Using Active Site Mapping and Receptor-Based Pharmacophore Tools: Prelude to Docking and De Novo/Fragment-Based Ligand Design

Methods in Molecular Biology

Volumn 716, Issue , 2011, Pages 39-54

  Tripathi, Ashutosh ^a   Surface, J Andrew ^a   Kellogg, Glen E ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Cavity detection; Cavity mapping; Computer aided drug design; De novo drug design; Docking; HINT; Pharmacophore

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; LIGAND;

ANIMAL; ARTICLE; BINDING SITE; CATTLE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER AIDED DESIGN; DRUG DESIGN; METABOLISM; MOUSE; PROTEIN BINDING;

ANIMALS; BINDING SITES; CATTLE; COMPUTER-AIDED DESIGN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DRUG DESIGN; LIGANDS; MICE; MODELS, MOLECULAR; PROTEIN BINDING;

EID: 79956213667     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-61779-012-6_3     Document Type: Chapter

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