The strictly conserved Arg-321 residue in the active site of Escherichia coli topoisomerase I plays a critical role in DNA rejoining

Journal of Biological Chemistry

Volumn 286, Issue 21, 2011, Pages 18673-18680

  Narula, Gagandeep ^a   Annamalai, Thirunavukkarasu ^a   Aedo, Sandra ^a   Cheng, Bokun ^a   Sorokin, Elena ^a   Wong, Agnes ^a   Tse Dinh, Yuk Ching ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ANTIBACTERIAL DRUGS; ARGININE RESIDUE; BIOCHEMICAL ANALYSIS; DIVALENT METAL ION; DNA CLEAVAGE; E. COLI; ENZYME-DNA INTERACTIONS; GENETIC SCREENING; NUCLEOPHILIC ATTACK; PHOSPHOTYROSINE; PRECISE POSITIONING; RELAXATION ACTIVITIES; SIDE-CHAINS; SMALL MOLECULES; STRINGENT REQUIREMENT; SUPERCOILED DNA; TOPOISOMERASE I; TOPOISOMERASES; YERSINIA PESTIS;

ARGININE; DRUG INTERACTIONS; ENZYMES; ESCHERICHIA COLI; METAL IONS;

DNA;

ARGININE; BACTERIAL DNA; DNA TOPOISOMERASE; MAGNESIUM ION;

ARTICLE; BACTERIAL STRAIN; CONTROLLED STUDY; DNA CLEAVAGE; DNA REJOINING; ENZYME ACTIVE SITE; ENZYME PURIFICATION; ESCHERICHIA COLI; GENE MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; WILD TYPE; YERSINIA PESTIS;

AMINO ACID SUBSTITUTION; ARGININE; CATALYTIC DOMAIN; DNA TOPOISOMERASES, TYPE I; DNA, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; MUTATION, MISSENSE; TOPOISOMERASE I INHIBITORS; YERSINIA PESTIS;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; YERSINIA PESTIS;

EID: 79956333418     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.229450     Document Type: Article

References (40)

1. Wang, J. C. (2002) Nat. Rev. Mol. Cell Biol. 3, 430-440
2. Schoeffler, A. J., and Berger, J. M. (2008) Q. Rev. Biophys. 41, 41-101
3. Pommier, Y., Leo, E., Zhang, H., and Marchand, C. (2010) Chem. Biol. 17, 421-433
4. Nitiss, J. L. (2009) Nat. Rev. Cancer 9, 338-350
5. Bradbury, B. J., and Pucci, M. J. (2008) Curr. Opin. Pharmacol. 8, 574-581
6. Drlica, K., Malik, M., Kerns, R. J., and Zhao, X. (2008) Antimicrob. Agents Chemother. 52, 385-392
7. Deweese, J. E., and Osheroff, N. (2009) Nucleic Acids Res. 37, 738-748
8. Tse-Dinh, Y. C. (1998) Biochim. Biophys. Acta 1400, 19-27
9. Viard, T., and de la Tour, C. B. (2007) Biochimie 89, 456-467
10. Forterre, P., Gribaldo, S., Gadelle, D., and Serre, M. C. (2007) Biochimie 89, 427-446
11. Forterre, P., and Gadelle, D. (2009) Nucleic Acids Res. 37, 679-692
12. Tse, Y. C., Kirkegaard, K., and Wang, J. C. (1980) J. Biol. Chem. 255, 5560-5565
13. Corbett, K. D., and Berger, J. M. (2004) Annu. Rev. Biophys. Biomol. Struct. 33, 95-118
14. Phillips, I., Culebras, E., Moreno, F., and Baquero, F. (1987) J. Antimicrob. Chemother. 20, 631-638
15. Lima, C. D., Wang, J. C., and Mondragón, A. (1994) Nature 367, 138-146
16. Strahs, D., Zhu, C. X., Cheng, B., Chen, J., and Tse-Dinh, Y. C. (2006) Nucleic Acids Res. 34, 1785-1797
17. Zhu, C. X., Roche, C. J., Papanicolaou, N., DiPietrantonio, A., and Tse-Dinh, Y. C. (1998) J. Biol. Chem. 273, 8783-8789
18. Chen, S. J., and Wang, J. C. (1998) J. Biol. Chem. 273, 6050-6056
19. Schmidt, B. H., Burgin, A. B., Deweese, J. E., Osheroff, N., and Berger, J. M. (2010) Nature 465, 641-644
20. Zhu, C. X., and Tse-Dinh, Y. C. (2000) J. Biol. Chem. 275, 5318-5322
21. Aravind, L., Leipe, D. D., and Koonin, E. V. (1998) Nucleic Acids Res. 26, 4205-4213
22. Cheng, B., Shukla, S., Vasunilashorn, S., Mukhopadhyay, S., and Tse-Dinh, Y. C. (2005) J. Biol. Chem. 280, 38489-38495
23. Cheng, B., Annamalai, T., Sorokin, E., Abrenica, M., Aedo, S., and Tse-Dinh, Y. C. (2009) J. Mol. Biol. 385, 558-567
24. Zhu, C. X., and Tse-Dinh, Y. C. (1999) Methods Mol. Biol. 94, 145-151
25. Changela, A., DiGate, R. J., and Mondragón, A. (2001) Nature 411, 1077-1081
26. Doyle, S. A. (2005) Methods Mol. Biol. 310, 107-113
27. Corn, J. E., Pease, P. J., Hura, G. L., and Berger, J. M. (2005) Mol. Cell 20, 391-401
28. Sorokin, E. P., Cheng, B., Rathi, S., Aedo, S. J., Abrenica, M. V., and Tse-Dinh, Y. C. (2008) Nucleic Acids Res. 36, 4788-4796
29. Stern, J. C., and Schildbach, J. F. (2001) Biochemistry 40, 11586-11595
30. Heitman, J., and Model, P. (1991) Gene 103, 1-9
31. Caron, P. R. (1999) Methods Mol. Biol. 94, 279-316
32. Cheng, B., Sorokin, E. P., and Tse-Dinh, Y. C. (2008) Nucleic Acids Res. 36, 1017-1025
33. Narula, G., Becker, J., Cheng, B., Dani, N., Abrenica, M. V., and Tse-Dinh, Y. C. (2010) BMC Biochem. 11, 41
34. Wang, Y., Lynch, A. S., Chen, S. J., and Wang, J. C. (2002) J. Biol. Chem. 277, 1203-1209
35. Tse-Dinh, Y. C. (1986) J. Biol. Chem. 261, 10931-10935
36. Deweese, J. E., Burch, A. M., Burgin, A. B., and Osheroff, N. (2009) Biochemistry 48, 1862-1869
37. Das, U., Hariprasad, G., Ethayathulla, A. S., Manral, P., Das, T. K., Pasha, S., Mann, A., Ganguli, M., Verma, A. K., Bhat, R., Chandrayan, S. K., Ahmed, S., Sharma, S., Kaur, P., Singh, T. P., and Srinivasan, A. (2007) PLoS One 2, e1176
38. Depew, R. E., Liu, L. F., and Wang, J. C. (1978) J. Biol. Chem. 253, 511-518
39. Goto, T., Laipis, P., and Wang, J. C. (1984) J. Biol. Chem. 259, 10422-10429
40. Sissi, C., and Palumbo, M. (2009) Nucleic Acids Res. 37, 702-711