GDNF modifies reactive astrogliosis allowing robust axonal regeneration through Schwann cell-seeded guidance channels after spinal cord injury

Experimental Neurology

Volumn 229, Issue 2, 2011, Pages 238-250

  Deng, Ling Xiao ^a,b   Hu, Jianguo ^a,b   Liu, Naikui ^a,b   Wang, Xiaofei ^a,b   Smith, George M ^c   Wen, Xuejun ^d   Xu, Xiao Ming ^a,b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b University of Louisville School of Medicine   (United States)

^c UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

^d MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Axonal regeneration; GDNF; Reactive astrocytes; Schwann cells; Spinal cord injury; Transplantation

Indexed keywords

GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; PROTEOCHONDROITIN SULFATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; ASTROCYTE HYPERTROPHY; ASTROCYTOSIS; CELL ADHESION; CELL DAMAGE; CELL ELONGATION; CELL MIGRATION; CELL TYPE; CONTROLLED STUDY; FEMALE; HOST CELL; HYPERTROPHY; IN VITRO STUDY; IN VIVO STUDY; NERVE FIBER REGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS INHIBITION; RAT; SCHWANN CELL; SPINAL CORD HEMISECTION; SPINAL CORD INJURY; THORACIC SPINAL CORD;

ANALYSIS OF VARIANCE; ANIMALS; ASTROCYTES; AXONS; BLOTTING, WESTERN; CELL MOVEMENT; COCULTURE TECHNIQUES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GLIOSIS; IMMUNOHISTOCHEMISTRY; NERVE REGENERATION; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SCHWANN CELLS; SPINAL CORD INJURIES; WOUND HEALING;

EID: 79956109364     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.02.001     Document Type: Article

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