2-(2-Fluorobenzamido)benzoate ethyl ester (EFB-1) inhibits superoxide production by human neutrophils and attenuates hemorrhagic shock-induced organ dysfunction in rats

Free Radical Biology and Medicine

Volumn 50, Issue 12, 2011, Pages 1737-1748

  Yu, Huang Ping ^a,b   Hsieh, Pei Wen ^b   Chang, Yi Ju ^b   Chung, Pei Jen ^b   Kuo, Liang Mou ^a   Hwang, Tsong Long ^b  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

Author keywords

2 (2 Fluorobenzamido)benzoic acid ethyl ester; Free radicals; Multiple organ dysfunction; Neutrophils; Phosphodiesterase; Superoxide anion; Trauma hemorrhagic shock

Indexed keywords

2 (2 FLUOROBENZAMIDO)BENZOATE ETHYL ESTER; ADENYLATE CYCLASE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CD11B ANTIGEN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; KT 5720; MYELOPEROXIDASE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; OXYGEN RADICAL; PHOSPHODIESTERASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE INHIBITOR; SUPEROXIDE; UNCLASSIFIED DRUG;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANION TRANSPORT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CALCIUM MOBILIZATION; CELL ACTIVATION; CONTROLLED STUDY; DRY WEIGHT; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HEMORRHAGIC SHOCK; HUMAN; MULTIPLE ORGAN FAILURE; NEUTROPHIL; PKA; PRIORITY JOURNAL;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; ADENYLATE CYCLASE; ANIMALS; ANTIGENS, CD11B; BENZAMIDES; BENZOATES; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FREE RADICALS; HUMANS; INTESTINES; LEUKOCYTE ELASTASE; LIVER; LUNG INJURY; MULTIPLE ORGAN FAILURE; NEUTROPHIL ACTIVATION; NEUTROPHILS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SHOCK, HEMORRHAGIC; SUPEROXIDES;

RATTUS;

EID: 79956152545     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.03.026     Document Type: Article

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