The PGE2-induced inhibition of the PLD activation pathway stimulated by fMLP in human neutrophils is mediated by PKA at the PI3-Kγ level

Biochemical Pharmacology

Volumn 74, Issue 5, 2007, Pages 730-741

  Burelout, Chantal ^a   Thibault, Nathalie ^a   Harbour, Danielle ^a   Naccache, Paul H ^a   Bourgoin, Sylvain G ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

EP2 receptor; fMLP; PGE2; PI3 K ; PKA; PLD

Indexed keywords

ADENOSINE; FORMYLMETHIONYLLEUCYLPHENYLALANINE; GUANOSINE TRIPHOSPHATASE; INOSINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOLIPASE; PROSTAGLANDIN E2; THYROXINE; CALCIUM; CYCLIC AMP DEPENDENT PROTEIN KINASE; ISOENZYME; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PHOSPHATIDYLINOSITOL 3-KINASE GAMMA; PHOSPHOLIPASE D; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN EP2 RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM TRANSPORT; CELL ACTIVATION; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; NEUTROPHIL; PHOSPHORYLATION; PKA; PRIORITY JOURNAL; CELL CULTURE; DRUG ANTAGONISM; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CALCIUM; CELLS, CULTURED; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DINOPROSTONE; ENZYME ACTIVATION; HUMANS; ISOENZYMES; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; PHOSPHOLIPASE D; PHOSPHORYLATION; RECEPTORS, PROSTAGLANDIN E;

EID: 34447645517     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2007.06.013     Document Type: Article

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