Genotoxicity evaluation of nanomaterials: DNA damage, micronuclei, and 8-hydroxy-2-deoxyguanosine induced by magnetic doped CdSe quantum dots in male mice

Chemical Research in Toxicology

Volumn 24, Issue 5, 2011, Pages 640-650

  Khalil, W K B ^a   Girgis, E ^a   Emam, A N ^a   Mohamed, M B ^b   Rao, K V ^c  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b Cairo University   (Egypt)

^c ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CADMIUM SELENIDE; COBALT; NANOMATERIAL; QUANTUM DOT; THIOGLYCOLIC ACID; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BONE MARROW; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; GENOTOXICITY; IN VIVO STUDY; LIVER; MALE; MICRONUCLEUS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PARTICLE SIZE;

ANIMALS; CADMIUM COMPOUNDS; DEOXYGUANOSINE; DNA; DNA DAMAGE; MALE; MICE; MICRONUCLEUS TESTS; MUTAGENS; QUANTUM DOTS; SELENIUM COMPOUNDS;

MUS;

EID: 79956150475     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx2000015     Document Type: Article

References (72)

1. Bruchez, J. M., Moronne, M., Gin, P., Weiss, S., and Alivisatos, A. P. (1998) Semiconductor nanocrystals as fluorescent biological labels Science 281, 2013-2016 (Pubitemid 28475485)
2. Bentolila, L. A. (2009) Quantum dots for in vivo small-animal imaging J. Nucl. Med. 50, 4
3. Drbohlavova, J. (2009) Quantum dots: characterization, preparation and usage in biological systems Int. J. Mol. Sci. 10, 656-673
4. Chao, W., Xue, G., and Xingguang, S. (2010) Study the damage of DNA molecules induced by three kinds of aqueous nanoparticles Talanta 80, 1228-1233
5. Zhang, J. (2010) Fluorescent quantum dot-labeled aptamer bioprobes specifically targeting mouse liver cancer cells Talanta 81, 505-509
6. Smith, A. M. and Nie, S. M. (2004) Chemical analysis and cellular imaging with quantum dots Analyst 129, 672-677 (Pubitemid 39120509)
7. Ma, Q., Su, X. G., Wang, X. Y., Wan, Y., Wang, C. L., and Yang, B 2005, Fluorescence resonance energy transfer in doubly-quantum dot labeled IgG system Talanta 67, 1029-1034 (Pubitemid 41491932)
8. Michalet, X., Pinaud, F. F., Bentolila, L. A., Tsay, J. M., Doose, S., and Li, J. J. 2005, Quantum dots for live cells, in vivo imaging, and diagnostics Science 307, 538-544 (Pubitemid 40165671)
9. Liang, J., Huang, S., Zeng, D., He, Z., Ji, X., and Ai, X. 2006, CdSe quantum dots as luminescent probes for spironolactone determination Talanta 69, 126-130 (Pubitemid 43165513)
10. Chan, W. C. W. and Nie, S. (1998) Quantum dot bioconjugates for ultrasensitive nonisotopic detection Science 281, 2016-2018 (Pubitemid 28475486)
11. Weng, J., Song, X., Li, L., Qian, H., Chenb, K., and Xu, X. 2003, Functional hybrid devices of proteins and inorganic nanoparticles Talanta 42, 5796-5800
12. Wu, X. Y., Liu, H. J., Liu, J. Q., Haley, K. N., Treadway, J. A., and Larson, J. P. 2003, The application on binders in low vulnerability ammunition Nat. Biotechnol. 21, 41-42
13. Gao, X., Cui, Y., Levenson, R. M., Chung, L. W. K., and Nie, S. (2004) In vivo cancer targeting and imaging with semiconductor quantum dots Nat. Biotechnol. 22, 969-976 (Pubitemid 39014473)
14. Han, M., Gao, X., Su, J. Z., and Nie, S. (2001) Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules Nat. Biotechnol. 19, 631-635 (Pubitemid 32625432)
15. Jin, W. J., Fernandez-Arguelles, M. T., Costa-Fernandez, J. M., Pereiro, R., and Sanz-Medel, A. (2005) Photoactivated luminescent CdSe quantum dots as sensitive cyanide probes in aqueous solutions Chem. Commun. 883-885 (Pubitemid 40313263)
16. Lu, Q., Hu, S., Pang, D., and He, Z. (2005) Direct electrochemistry and electrocatalysis with hemoglobin in water-soluble quantum dots film on glassy carbon electrode Chem. Commun. 2584-2585 (Pubitemid 40825251)
17. Zhang, F., Li, C., Li, X., Wang, X., Wan, Q., and Xian, Y. 2006, ZnS quantum dots derived a reagentless uric acid biosensor Talanta 68, 1353-1358 (Pubitemid 43090835)
18. Liang, J., He, Z., Zhang, S., Huanga, S., Ai, X., and Yang, H. 2007, Study on DNA damage induced by CdSe quantum dots using nucleic acid molecular "light switches" as probe Talanta 71, 1675-1678 (Pubitemid 46282845)
19. Dubertret, B., Skourides, P., Norris, D. J., Noireaux, V., Brivanlou, A. H., and Libchaber, A. (2005) In vivo imaging of quantum dots encapsulated in phospholipid micelles Science 298, 1759-1762
20. Derfus, A. M., Chan, W. C. W., and Bhatia, S. N. (2004) Probing the cytotoxicity of semiconductor quantum dots Nano Lett. 4, 11-18 (Pubitemid 38167855)
21. Hoshino, A., Fujioka, K., Oku, T., Suga, M., Sasaki, Y. F., and Ohta, T. 2004, Physicochemical properties and cellular toxicity of nanocrystal quantum dots depend on their surface modification Nano Lett. 4, 2163-2169
22. Kirchner, C., Liedl, T., Kudera, S., Pellegrino, T., Javier, A. M., and Gaub, H. E. 2005, Cytotoxicity of colloidal. CdSe and CdSe/ZnS nanoparticles Nano Lett. 5, 331-338 (Pubitemid 40308295)
23. Lovrić, J., Bazzi, H. S., Cuie, Y., Fortin, G. R. A., Winnik, F. M., and Maysinger, D. (2005) Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots J. Mol. Med. 83, 377-385 (Pubitemid 41201802)
24. Green, M. and Howman, E. (2005) Semiconductor quantum dots and free radical induced DNA nicking Chem. Commun. 7, 121-123
25. Klimov, V. I. (2003) Nanocrystal Quantum Dots From fundamental photophysics to multicolor lasing Los Alamos Sci. 28) 214-220
26. Gmez, D. E., Embden, J. V., Jasieniak, J., Smith, T. A., and Mulvaney, P. (2006) Blinking and surface chemistry of single CdSe nanocrystals Small 2, 204-208 (Pubitemid 43204263)
27. Efros, A. (2002) Auger Processes in Nanosize Semiconductor Crystals, Naval Research Laboratory, Washington, DC.
28. Schmid, G. (2004) Nanoparticles: From Theory to Application, Vol. 8, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany.
29. Empedocles, S. A. and Bawendi, M. G. (1999) Influence of spectral diffusion on the line shapes of single CdSe nanocrystallite quantum dots J. Phys. Chem. B 103, 1826-1830 (Pubitemid 129702065)
30. Nirmal, M. and Brus, L. (1999) Luminescence photophysics in semiconductor nanocrystals Acc. Chem. Res. 32, 407-414
31. Mahler, B., Spincelli, P., Buil, S. P., Quelin, X., Hermier, J. P., and Dubertret, B. (2008) Towards non-blinking colloidal quantum dots Nat. Mater. 7, 660-664
32. Spinicelli, P., Mahler, B., Buil, S. P., Qu, Lin X., Dubertret, B., and Hermier, J. P. (2009) Non-blinking semiconductor colloidal quantum dots for biology, optoelectronics and quantum optics Chem. Phys. Chem. 10, 879-882
33. Yu, Z. H., Guo, L., Du, H., Krauss, T., and Silcox, J. (2005) Shell distribution on colloidal CdSe/ZnS quantum dots Nano Lett. 5, 565-570 (Pubitemid 40609721)
34. Murray, C. B., Norris, D. J., and Bawendi, M. G. (1993) Synthesis and characterization of nearly monodisperse CdE (E = S, Se, Te) semiconductor nanocrystallites J. Am. Chem. Soc. 115, 8706-8715
35. Peng, Z. A. and Peng, X. (2001) Formation of high-quality CdTe, CdSe, and CdS nanocrystals using CdO as precursor J. Am. Chem. Soc. 123, 183
36. Qu, L., Peng, Z. A., and Peng, X. (2001) Alternative routes toward high quality CdSe nanocrystals Nano Lett. 1, 333-337 (Pubitemid 33672983)
37. Mohamed, M. B., Tonti, D., Al-Salman, A., Chemseddine, A., and El-Chagui, M. (2005) Synthesis of high quality zinc-blende CdSe nanocrystals J. Phys. Chem. 10, 10533-10537 (Pubitemid 40844479)
38. The Organisation for Economic Co-operation and Development (2001) Guidelines 420: Acute Oral Toxicity: Fixed Dosed Procedure, December, 2001.
39. Burton, K. (1956) A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid Biochem. J. 62, 315-323
40. Lu, T., Xu, Y., Mericle, M. T., and Mellgren, R. L. (2002) Participation of the conventional calpains in apoptosis Biochim. Biophys. Acta 1590, 16-26 (Pubitemid 34626765)
41. Ueda, T., Hayashi, M., Koide, N., Sofuni, T., and Kobayashi, J. (1992) A preliminary study of the micronucleus test by acridine orange fluorescent staining compared with chromosomal aberration test using fish erythropoietic and embryonic cells Water Sci. Technol. 25, 235-240
42. Patel, M., Liang, L. P., and Roberts, L. J. (2001) Enhanced hippocampal F2-isoprostane formation following kainateinduced seizures J. Neurochem. 79, 1065-1069 (Pubitemid 33117087)
43. SAS (1982) SAS User'S Guide: Statistics Edition, SAS Institute Inc., Cary, NC.
44. Brus, L. E. (1986) Electronic wave-functions in semiconductor clusters: experiment and theory J. Phys. Chem. 90, 2555-2560
45. Gagné, F., Auclair, J., Turcotte, P., Fournier, M., Gagnon, C., Sauvé, S., and Blaise, C. (2008) Ecotoxicity of CdTe quantum dots to freshwater mussels: Impacts on immune system, oxidative stress and genotoxicity Aquatic Toxicol. 86, 333-340
46. Medintz, I. L., Uyeda, H. T., Goldman, E. R., and Mattoussi, H. (2005) Quantum dot bioconjugates for imaging, labelling and sensing Nat. Mater. 4, 435-446 (Pubitemid 40774047)
47. Clarke, S. J., Hollmann, C. A., Zhang, Z., Suffern, D., Bradforth, S. E., and Dimitrijevic, N. M. 2006, Photophysics of dopamine-modified quantum dots and effects on biological systems Nat. Mater. 5, 409-417
48. Hsieh, S. C., Wang, F. F., Hung, S. C., Chen, Y., and Wang, Y. J. (2006) The internalized CdSe/ZnS quantum dots impair the chondrogenesis of bone marrow mesenchymal stem cells J. Biomed. Mater. Res., Part B 79, 95-101 (Pubitemid 44477479)
49. Singh, N., Manshian, B., Jenkins, G. J., Griffiths, S. M., Williams, P. M., Maffeis, T. G., Wright, C. J., and Doak, S. H. (2009) NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials Biomaterials 30, 3891-914
50. Chen, F. Q. and Gerion, D. (2004) Fluorescent CdSe/ZnS nanocrystal-peptide conjugates for long-term, nontoxic imaging and nuclear targeting in living cells Nano Lett. 4, 1827-1832
51. Shiohara, A., Hoshino, A., Hanaki, K., Suzuki, K., and Yamamoto, K. (2004) On the cyto-toxicity caused by quantum dots Microbiol. Immunol. 48, 669-675 (Pubitemid 39264940)
52. Hardman, R. (2006) A toxicologic review of quantum dots: toxicity depends on physicochemical and environmental factors Environ. Health Perspect. 114, 165-172 (Pubitemid 43193634)
53. Akerman, M. E., Chan, W. C. W., Laakkonen, P., Bhatia, S. N., and Ruoslahti, E. (2002) Nanocrystal targeting in vivo Proc. Natl. Acad. Sci. U.S.A. 99, 12617-12621
54. He, Y. T., Wan, J., and Tokunga, T. (2008) Kinetic stability of hematite nanoparticles: the effect of particle J. Nanopart. Res. 10, 321-332 (Pubitemid 350301187)
55. Powers, K. W., Brown, S. C., Krishna, V. B., Wasdo, S. C., Moudgil, B. M., and Roberts, S. M. (2006) Research strategies for safety evaluation of nanomaterials. Part VI. Characterization of nanoscale particles for toxicological evaluation Toxicol. Sci. 90, 296-303
56. Fischer, H. C. and Chan, W. C. W. (2007) Nanotoxicity: the growing need for in vivo study Curr. Opin. Biotechnol. 18, 565-571
57. Aillon, K. L., Xie, Y., El-Gendy, N., Berkland, C. J., and Laird Forrest, M. (2009) Effects of nanomaterial physicochemical properties on in vivo toxicity Adv. Drug Delivery Rev. 61, 457-466
58. De Boeck, M., Lombaert, N., De Backer, S., Finsy, R., Lison, D. M., and Kirsch-Volders, M. (2003) In vitro genotoxic effects of different combinations of cobalt and metallic carbide particles Mutagenesis 18, 177-186 (Pubitemid 36336535)
59. De Boeck, M., Kirsch-Volders, M., and Lison, D. (2003) Cobalt and antimony: genotoxicity and carcinogenicity Mutat. Res. 533, 135-152 (Pubitemid 37487865)
60. Ponti, J., Sabbioni, E., Munaro, B., Broggi, F., Marmorato, P., Franchini, F., Colognato, R., and Rossi, F. (2009) Genotoxicity and morphological transformation induced by cobalt nanoparticles and cobalt chloride: an in vitro study in Balb/3T3 mouse fibroblasts Mutagenesis 24, 439-445
61. Colognato, R., Bonelli, A., Ponti, J., Farina, M., Bergamaschi, E., Sabbioni, E., and Migliore, L. (2008) Comparative genotoxicity of cobalt nanoparticles and ions on human peripheral leukocytes in vitro Mutagenesis 23, 1-6
62. Oberdörster, G., Maynard, A., and Donaldson, K. 2005, A report from the ILSI Research Foundation/Risk Science Institute National Toxicity Screening Working Group. Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy Part. Fibre Toxicol. 6, 2-8
63. Limbach, L. K., Wick, P., Manser, P., Grass, R. N., Bruinink, A., and Stark, W. J.n (2007) Exposure of engineered nanoparticles to human lung epithelial cells: influence of chemical composition and catalytic activity on oxidative stress Environ. Sci. Technol. 41, 3791-3792
64. Lison, D., De Boeck, M., Verougstraete, V., and Kirsch-Volders, M. (2001) Update on the genotoxicity and carcinogenicity of cobalt compounds Occup. Environ. Med. 58, 619-625 (Pubitemid 32881039)
65. 2 in the presence of chelators in relation to DNA damage and 2′-deoxyguanosine hydroxylation J. Toxicol. Environ. Health 47, 61-75
66. Zou, W., Yan, M., Xu, W., Huo, H., Sun, L., Zheng, Z., and Liu, Z. (2001) Cobalt chloride induces PC12 cells apoptosis through reactive oxygen species and accompanied by AP-1 activation J. Neurosci. Res. 64, 646-653 (Pubitemid 32520687)
67. Foley, S., Crowley, C., Smaihi, M., Bonfils, C., Erlanger, B. F., Seta, P., and Larroque, C. (2002) Cellular localisation of a water-soluble fullerene derivative Biochem. Biophys. Res. Commun. 294, 116-119 (Pubitemid 34687223)
68. Li, N., Sioutas, C., and Cho, A 2003, Ultrafine particulate pollutants induce oxidative stress and mitochondrial damage Environ. Health Perspect. 111, 455-460 (Pubitemid 36546522)
69. Savic, R., Luo, L., Eisenberg, A., and Maysinger, D. (2003) Micellar nanocontainers distribute to defined cytoplasmic organelles Science 300, 615-618 (Pubitemid 36520581)
70. Yang, R. S., Chang, L. W., Wu, J. P., Tsai, M. H., Wang, H. J., Kuo, Y. C., Yeh, T. K., Yang, C. S., and Lin, P. (2007) Persistent tissue kinetics and redistribution of nanoparticles, quantum dot 705, in mice: ICP-MS quantitative assessment Environ. Health Perspect. 115, 1339-1343 (Pubitemid 47471259)
71. Zhang, Y., Chen, W., Zhang, J., Liu, J., Chen, G., and Pope, C. (2007) In vitro and in vivo toxicity of CdTe nanoparticles J. Nanosci. Nanotechnol. 7, 497-503
72. Hauck, T. S., Anderson, R. E., Fischer, H. C., Newbigging, S., and Chan, W. C. (2010) In vivo quantum-dot toxicity assessment Small 6, 138-144