    Boland, C.R.2    Hamilton, S.R.3
  • 49
    • 0035912144 scopus 로고    scopus 로고
    • Molecular predictors of survival after adjuvant chemotherapy for colon cancer
    • Watanabe T, Wu TT, Catalano PJ, et al. Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med. 2001,-344(16): 1196-1206.
    • (2001) N Engl J Med. , vol.344 , Issue.16 , pp. 1196-1206
    • Watanabe, T.1    Wu, T.T.2    Catalano, P.J.3
  • 50
    • 58249089525 scopus 로고    scopus 로고
    • CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer
    • Ogino S, Nosho K, Kirkner GJ, et al. CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. Gut. 2009;58(1):90-96.
    • (2009) Gut. , vol.58 , Issue.1 , pp. 90-96
    • Ogino, S.1    Nosho, K.2    Kirkner, G.J.3
  • 53
    • 0025848680 scopus 로고
    • The international collaborative group on hereditary non-polyposis colorectal cancer (ICGHNPCC)
    • Vasen HF, Mecklin JP, Khan PM, Lynch HT. The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICGHNPCC). Dis Colon Rectum. 1991; 34(5):424-425.
    • (1991) Dis Colon Rectum. , vol.34 , Issue.5 , pp. 424-425
    • Vasen, H.F.1    Mecklin, J.P.2    Khan, P.M.3    Lynch, H.T.4
  • 56
    • 57449097359 scopus 로고    scopus 로고
    • Feasibility of screening for Lynch syndrome among patients with colorectal cancer
    • Hampel H, Frankel WL, Martin E, et al. Feasibility of screening for Lynch syndrome among patients with colorectal cancer. J Clin Oncol. 2008, 26(35): 5783-5788.
    • (2008) J Clin Oncol. , vol.26 , Issue.35 , pp. 5783-5788
    • Hampel, H.1    Frankel, W.L.2    Martin, E.3
  • 57
    • 55349099844 scopus 로고    scopus 로고
    • Identification in daily practice of patients with Lynch syndrome (hereditary nonpolyposis colorectal cancer): Revised Bethesda guidelines-based approach versus molecular screening
    • [quiz in Am J Gastroenterol. 2008;103(11):2836]
    • Julie C, Tresallet C, Brouquet A, et al. Identification in daily practice of patients with Lynch syndrome (hereditary nonpolyposis colorectal cancer): revised Bethesda guidelines-based approach versus molecular screening [quiz in Am J Gastroenterol. 2008;103(11):2836]. Am J Gastroenterol. 2008; 103(11): 2825-2835.
    • (2008) Am J Gastroenterol. , vol.103 , Issue.11 , pp. 2825-2835
    • Julie, C.1    Tresallet, C.2    Brouquet, A.3
  • 58
    • 59849108362 scopus 로고    scopus 로고
    • Recommendations from the EGAPP Working Group: Genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives
    • Berg AO. Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives. Genet Med. 2009; 11(1): 35-41.
    • (2009) Genet Med. , vol.11 , Issue.1 , pp. 35-41
    • Berg, A.O.1
  • 59
    • 2142641698 scopus 로고    scopus 로고
    • Phase II trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor
    • DOI 10.1200/JCO.2004.10.182
    • Saltz LB, Meropol NJ, Loehrer PJ Sr, Needle MN, Kopit J, Mayer RJ. Phase Il trial of cetuximab in patients with refractory colorectal cancer that expresses the epidermal growth factor receptor. J Clin Oncol. 2004; 22(7): 1201-1208. (Pubitemid 41079832)
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.7 , pp. 1201-1208
    • Saltz, L.B.1    Meropol, N.J.2    Loehrer Sr., P.J.3    Needle, M.N.4    Kopit, J.5    Mayer, R.J.6
  • 60
    • 42649145667 scopus 로고    scopus 로고
    • Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer
    • Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol. 2008; 26(10): 1626-1634.
    • (2008) J Clin Oncol. , vol.26 , Issue.10 , pp. 1626-1634
    • Amado, R.G.1    Wolf, M.2    Peeters, M.3
  • 63
    • 54949085398 scopus 로고    scopus 로고
    • K-ras mutations and benefit from cetuximab in advanced colorectal cancer
    • Karapetis CS, Khambata-Ford S, Jonker DJ, et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med. 2008; 359(17): 1757-1765.
    • (2008) N Engl J Med. , vol.359 , Issue.17 , pp. 1757-1765
    • Karapetis, C.S.1    Khambata-Ford, S.2    Jonker, D.J.3
  • 65
    • 33646228635 scopus 로고    scopus 로고
    • KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer
    • Lièvre A, Bachet JB, Le Corre D, et al. KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. Cancer Res. 2006;66(8): 3992-3995.
    • (2006) Cancer Res. , vol.66 , Issue.8 , pp. 3992-3995
    • Lièvre, A.1    Bachet, J.B.2    Le Corre, D.3
  • 66
    • 65349189958 scopus 로고    scopus 로고
    • American Society of Clinical Oncology provisional clinical opinion: Testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to antiepidermal growth factor receptor monoclonal antibody therapy
    • Allegra CJ, Jessup JM, Somerfield MR, et al. American Society of Clinical Oncology provisional clinical opinion: testing for KRAS gene mutations in patients with metastatic colorectal carcinoma to predict response to antiepidermal growth factor receptor monoclonal antibody therapy. J Clin Oncol. 2009; 27(12): 2091-2096.
    • (2009) J Clin Oncol. , vol.27 , Issue.12 , pp. 2091-2096
    • Allegra, C.J.1    Jessup, J.M.2    Somerfield, M.R.3
  • 67
    • 79956370638 scopus 로고    scopus 로고
    • Members NCCP. Network NCC, eds. Fort Washington, PA: NCCN publication
    • Members NCCP. NCCN Clinical Practice Guidelines in Oncology-Colon Cancer. In: Network NCC, eds. Vol 4. Fort Washington, PA: NCCN publication; 2008.
    • (2008) NCCN Clinical Practice Guidelines in Oncology-Colon Cancer , vol.4
  • 70
  • 71
    • 57449095367 scopus 로고    scopus 로고
    • Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
    • Di Nicolantonio F, Martini M, Molinari F, et al. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol. 2008; 26(35):5705-5712.
    • (2008) J Clin Oncol. , vol.26 , Issue.35 , pp. 5705-5712
    • Di Nicolantonio, F.1    Martini, M.2    Molinari, F.3
  • 72
    • 68749119351 scopus 로고    scopus 로고
    • KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer
    • Loupakis F, Ruzzo A, Cremolini C, et al. KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer. Br J Cancer. 2009,101 (41:715-721.
    • (2009) Br J Cancer. , vol.101 , Issue.41 , pp. 715-721
    • Loupakis, F.1    Ruzzo, A.2    Cremolini, C.3
  • 73
    • 33751165545 scopus 로고    scopus 로고
    • Recurrent KRAS codon 146 mutations in human colorectal cancer
    • Edkins S, O'Meara S, Parker A, et al. Recurrent KRAS codon 146 mutations in human colorectal cancer. Cancer Biol Ther. 2006;5(8):928-932.
    • (2006) Cancer Biol Ther. , vol.5 , Issue.8 , pp. 928-932
    • Edkins, S.1    O'Meara, S.2    Parker, A.3
  • 74
    • 77955277111 scopus 로고    scopus 로고
    • Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: A retrospective consortium analysis
    • De Roock W, Claes B, Bernasconi D, et al. Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. Lancet Oncol. 2010; 11(8): 753-762.
    • (2010) Lancet Oncol. , vol.11 , Issue.8 , pp. 753-762
    • De Roock, W.1    Claes, B.2    Bernasconi, D.3
  • 76
    • 59049089201 scopus 로고    scopus 로고
    • PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients
    • Perrone F, Lampis A, Orsenigo M, et al. PI3KCA/PTEN deregulation contributes to impaired responses to cetuximab in metastatic colorectal cancer patients. Ann Oncol. 2009; 20(1):84-90.
    • (2009) Ann Oncol. , vol.20 , Issue.1 , pp. 84-90
    • Perrone, F.1    Lampis, A.2    Orsenigo, M.3
  • 78
    • 5444227865 scopus 로고    scopus 로고
    • Guilty as charged: B-RAF is a human oncogene
    • DOI 10.1016/j.ccr.2004.09.022, PII S153561080400279X
    • Garnett MJ, Marais R. Guilty as charged: B-RAF is a human oncogene. Cancer Cell. 2004; 6(4):313-319. (Pubitemid 39361432)
    • (2004) Cancer Cell , vol.6 , Issue.4 , pp. 313-319
    • Garnett, M.J.1    Marais, R.2
  • 79
    • 14644445166 scopus 로고    scopus 로고
    • Epidermal growth factor receptor signaling in colorectal cancer: Preclinical data and therapeutic perspectives
    • DOI 10.1093/annonc/mdi057
    • Spano JP, Fagard R, Soria JC, Rixe O, Khayat D, Milano G. Epidermal growth factor receptor signaling in colorectal cancer: preclinical data and therapeutic perspectives. Ann Oncol. 2005;16(2):189-194. (Pubitemid 40309295)
    • (2005) Annals of Oncology , vol.16 , Issue.2 , pp. 189-194
    • Spano, J.P.1    Fagard, R.2    Soria, J.-C.3    Rixe, O.4    Khayat, D.5    Milano, G.6


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