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Volumn 57, Issue 11, 2009, Pages 1178-1191

GDNF-enhanced axonal regeneration and myelination following spinal cord injury is mediated by primary effects on neurons

Author keywords

Axon; GDNF; Myelination; Regeneration; Schwann cell; Spinal cord injury

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; NERVE CELL ADHESION MOLECULE; NERVE CELL ADHESION MOLECULE L1; NERVE GROWTH FACTOR; NEUROTROPHIN; NEUROTROPHIN 3;

EID: 69649084348     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20840     Document Type: Article
Times cited : (141)

References (55)
  • 1
    • 0025880071 scopus 로고
    • Detection of brain-derived neurotrophic factor-like activity in fibroblasts and Schwann cells: Inhibition by antibodies to NGF
    • Acheson A, Barker PA, Alderson RF, Miller FD, Murphy RA. 1991. Detection of brain-derived neurotrophic factor-like activity in fibroblasts and Schwann cells: Inhibition by antibodies to NGF. Neuron 7:265-275.
    • (1991) Neuron , vol.7 , pp. 265-275
    • Acheson, A.1    Barker, P.A.2    Alderson, R.F.3    Miller, F.D.4    Murphy, R.A.5
  • 2
    • 0017177655 scopus 로고
    • Potential of Schwann cells from unmyelinated nerves to produce myelin: A quantitative ultrastructural and radiographic study
    • Aguayo AJ, Charron L, Bray GM. 1976. Potential of Schwann cells from unmyelinated nerves to produce myelin: A quantitative ultrastructural and radiographic study. J Neurocytol 5:565-573.
    • (1976) J Neurocytol , vol.5 , pp. 565-573
    • Aguayo, A.J.1    Charron, L.2    Bray, G.M.3
  • 3
    • 0030983548 scopus 로고    scopus 로고
    • Baloh RH, Tansey MG, Golden JP, Creedon DJ, Heuckeroth RO, Keck CL, Zimonjic DB, Popescu NC, Johnson EM Jr, Milbrandt J. 1997. TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. Neuron 18:793-802.
    • Baloh RH, Tansey MG, Golden JP, Creedon DJ, Heuckeroth RO, Keck CL, Zimonjic DB, Popescu NC, Johnson EM Jr, Milbrandt J. 1997. TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. Neuron 18:793-802.
  • 4
    • 0035122596 scopus 로고    scopus 로고
    • Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels
    • Bamber NI, Li H, Lu X, Oudega M, Aebischer P, Xu XM. 2001. Neurotrophins BDNF and NT-3 promote axonal re-entry into the distal host spinal cord through Schwann cell-seeded mini-channels. Eur J Neurosci 13:257-268.
    • (2001) Eur J Neurosci , vol.13 , pp. 257-268
    • Bamber, N.I.1    Li, H.2    Lu, X.3    Oudega, M.4    Aebischer, P.5    Xu, X.M.6
  • 5
    • 0023784077 scopus 로고
    • Identification of the major proteins that promote neuronal process outgrowth on Schwann cells in vitro
    • Bixby JL, Lilien J, Reichardt LF. 1988. Identification of the major proteins that promote neuronal process outgrowth on Schwann cells in vitro. J Cell Biol 107:353-361.
    • (1988) J Cell Biol , vol.107 , pp. 353-361
    • Bixby, J.L.1    Lilien, J.2    Reichardt, L.F.3
  • 6
    • 0141448981 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor sustain the axonal regeneration of chronically axotomized motoneurons in vivo
    • Boyd JG, Gordon T. 2003. Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor sustain the axonal regeneration of chronically axotomized motoneurons in vivo. Exp Neurol 183:610-619.
    • (2003) Exp Neurol , vol.183 , pp. 610-619
    • Boyd, J.G.1    Gordon, T.2
  • 7
    • 0035369277 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor enhances axonal regeneration following sciatic nerve transection in adult rats
    • Chen ZY, Chai YF, Cao L, Lu CL, He C. 2001. Glial cell line-derived neurotrophic factor enhances axonal regeneration following sciatic nerve transection in adult rats. Brain Res 902:272-276.
    • (2001) Brain Res , vol.902 , pp. 272-276
    • Chen, Z.Y.1    Chai, Y.F.2    Cao, L.3    Lu, C.L.4    He, C.5
  • 8
    • 0344423815 scopus 로고    scopus 로고
    • Distinct structural elements in GDNF mediate binding to GFRalpha1 and activation of the GFRalpha1-c-Ret receptor complex
    • Eketjall S, Fainzilber M, Murray-Rust J, Ibanez CF. 1999. Distinct structural elements in GDNF mediate binding to GFRalpha1 and activation of the GFRalpha1-c-Ret receptor complex. EMBO J 18: 5901-5910.
    • (1999) EMBO J , vol.18 , pp. 5901-5910
    • Eketjall, S.1    Fainzilber, M.2    Murray-Rust, J.3    Ibanez, C.F.4
  • 10
    • 0023575754 scopus 로고
    • Differentiation of axon-related Schwann cells in vitro. I. Ascorbic acid regulates basal lamina assembly and myelin formation
    • Eldridge CF, Bunge MB, Bunge RP, Wood PM. 1987. Differentiation of axon-related Schwann cells in vitro. I. Ascorbic acid regulates basal lamina assembly and myelin formation. J Cell Biol 105:1023-1034.
    • (1987) J Cell Biol , vol.105 , pp. 1023-1034
    • Eldridge, C.F.1    Bunge, M.B.2    Bunge, R.P.3    Wood, P.M.4
  • 11
    • 0020042516 scopus 로고
    • How are sheath dimensions affected by axon caliber and internode length?
    • Friede RL, Bischhausen R. 1982. How are sheath dimensions affected by axon caliber and internode length? Brain Res 235:335-350.
    • (1982) Brain Res , vol.235 , pp. 335-350
    • Friede, R.L.1    Bischhausen, R.2
  • 12
    • 0027749098 scopus 로고
    • The use of Schwann cell transplantation to foster central nervous system repair
    • Guenard V, Xu X, Bunge MB. 1993. The use of Schwann cell transplantation to foster central nervous system repair. Sem Neurosci 5:401-411.
    • (1993) Sem Neurosci , vol.5 , pp. 401-411
    • Guenard, V.1    Xu, X.2    Bunge, M.B.3
  • 13
    • 0023256354 scopus 로고
    • Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection
    • Heumann R, Korsching S, Bandtlow C, Thoenen H. 1987. Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection. J Cell Biol 104:1623-1631.
    • (1987) J Cell Biol , vol.104 , pp. 1623-1631
    • Heumann, R.1    Korsching, S.2    Bandtlow, C.3    Thoenen, H.4
  • 15
    • 0036144945 scopus 로고    scopus 로고
    • A decline in glial cell-line-derived neurotrophic factor expression is associated with impaired regeneration after long-term Schwann cell denervation
    • Hoke A, Gordon T, Zochodne DW, Sulaiman OA. 2002. A decline in glial cell-line-derived neurotrophic factor expression is associated with impaired regeneration after long-term Schwann cell denervation. Exp Neurol 173:77-85.
    • (2002) Exp Neurol , vol.173 , pp. 77-85
    • Hoke, A.1    Gordon, T.2    Zochodne, D.W.3    Sulaiman, O.A.4
  • 16
    • 0141560588 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor-enriched bridging transplants promote propriospinal axonal regeneration and enhance myelination after spinal cord injury
    • Iannotti C, Li H, Yan P, Lu X, Wirthlin L, Xu X-M. 2003. Glial cell line-derived neurotrophic factor-enriched bridging transplants promote propriospinal axonal regeneration and enhance myelination after spinal cord injury. Exp Neurol 183:379-393.
    • (2003) Exp Neurol , vol.183 , pp. 379-393
    • Iannotti, C.1    Li, H.2    Yan, P.3    Lu, X.4    Wirthlin, L.5    Xu, X.-M.6
  • 17
    • 24944520789 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor-induced signaling in Schwann cells
    • Iwase T, Jung CG, Bae H, Zhang M, Soliven B. 2005. Glial cell line-derived neurotrophic factor-induced signaling in Schwann cells. J Neurochem 94:1488-1499.
    • (2005) J Neurochem , vol.94 , pp. 1488-1499
    • Iwase, T.1    Jung, C.G.2    Bae, H.3    Zhang, M.4    Soliven, B.5
  • 19
    • 0001081109 scopus 로고    scopus 로고
    • Tissue culture methods for the study of myelination
    • Banker GA, Goslin K, editors, Boston, Massachusetts: MIT. pp
    • Kleitman N, Wood PM, Bunge RP. 1998. Tissue culture methods for the study of myelination. In: Banker GA, Goslin K, editors. Culturing nerve cells. Boston, Massachusetts: MIT. pp 545-594.
    • (1998) Culturing nerve cells , pp. 545-594
    • Kleitman, N.1    Wood, P.M.2    Bunge, R.P.3
  • 20
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons
    • Lin L-FH, Doherty DH, Lile JD, Bektesh S, Collins F. 1993. GDNF: A glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260:1130-1132.
    • (1993) Science , vol.260 , pp. 1130-1132
    • Lin, L.-F.H.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 21
    • 0033562848 scopus 로고    scopus 로고
    • Developing Schwann cells acquire the ability to survive without axons by establishing an autocrine circuit involving insulin-like growth factor, neurotrophin-3 and platelet-derived growth factor-BB
    • Meier C, Parmantier E, Brennan A, Mirsky R, Jessen KR. 1999. Developing Schwann cells acquire the ability to survive without axons by establishing an autocrine circuit involving insulin-like growth factor, neurotrophin-3 and platelet-derived growth factor-BB. J Neurosci 19:3847-3859.
    • (1999) J Neurosci , vol.19 , pp. 3847-3859
    • Meier, C.1    Parmantier, E.2    Brennan, A.3    Mirsky, R.4    Jessen, K.R.5
  • 23
    • 0032896064 scopus 로고    scopus 로고
    • The neurobiology of Schwann cells
    • Mirsky R, Jessen KR. 1999. The neurobiology of Schwann cells. Brain Pathol 9:293-311.
    • (1999) Brain Pathol , vol.9 , pp. 293-311
    • Mirsky, R.1    Jessen, K.R.2
  • 26
    • 0025939419 scopus 로고
    • Isolation and functional characterization of Schwann cells derived from adult peripheral nerve
    • Morrissey TK, Kleitman N, Bunge RP. 1991. Isolation and functional characterization of Schwann cells derived from adult peripheral nerve. J Neurosci 11:2433-2442.
    • (1991) J Neurosci , vol.11 , pp. 2433-2442
    • Morrissey, T.K.1    Kleitman, N.2    Bunge, R.P.3
  • 27
    • 0031001034 scopus 로고    scopus 로고
    • Effects of GDNF on axotomized sensory and motor neurons in adult rats
    • Munson JB, McMahon SB. 1997. Effects of GDNF on axotomized sensory and motor neurons in adult rats. Eur J Neurosci 9:1126-1129.
    • (1997) Eur J Neurosci , vol.9 , pp. 1126-1129
    • Munson, J.B.1    McMahon, S.B.2
  • 28
    • 0027207079 scopus 로고
    • Distribution of fibroblast growth factor in cultured dorsal root ganglion neurons and Schwann cells. II. Redistribution after neural injury
    • Neuberger TJ, De Vries GH. 1993. Distribution of fibroblast growth factor in cultured dorsal root ganglion neurons and Schwann cells. II. Redistribution after neural injury J Neurocytol 22:449-460.
    • (1993) J Neurocytol , vol.22 , pp. 449-460
    • Neuberger, T.J.1    De Vries, G.H.2
  • 29
    • 0027931132 scopus 로고
    • Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: Influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber
    • Nixon RA, Paskevich PA, Sihag RK, Thayer CY. 1994. Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: Influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber. J Cell Biol 126:1031-1046.
    • (1994) J Cell Biol , vol.126 , pp. 1031-1046
    • Nixon, R.A.1    Paskevich, P.A.2    Sihag, R.K.3    Thayer, C.Y.4
  • 31
    • 33646560612 scopus 로고    scopus 로고
    • Schwann cell transplantation for repair of the adult spinal cord
    • Oudega M, Xu XM. 2006. Schwann cell transplantation for repair of the adult spinal cord. J Neurotrauma 23(3-4):453-467.
    • (2006) J Neurotrauma , vol.23 , Issue.3-4 , pp. 453-467
    • Oudega, M.1    Xu, X.M.2
  • 32
    • 0038488948 scopus 로고    scopus 로고
    • The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands
    • Paratcha G, Ledda F, Ibanez CF. 2003. The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands. Cell 113:867-879.
    • (2003) Cell , vol.113 , pp. 867-879
    • Paratcha, G.1    Ledda, F.2    Ibanez, C.F.3
  • 33
    • 0037101609 scopus 로고    scopus 로고
    • Purified adult ensheathing glia fail to myelinate axons under culture conditions that enable Schwann cells to form myelin
    • Plant GW, Currier PF, Cuervo EP, Bates ML, Pressman Y, Bunge MB, Wood PM. 2002. Purified adult ensheathing glia fail to myelinate axons under culture conditions that enable Schwann cells to form myelin. J Neurosci 22:6083-6091.
    • (2002) J Neurosci , vol.22 , pp. 6083-6091
    • Plant, G.W.1    Currier, P.F.2    Cuervo, E.P.3    Bates, M.L.4    Pressman, Y.5    Bunge, M.B.6    Wood, P.M.7
  • 35
    • 0036703612 scopus 로고    scopus 로고
    • Schwann cell but not olfactory ensheathing glia transplants improve hindlimb locomotor performance in the moderately contused adult rat thoracic spinal cord
    • Takami T, Oudega M, Bates ML, Wood PM, Kleitman N, Bunge MB. 2002. Schwann cell but not olfactory ensheathing glia transplants improve hindlimb locomotor performance in the moderately contused adult rat thoracic spinal cord. J Neurosci 22:6670-6681.
    • (2002) J Neurosci , vol.22 , pp. 6670-6681
    • Takami, T.1    Oudega, M.2    Bates, M.L.3    Wood, P.M.4    Kleitman, N.5    Bunge, M.B.6
  • 36
    • 34447620322 scopus 로고    scopus 로고
    • Sensory afferents regenerated into dorsal columns after spinal cord injury remain in a chronic pathophysiological state
    • Tan AM, Petruska JC, Mendell LM, Levine JM. 2007. Sensory afferents regenerated into dorsal columns after spinal cord injury remain in a chronic pathophysiological state. Exp Neurol 206:257-268.
    • (2007) Exp Neurol , vol.206 , pp. 257-268
    • Tan, A.M.1    Petruska, J.C.2    Mendell, L.M.3    Levine, J.M.4
  • 37
    • 33845875170 scopus 로고    scopus 로고
    • PARsing the events of myelination
    • Taveggia C, Salzer JL. 2007. PARsing the events of myelination. Nat Neurosci 10:17-18.
    • (2007) Nat Neurosci , vol.10 , pp. 17-18
    • Taveggia, C.1    Salzer, J.L.2
  • 38
    • 0034893130 scopus 로고    scopus 로고
    • Soluble forms of NCAM and F3 neuronal cell adhesion molecules promote Schwann cell migration: Identification of protein tyrosine phosphatases zeta/beta as the putative F3 receptors on Schwann cells
    • Thomaidou D, Coquillat D, Meintanis S, Noda M, Rougon G, Matsas R. 2001. Soluble forms of NCAM and F3 neuronal cell adhesion molecules promote Schwann cell migration: Identification of protein tyrosine phosphatases zeta/beta as the putative F3 receptors on Schwann cells. J Neurochem 78:767-778.
    • (2001) J Neurochem , vol.78 , pp. 767-778
    • Thomaidou, D.1    Coquillat, D.2    Meintanis, S.3    Noda, M.4    Rougon, G.5    Matsas, R.6
  • 41
    • 0030915959 scopus 로고    scopus 로고
    • Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS
    • Trupp M, Belluardo N, Funakoshi H, Ibanez F. 1997. Complementary and overlapping expression of glial cell line-derived neurotrophic factor (GDNF), c-ret proto-oncogene, and GDNF receptor-alpha indicates multiple mechanisms of trophic actions in the adult rat CNS. J Neurosci 17:3554-3567.
    • (1997) J Neurosci , vol.17 , pp. 3554-3567
    • Trupp, M.1    Belluardo, N.2    Funakoshi, H.3    Ibanez, F.4
  • 42
    • 0031805128 scopus 로고    scopus 로고
    • Multiple GPI-anchored receptors control GDNF-dependent and independent activation of the c-Ret receptor tyrosine kinase
    • Trupp M, Raynoscheck C, Belluardo N, Ibanez CF. 1998. Multiple GPI-anchored receptors control GDNF-dependent and independent activation of the c-Ret receptor tyrosine kinase. Mol Cel Neurosci 11:47-63.
    • (1998) Mol Cel Neurosci , vol.11 , pp. 47-63
    • Trupp, M.1    Raynoscheck, C.2    Belluardo, N.3    Ibanez, C.F.4
  • 43
    • 0033597817 scopus 로고    scopus 로고
    • Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells
    • Trupp M, Scott R, Whittemore SR, Ibanez CF. 1999. Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells. J Biol Chem 274:20885-20894.
    • (1999) J Biol Chem , vol.274 , pp. 20885-20894
    • Trupp, M.1    Scott, R.2    Whittemore, S.R.3    Ibanez, C.F.4
  • 44
    • 0024465771 scopus 로고
    • Target size regulates caliber and myelination of sympathetic axons
    • Voyvodic JT. 1989. Target size regulates caliber and myelination of sympathetic axons. Nature 342:430-433.
    • (1989) Nature , vol.342 , pp. 430-433
    • Voyvodic, J.T.1
  • 45
    • 0017121995 scopus 로고
    • Studies on the control of myelinogenesis. II. Evidence for neuronal regulation of myelin production
    • Weinberg HJ, Spencer PS. 1976. Studies on the control of myelinogenesis. II. Evidence for neuronal regulation of myelin production. Brain Res 113:363-378.
    • (1976) Brain Res , vol.113 , pp. 363-378
    • Weinberg, H.J.1    Spencer, P.S.2
  • 46
    • 0032786795 scopus 로고    scopus 로고
    • The role of Schwann cells in neural regeneration
    • Weinstein DE. 1999. The role of Schwann cells in neural regeneration. Neuroscientist 5:208-216.
    • (1999) Neuroscientist , vol.5 , pp. 208-216
    • Weinstein, D.E.1
  • 47
    • 0035873540 scopus 로고    scopus 로고
    • Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid
    • Widenfalk J, Lundstromer K, Jubran M, Brene S, Olson L. 2001. Neurotrophic factors and receptors in the immature and adult spinal cord after mechanical injury or kainic acid. J Neurosci 21:3457-3475.
    • (2001) J Neurosci , vol.21 , pp. 3457-3475
    • Widenfalk, J.1    Lundstromer, K.2    Jubran, M.3    Brene, S.4    Olson, L.5
  • 48
    • 0021844853 scopus 로고
    • Myelination determines the caliber of dorsal root ganglion neurons in culture
    • Windebank AJ, Wood P, Bunge RP, Dyck PJ. 1985. Myelination determines the caliber of dorsal root ganglion neurons in culture. J Neurosci 5:1563-1569.
    • (1985) J Neurosci , vol.5 , pp. 1563-1569
    • Windebank, A.J.1    Wood, P.2    Bunge, R.P.3    Dyck, P.J.4
  • 49
    • 0025513853 scopus 로고
    • Inhibition of Schwann cell myelination in vitro by antibody to the L1 adhesion molecule
    • Wood PM, Schachner M, Bunge RP. 1990. Inhibition of Schwann cell myelination in vitro by antibody to the L1 adhesion molecule. J Neurosci 10:3635-3645.
    • (1990) J Neurosci , vol.10 , pp. 3635-3645
    • Wood, P.M.1    Schachner, M.2    Bunge, R.P.3
  • 50
    • 0030989043 scopus 로고    scopus 로고
    • Bridging Schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cord
    • Xu XM, Chen A, Guenard V, Kleitman N, Bunge MB. 1997. Bridging Schwann cell transplants promote axonal regeneration from both the rostral and caudal stumps of transected adult rat spinal cord. J Neurocytol 26:1-16.
    • (1997) J Neurocytol , vol.26 , pp. 1-16
    • Xu, X.M.1    Chen, A.2    Guenard, V.3    Kleitman, N.4    Bunge, M.B.5
  • 51
    • 0028874907 scopus 로고
    • A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord
    • Xu XM, Guenard V, Kleitman N, Aebischer P, Bunge MB. 1995a. A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord. Exp Neurol 134:261-272.
    • (1995) Exp Neurol , vol.134 , pp. 261-272
    • Xu, X.M.1    Guenard, V.2    Kleitman, N.3    Aebischer, P.4    Bunge, M.B.5
  • 52
    • 0028870347 scopus 로고
    • Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord
    • Xu XM, Guenard V, Kleitman N, Bunge MB. 1995b. Axonal regeneration into Schwann cell-seeded guidance channels grafted into transected adult rat spinal cord. J Comp Neurol 351:145-160.
    • (1995) J Comp Neurol , vol.351 , pp. 145-160
    • Xu, X.M.1    Guenard, V.2    Kleitman, N.3    Bunge, M.B.4
  • 53
    • 0032957573 scopus 로고    scopus 로고
    • Regrowth of axons into the distal spinal cord through a Schwann-cell-seeded mini-channel implanted into hemisected adult rat spinal cord
    • Xu XM, Zhang SX, Li H, Aebischer P, Bunge MB. 1999. Regrowth of axons into the distal spinal cord through a Schwann-cell-seeded mini-channel implanted into hemisected adult rat spinal cord. Eur J Neurosci 11:1723-1740.
    • (1999) Eur J Neurosci , vol.11 , pp. 1723-1740
    • Xu, X.M.1    Zhang, S.X.2    Li, H.3    Aebischer, P.4    Bunge, M.B.5
  • 54
    • 0028854836 scopus 로고
    • In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
    • Yan Q, Matheson C, Lopez OT. 1995. In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 373:341-344.
    • (1995) Nature , vol.373 , pp. 341-344
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3
  • 55
    • 0032521342 scopus 로고    scopus 로고
    • Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons
    • Yin X, Crawford TO, Griffin JW, Tu P, Lee VM, Li C, Roder J, Trapp BD. 1998. Myelin-associated glycoprotein is a myelin signal that modulates the caliber of myelinated axons. J Neurosci 18:1953-1962.
    • (1998) J Neurosci , vol.18 , pp. 1953-1962
    • Yin, X.1    Crawford, T.O.2    Griffin, J.W.3    Tu, P.4    Lee, V.M.5    Li, C.6    Roder, J.7    Trapp, B.D.8


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