A conserved amphipathic helix in the N-terminal regulatory region of the papillomavirus E1 helicase is required for efficient viral DNA replication

Journal of Virology

Volumn 85, Issue 11, 2011, Pages 5287-5300

  Morin, Geneviève ^a,b   Fradet Turcotte, Amélie ^a,b   di Lello, Paola ^b,c   Bergeron Labrecque, Fanny ^a,b   Omichinski, James G ^b   Archambault, Jacques ^a,b  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c HOFFMANN LA ROCHE INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNGAL PROTEIN; HELICASE; HUMAN PAPILLOMAVIRUS E1 HELICASE; HUMAN PAPILLOMAVIRUS E2 HELICASE; PROTEIN P53; PROTEIN P62; PROTEIN TFB1; PROTEIN VP16; PROTEIN VP16C; TRANSCRIPTION FACTOR IIH; UNCLASSIFIED DRUG; VIRUS DNA;

AMINO TERMINAL SEQUENCE; AMPHIPATHIC ALPHA HELIX; ARTICLE; BINDING AFFINITY; CANCER CELL CULTURE; COMPLEX FORMATION; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVITY; ENZYME ANALYSIS; FEMALE; GENE DELETION; GENE MUTATION; GENETIC CONSERVATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; ISOTHERMAL TITRATION CALORIMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; TRANSACTIVATION; TRANSCRIPTION REGULATION; UTERINE CERVIX CARCINOMA; WART VIRUS;

CALORIMETRY; DNA HELICASES; DNA MUTATIONAL ANALYSIS; DNA, VIRAL; EPITHELIAL CELLS; HUMANS; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PAPILLOMAVIRIDAE; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; SACCHAROMYCES CEREVISIAE; SEQUENCE DELETION; SEQUENCE HOMOLOGY, AMINO ACID; TRANS-ACTIVATORS; VIRAL PROTEINS; VIRUS REPLICATION;

HUMAN PAPILLOMAVIRUS TYPES; MAMMALIA; PAPILLOMAVIRIDAE; SACCHAROMYCES; SIMPLEXVIRUS;

EID: 79956103105     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01829-10     Document Type: Article

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