-
1
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson J.A., Itskovitz-Eldor J., Shapiro S.S., Waknitz M.A., Swiergiel J.J., Marshall V.S., Jones J.M. Embryonic stem cell lines derived from human blastocysts. Science 1998, 282:1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
2
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K., Tanabe K., Ohnuki M., Narita M., Ichisaka T., Tomoda K., Yamanaka S. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007, 131:861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
3
-
-
34249908901
-
In vitro reprogramming of fibroblasts into a pluripotent es-cell-like state
-
Wernig M., Meissner A., Foreman R., Brambrink T., Ku M., Hochedlinger K., Bernstein B.E., Jaenisch R. In vitro reprogramming of fibroblasts into a pluripotent es-cell-like state. Nature 2007, 448:318-324.
-
(2007)
Nature
, vol.448
, pp. 318-324
-
-
Wernig, M.1
Meissner, A.2
Foreman, R.3
Brambrink, T.4
Ku, M.5
Hochedlinger, K.6
Bernstein, B.E.7
Jaenisch, R.8
-
4
-
-
77958569435
-
Induced pluripotency: history, mechanisms, and applications
-
Stadtfeld M., Hochedlinger K. Induced pluripotency: history, mechanisms, and applications. Genes Dev 2010, 24:2239-2263.
-
(2010)
Genes Dev
, vol.24
, pp. 2239-2263
-
-
Stadtfeld, M.1
Hochedlinger, K.2
-
5
-
-
78149487692
-
Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues
-
Hanna J.H., Saha K., Jaenisch R. Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell 2010, 143:508-525.
-
(2010)
Cell
, vol.143
, pp. 508-525
-
-
Hanna, J.H.1
Saha, K.2
Jaenisch, R.3
-
6
-
-
70350536767
-
A small-molecule inhibitor of tgf-beta signaling replaces sox2 in reprogramming by inducing nanog
-
Ichida J.K., Blanchard J., Lam K., Son E.Y., Chung J.E., Egli D., Loh K.M., Carter A.C., Di Giorgio F.P., Koszka K., et al. A small-molecule inhibitor of tgf-beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell 2009, 5:491-503.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 491-503
-
-
Ichida, J.K.1
Blanchard, J.2
Lam, K.3
Son, E.Y.4
Chung, J.E.5
Egli, D.6
Loh, K.M.7
Carter, A.C.8
Di Giorgio, F.P.9
Koszka, K.10
-
7
-
-
67049158201
-
Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of klf4
-
Lyssiotis C.A., Foreman R.K., Staerk J., Garcia M., Mathur D., Markoulaki S., Hanna J., Lairson L.L., Charette B.D., Bouchez L.C., et al. Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of klf4. Proc Natl Acad Sci U S A 2009, 106:8912-8917.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 8912-8917
-
-
Lyssiotis, C.A.1
Foreman, R.K.2
Staerk, J.3
Garcia, M.4
Mathur, D.5
Markoulaki, S.6
Hanna, J.7
Lairson, L.L.8
Charette, B.D.9
Bouchez, L.C.10
-
8
-
-
49449096588
-
A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types
-
Wernig M., Lengner C.J., Hanna J., Lodato M.A., Steine E., Foreman R., Staerk J., Markoulaki S., Jaenisch R. A drug-inducible transgenic system for direct reprogramming of multiple somatic cell types. Nat Biotechnol 2008, 26:916-924.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 916-924
-
-
Wernig, M.1
Lengner, C.J.2
Hanna, J.3
Lodato, M.A.4
Steine, E.5
Foreman, R.6
Staerk, J.7
Markoulaki, S.8
Jaenisch, R.9
-
9
-
-
48349095740
-
Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors
-
Kim J.B., Zaehres H., Wu G., Gentile L., Ko K., Sebastiano V., Arauzo-Bravo M.J., Ruau D., Han D.W., Zenke M., Scholer H.R. Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors. Nature 2008, 454:646-650.
-
(2008)
Nature
, vol.454
, pp. 646-650
-
-
Kim, J.B.1
Zaehres, H.2
Wu, G.3
Gentile, L.4
Ko, K.5
Sebastiano, V.6
Arauzo-Bravo, M.J.7
Ruau, D.8
Han, D.W.9
Zenke, M.10
Scholer, H.R.11
-
10
-
-
70350508292
-
Cell-free production of transducible transcription factors for nuclear reprogramming
-
Yang W.C., Patel K.G., Lee J., Ghebremariam Y.T., Wong H.E., Cooke J.P., Swartz J.R. Cell-free production of transducible transcription factors for nuclear reprogramming. Biotechnol Bioeng 2009, 104:1047-1058.
-
(2009)
Biotechnol Bioeng
, vol.104
, pp. 1047-1058
-
-
Yang, W.C.1
Patel, K.G.2
Lee, J.3
Ghebremariam, Y.T.4
Wong, H.E.5
Cooke, J.P.6
Swartz, J.R.7
-
11
-
-
71449109765
-
Direct cell reprogramming is a stochastic process amenable to acceleration
-
Hanna J., Saha K., Pando B., van Zon J., Lengner C.J., Creyghton M.P., van Oudenaarden A., Jaenisch R. Direct cell reprogramming is a stochastic process amenable to acceleration. Nature 2009, 462:595-601.
-
(2009)
Nature
, vol.462
, pp. 595-601
-
-
Hanna, J.1
Saha, K.2
Pando, B.3
van Zon, J.4
Lengner, C.J.5
Creyghton, M.P.6
van Oudenaarden, A.7
Jaenisch, R.8
-
12
-
-
62949220231
-
Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells
-
Feng B., Ng J.H., Heng J.C., Ng H.H. Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. Cell Stem Cell 2009, 4:301-312.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 301-312
-
-
Feng, B.1
Ng, J.H.2
Heng, J.C.3
Ng, H.H.4
-
13
-
-
59649105969
-
Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor esrrb
-
Feng B., Jiang J., Kraus P., Ng J.H., Heng J.C., Chan Y.S., Yaw L.P., Zhang W., Loh Y.H., Han J., et al. Reprogramming of fibroblasts into induced pluripotent stem cells with orphan nuclear receptor esrrb. Nat Cell Biol 2009, 11:197-203.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 197-203
-
-
Feng, B.1
Jiang, J.2
Kraus, P.3
Ng, J.H.4
Heng, J.C.5
Chan, Y.S.6
Yaw, L.P.7
Zhang, W.8
Loh, Y.H.9
Han, J.10
-
14
-
-
54949105021
-
Promotion of reprogramming to ground state pluripotency by signal inhibition
-
Silva J., Barrandon O., Nichols J., Kawaguchi J., Theunissen T.W., Smith A. Promotion of reprogramming to ground state pluripotency by signal inhibition. PLoS Biol 2008, 6:e253.
-
(2008)
PLoS Biol
, vol.6
-
-
Silva, J.1
Barrandon, O.2
Nichols, J.3
Kawaguchi, J.4
Theunissen, T.W.5
Smith, A.6
-
15
-
-
77958536106
-
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mrna
-
Warren L., Manos P.D., Ahfeldt T., Loh Y.H., Li H., Lau F., Ebina W., Mandal P.K., Smith Z.D., Meissner A., et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mrna. Cell Stem Cell 2010, 7:618-630.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 618-630
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
Loh, Y.H.4
Li, H.5
Lau, F.6
Ebina, W.7
Mandal, P.K.8
Smith, Z.D.9
Meissner, A.10
-
16
-
-
65449121435
-
Isolation of human ips cells using eos lentiviral vectors to select for pluripotency
-
Hotta A., Cheung A.Y., Farra N., Vijayaragavan K., Seguin C.A., Draper J.S., Pasceri P., Maksakova I.A., Mager D.L., Rossant J., et al. Isolation of human ips cells using eos lentiviral vectors to select for pluripotency. Nat Methods 2009, 6:370-376.
-
(2009)
Nat Methods
, vol.6
, pp. 370-376
-
-
Hotta, A.1
Cheung, A.Y.2
Farra, N.3
Vijayaragavan, K.4
Seguin, C.A.5
Draper, J.S.6
Pasceri, P.7
Maksakova, I.A.8
Mager, D.L.9
Rossant, J.10
-
17
-
-
78149488365
-
A model for neural development and treatment of rett syndrome using human induced pluripotent stem cells
-
Marchetto M.C., Carromeu C., Acab A., Yu D., Yeo G.W., Mu Y., Chen G., Gage F.H., Muotri A.R. A model for neural development and treatment of rett syndrome using human induced pluripotent stem cells. Cell 2010, 143:527-539.
-
(2010)
Cell
, vol.143
, pp. 527-539
-
-
Marchetto, M.C.1
Carromeu, C.2
Acab, A.3
Yu, D.4
Yeo, G.W.5
Mu, Y.6
Chen, G.7
Gage, F.H.8
Muotri, A.R.9
-
18
-
-
77956214743
-
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells
-
Urbach A., Bar-Nur O., Daley G.Q., Benvenisty N. Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell 2010, 6:407-411.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 407-411
-
-
Urbach, A.1
Bar-Nur, O.2
Daley, G.Q.3
Benvenisty, N.4
-
19
-
-
78049303170
-
Induced pluripotent stem cell models of the genomic imprinting disorders angelman and prader-willi syndromes
-
Chamberlain S.J., Chen P.F., Ng K.Y., Bourgois-Rocha F., Lemtiri-Chlieh F., Levine E.S., Lalande M. Induced pluripotent stem cell models of the genomic imprinting disorders angelman and prader-willi syndromes. Proc Natl Acad Sci U S A 2010, 107:17668-17673.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 17668-17673
-
-
Chamberlain, S.J.1
Chen, P.F.2
Ng, K.Y.3
Bourgois-Rocha, F.4
Lemtiri-Chlieh, F.5
Levine, E.S.6
Lalande, M.7
-
20
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
Ebert A.D., Yu J., Rose F.F., Mattis V.B., Lorson C.L., Thomson J.A., Svendsen C.N. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2009, 457:277-280.
-
(2009)
Nature
, vol.457
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose, F.F.3
Mattis, V.B.4
Lorson, C.L.5
Thomson, J.A.6
Svendsen, C.N.7
-
21
-
-
77953879152
-
Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases
-
Marchetto M.C., Winner B., Gage F.H. Pluripotent stem cells in neurodegenerative and neurodevelopmental diseases. Hum Mol Genet 2010, 19:R71-76.
-
(2010)
Hum Mol Genet
, vol.19
-
-
Marchetto, M.C.1
Winner, B.2
Gage, F.H.3
-
22
-
-
70349301819
-
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific ipscs
-
Lee G., Papapetrou E.P., Kim H., Chambers S.M., Tomishima M.J., Fasano C.A., Ganat Y.M., Menon J., Shimizu F., Viale A., et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific ipscs. Nature 2009, 461:402-406.
-
(2009)
Nature
, vol.461
, pp. 402-406
-
-
Lee, G.1
Papapetrou, E.P.2
Kim, H.3
Chambers, S.M.4
Tomishima, M.J.5
Fasano, C.A.6
Ganat, Y.M.7
Menon, J.8
Shimizu, F.9
Viale, A.10
-
23
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
Park I.H., Arora N., Huo H., Maherali N., Ahfeldt T., Shimamura A., Lensch M.W., Cowan C., Hochedlinger K., Daley G.Q. Disease-specific induced pluripotent stem cells. Cell 2008, 134:877-886.
-
(2008)
Cell
, vol.134
, pp. 877-886
-
-
Park, I.H.1
Arora, N.2
Huo, H.3
Maherali, N.4
Ahfeldt, T.5
Shimamura, A.6
Lensch, M.W.7
Cowan, C.8
Hochedlinger, K.9
Daley, G.Q.10
-
24
-
-
0033646967
-
Rett syndrome: methyl-cpg-binding protein 2 mutations and phenotype-genotype correlations
-
Amir R.E., Zoghbi H.Y. Rett syndrome: methyl-cpg-binding protein 2 mutations and phenotype-genotype correlations. Am J Med Genet 2000, 97:147-152.
-
(2000)
Am J Med Genet
, vol.97
, pp. 147-152
-
-
Amir, R.E.1
Zoghbi, H.Y.2
-
25
-
-
0032830639
-
Rett syndrome is caused by mutations in x-linked mecp2, encoding methyl-cpg-binding protein 2
-
Amir R.E., Van den Veyver I.B., Wan M., Tran C.Q., Francke U., Zoghbi H.Y. Rett syndrome is caused by mutations in x-linked mecp2, encoding methyl-cpg-binding protein 2. Nat Genet 1999, 23:185-188.
-
(1999)
Nat Genet
, vol.23
, pp. 185-188
-
-
Amir, R.E.1
Van den Veyver, I.B.2
Wan, M.3
Tran, C.Q.4
Francke, U.5
Zoghbi, H.Y.6
-
26
-
-
78649632841
-
Evolving role of mecp2 in rett syndrome and autism
-
Lasalle J.M., Yasui D.H. Evolving role of mecp2 in rett syndrome and autism. Epigenomics 2009, 1:119-130.
-
(2009)
Epigenomics
, vol.1
, pp. 119-130
-
-
Lasalle, J.M.1
Yasui, D.H.2
-
27
-
-
67650139492
-
Mecp2 promoter methylation and X chromosome inactivation in autism
-
Nagarajan R.P., Patzel K.A., Martin M., Yasui D.H., Swanberg S.E., Hertz-Picciotto I., Hansen R.L., Van de Water J., Pessah I.N., Jiang R., et al. Mecp2 promoter methylation and X chromosome inactivation in autism. Autism Res 2008, 1:169-178.
-
(2008)
Autism Res
, vol.1
, pp. 169-178
-
-
Nagarajan, R.P.1
Patzel, K.A.2
Martin, M.3
Yasui, D.H.4
Swanberg, S.E.5
Hertz-Picciotto, I.6
Hansen, R.L.7
Van de Water, J.8
Pessah, I.N.9
Jiang, R.10
-
28
-
-
64349106730
-
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming
-
Deng J., Shoemaker R., Xie B., Gore A., LeProust E.M., Antosiewicz-Bourget J., Egli D., Maherali N., Park I.H., Yu J., et al. Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol 2009, 27:353-360.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 353-360
-
-
Deng, J.1
Shoemaker, R.2
Xie, B.3
Gore, A.4
LeProust, E.M.5
Antosiewicz-Bourget, J.6
Egli, D.7
Maherali, N.8
Park, I.H.9
Yu, J.10
-
29
-
-
69249208658
-
Pluripotent stem cells and disease modeling
-
Colman A., Dreesen O. Pluripotent stem cells and disease modeling. Cell Stem Cell 2009, 5:244-247.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 244-247
-
-
Colman, A.1
Dreesen, O.2
-
30
-
-
67650084389
-
Induced pluripotent stem cells and the stability of the differentiated state
-
Colman A., Dreesen O. Induced pluripotent stem cells and the stability of the differentiated state. EMBO Rep 2009, 10:714-721.
-
(2009)
EMBO Rep
, vol.10
, pp. 714-721
-
-
Colman, A.1
Dreesen, O.2
-
31
-
-
78149431869
-
Dysfunction in gaba signalling mediates autism-like stereotypies and rett syndrome phenotypes
-
Chao H.T., Chen H., Samaco R.C., Xue M., Chahrour M., Yoo J., Neul J.L., Gong S., Lu H.C., Heintz N., et al. Dysfunction in gaba signalling mediates autism-like stereotypies and rett syndrome phenotypes. Nature 2010, 468:263-269.
-
(2010)
Nature
, vol.468
, pp. 263-269
-
-
Chao, H.T.1
Chen, H.2
Samaco, R.C.3
Xue, M.4
Chahrour, M.5
Yoo, J.6
Neul, J.L.7
Gong, S.8
Lu, H.C.9
Heintz, N.10
-
32
-
-
0037371609
-
Tissue-specific reduction in splicing efficiency of ikbkap due to the major mutation associated with familial dysautonomia
-
Cuajungco M.P., Leyne M., Mull J., Gill S.P., Lu W., Zagzag D., Axelrod F.B., Maayan C., Gusella J.F., Slaugenhaupt S.A. Tissue-specific reduction in splicing efficiency of ikbkap due to the major mutation associated with familial dysautonomia. Am J Hum Genet 2003, 72:749-758.
-
(2003)
Am J Hum Genet
, vol.72
, pp. 749-758
-
-
Cuajungco, M.P.1
Leyne, M.2
Mull, J.3
Gill, S.P.4
Lu, W.5
Zagzag, D.6
Axelrod, F.B.7
Maayan, C.8
Gusella, J.F.9
Slaugenhaupt, S.A.10
-
33
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
Soldner F., Hockemeyer D., Beard C., Gao Q., Bell G.W., Cook E.G., Hargus G., Blak A., Cooper O., Mitalipova M., et al. Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 2009, 136:964-977.
-
(2009)
Cell
, vol.136
, pp. 964-977
-
-
Soldner, F.1
Hockemeyer, D.2
Beard, C.3
Gao, Q.4
Bell, G.W.5
Cook, E.G.6
Hargus, G.7
Blak, A.8
Cooper, O.9
Mitalipova, M.10
-
34
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with als can be differentiated into motor neurons
-
Dimos J.T., Rodolfa K.T., Niakan K.K., Weisenthal L.M., Mitsumoto H., Chung W., Croft G.F., Saphier G., Leibel R., Goland R., et al. Induced pluripotent stem cells generated from patients with als can be differentiated into motor neurons. Science 2008, 321:1218-1221.
-
(2008)
Science
, vol.321
, pp. 1218-1221
-
-
Dimos, J.T.1
Rodolfa, K.T.2
Niakan, K.K.3
Weisenthal, L.M.4
Mitsumoto, H.5
Chung, W.6
Croft, G.F.7
Saphier, G.8
Leibel, R.9
Goland, R.10
-
35
-
-
0026337175
-
Oxidative stress as a cause of parkinson's disease
-
Jenner P. Oxidative stress as a cause of parkinson's disease. Acta Neurol Scand Suppl 1991, 136:6-15.
-
(1991)
Acta Neurol Scand Suppl
, vol.136
, pp. 6-15
-
-
Jenner, P.1
-
36
-
-
0033825627
-
Oxidative stress and genetics in the pathogenesis of parkinson's disease
-
Zhang Y., Dawson V.L., Dawson T.M. Oxidative stress and genetics in the pathogenesis of parkinson's disease. Neurobiol Dis 2000, 7:240-250.
-
(2000)
Neurobiol Dis
, vol.7
, pp. 240-250
-
-
Zhang, Y.1
Dawson, V.L.2
Dawson, T.M.3
-
37
-
-
77957670482
-
Differentiated parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in parkinsonian rats
-
Hargus G., Cooper O., Deleidi M., Levy A., Lee K., Marlow E., Yow A., Soldner F., Hockemeyer D., Hallett P.J., et al. Differentiated parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in parkinsonian rats. Proc Natl Acad Sci U S A 2010, 107:15921-15926.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15921-15926
-
-
Hargus, G.1
Cooper, O.2
Deleidi, M.3
Levy, A.4
Lee, K.5
Marlow, E.6
Yow, A.7
Soldner, F.8
Hockemeyer, D.9
Hallett, P.J.10
-
38
-
-
77749279749
-
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
-
Hu B.Y., Weick J.P., Yu J., Ma L.X., Zhang X.Q., Thomson J.A., Zhang S.C. Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc Natl Acad Sci U S A 2010, 107:4335-4340.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 4335-4340
-
-
Hu, B.Y.1
Weick, J.P.2
Yu, J.3
Ma, L.X.4
Zhang, X.Q.5
Thomson, J.A.6
Zhang, S.C.7
-
39
-
-
14544296563
-
Directed differentiation of telencephalic precursors from embryonic stem cells
-
Watanabe K., Kamiya D., Nishiyama A., Katayama T., Nozaki S., Kawasaki H., Watanabe Y., Mizuseki K., Sasai Y. Directed differentiation of telencephalic precursors from embryonic stem cells. Nat Neurosci 2005, 8:288-296.
-
(2005)
Nat Neurosci
, vol.8
, pp. 288-296
-
-
Watanabe, K.1
Kamiya, D.2
Nishiyama, A.3
Katayama, T.4
Nozaki, S.5
Kawasaki, H.6
Watanabe, Y.7
Mizuseki, K.8
Sasai, Y.9
-
40
-
-
70349106392
-
Generation of cortical neurons from mouse embryonic stem cells
-
Gaspard N., Bouschet T., Herpoel A., Naeije G., van den Ameele J., Vanderhaeghen P. Generation of cortical neurons from mouse embryonic stem cells. Nat Protoc 2009, 4:1454-1463.
-
(2009)
Nat Protoc
, vol.4
, pp. 1454-1463
-
-
Gaspard, N.1
Bouschet, T.2
Herpoel, A.3
Naeije, G.4
van den Ameele, J.5
Vanderhaeghen, P.6
-
41
-
-
54949102049
-
Self-organized formation of polarized cortical tissues from escs and its active manipulation by extrinsic signals
-
Eiraku M., Watanabe K., Matsuo-Takasaki M., Kawada M., Yonemura S., Matsumura M., Wataya T., Nishiyama A., Muguruma K., Sasai Y. Self-organized formation of polarized cortical tissues from escs and its active manipulation by extrinsic signals. Cell Stem Cell 2008, 3:519-532.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 519-532
-
-
Eiraku, M.1
Watanabe, K.2
Matsuo-Takasaki, M.3
Kawada, M.4
Yonemura, S.5
Matsumura, M.6
Wataya, T.7
Nishiyama, A.8
Muguruma, K.9
Sasai, Y.10
-
42
-
-
52149102948
-
An intrinsic mechanism of corticogenesis from embryonic stem cells
-
Gaspard N., Bouschet T., Hourez R., Dimidschstein J., Naeije G., van den Ameele J., Espuny-Camacho I., Herpoel A., Passante L., Schiffmann S.N., et al. An intrinsic mechanism of corticogenesis from embryonic stem cells. Nature 2008, 455:351-357.
-
(2008)
Nature
, vol.455
, pp. 351-357
-
-
Gaspard, N.1
Bouschet, T.2
Hourez, R.3
Dimidschstein, J.4
Naeije, G.5
van den Ameele, J.6
Espuny-Camacho, I.7
Herpoel, A.8
Passante, L.9
Schiffmann, S.N.10
-
43
-
-
44449116119
-
Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells
-
Kondo T., Sheets P.L., Zopf D.A., Aloor H.L., Cummins T.R., Chan R.J., Hashino E. Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells. Proc Natl Acad Sci U S A 2008, 105:5780-5785.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 5780-5785
-
-
Kondo, T.1
Sheets, P.L.2
Zopf, D.A.3
Aloor, H.L.4
Cummins, T.R.5
Chan, R.J.6
Hashino, E.7
-
44
-
-
24944484633
-
Niche-independent symmetrical self-renewal of a mammalian tissue stem cell
-
Conti L., Pollard S.M., Gorba T., Reitano E., Toselli M., Biella G., Sun Y., Sanzone S., Ying Q.L., Cattaneo E., Smith A. Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biol 2005, 3:e283.
-
(2005)
PLoS Biol
, vol.3
-
-
Conti, L.1
Pollard, S.M.2
Gorba, T.3
Reitano, E.4
Toselli, M.5
Biella, G.6
Sun, Y.7
Sanzone, S.8
Ying, Q.L.9
Cattaneo, E.10
Smith, A.11
-
45
-
-
70450159769
-
Coordination of sonic hedgehog and wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells
-
Li X.J., Zhang X., Johnson M.A., Wang Z.B., Lavaute T., Zhang S.C. Coordination of sonic hedgehog and wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells. Development 2009, 136:4055-4063.
-
(2009)
Development
, vol.136
, pp. 4055-4063
-
-
Li, X.J.1
Zhang, X.2
Johnson, M.A.3
Wang, Z.B.4
Lavaute, T.5
Zhang, S.C.6
-
46
-
-
77950688386
-
Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells
-
Maroof A.M., Brown K., Shi S.H., Studer L., Anderson S.A. Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells. J Neurosci 2010, 30:4667-4675.
-
(2010)
J Neurosci
, vol.30
, pp. 4667-4675
-
-
Maroof, A.M.1
Brown, K.2
Shi, S.H.3
Studer, L.4
Anderson, S.A.5
-
47
-
-
64349101680
-
An optimized experimental strategy for efficient conversion of embryonic stem (es)-derived mouse neural stem (ns) cells into a nearly homogeneous mature neuronal population
-
Spiliotopoulos D., Goffredo D., Conti L., Di Febo F., Biella G., Toselli M., Cattaneo E. An optimized experimental strategy for efficient conversion of embryonic stem (es)-derived mouse neural stem (ns) cells into a nearly homogeneous mature neuronal population. Neurobiol Dis 2009, 34:320-331.
-
(2009)
Neurobiol Dis
, vol.34
, pp. 320-331
-
-
Spiliotopoulos, D.1
Goffredo, D.2
Conti, L.3
Di Febo, F.4
Biella, G.5
Toselli, M.6
Cattaneo, E.7
-
48
-
-
67349129378
-
Derivation of homogeneous gabaergic neurons from mouse embryonic stem cells
-
Chatzi C., Scott R.H., Pu J., Lang B., Nakamoto C., McCaig C.D., Shen S. Derivation of homogeneous gabaergic neurons from mouse embryonic stem cells. Exp Neurol 2009, 217:407-416.
-
(2009)
Exp Neurol
, vol.217
, pp. 407-416
-
-
Chatzi, C.1
Scott, R.H.2
Pu, J.3
Lang, B.4
Nakamoto, C.5
McCaig, C.D.6
Shen, S.7
-
49
-
-
50149096140
-
Minimization of exogenous signals in es cell culture induces rostral hypothalamic differentiation
-
Wataya T., Ando S., Muguruma K., Ikeda H., Watanabe K., Eiraku M., Kawada M., Takahashi J., Hashimoto N., Sasai Y. Minimization of exogenous signals in es cell culture induces rostral hypothalamic differentiation. Proc Natl Acad Sci U S A 2008, 105:11796-11801.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 11796-11801
-
-
Wataya, T.1
Ando, S.2
Muguruma, K.3
Ikeda, H.4
Watanabe, K.5
Eiraku, M.6
Kawada, M.7
Takahashi, J.8
Hashimoto, N.9
Sasai, Y.10
-
50
-
-
0033638174
-
Induction of midbrain dopaminergic neurons from es cells by stromal cell-derived inducing activity
-
Kawasaki H., Mizuseki K., Nishikawa S., Kaneko S., Kuwana Y., Nakanishi S., Nishikawa S.I., Sasai Y. Induction of midbrain dopaminergic neurons from es cells by stromal cell-derived inducing activity. Neuron 2000, 28:31-40.
-
(2000)
Neuron
, vol.28
, pp. 31-40
-
-
Kawasaki, H.1
Mizuseki, K.2
Nishikawa, S.3
Kaneko, S.4
Kuwana, Y.5
Nakanishi, S.6
Nishikawa, S.I.7
Sasai, Y.8
-
51
-
-
20044383922
-
In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons
-
Park C.H., Minn Y.K., Lee J.Y., Choi D.H., Chang M.Y., Shim J.W., Ko J.Y., Koh H.C., Kang M.J., Kang J.S., et al. In vitro and in vivo analyses of human embryonic stem cell-derived dopamine neurons. J Neurochem 2005, 92:1265-1276.
-
(2005)
J Neurochem
, vol.92
, pp. 1265-1276
-
-
Park, C.H.1
Minn, Y.K.2
Lee, J.Y.3
Choi, D.H.4
Chang, M.Y.5
Shim, J.W.6
Ko, J.Y.7
Koh, H.C.8
Kang, M.J.9
Kang, J.S.10
-
52
-
-
33845277826
-
A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo
-
Iacovitti L., Donaldson A.E., Marshall C.E., Suon S., Yang M. A protocol for the differentiation of human embryonic stem cells into dopaminergic neurons using only chemically defined human additives: Studies in vitro and in vivo. Brain Res 2007, 1127:19-25.
-
(2007)
Brain Res
, vol.1127
, pp. 19-25
-
-
Iacovitti, L.1
Donaldson, A.E.2
Marshall, C.E.3
Suon, S.4
Yang, M.5
-
53
-
-
77956613688
-
Differentiation of human es and parkinson's disease ips cells into ventral midbrain dopaminergic neurons requires a high activity form of shh, fgf8a and specific regionalization by retinoic acid
-
Cooper O., Hargus G., Deleidi M., Blak A., Osborn T., Marlow E., Lee K., Levy A., Perez-Torres E., Yow A., Isacson O. Differentiation of human es and parkinson's disease ips cells into ventral midbrain dopaminergic neurons requires a high activity form of shh, fgf8a and specific regionalization by retinoic acid. Mol Cell Neurosci 2010, 45:258-266.
-
(2010)
Mol Cell Neurosci
, vol.45
, pp. 258-266
-
-
Cooper, O.1
Hargus, G.2
Deleidi, M.3
Blak, A.4
Osborn, T.5
Marlow, E.6
Lee, K.7
Levy, A.8
Perez-Torres, E.9
Yow, A.10
Isacson, O.11
-
54
-
-
42149107420
-
Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells
-
Cho M.S., Lee Y.E., Kim J.Y., Chung S., Cho Y.H., Kim D.S., Kang S.M., Lee H., Kim M.H., Kim J.H., et al. Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci U S A 2008, 105:3392-3397.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 3392-3397
-
-
Cho, M.S.1
Lee, Y.E.2
Kim, J.Y.3
Chung, S.4
Cho, Y.H.5
Kim, D.S.6
Kang, S.M.7
Lee, H.8
Kim, M.H.9
Kim, J.H.10
-
55
-
-
35448952847
-
Human embryonic stem cell-derived neural precursors as a continuous, stable, and on-demand source for human dopamine neurons
-
Ko J.Y., Park C.H., Koh H.C., Cho Y.H., Kyhm J.H., Kim Y.S., Lee I., Lee Y.S., Lee S.H. Human embryonic stem cell-derived neural precursors as a continuous, stable, and on-demand source for human dopamine neurons. J Neurochem 2007, 103:1417-1429.
-
(2007)
J Neurochem
, vol.103
, pp. 1417-1429
-
-
Ko, J.Y.1
Park, C.H.2
Koh, H.C.3
Cho, Y.H.4
Kyhm, J.H.5
Kim, Y.S.6
Lee, I.7
Lee, Y.S.8
Lee, S.H.9
-
56
-
-
33847271710
-
Differentiation of es cells into cerebellar neurons
-
Salero E., Hatten M.E. Differentiation of es cells into cerebellar neurons. Proc Natl Acad Sci U S A 2007, 104:2997-3002.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 2997-3002
-
-
Salero, E.1
Hatten, M.E.2
-
57
-
-
31544468914
-
Generation of cerebellar neuron precursors from embryonic stem cells
-
Su H.L., Muguruma K., Matsuo-Takasaki M., Kengaku M., Watanabe K., Sasai Y. Generation of cerebellar neuron precursors from embryonic stem cells. Dev Biol 2006, 290:287-296.
-
(2006)
Dev Biol
, vol.290
, pp. 287-296
-
-
Su, H.L.1
Muguruma, K.2
Matsuo-Takasaki, M.3
Kengaku, M.4
Watanabe, K.5
Sasai, Y.6
-
58
-
-
78049384146
-
Efficient differentiation of human embryonic stem cells into functional cerebellar-like cells
-
Erceg S., Ronaghi M., Zipancic I., Lainez S., Rosello M.G., Xiong C., Moreno-Manzano V., Rodriguez-Jimenez F.J., Planells R., Alvarez-Dolado M., et al. Efficient differentiation of human embryonic stem cells into functional cerebellar-like cells. Stem Cells Dev 2010, 19:1745-1756.
-
(2010)
Stem Cells Dev
, vol.19
, pp. 1745-1756
-
-
Erceg, S.1
Ronaghi, M.2
Zipancic, I.3
Lainez, S.4
Rosello, M.G.5
Xiong, C.6
Moreno-Manzano, V.7
Rodriguez-Jimenez, F.J.8
Planells, R.9
Alvarez-Dolado, M.10
-
59
-
-
34547858511
-
Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons
-
Lee H., Shamy G.A., Elkabetz Y., Schofield C.M., Harrsion N.L., Panagiotakos G., Socci N.D., Tabar V., Studer L. Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons. Stem Cells 2007, 25:1931-1939.
-
(2007)
Stem Cells
, vol.25
, pp. 1931-1939
-
-
Lee, H.1
Shamy, G.A.2
Elkabetz, Y.3
Schofield, C.M.4
Harrsion, N.L.5
Panagiotakos, G.6
Socci, N.D.7
Tabar, V.8
Studer, L.9
-
60
-
-
47749108736
-
Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions
-
Erceg S., Lainez S., Ronaghi M., Stojkovic P., Perez-Arago M.A., Moreno-Manzano V., Moreno-Palanques R., Planells-Cases R., Stojkovic M. Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions. PLoS One 2008, 3:e2122.
-
(2008)
PLoS One
, vol.3
-
-
Erceg, S.1
Lainez, S.2
Ronaghi, M.3
Stojkovic, P.4
Perez-Arago, M.A.5
Moreno-Manzano, V.6
Moreno-Palanques, R.7
Planells-Cases, R.8
Stojkovic, M.9
-
61
-
-
0035690493
-
Enrichment of neurons and neural precursors from human embryonic stem cells
-
Carpenter M.K., Inokuma M.S., Denham J., Mujtaba T., Chiu C.P., Rao M.S. Enrichment of neurons and neural precursors from human embryonic stem cells. Exp Neurol 2001, 172:383-397.
-
(2001)
Exp Neurol
, vol.172
, pp. 383-397
-
-
Carpenter, M.K.1
Inokuma, M.S.2
Denham, J.3
Mujtaba, T.4
Chiu, C.P.5
Rao, M.S.6
-
62
-
-
69249202573
-
Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells
-
Wada T., Honda M., Minami I., Tooi N., Amagai Y., Nakatsuji N., Aiba K. Highly efficient differentiation and enrichment of spinal motor neurons derived from human and monkey embryonic stem cells. PLoS One 2009, 4:e6722.
-
(2009)
PLoS One
, vol.4
-
-
Wada, T.1
Honda, M.2
Minami, I.3
Tooi, N.4
Amagai, Y.5
Nakatsuji, N.6
Aiba, K.7
-
63
-
-
80055101665
-
Differentiation of embryonic stem cells into oligodendrocyte precursors
-
Jiang P., Selvaraj V., Deng W. Differentiation of embryonic stem cells into oligodendrocyte precursors. J Vis Exp 2010, 39.
-
(2010)
J Vis Exp
, vol.39
-
-
Jiang, P.1
Selvaraj, V.2
Deng, W.3
-
64
-
-
33747406250
-
Generation and characterization of oligodendrocytes from lineage-selectable embryonic stem cells in vitro
-
Billon N., Jolicoeur C., Raff M. Generation and characterization of oligodendrocytes from lineage-selectable embryonic stem cells in vitro. Methods Mol Biol 2006, 330:15-32.
-
(2006)
Methods Mol Biol
, vol.330
, pp. 15-32
-
-
Billon, N.1
Jolicoeur, C.2
Raff, M.3
-
65
-
-
0037106657
-
Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse es cells
-
Billon N., Jolicoeur C., Ying Q.L., Smith A., Raff M. Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse es cells. J Cell Sci 2002, 115:3657-3665.
-
(2002)
J Cell Sci
, vol.115
, pp. 3657-3665
-
-
Billon, N.1
Jolicoeur, C.2
Ying, Q.L.3
Smith, A.4
Raff, M.5
-
66
-
-
77950816148
-
Efficient differentiation of human embryonic stem cells into oligodendrocyte progenitors for application in a rat contusion model of spinal cord injury
-
Kerr C.L., Letzen B.S., Hill C.M., Agrawal G., Thakor N.V., Sterneckert J.L., Gearhart J.D., All A.H. Efficient differentiation of human embryonic stem cells into oligodendrocyte progenitors for application in a rat contusion model of spinal cord injury. Int J Neurosci 2010, 120:305-313.
-
(2010)
Int J Neurosci
, vol.120
, pp. 305-313
-
-
Kerr, C.L.1
Letzen, B.S.2
Hill, C.M.3
Agrawal, G.4
Thakor, N.V.5
Sterneckert, J.L.6
Gearhart, J.D.7
All, A.H.8
-
67
-
-
7244243971
-
Mecp2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions
-
Kishi N., Macklis J.D. Mecp2 is progressively expressed in post-migratory neurons and is involved in neuronal maturation rather than cell fate decisions. Mol Cell Neurosci 2004, 27:306-321.
-
(2004)
Mol Cell Neurosci
, vol.27
, pp. 306-321
-
-
Kishi, N.1
Macklis, J.D.2
-
68
-
-
0036917867
-
Rett syndrome and mecp2: linking epigenetics and neuronal function
-
Shahbazian M.D., Zoghbi H.Y. Rett syndrome and mecp2: linking epigenetics and neuronal function. Am J Hum Genet 2002, 71:1259-1272.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 1259-1272
-
-
Shahbazian, M.D.1
Zoghbi, H.Y.2
-
69
-
-
0028852641
-
Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) in Prader-Willi syndrome: a study of five cases
-
Swaab D.F., Purba J.S., Hofman M.A. Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) in Prader-Willi syndrome: a study of five cases. J Clin Endocrinol Metab 1995, 80:573-579.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 573-579
-
-
Swaab, D.F.1
Purba, J.S.2
Hofman, M.A.3
-
70
-
-
0030879482
-
Imprinted expression of the murine angelman syndrome gene, ube3a, in hippocampal and purkinje neurons
-
Albrecht U., Sutcliffe J.S., Cattanach B.M., Beechey C.V., Armstrong D., Eichele G., Beaudet A.L. Imprinted expression of the murine angelman syndrome gene, ube3a, in hippocampal and purkinje neurons. Nat Genet 1997, 17:75-78.
-
(1997)
Nat Genet
, vol.17
, pp. 75-78
-
-
Albrecht, U.1
Sutcliffe, J.S.2
Cattanach, B.M.3
Beechey, C.V.4
Armstrong, D.5
Eichele, G.6
Beaudet, A.L.7
-
71
-
-
37549057995
-
The angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology
-
Dindot S.V., Antalffy B.A., Bhattacharjee M.B., Beaudet A.L. The angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology. Hum Mol Genet 2008, 17:111-118.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 111-118
-
-
Dindot, S.V.1
Antalffy, B.A.2
Bhattacharjee, M.B.3
Beaudet, A.L.4
-
72
-
-
61849144426
-
Bmi-1 cooperates with foxg1 to maintain neural stem cell self-renewal in the forebrain
-
Fasano C.A., Phoenix T.N., Kokovay E., Lowry N., Elkabetz Y., Dimos J.T., Lemischka I.R., Studer L., Temple S. Bmi-1 cooperates with foxg1 to maintain neural stem cell self-renewal in the forebrain. Genes Dev 2009, 23:561-574.
-
(2009)
Genes Dev
, vol.23
, pp. 561-574
-
-
Fasano, C.A.1
Phoenix, T.N.2
Kokovay, E.3
Lowry, N.4
Elkabetz, Y.5
Dimos, J.T.6
Lemischka, I.R.7
Studer, L.8
Temple, S.9
-
73
-
-
70349349163
-
Reduction of seizures by transplantation of cortical gabaergic interneuron precursors into kv1.1 mutant mice
-
Baraban S.C., Southwell D.G., Estrada R.C., Jones D.L., Sebe J.Y., Alfaro-Cervello C., Garcia-Verdugo J.M., Rubenstein J.L., Alvarez-Buylla A. Reduction of seizures by transplantation of cortical gabaergic interneuron precursors into kv1.1 mutant mice. Proc Natl Acad Sci U S A 2009, 106:15472-15477.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 15472-15477
-
-
Baraban, S.C.1
Southwell, D.G.2
Estrada, R.C.3
Jones, D.L.4
Sebe, J.Y.5
Alfaro-Cervello, C.6
Garcia-Verdugo, J.M.7
Rubenstein, J.L.8
Alvarez-Buylla, A.9
-
74
-
-
77449150622
-
Embryonic mge precursor cells grafted into adult rat striatum integrate and ameliorate motor symptoms in 6-ohda-lesioned rats
-
Martinez-Cerdeno V., Noctor S.C., Espinosa A., Ariza J., Parker P., Orasji S., Daadi M.M., Bankiewicz K., Alvarez-Buylla A., Kriegstein A.R. Embryonic mge precursor cells grafted into adult rat striatum integrate and ameliorate motor symptoms in 6-ohda-lesioned rats. Cell Stem Cell 2010, 6:238-250.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 238-250
-
-
Martinez-Cerdeno, V.1
Noctor, S.C.2
Espinosa, A.3
Ariza, J.4
Parker, P.5
Orasji, S.6
Daadi, M.M.7
Bankiewicz, K.8
Alvarez-Buylla, A.9
Kriegstein, A.R.10
|