메뉴 건너뛰기




Volumn 16, Issue 8, 2009, Pages 1108-1117

The α/β carboxy-terminal domains of p63 are required for skin and limb development. New insights from the Brdm2 mouse which is not a complete p63 knockout but expresses p63 γ-like proteins

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ISOPROTEIN; PROTEIN P53; PROTEIN P63; PROTEIN P63ALPHA; PROTEIN P63BETA; PROTEIN P63GAMMA; UNCLASSIFIED DRUG;

EID: 67650727439     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2009.25     Document Type: Article
Times cited : (29)

References (32)
  • 1
    • 0032161624 scopus 로고    scopus 로고
    • p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities
    • Yang A, Kaghad M, Wang Y, Gillett E, Fleming MD, Dotsch V et al. p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities. Mol Cell 1998; 2: 305-316.
    • (1998) Mol Cell , vol.2 , pp. 305-316
    • Yang, A.1    Kaghad, M.2    Wang, Y.3    Gillett, E.4    Fleming, M.D.5    Dotsch, V.6
  • 2
    • 0033594491 scopus 로고    scopus 로고
    • p63 is a p53 homologue required for limb and epidermal morphogenesis
    • Mills AA, Zheng B, Wang XJ, Vogel H, Roop DR, Bradley A. p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature 1999; 398: 708-713.
    • (1999) Nature , vol.398 , pp. 708-713
    • Mills, A.A.1    Zheng, B.2    Wang, X.J.3    Vogel, H.4    Roop, D.R.5    Bradley, A.6
  • 3
    • 0033594485 scopus 로고    scopus 로고
    • p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
    • Yang A, Schweitzer R, Sun D, Kaghad M, Walker N, Bronson RT et al. p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development. Nature 1999; 398: 714-718.
    • (1999) Nature , vol.398 , pp. 714-718
    • Yang, A.1    Schweitzer, R.2    Sun, D.3    Kaghad, M.4    Walker, N.5    Bronson, R.T.6
  • 4
    • 0033152654 scopus 로고    scopus 로고
    • A system for rapid generation of coat color-tagged knock-outs and defined chromosomal rearrangements in mice
    • Zheng B, Mills AA, Bradley A. A system for rapid generation of coat color-tagged knock-outs and defined chromosomal rearrangements in mice. Nucleic Acids Res 1999; 27: 2354-2360.
    • (1999) Nucleic Acids Res , vol.27 , pp. 2354-2360
    • Zheng, B.1    Mills, A.A.2    Bradley, A.3
  • 5
    • 1642377359 scopus 로고    scopus 로고
    • p63 and the epithelial stem cell: More than status quo?
    • McKeon F. p63 and the epithelial stem cell: More than status quo? Genes Dev 2004; 18: 465-469.
    • (2004) Genes Dev , vol.18 , pp. 465-469
    • McKeon, F.1
  • 6
    • 0942301281 scopus 로고    scopus 로고
    • p63 is the molecular switch for initiation of an epithelial stratification program
    • Koster MI, Kim S, Mills AA, DeMayo FJ, Roop DR. p63 is the molecular switch for initiation of an epithelial stratification program. Genes Dev 2004; 18: 126-131.
    • (2004) Genes Dev , vol.18 , pp. 126-131
    • Koster, M.I.1    Kim, S.2    Mills, A.A.3    DeMayo, F.J.4    Roop, D.R.5
  • 7
    • 34247511981 scopus 로고    scopus 로고
    • p63 Is essential for the proliferative potential of stem cells in stratified epithelia
    • Senoo M, Pinto F, Crum CP, McKeon F. p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell 2007; 129: 523-536.
    • (2007) Cell , vol.129 , pp. 523-536
    • Senoo, M.1    Pinto, F.2    Crum, C.P.3    McKeon, F.4
  • 8
    • 24644518052 scopus 로고    scopus 로고
    • p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo
    • Perez-Losada J, Wu D, DelRosario R, Balmain A, Mao JH. p63 and p73 do not contribute to p53-mediated lymphoma suppressor activity in vivo. Oncogene 2005; 24: 5521-5524.
    • (2005) Oncogene , vol.24 , pp. 5521-5524
    • Perez-Losada, J.1    Wu, D.2    DelRosario, R.3    Balmain, A.4    Mao, J.H.5
  • 10
    • 17444390129 scopus 로고    scopus 로고
    • Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family
    • Flores ER, Sengupta S, Miller JB, Newman JJ, Bronson R, Crowley D et al. Tumor predisposition in mice mutant for p63 and p73: Evidence for broader tumor suppressor functions for the p53 family. Cancer Cell 2005; 7: 363-373.
    • (2005) Cancer Cell , vol.7 , pp. 363-373
    • Flores, E.R.1    Sengupta, S.2    Miller, J.B.3    Newman, J.J.4    Bronson, R.5    Crowley, D.6
  • 11
    • 33846063210 scopus 로고    scopus 로고
    • DeltaNp63 plays an anti-apoptotic role in ventral bladder development
    • Cheng W, Jacobs WB, Zhang JJ, Moro A, Park JH, Kushida M et al. DeltaNp63 plays an anti-apoptotic role in ventral bladder development. Development 2006; 133: 4783-4792.
    • (2006) Development , vol.133 , pp. 4783-4792
    • Cheng, W.1    Jacobs, W.B.2    Zhang, J.J.3    Moro, A.4    Park, J.H.5    Kushida, M.6
  • 12
    • 0033603494 scopus 로고    scopus 로고
    • p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53
    • Davison TS, Vagner C, Kaghad M, Ayed A, Caput D, Arrowsmith CH. p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53. J Biol Chem 1999; 274: 18709-18714.
    • (1999) J Biol Chem , vol.274 , pp. 18709-18714
    • Davison, T.S.1    Vagner, C.2    Kaghad, M.3    Ayed, A.4    Caput, D.5    Arrowsmith, C.H.6
  • 13
    • 0030981049 scopus 로고    scopus 로고
    • A genetic approach to mapping the p53 binding site in the MDM2 protein
    • Freedman DA, Epstein CB, Roth JC, Levine AJ. A genetic approach to mapping the p53 binding site in the MDM2 protein. Mol Med 1997; 3: 248-259.
    • (1997) Mol Med , vol.3 , pp. 248-259
    • Freedman, D.A.1    Epstein, C.B.2    Roth, J.C.3    Levine, A.J.4
  • 15
    • 24344447780 scopus 로고    scopus 로고
    • p63 deficiency activates a program of cellular senescence and leads to accelerated aging
    • Keyes WM, Wu Y, Vogel H, Guo X, Lowe SW, Mills AA. p63 deficiency activates a program of cellular senescence and leads to accelerated aging. Genes Dev 2005; 19: 1986-1999.
    • (2005) Genes Dev , vol.19 , pp. 1986-1999
    • Keyes, W.M.1    Wu, Y.2    Vogel, H.3    Guo, X.4    Lowe, S.W.5    Mills, A.A.6
  • 17
    • 23144455530 scopus 로고    scopus 로고
    • Differential expression of p63 isoforms in female reproductive organs
    • Kurita T, Cunha GR, Robboy SJ, Mills AA, Medina RT. Differential expression of p63 isoforms in female reproductive organs. Mech Dev 2005; 122: 1043-1055.
    • (2005) Mech Dev , vol.122 , pp. 1043-1055
    • Kurita, T.1    Cunha, G.R.2    Robboy, S.J.3    Mills, A.A.4    Medina, R.T.5
  • 21
    • 3543110350 scopus 로고    scopus 로고
    • p63 and p73: Roles in development and tumor formation
    • Moll UM, Slade N. p63 and p73: Roles in development and tumor formation. Mol Cancer Res 2004; 2: 371-386.
    • (2004) Mol Cancer Res , vol.2 , pp. 371-386
    • Moll, U.M.1    Slade, N.2
  • 23
    • 33845545810 scopus 로고    scopus 로고
    • p63 expression pattern in foetal and neonatal gonocytes after irradiation and role in the resulting apoptosis by using p63 knockout mice
    • Petre-Lazar B, Moreno SG, Livera G, Duquenne C, Habert R, Coffigny H. p63 expression pattern in foetal and neonatal gonocytes after irradiation and role in the resulting apoptosis by using p63 knockout mice. Int J Radiat Biol 2006; 82: 771-780.
    • (2006) Int J Radiat Biol , vol.82 , pp. 771-780
    • Petre-Lazar, B.1    Moreno, S.G.2    Livera, G.3    Duquenne, C.4    Habert, R.5    Coffigny, H.6
  • 24
    • 0038458958 scopus 로고    scopus 로고
    • Distribution of p63, a novel myoepithelial marker, in fine-needle aspiration biopsies of the breast: An analysis of 82 samples
    • Reis-Filho JS, Milanezi F, Amendoeira I, Albergaria A, Schmitt FC. Distribution of p63, a novel myoepithelial marker, in fine-needle aspiration biopsies of the breast: An analysis of 82 samples. Cancer 2003; 99: 172-179.
    • (2003) Cancer , vol.99 , pp. 172-179
    • Reis-Filho, J.S.1    Milanezi, F.2    Amendoeira, I.3    Albergaria, A.4    Schmitt, F.C.5
  • 26
    • 36749071064 scopus 로고    scopus 로고
    • Boldrup L, Coates PJ, Gu X, Nylander K. DeltaNp63 isoforms regulate CD44 and keratins 4, 6, 14 and 19 in squamous cell carcinoma of head and neck. J Pathol 2007; 213: 384-391.
    • Boldrup L, Coates PJ, Gu X, Nylander K. DeltaNp63 isoforms regulate CD44 and keratins 4, 6, 14 and 19 in squamous cell carcinoma of head and neck. J Pathol 2007; 213: 384-391.
  • 28
    • 32244434160 scopus 로고    scopus 로고
    • Keyes WM, Mills AA. p63: A new link between senescence and aging. Cell Cycle 2006; 5: 260-265.
    • Keyes WM, Mills AA. p63: A new link between senescence and aging. Cell Cycle 2006; 5: 260-265.
  • 29
    • 0035679178 scopus 로고    scopus 로고
    • Roles of p63 in differentiation of Mullerian duct epithelial cells
    • Kurita T, Cunha GR. Roles of p63 in differentiation of Mullerian duct epithelial cells. Ann NY Acad Sci 2001; 948: 9-12.
    • (2001) Ann NY Acad Sci , vol.948 , pp. 9-12
    • Kurita, T.1    Cunha, G.R.2
  • 30
    • 2342438762 scopus 로고    scopus 로고
    • Roles of p63 in the diethylstilbestrol-induced cervicovaginal adenosis
    • Kurita T, Mills AA, Cunha GR. Roles of p63 in the diethylstilbestrol-induced cervicovaginal adenosis. Development 2004; 131: 1639-1649.
    • (2004) Development , vol.131 , pp. 1639-1649
    • Kurita, T.1    Mills, A.A.2    Cunha, G.R.3
  • 31
    • 37249038477 scopus 로고    scopus 로고
    • Abnormal urethra formation in mouse models of split-hand/ split-foot malformation type 1 and type 4
    • Suzuki K, Haraguchi R, Ogata T, Barbieri O, Alegria O, Vieux-Rochas M et al. Abnormal urethra formation in mouse models of split-hand/ split-foot malformation type 1 and type 4. Eur J Hum Genet 2008; 16: 36-44.
    • (2008) Eur J Hum Genet , vol.16 , pp. 36-44
    • Suzuki, K.1    Haraguchi, R.2    Ogata, T.3    Barbieri, O.4    Alegria, O.5    Vieux-Rochas, M.6
  • 32
    • 33847029172 scopus 로고    scopus 로고
    • p63, cellular senescence and tumor development
    • Guo X, Mills AA. p63, cellular senescence and tumor development. Cell Cycle 2007; 6: 305-311.
    • (2007) Cell Cycle , vol.6 , pp. 305-311
    • Guo, X.1    Mills, A.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.