Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 shfm1 locus

PLoS Genetics

Volumn 6, Issue 8, 2010, Pages

  Kouwenhoven, Evelyn N ^a   va Heeringen, Simon J ^a   Tena, Juan J ^b   Oti, Martin ^a   Dutilh, Bas E ^a   Alonso, M Eva ^c   de la Elisa, Calle Mustienes ^b   Smeenk, Leonie ^a   Rinne, Tuula ^a   Parsaulian, Lilian ^a   Bolat, Emine ^a   Jurgelenaite, Rasa ^a   Huynen, Martijn A ^a   Hoischen, Alexander ^a   Veltman, Joris A ^a   Brunner, Han G ^a   Roscioli, Tony ^a   Oates, Emily ^d   Wilson, Meredith ^d   Manzanares, Miguel ^c   José, Luis Gómez Skarmeta ^b   Stunnenberg, Hendrik G ^a   Lohrum, Marion ^a   van Bokhoven, Hans ^a,e   Zhou, Huiqing ^a   more..

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSIDAD PABLO DE OLAVIDE   (Spain)

^c CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^d CHILDREN S HOSPITAL AT WESTMEAD   (Australia)

^e RADBOUD UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; PROTEIN P63; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR DLX6; UNCLASSIFIED DRUG; CKAP4 PROTEIN, HUMAN; DLX5 PROTEIN, HUMAN; DLX6 PROTEIN, HUMAN; DNA BINDING PROTEIN; HOMEODOMAIN PROTEIN; MEMBRANE PROTEIN; PROTEASOME; SHFM1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CASE REPORT; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME 7Q; CLEFT FACE; CLEFT LIP; CONGENITAL MALFORMATION; CONGENITAL SKIN DISEASE; ECTRODACTYLY; EMBRYO; ENHANCER REGION; FEMALE; GENE DELETION; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENE TARGETING; HETEROZYGOSITY; HUMAN; HUMAN CELL; KERATINOCYTE; LIMB DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROTEIN DNA BINDING; PROTEIN EXPRESSION; ANIMAL; CELL CULTURE; CHROMOSOME 7; GENETIC ASSOCIATION; GENETICS; LIMB MALFORMATION; MALE; METABOLISM; MOLECULAR GENETICS; MOUSE; PRESCHOOL CHILD; PROTEIN BINDING; ZEBRA FISH;

ANIMALS; BASE SEQUENCE; BINDING SITES; CELLS, CULTURED; CHILD, PRESCHOOL; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOMES, HUMAN, PAIR 7; DNA-BINDING PROTEINS; ENHANCER ELEMENTS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOME-WIDE ASSOCIATION STUDY; HOMEODOMAIN PROTEINS; HUMANS; KERATINOCYTES; LIMB DEFORMITIES, CONGENITAL; MALE; MEMBRANE PROTEINS; MICE; MOLECULAR SEQUENCE DATA; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; TRANSCRIPTION FACTORS; ZEBRAFISH;

EID: 77957371805     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1001065     Document Type: Article

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