메뉴 건너뛰기




Volumn 6, Issue 5, 2011, Pages

Mitochondrial changes in ageing caenorhabditis elegans - what do we learn from superoxide dismutase knockouts?

Author keywords

[No Author keywords available]

Indexed keywords

FREE RADICAL; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; SUPEROXIDE;

EID: 79956189909     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019444     Document Type: Article
Times cited : (79)

References (80)
  • 1
    • 34249672703 scopus 로고    scopus 로고
    • Biological aging is no longer an unsolved problem
    • Hayflick L, (2007) Biological aging is no longer an unsolved problem. Ann N Y Acad Sci 1100: 1-13.
    • (2007) Ann N Y Acad Sci , vol.1100 , pp. 1-13
    • Hayflick, L.1
  • 2
    • 33744490096 scopus 로고    scopus 로고
    • Aging is no longer an unsolved problem in biology
    • Holliday R, (2006) Aging is no longer an unsolved problem in biology. Ann N Y Acad Sci 1067: 1-9.
    • (2006) Ann N Y Acad Sci , vol.1067 , pp. 1-9
    • Holliday, R.1
  • 3
    • 0025196557 scopus 로고
    • Slow mortality rate accelerations during aging in some animals approximate that of humans
    • Finch CE, Pike MC, Witten M, (1990) Slow mortality rate accelerations during aging in some animals approximate that of humans. Science 249: 902-905.
    • (1990) Science , vol.249 , pp. 902-905
    • Finch, C.E.1    Pike, M.C.2    Witten, M.3
  • 5
    • 0024541837 scopus 로고
    • Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases
    • Linnane AW, Marzuki S, Ozawa T, Tanaka M, (1989) Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases. Lancet 1: 642-645.
    • (1989) Lancet , vol.1 , pp. 642-645
    • Linnane, A.W.1    Marzuki, S.2    Ozawa, T.3    Tanaka, M.4
  • 6
    • 0015319592 scopus 로고
    • The biologic clock: the mitochondria?
    • Harman D, (1972) The biologic clock: the mitochondria? J Am Geriatr Soc 20: 145-147.
    • (1972) J Am Geriatr Soc , vol.20 , pp. 145-147
    • Harman, D.1
  • 7
    • 77049308856 scopus 로고
    • Aging: a theory based on free radical and radiation chemistry
    • Harman D, (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 11: 298-300.
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 8
    • 0035930837 scopus 로고    scopus 로고
    • The reliability theory of aging and longevity
    • Gavrilov LA, Gavrilova NS, (2001) The reliability theory of aging and longevity. J Theor Biol 213: 527-545.
    • (2001) J Theor Biol , vol.213 , pp. 527-545
    • Gavrilov, L.A.1    Gavrilova, N.S.2
  • 9
    • 0029890534 scopus 로고    scopus 로고
    • A network theory of ageing: the interactions of defective mitochondria, aberrant proteins, free radicals and scavengers in the ageing process
    • Kowald A, Kirkwood TB, (1996) A network theory of ageing: the interactions of defective mitochondria, aberrant proteins, free radicals and scavengers in the ageing process. Mutat Res 316: 209-236.
    • (1996) Mutat Res , vol.316 , pp. 209-236
    • Kowald, A.1    Kirkwood, T.B.2
  • 10
    • 0025309791 scopus 로고
    • Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?
    • Bandy B, Davison AJ, (1990) Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging? Free Radic Biol Med 8: 523-539.
    • (1990) Free Radic Biol Med , vol.8 , pp. 523-539
    • Bandy, B.1    Davison, A.J.2
  • 12
    • 78149343508 scopus 로고    scopus 로고
    • Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship?
    • Van Raamsdonk JM, Hekimi S, (2010) Reactive Oxygen Species and Aging in Caenorhabditis elegans: Causal or Casual Relationship? Antioxid Redox Signal 13: 1911-1953.
    • (2010) Antioxid Redox Signal , vol.13 , pp. 1911-1953
    • van Raamsdonk, J.M.1    Hekimi, S.2
  • 13
    • 50249094970 scopus 로고    scopus 로고
    • The mitochondrial free radical theory of ageing-where do we stand?
    • Gruber J, Schaffer S, Halliwell B, (2008) The mitochondrial free radical theory of ageing-where do we stand? Front Biosci 13: 6554-6579.
    • (2008) Front Biosci , vol.13 , pp. 6554-6579
    • Gruber, J.1    Schaffer, S.2    Halliwell, B.3
  • 14
    • 70350660932 scopus 로고    scopus 로고
    • Ageing and oxidants in the nematode Caenorhabditis elegans
    • Gems D, (2009) Ageing and oxidants in the nematode Caenorhabditis elegans. SEB Exp Biol Ser 62: 31-56.
    • (2009) SEB Exp Biol Ser , vol.62 , pp. 31-56
    • Gems, D.1
  • 15
    • 18744416025 scopus 로고    scopus 로고
    • Quantification of random genomic mutations
    • Bielas JH, Loeb LA, (2005) Quantification of random genomic mutations. Nat Methods 2: 285-290.
    • (2005) Nat Methods , vol.2 , pp. 285-290
    • Bielas, J.H.1    Loeb, L.A.2
  • 16
    • 70350676299 scopus 로고    scopus 로고
    • Deceptively simple but simply deceptive-Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects
    • Gruber J, Ng LF, Poovathingal SK, Halliwell B, (2009) Deceptively simple but simply deceptive-Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects. FEBS Lett 583: 3377-3387.
    • (2009) FEBS Lett , vol.583 , pp. 3377-3387
    • Gruber, J.1    Ng, L.F.2    Poovathingal, S.K.3    Halliwell, B.4
  • 17
    • 0023678537 scopus 로고
    • Three mutants that extend both mean and maximum life span of the nematode, Caenorhabditis elegans, define the age-1 gene
    • Friedman DB, Johnson TE, (1988) Three mutants that extend both mean and maximum life span of the nematode, Caenorhabditis elegans, define the age-1 gene. J Gerontol 43: B102-109.
    • (1988) J Gerontol , vol.43 , pp. 102-109
    • Friedman, D.B.1    Johnson, T.E.2
  • 18
    • 13944269223 scopus 로고    scopus 로고
    • The plasticity of aging: insights from long-lived mutants
    • Kenyon C, (2005) The plasticity of aging: insights from long-lived mutants. Cell 120: 449-460.
    • (2005) Cell , vol.120 , pp. 449-460
    • Kenyon, C.1
  • 19
    • 33748556296 scopus 로고    scopus 로고
    • Age-related changes of mitochondrial structure and function in Caenorhabditis elegans
    • Yasuda K, Ishii T, Suda H, Akatsuka A, Hartman PS, et al. (2006) Age-related changes of mitochondrial structure and function in Caenorhabditis elegans. Mech Ageing Dev 127: 763-770.
    • (2006) Mech Ageing Dev , vol.127 , pp. 763-770
    • Yasuda, K.1    Ishii, T.2    Suda, H.3    Akatsuka, A.4    Hartman, P.S.5
  • 20
    • 16244381751 scopus 로고    scopus 로고
    • Direct measurement of oxygen consumption rate on the nematode Caenorhabditis elegans by using an optical technique
    • Suda H, Shouyama T, Yasuda K, Ishii N, (2005) Direct measurement of oxygen consumption rate on the nematode Caenorhabditis elegans by using an optical technique. Biochem Biophys Res Commun 330: 839-843.
    • (2005) Biochem Biophys Res Commun , vol.330 , pp. 839-843
    • Suda, H.1    Shouyama, T.2    Yasuda, K.3    Ishii, N.4
  • 22
    • 0028228780 scopus 로고
    • Rapid accumulation of fluorescent material with aging in an oxygen-sensitive mutant mev-1 of Caenorhabditis elegans
    • Hosokawa H, Ishii N, Ishida H, Ichimori K, Nakazawa H, et al. (1994) Rapid accumulation of fluorescent material with aging in an oxygen-sensitive mutant mev-1 of Caenorhabditis elegans. Mech Ageing Dev 74: 161-170.
    • (1994) Mech Ageing Dev , vol.74 , pp. 161-170
    • Hosokawa, H.1    Ishii, N.2    Ishida, H.3    Ichimori, K.4    Nakazawa, H.5
  • 23
    • 23844436700 scopus 로고    scopus 로고
    • In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans
    • Gerstbrein B, Stamatas G, Kollias N, Driscoll M, (2005) In vivo spectrofluorimetry reveals endogenous biomarkers that report healthspan and dietary restriction in Caenorhabditis elegans. Aging Cell 4: 127-137.
    • (2005) Aging Cell , vol.4 , pp. 127-137
    • Gerstbrein, B.1    Stamatas, G.2    Kollias, N.3    Driscoll, M.4
  • 24
    • 66749126389 scopus 로고    scopus 로고
    • Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong?
    • Gems D, Doonan R, (2009) Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong? Cell Cycle 8: 1681-1687.
    • (2009) Cell Cycle , vol.8 , pp. 1681-1687
    • Gems, D.1    Doonan, R.2
  • 25
    • 0031904566 scopus 로고    scopus 로고
    • Effects of oxygen on protein carbonyl and aging in Caenorhabditis elegans mutants with long (age-1) and short (mev-1) life spans
    • Adachi H, Fujiwara Y, Ishii N, (1998) Effects of oxygen on protein carbonyl and aging in Caenorhabditis elegans mutants with long (age-1) and short (mev-1) life spans. J Gerontol A Biol Sci Med Sci 53: B240-244.
    • (1998) J Gerontol A Biol Sci Med Sci , vol.53 , pp. 240-244
    • Adachi, H.1    Fujiwara, Y.2    Ishii, N.3
  • 26
    • 0014410114 scopus 로고
    • The reduction of cytochrome c by milk xanthine oxidase
    • McCord JM, Fridovich I, (1968) The reduction of cytochrome c by milk xanthine oxidase. J Biol Chem 243: 5753-5760.
    • (1968) J Biol Chem , vol.243 , pp. 5753-5760
    • McCord, J.M.1    Fridovich, I.2
  • 27
    • 77953358884 scopus 로고    scopus 로고
    • Effects of sod gene overexpression and deletion mutation on the expression profiles of reporter genes of major detoxification pathways in Caenorhabditis elegans
    • Back P, Matthijssens F, Vlaeminck C, Braeckman BP, Vanfleteren JR, (2010) Effects of sod gene overexpression and deletion mutation on the expression profiles of reporter genes of major detoxification pathways in Caenorhabditis elegans. Exp Gerontol 45: 603-610.
    • (2010) Exp Gerontol , vol.45 , pp. 603-610
    • Back, P.1    Matthijssens, F.2    Vlaeminck, C.3    Braeckman, B.P.4    Vanfleteren, J.R.5
  • 28
    • 57749095081 scopus 로고    scopus 로고
    • Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans
    • Doonan R, McElwee JJ, Matthijssens F, Walker GA, Houthoofd K, et al. (2008) Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans. Genes Dev 22: 3236-3241.
    • (2008) Genes Dev , vol.22 , pp. 3236-3241
    • Doonan, R.1    McElwee, J.J.2    Matthijssens, F.3    Walker, G.A.4    Houthoofd, K.5
  • 29
    • 43649105922 scopus 로고    scopus 로고
    • Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like signaling control in Caenorhabditis elegans
    • Honda Y, Tanaka M, Honda S, (2008) Modulation of longevity and diapause by redox regulation mechanisms under the insulin-like signaling control in Caenorhabditis elegans. Exp Gerontol 43: 520-529.
    • (2008) Exp Gerontol , vol.43 , pp. 520-529
    • Honda, Y.1    Tanaka, M.2    Honda, S.3
  • 30
    • 61449184625 scopus 로고    scopus 로고
    • Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans
    • Van Raamsdonk JM, Hekimi S, (2009) Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans. PLoS Genet 5: e1000361.
    • (2009) PLoS Genet , vol.5
    • van Raamsdonk, J.M.1    Hekimi, S.2
  • 31
    • 37249016870 scopus 로고    scopus 로고
    • A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans
    • Yang W, Li J, Hekimi S, (2007) A Measurable increase in oxidative damage due to reduction in superoxide detoxification fails to shorten the life span of long-lived mitochondrial mutants of Caenorhabditis elegans. Genetics 177: 2063-2074.
    • (2007) Genetics , vol.177 , pp. 2063-2074
    • Yang, W.1    Li, J.2    Hekimi, S.3
  • 32
    • 75149165994 scopus 로고    scopus 로고
    • Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging?
    • Salmon AB, Richardson A, Perez VI, (2010) Update on the oxidative stress theory of aging: does oxidative stress play a role in aging or healthy aging? Free Radic Biol Med 48: 642-655.
    • (2010) Free Radic Biol Med , vol.48 , pp. 642-655
    • Salmon, A.B.1    Richardson, A.2    Perez, V.I.3
  • 33
    • 73749085674 scopus 로고    scopus 로고
    • When a theory of aging ages badly
    • Lapointe J, Hekimi S, (2009) When a theory of aging ages badly. Cell Mol Life Sci 67: 1-8.
    • (2009) Cell Mol Life Sci , vol.67 , pp. 1-8
    • Lapointe, J.1    Hekimi, S.2
  • 34
    • 78650455712 scopus 로고    scopus 로고
    • A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans
    • Yang W, Hekimi S, (2010) A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. PLoS Biol 8: e1000556.
    • (2010) PLoS Biol , vol.8
    • Yang, W.1    Hekimi, S.2
  • 35
    • 31744450413 scopus 로고    scopus 로고
    • Alternative pathways as mechanism for the negative effects associated with overexpression of superoxide dismutase
    • Kowald A, Lehrach H, Klipp E, (2006) Alternative pathways as mechanism for the negative effects associated with overexpression of superoxide dismutase. J Theor Biol 238: 828-840.
    • (2006) J Theor Biol , vol.238 , pp. 828-840
    • Kowald, A.1    Lehrach, H.2    Klipp, E.3
  • 36
    • 34247109461 scopus 로고    scopus 로고
    • The effects of superoxide dismutase on H2O2 formation
    • Liochev SI, Fridovich I, (2007) The effects of superoxide dismutase on H2O2 formation. Free Radic Biol Med 42: 1465-1469.
    • (2007) Free Radic Biol Med , vol.42 , pp. 1465-1469
    • Liochev, S.I.1    Fridovich, I.2
  • 37
    • 0037096203 scopus 로고    scopus 로고
    • Why does SOD overexpression sometimes enhance, sometimes decrease, hydrogen peroxide production? A minimalist explanation
    • Gardner R, Salvador A, Moradas-Ferreira P, (2002) Why does SOD overexpression sometimes enhance, sometimes decrease, hydrogen peroxide production? A minimalist explanation. Free Radic Biol Med 32: 1351-1357.
    • (2002) Free Radic Biol Med , vol.32 , pp. 1351-1357
    • Gardner, R.1    Salvador, A.2    Moradas-Ferreira, P.3
  • 38
    • 0036628738 scopus 로고    scopus 로고
    • Superoxide and nitric oxide: consequences of varying rates of production and consumption: a theoretical treatment
    • Liochev SI, Fridovich I, (2002) Superoxide and nitric oxide: consequences of varying rates of production and consumption: a theoretical treatment. Free Radic Biol Med 33: 137-141.
    • (2002) Free Radic Biol Med , vol.33 , pp. 137-141
    • Liochev, S.I.1    Fridovich, I.2
  • 39
    • 27544439179 scopus 로고    scopus 로고
    • Metabolism in the Caenorhabditis elegans Mit mutants
    • Rea SL, (2005) Metabolism in the Caenorhabditis elegans Mit mutants. Exp Gerontol 40: 841-849.
    • (2005) Exp Gerontol , vol.40 , pp. 841-849
    • Rea, S.L.1
  • 40
    • 0037167855 scopus 로고    scopus 로고
    • Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans
    • Herndon LA, Schmeissner PJ, Dudaronek JM, Brown PA, Listner KM, et al. (2002) Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 419: 808-814.
    • (2002) Nature , vol.419 , pp. 808-814
    • Herndon, L.A.1    Schmeissner, P.J.2    Dudaronek, J.M.3    Brown, P.A.4    Listner, K.M.5
  • 41
    • 79958151915 scopus 로고    scopus 로고
    • The effect of dichloroacetate on health- and lifespan in C. elegans
    • [Epub ahead of print]
    • Schaffer S, Gruber J, Ng LF, Fong S, Wong YT, et al. (2010) The effect of dichloroacetate on health- and lifespan in C. elegans. Biogerontology [Epub ahead of print].
    • (2010) Biogerontology
    • Schaffer, S.1    Gruber, J.2    Ng, L.F.3    Fong, S.4    Wong, Y.T.5
  • 42
    • 76249101649 scopus 로고    scopus 로고
    • The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity
    • Alper S, McElwee MK, Apfeld J, Lackford B, Freedman JH, et al. (2010) The Caenorhabditis elegans germ line regulates distinct signaling pathways to control lifespan and innate immunity. J Biol Chem 285: 1822-1828.
    • (2010) J Biol Chem , vol.285 , pp. 1822-1828
    • Alper, S.1    McElwee, M.K.2    Apfeld, J.3    Lackford, B.4    Freedman, J.H.5
  • 43
    • 77955596719 scopus 로고    scopus 로고
    • C. elegans germline-deficient mutants respond to pathogen infection using shared and distinct mechanisms
    • TeKippe M, Aballay A, (2010) C. elegans germline-deficient mutants respond to pathogen infection using shared and distinct mechanisms. PLoS One 5: e11777.
    • (2010) PLoS One , vol.5
    • TeKippe, M.1    Aballay, A.2
  • 44
    • 34548307297 scopus 로고    scopus 로고
    • Basic principle of the lifespan in the nematode C. elegans
    • Shoyama T, Ozaki T, Ishii N, Yokota S, Suda H, (2007) Basic principle of the lifespan in the nematode C. elegans. Mech Ageing Dev 128: 529-537.
    • (2007) Mech Ageing Dev , vol.128 , pp. 529-537
    • Shoyama, T.1    Ozaki, T.2    Ishii, N.3    Yokota, S.4    Suda, H.5
  • 45
    • 70449701423 scopus 로고    scopus 로고
    • Decline in oxygen consumption correlates with lifespan in long-lived and short-lived mutants of Caenorhabditis elegans
    • Shoyama T, Shimizu Y, Suda H, (2009) Decline in oxygen consumption correlates with lifespan in long-lived and short-lived mutants of Caenorhabditis elegans. Exp Gerontol 44: 784-791.
    • (2009) Exp Gerontol , vol.44 , pp. 784-791
    • Shoyama, T.1    Shimizu, Y.2    Suda, H.3
  • 46
    • 77953924893 scopus 로고    scopus 로고
    • Disruption of insulin signalling preserves bioenergetic competence of mitochondria in ageing Caenorhabditis elegans
    • Brys K, Castelein N, Matthijssens F, Vanfleteren JR, Braeckman BP, (2010) Disruption of insulin signalling preserves bioenergetic competence of mitochondria in ageing Caenorhabditis elegans. BMC Biol 8: 91.
    • (2010) BMC Biol , vol.8 , pp. 91
    • Brys, K.1    Castelein, N.2    Matthijssens, F.3    Vanfleteren, J.R.4    Braeckman, B.P.5
  • 47
    • 70349957947 scopus 로고    scopus 로고
    • Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans
    • Artal-Sanz M, Tavernarakis N, (2009) Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans. Nature 461: 793-797.
    • (2009) Nature , vol.461 , pp. 793-797
    • Artal-Sanz, M.1    Tavernarakis, N.2
  • 48
    • 34748829513 scopus 로고    scopus 로고
    • Effects of the flavonoids kaempferol and fisetin on thermotolerance, oxidative stress and FoxO transcription factor DAF-16 in the model organism Caenorhabditis elegans
    • Kampkotter A, Gombitang Nkwonkam C, Zurawski RF, Timpel C, Chovolou Y, et al. (2007) Effects of the flavonoids kaempferol and fisetin on thermotolerance, oxidative stress and FoxO transcription factor DAF-16 in the model organism Caenorhabditis elegans. Arch Toxicol 81: 849-858.
    • (2007) Arch Toxicol , vol.81 , pp. 849-858
    • Kampkotter, A.1    Gombitang Nkwonkam, C.2    Zurawski, R.F.3    Timpel, C.4    Chovolou, Y.5
  • 49
    • 1842685103 scopus 로고    scopus 로고
    • Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products
    • Headlam HA, Davies MJ, (2004) Markers of protein oxidation: different oxidants give rise to variable yields of bound and released carbonyl products. Free Radic Biol Med 36: 1175-1184.
    • (2004) Free Radic Biol Med , vol.36 , pp. 1175-1184
    • Headlam, H.A.1    Davies, M.J.2
  • 50
    • 33747879504 scopus 로고    scopus 로고
    • Why does superoxide dismutase overexpression often increase hydrogen peroxide concentrations? An alternative explanation
    • Gardner R, Moradas-Ferreira P, Salvador A, (2006) Why does superoxide dismutase overexpression often increase hydrogen peroxide concentrations? An alternative explanation. J Theor Biol 242: 798-800.
    • (2006) J Theor Biol , vol.242 , pp. 798-800
    • Gardner, R.1    Moradas-Ferreira, P.2    Salvador, A.3
  • 51
    • 4344645827 scopus 로고    scopus 로고
    • The redox regulation of intermediary metabolism by a superoxide-aconitase rheostat
    • Armstrong JS, Whiteman M, Yang H, Jones DP, (2004) The redox regulation of intermediary metabolism by a superoxide-aconitase rheostat. Bioessays 26: 894-900.
    • (2004) Bioessays , vol.26 , pp. 894-900
    • Armstrong, J.S.1    Whiteman, M.2    Yang, H.3    Jones, D.P.4
  • 52
    • 0033785071 scopus 로고    scopus 로고
    • Uncoupling to survive? The role of mitochondrial inefficiency in ageing
    • Brand MD, (2000) Uncoupling to survive? The role of mitochondrial inefficiency in ageing. Exp Gerontol 35: 811-820.
    • (2000) Exp Gerontol , vol.35 , pp. 811-820
    • Brand, M.D.1
  • 53
    • 24344491154 scopus 로고    scopus 로고
    • Examination of the requirement for ucp-4, a putative homolog of mammalian uncoupling proteins, for stress tolerance and longevity in C. elegans
    • Iser WB, Kim D, Bachman E, Wolkow C, (2005) Examination of the requirement for ucp-4, a putative homolog of mammalian uncoupling proteins, for stress tolerance and longevity in C. elegans. Mech Ageing Dev 126: 1090-1096.
    • (2005) Mech Ageing Dev , vol.126 , pp. 1090-1096
    • Iser, W.B.1    Kim, D.2    Bachman, E.3    Wolkow, C.4
  • 54
    • 0030881686 scopus 로고    scopus 로고
    • Oxidative damage during aging targets mitochondrial aconitase
    • Yan LJ, Levine RL, Sohal RS, (1997) Oxidative damage during aging targets mitochondrial aconitase. Proc Natl Acad Sci U S A 94: 11168-11172.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 11168-11172
    • Yan, L.J.1    Levine, R.L.2    Sohal, R.S.3
  • 55
    • 0032573066 scopus 로고    scopus 로고
    • Mitochondrial adenine nucleotide translocase is modified oxidatively during aging
    • Yan LJ, Sohal RS, (1998) Mitochondrial adenine nucleotide translocase is modified oxidatively during aging. Proc Natl Acad Sci U S A 95: 12896-12901.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 12896-12901
    • Yan, L.J.1    Sohal, R.S.2
  • 56
    • 0030783602 scopus 로고    scopus 로고
    • Inactivation of dehydratase [4Fe-4S] clusters and disruption of iron homeostasis upon cell exposure to peroxynitrite
    • Keyer K, Imlay JA, (1997) Inactivation of dehydratase [4Fe-4S] clusters and disruption of iron homeostasis upon cell exposure to peroxynitrite. J Biol Chem 272: 27652-27659.
    • (1997) J Biol Chem , vol.272 , pp. 27652-27659
    • Keyer, K.1    Imlay, J.A.2
  • 58
    • 76049115685 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans
    • Dingley S, Polyak E, Lightfoot R, Ostrovsky J, Rao M, et al. (2010) Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans. Mitochondrion 10: 125-136.
    • (2010) Mitochondrion , vol.10 , pp. 125-136
    • Dingley, S.1    Polyak, E.2    Lightfoot, R.3    Ostrovsky, J.4    Rao, M.5
  • 60
    • 67349229199 scopus 로고    scopus 로고
    • C. elegans longevity pathways converge to decrease mitochondrial membrane potential
    • Lemire BD, Behrendt M, DeCorby A, Gaskova D, (2009) C. elegans longevity pathways converge to decrease mitochondrial membrane potential. Mech Ageing Dev 130: 461-465.
    • (2009) Mech Ageing Dev , vol.130 , pp. 461-465
    • Lemire, B.D.1    Behrendt, M.2    DeCorby, A.3    Gaskova, D.4
  • 61
    • 0035957755 scopus 로고    scopus 로고
    • Mitochondrial uncoupling proteins and phylogenesis-UCP4 as the ancestral uncoupling protein
    • Hanak P, Jezek P, (2001) Mitochondrial uncoupling proteins and phylogenesis-UCP4 as the ancestral uncoupling protein. FEBS Lett 495: 137-141.
    • (2001) FEBS Lett , vol.495 , pp. 137-141
    • Hanak, P.1    Jezek, P.2
  • 62
    • 4043147798 scopus 로고    scopus 로고
    • Mitochondrial superoxide: production, biological effects and activation of uncoupling proteins
    • Brand MD, Affourtit C, Esteves TC, Green K, Lambert AJ, et al. (2004) Mitochondrial superoxide: production, biological effects and activation of uncoupling proteins. Free Radic Biol Med 37: 755-767.
    • (2004) Free Radic Biol Med , vol.37 , pp. 755-767
    • Brand, M.D.1    Affourtit, C.2    Esteves, T.C.3    Green, K.4    Lambert, A.J.5
  • 63
    • 0035956929 scopus 로고    scopus 로고
    • Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis
    • Kokoszka JE, Coskun P, Esposito LA, Wallace DC, (2001) Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis. Proc Natl Acad Sci U S A 98: 2278-2283.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 2278-2283
    • Kokoszka, J.E.1    Coskun, P.2    Esposito, L.A.3    Wallace, D.C.4
  • 64
    • 0029838063 scopus 로고    scopus 로고
    • Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice
    • Lebovitz RM, Zhang H, Vogel H, Cartwright J Jr, Dionne L, et al. (1996) Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. Proc Natl Acad Sci U S A 93: 9782-9787.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 9782-9787
    • Lebovitz, R.M.1    Zhang, H.2    Vogel, H.3    Cartwright Jr., J.4    Dionne, L.5
  • 65
    • 77953557616 scopus 로고    scopus 로고
    • 2′,7′-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy
    • Chen X, Zhong Z, Xu Z, Chen L, Wang Y, (2010) 2′,7′-Dichlorodihydrofluorescein as a fluorescent probe for reactive oxygen species measurement: Forty years of application and controversy. Free Radic Res 44: 587-604.
    • (2010) Free Radic Res , vol.44 , pp. 587-604
    • Chen, X.1    Zhong, Z.2    Xu, Z.3    Chen, L.4    Wang, Y.5
  • 66
    • 77952573307 scopus 로고    scopus 로고
    • What does the commonly used DCF test for oxidative stress really show?
    • Karlsson M, Kurz T, Brunk UT, Nilsson SE, Frennesson CI, (2010) What does the commonly used DCF test for oxidative stress really show? Biochem J 428: 183-190.
    • (2010) Biochem J , vol.428 , pp. 183-190
    • Karlsson, M.1    Kurz, T.2    Brunk, U.T.3    Nilsson, S.E.4    Frennesson, C.I.5
  • 67
    • 44949142269 scopus 로고    scopus 로고
    • The selective detection of mitochondrial superoxide by live cell imaging
    • Robinson KM, Janes MS, Beckman JS, (2008) The selective detection of mitochondrial superoxide by live cell imaging. Nat Protoc 3: 941-947.
    • (2008) Nat Protoc , vol.3 , pp. 941-947
    • Robinson, K.M.1    Janes, M.S.2    Beckman, J.S.3
  • 68
    • 65549169003 scopus 로고    scopus 로고
    • SOD-1 deletions in Caenorhabditis elegans alter the localization of intracellular reactive oxygen species and show molecular compensation
    • Yanase S, Onodera A, Tedesco P, Johnson TE, Ishii N, (2009) SOD-1 deletions in Caenorhabditis elegans alter the localization of intracellular reactive oxygen species and show molecular compensation. J Gerontol A Biol Sci Med Sci 64: 530-539.
    • (2009) J Gerontol A Biol Sci Med Sci , vol.64 , pp. 530-539
    • Yanase, S.1    Onodera, A.2    Tedesco, P.3    Johnson, T.E.4    Ishii, N.5
  • 69
    • 78751634983 scopus 로고    scopus 로고
    • Interrelationships between mitochondrial fusion, energy metabolism and oxidative stress during development in Caenorhabditis elegans
    • Yasuda K, Hartman PS, Ishii T, Suda H, Akatsuka A, et al. (2011) Interrelationships between mitochondrial fusion, energy metabolism and oxidative stress during development in Caenorhabditis elegans. Biochem Biophys Res Commun 404: 751-755.
    • (2011) Biochem Biophys Res Commun , vol.404 , pp. 751-755
    • Yasuda, K.1    Hartman, P.S.2    Ishii, T.3    Suda, H.4    Akatsuka, A.5
  • 70
    • 77955280004 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a model system for mtDNA replication defects
    • Bratic I, Hench J, Trifunovic A, (2010) Caenorhabditis elegans as a model system for mtDNA replication defects. Methods 51: 437-443.
    • (2010) Methods , vol.51 , pp. 437-443
    • Bratic, I.1    Hench, J.2    Trifunovic, A.3
  • 71
    • 38449085292 scopus 로고    scopus 로고
    • Maintenance of C. elegans
    • Stiernagle T, (2006) Maintenance of C. elegans. Worm Book pp. 1-11.
    • (2006) Worm Book , pp. 1-11
    • Stiernagle, T.1
  • 72
    • 0029019546 scopus 로고
    • Increased frequency of deletions in the mitochondrial genome with age of Caenorhabditis elegans
    • Melov S, Lithgow GJ, Fischer DR, Tedesco PM, Johnson TE, (1995) Increased frequency of deletions in the mitochondrial genome with age of Caenorhabditis elegans. Nucleic Acids Res 23: 1419-1425.
    • (1995) Nucleic Acids Res , vol.23 , pp. 1419-1425
    • Melov, S.1    Lithgow, G.J.2    Fischer, D.R.3    Tedesco, P.M.4    Johnson, T.E.5
  • 73
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ, (1959) A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917.
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 74
    • 34548388923 scopus 로고    scopus 로고
    • Sensitive profiling of chemically diverse bioactive lipids
    • Shui G, Bendt AK, Pethe K, Dick T, Wenk MR, (2007) Sensitive profiling of chemically diverse bioactive lipids. J Lipid Res 48: 1976-1984.
    • (2007) J Lipid Res , vol.48 , pp. 1976-1984
    • Shui, G.1    Bendt, A.K.2    Pethe, K.3    Dick, T.4    Wenk, M.R.5
  • 75
    • 77957814983 scopus 로고    scopus 로고
    • Characterization of substrate preference for Slc1p and Cst26p in Saccharomyces cerevisiae using lipidomic approaches and an LPAAT activity assay
    • Shui G, Guan XL, Gopalakrishnan P, Xue Y, Goh JS, et al. (2010) Characterization of substrate preference for Slc1p and Cst26p in Saccharomyces cerevisiae using lipidomic approaches and an LPAAT activity assay. PLoS One 5.
    • (2010) PLoS One , vol.5
    • Shui, G.1    Guan, X.L.2    Gopalakrishnan, P.3    Xue, Y.4    Goh, J.S.5
  • 76
    • 55549118226 scopus 로고    scopus 로고
    • Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides
    • Chan R, Uchil PD, Jin J, Shui G, Ott DE, et al. (2008) Retroviruses human immunodeficiency virus and murine leukemia virus are enriched in phosphoinositides. J Virol 82: 11228-11238.
    • (2008) J Virol , vol.82 , pp. 11228-11238
    • Chan, R.1    Uchil, P.D.2    Jin, J.3    Shui, G.4    Ott, D.E.5
  • 77
    • 0033796250 scopus 로고    scopus 로고
    • Mitochondrial free radical generation, oxidative stress, and aging
    • Cadenas E, Davies KJ, (2000) Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med 29: 222-230.
    • (2000) Free Radic Biol Med , vol.29 , pp. 222-230
    • Cadenas, E.1    Davies, K.J.2
  • 78
    • 0030939089 scopus 로고    scopus 로고
    • On the virtual existence of superoxide anions in mitochondria: thoughts regarding its role in pathophysiology
    • Forman HJ, Azzi A, (1997) On the virtual existence of superoxide anions in mitochondria: thoughts regarding its role in pathophysiology. Faseb J 11: 374-375.
    • (1997) Faseb J , vol.11 , pp. 374-375
    • Forman, H.J.1    Azzi, A.2
  • 79
    • 21544480278 scopus 로고    scopus 로고
    • Immunohistochemical determination of cytosolic cytochrome C concentration in cardiomyocytes
    • van Beek-Harmsen BJ, van der Laarse WJ, (2005) Immunohistochemical determination of cytosolic cytochrome C concentration in cardiomyocytes. J Histochem Cytochem 53: 803-807.
    • (2005) J Histochem Cytochem , vol.53 , pp. 803-807
    • van Beek-Harmsen, B.J.1    van der Laarse, W.J.2
  • 80
    • 68149169007 scopus 로고    scopus 로고
    • What is the real physiological NO concentration in vivo?
    • Hall CN, Garthwaite J, (2009) What is the real physiological NO concentration in vivo? Nitric Oxide 21: 92-103.
    • (2009) Nitric Oxide , vol.21 , pp. 92-103
    • Hall, C.N.1    Garthwaite, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.