메뉴 건너뛰기




Volumn 52, Issue 6, 2011, Pages 1073-1083

A method for visualization of "omic" datasets for sphingolipid metabolism to predict potentially interesting differences

Author keywords

Cancer; Lipidomics; Pathway visualization; Transcriptomics

Indexed keywords

SPHINGOLIPID;

EID: 79956031443     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M010454     Document Type: Article
Times cited : (23)

References (84)
  • 1
    • 38549152194 scopus 로고    scopus 로고
    • Principles of bioactive lipid signalling: Lessons from sphingolipids
    • Hannun, Y. A., and L. M. Obeid. 2008. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat. Rev. Mol. Cell Biol. 9: 139-150.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 139-150
    • Hannun, Y.A.1    Obeid, L.M.2
  • 2
    • 66349124729 scopus 로고    scopus 로고
    • Sphingosine-1- Phosphate: The Swiss army knife of sphingolipid signaling
    • Maceyka, M., S. Milstien, and S. Spiegel. 2009. Sphingosine-1- phosphate: the Swiss army knife of sphingolipid signaling. J. Lipid Res. 50 (Suppl): S272-S276.
    • (2009) J. Lipid Res. , vol.50 , Issue.SUPPL.
    • Maceyka, M.1    Milstien, S.2    Spiegel, S.3
  • 3
    • 70349871692 scopus 로고    scopus 로고
    • Gangliosides in cell recognition and membrane protein regulation
    • Lopez, P. H., and R. L. Schnaar. 2009. Gangliosides in cell recognition and membrane protein regulation. Curr. Opin. Struct. Biol. 19: 549-557.
    • (2009) Curr. Opin. Struct. Biol. , vol.19 , pp. 549-557
    • Lopez, P.H.1    Schnaar, R.L.2
  • 4
    • 68349095535 scopus 로고    scopus 로고
    • Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers
    • Shaner, R. L., J. C. Allegood, H. Park, E. Wang, S. Kelly, C. A. Haynes, M. C. Sullards, and A. H. Merrill, Jr. 2009. Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers. J. Lipid Res. 50: 1692-1707.
    • (2009) J. Lipid Res. , vol.50 , pp. 1692-1707
    • Shaner, R.L.1    Allegood, J.C.2    Park, H.3    Wang, E.4    Kelly, S.5    Haynes, C.A.6    Sullards, M.C.7    Merrill Jr., A.H.8
  • 6
    • 58949097030 scopus 로고    scopus 로고
    • A review of lipidomic technologies applicable to sphingolipidomics and their relevant applications
    • Han, X., and X. Jiang. 2009. A review of lipidomic technologies applicable to sphingolipidomics and their relevant applications. Eur. J. Lipid Sci. Technol. 111: 39-52.
    • (2009) Eur. J. Lipid Sci. Technol. , vol.111 , pp. 39-52
    • Han, X.1    Jiang, X.2
  • 7
    • 45249110673 scopus 로고    scopus 로고
    • On-line nano-HPLC/ESI QTOF MS and tandem MS for separation, detection, and structural elucidation of human erythrocytes neutral glycosphingolipid mixture
    • DOI 10.1021/ac702175f
    • Kirsch, S., M. Zarei, M. Cindric, J. Muthing, L. Bindila, and J. Peter-Katalinic. 2008. On-line nano-HPLC/ESI QTOF MS and tandem MS for separation, detection, and structural elucidation of human erythrocytes neutral glycosphingolipid mixture. Anal. Chem. 80: 4711-4722. (Pubitemid 351842351)
    • (2008) Analytical Chemistry , vol.80 , Issue.12 , pp. 4711-4722
    • Kirsch, S.1    Zarei, M.2    Cindric, M.3    Muthing, J.4    Bindila, L.5    Peter-Katalinic, J.6
  • 8
    • 70349847363 scopus 로고    scopus 로고
    • Top-down glycolipidomics: Fragmentation analysis of ganglioside oligosaccharide core and ceramide moiety by chip-nanoelectrospray collision-induced dissociation MS2-MS6
    • Serb, A., C. Schiopu, C. Flangea, E. Sisu, and A. D. Zamfir. 2009. Top-down glycolipidomics: fragmentation analysis of ganglioside oligosaccharide core and ceramide moiety by chip-nanoelectrospray collision-induced dissociation MS2-MS6. J. Mass Spectrom. 44: 1434-1442.
    • (2009) J. Mass Spectrom. , vol.44 , pp. 1434-1442
    • Serb, A.1    Schiopu, C.2    Flangea, C.3    Sisu, E.4    Zamfir, A.D.5
  • 9
    • 35348871278 scopus 로고    scopus 로고
    • (Glyco)sphingolipidology: An amazing challenge and opportunity for systems biology
    • Merrill, A. H., Jr., M. D. Wang, M. Park, and M. C. Sullards. 2007. (Glyco)sphingolipidology: an amazing challenge and opportunity for systems biology. Trends Biochem. Sci. 32: 457-468.
    • (2007) Trends Biochem. Sci. , vol.32 , pp. 457-468
    • Merrill Jr., A.H.1    Wang, M.D.2    Park, M.3    Sullards, M.C.4
  • 10
    • 40849119996 scopus 로고    scopus 로고
    • Structure and function of glycosphingolipids and sphingolipids: Recollections and future trends
    • Hakomori, S. I. 2008. Structure and function of glycosphingolipids and sphingolipids: recollections and future trends. Biochim. Biophys. Acta. 1780: 325-346.
    • (2008) Biochim. Biophys. Acta. , vol.1780 , pp. 325-346
    • Hakomori, S.I.1
  • 11
    • 0036677372 scopus 로고    scopus 로고
    • Glycosylation defining cancer malignancy: New wine in an old bottle
    • Hakomori, S. 2002. Glycosylation defining cancer malignancy: new wine in an old bottle. Proc. Natl. Acad. Sci. USA. 99: 10231-10233.
    • (2002) Proc. Natl. Acad. Sci. USA. , vol.99 , pp. 10231-10233
    • Hakomori, S.1
  • 12
    • 0034963231 scopus 로고    scopus 로고
    • Tumor-associated carbohydrate antigens defining tumor malignancy: Basis for development of anti-cancer vaccines
    • Hakomori, S. 2001. Tumor-associated carbohydrate antigens defining tumor malignancy: basis for development of anti-cancer vaccines. Adv. Exp. Med. Biol. 491: 369-402. (Pubitemid 32595136)
    • (2001) Advances in Experimental Medicine and Biology , vol.491 , pp. 369-402
    • Hakomori, S.-I.1
  • 14
    • 50149118358 scopus 로고    scopus 로고
    • Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis
    • Chang, W. W., C. H. Lee, P. Lee, J. Lin, C. W. Hsu, J. T. Hung, J. J. Lin, J. C. Yu, L. E. Shao, J. Yu, et al. 2008. Expression of Globo H and SSEA3 in breast cancer stem cells and the involvement of fucosyl transferases 1 and 2 in Globo H synthesis. Proc. Natl. Acad. Sci. USA. 105: 11667-11672.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 11667-11672
    • Chang, W.W.1    Lee, C.H.2    Lee, P.3    Lin, J.4    Hsu, C.W.5    Hung, J.T.6    Lin, J.J.7    Yu, J.C.8    Shao, L.E.9    Yu, J.10
  • 15
    • 0028804517 scopus 로고
    • Circulating gangliosides of breast-cancer patients
    • Wiesner, D. A., and C. C. Sweeley. 1995. Circulating gangliosides of breast-cancer patients. Int. J. Cancer. 60: 294-299.
    • (1995) Int. J. Cancer. , vol.60 , pp. 294-299
    • Wiesner, D.A.1    Sweeley, C.C.2
  • 16
    • 0029610984 scopus 로고
    • Expression of alpha2,8-sialyltransferase (GD3 synthase) gene in human cancer cell lines: High level expression in melanomas and up-regulation in activated T lymphocytes
    • DOI 10.1007/BF00731251
    • Yamashiro, S., M. Okada, M. Haraguchi, K. Furukawa, K. O. Lloyd, and H. Shiku. 1995. Expression of alpha 2,8-sialyltransferase (GD3 synthase) gene in human cancer cell lines: high level expression in melanomas and up-regulation in activated T lymphocytes. Glycoconj. J. 12: 894-900. (Pubitemid 26022291)
    • (1995) Glycoconjugate Journal , vol.12 , Issue.6 , pp. 894-900
    • Yamashiro, S.1    Okada, M.2    Haraguchi, M.3    Furukawa, K.4    Lloyd, K.O.5    Shiku, H.6    Furukawa, K.7
  • 20
    • 41949140023 scopus 로고    scopus 로고
    • Characterization of ceramide synthase 2: Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
    • Laviad, E. L., L. Albee, I. Pankova-Kholmyansky, S. Epstein, H. Park, A. H. Merrill, Jr., and A. H. Futerman. 2008. Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J. Biol. Chem. 283: 5677-5684.
    • (2008) J. Biol. Chem. , vol.283 , pp. 5677-5684
    • Laviad, E.L.1    Albee, L.2    Pankova-Kholmyansky, I.3    Epstein, S.4    Park, H.5    Merrill Jr., A.H.6    Futerman, A.H.7
  • 21
    • 23944483995 scopus 로고    scopus 로고
    • Mammalian Lass6 and its related family members regulate synthesis of specific ceramides
    • DOI 10.1042/BJ20050291
    • Mizutani, Y., A. Kihara, and Y. Igarashi. 2005. Mammalian Lass6 and its related family members regulate synthesis of specific ceramides. Biochem. J. 390: 263-271. (Pubitemid 41192252)
    • (2005) Biochemical Journal , vol.390 , Issue.1 , pp. 263-271
    • Mizutani, Y.1    Kihara, A.2    Igarashi, Y.3
  • 22
    • 33748747214 scopus 로고    scopus 로고
    • LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity
    • DOI 10.1042/BJ20060379
    • Mizutani, Y., A. Kihara, and Y. Igarashi. 2006. LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity. Biochem. J. 398: 531-538. (Pubitemid 44453398)
    • (2006) Biochemical Journal , vol.398 , Issue.3 , pp. 531-538
    • Mizutani, Y.1    Kihara, A.2    Igarashi, Y.3
  • 23
    • 0242353271 scopus 로고    scopus 로고
    • Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors
    • Riebeling, C., J. C. Allegood, E. Wang, A. H. Merrill, Jr., and A. H. Futerman. 2003. Two mammalian longevity assurance gene (LAG1) family members, trh1 and trh4, regulate dihydroceramide synthesis using different fatty acyl-CoA donors. J. Biol. Chem. 278: 43452-43459.
    • (2003) J. Biol. Chem. , vol.278 , pp. 43452-43459
    • Riebeling, C.1    Allegood, J.C.2    Wang, E.3    Merrill Jr., A.H.4    Futerman, A.H.5
  • 24
    • 0037144554 scopus 로고    scopus 로고
    • Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro)ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells
    • Venkataraman, K., C. Riebeling, J. Bodennec, H. Riezman, J. C. Allegood, M. C. Sullards, A. H. Merrill, Jr., and A. H. Futerman. 2002. Upstream of growth and differentiation factor 1 (uog1), a mammalian homolog of the yeast longevity assurance gene 1 (LAG1), regulates N-stearoyl-sphinganine (C18-(dihydro) ceramide) synthesis in a fumonisin B1-independent manner in mammalian cells. J. Biol. Chem. 277: 35642-35649.
    • (2002) J. Biol. Chem. , vol.277 , pp. 35642-35649
    • Venkataraman, K.1    Riebeling, C.2    Bodennec, J.3    Riezman, H.4    Allegood, J.C.5    Sullards, M.C.6    Merrill Jr., A.H.7    Futerman, A.H.8
  • 25
    • 2542558105 scopus 로고    scopus 로고
    • DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine
    • DOI 10.1042/BJ20031425
    • Omae, F., M. Miyazaki, A. Enomoto, M. Suzuki, Y. Suzuki, and A. Suzuki. 2004. DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine. Biochem. J. 379: 687-695. (Pubitemid 38703653)
    • (2004) Biochemical Journal , vol.379 , Issue.3 , pp. 687-695
    • Omae, F.1    Miyazaki, M.2    Enomoto, A.3    Suzuki, M.4    Suzuki, Y.5    Suzuki, A.6
  • 31
    • 34547871639 scopus 로고    scopus 로고
    • GEOquery: A bridge between the Gene Expression Omnibus (GEO) and BioConductor
    • Sean, D., and P. S. Meltzer. 2007. GEOquery: a bridge between the Gene Expression Omnibus (GEO) and BioConductor. Bioinformatics. 23: 1846-1847.
    • (2007) Bioinformatics , vol.23 , pp. 1846-1847
    • Sean, D.1    Meltzer, P.S.2
  • 34
    • 0036226603 scopus 로고    scopus 로고
    • BLAT - The BLAST-like alignment tool
    • Kent, W. J. 2002. BLAT - the BLAST-like alignment tool. Genome Res. 12: 656-664.
    • (2002) Genome Res. , vol.12 , pp. 656-664
    • Kent, W.J.1
  • 37
    • 41449099770 scopus 로고    scopus 로고
    • Structure-specific, quantitative methods for analysis of sphingolipids by liquid chromatography-tandem mass spectrometry: "inside-out" sphingolipidomics
    • Sullards, M. C., J. C. Allegood, S. Kelly, E. Wang, C. A. Haynes, H. Park, Y. Chen, and A. H. Merrill, Jr. 2007. Structure-specific, quantitative methods for analysis of sphingolipids by liquid chromatography-tandem mass spectrometry: "inside-out" sphingolipidomics. Methods Enzymol. 432: 83-115.
    • (2007) Methods Enzymol. , vol.432 , pp. 83-115
    • Sullards, M.C.1    Allegood, J.C.2    Kelly, S.3    Wang, E.4    Haynes, C.A.5    Park, H.6    Chen, Y.7    Merrill Jr., A.H.8
  • 40
    • 2442423192 scopus 로고    scopus 로고
    • Expression Cloning of a Human cDNA Restoring Sphingomyelin Synthesis and Cell Growth in Sphingomyelin Synthase-defective Lymphoid Cells
    • DOI 10.1074/jbc.M401205200
    • Yamaoka, S., M. Miyaji, T. Kitano, H. Umehara, and T. Okazaki. 2004. Expression cloning of a human cDNA restoring sphingomyelin synthesis and cell growth in sphingomyelin synthase-defective lymphoid cells. J. Biol. Chem. 279: 18688-18693. (Pubitemid 38623292)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.18 , pp. 18688-18693
    • Yamaoka, S.1    Miyaji, M.2    Kitano, T.3    Umehara, H.4    Okazaki, T.5
  • 41
    • 70350383478 scopus 로고    scopus 로고
    • Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase
    • Ternes, P., J. F. Brouwers, J. van den Dikkenberg, and J. C. Holthuis. 2009. Sphingomyelin synthase SMS2 displays dual activity as ceramide phosphoethanolamine synthase. J. Lipid Res. 50: 2270-2277.
    • (2009) J. Lipid Res. , vol.50 , pp. 2270-2277
    • Ternes, P.1    Brouwers, J.F.2    Van Den Dikkenberg, J.3    Holthuis, J.C.4
  • 45
    • 26844446116 scopus 로고
    • Biosynthesis of nervonic acid and its homologues from carboxyl-labeled oleic acid
    • Kishimoto, Y., and N. S. Radin. 1963. Biosynthesis of nervonic acid and its homologues from carboxyl-labeled oleic acid. J. Lipid Res. 4: 444-447.
    • (1963) J. Lipid Res. , vol.4 , pp. 444-447
    • Kishimoto, Y.1    Radin, N.S.2
  • 48
    • 0031959631 scopus 로고    scopus 로고
    • Glycosphingolipid composition of MDA-MB-231 and MCF-7 human breast cancer cell lines
    • DOI 10.1023/A:1005986606010
    • Nohara, K., F. Wang, and S. Spiegel. 1998. Glycosphingolipid composition of MDA-MB-231 and MCF-7 human breast cancer cell lines. Breast Cancer Res. Treat. 48: 149-157. (Pubitemid 28156359)
    • (1998) Breast Cancer Research and Treatment , vol.48 , Issue.2 , pp. 149-157
    • Nohara, K.1    Wang, F.2    Spiegel, S.3
  • 50
    • 0020692515 scopus 로고
    • Generation of monoclonal antibodies reacting with normal and cancer cells of human breast
    • Menard, S., E. Tagliabue, S. Canevari, G. Fossati, and M. I. Colnaghi. 1983. Generation of monoclonal antibodies reacting with normal and cancer cells of human breast. Cancer Res. 43: 1295-1300.
    • (1983) Cancer Res. , vol.43 , pp. 1295-1300
    • Menard, S.1    Tagliabue, E.2    Canevari, S.3    Fossati, G.4    Colnaghi, M.I.5
  • 51
    • 77954406077 scopus 로고    scopus 로고
    • Elevation of sulfatides in ovarian cancer: An integrated transcriptomic and lipidomic analysis including tissue-imaging mass spectrometry
    • Liu, Y., Y. Chen, A. Momin, R. Shaner, E. Wang, N. J. Bowen, L. V. Matyunina, L. D. Walker, J. F. McDonald, M. C. Sullards, et al. 2010. Elevation of sulfatides in ovarian cancer: an integrated transcriptomic and lipidomic analysis including tissue-imaging mass spectrometry. Mol. Cancer. 9: 186.
    • (2010) Mol. Cancer. , vol.9 , pp. 186
    • Liu, Y.1    Chen, Y.2    Momin, A.3    Shaner, R.4    Wang, E.5    Bowen, N.J.6    Matyunina, L.V.7    Walker, L.D.8    McDonald, J.F.9    Sullards, M.C.10
  • 52
    • 33846021289 scopus 로고    scopus 로고
    • Cloning and initial characterization of a new subunit for mammalian serine-palmitoyltransferase
    • DOI 10.1074/jbc.M608066200
    • Hornemann, T., S. Richard, M. F. Rutti, Y. Wei, and A. von Eckardstein. 2006. Cloning and initial characterization of a new subunit for mammalian serine-palmitoyltransferase. J. Biol. Chem. 281: 37275-37281. (Pubitemid 46042031)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.49 , pp. 37275-37281
    • Hornemann, T.1    Richard, S.2    Rutti, M.F.3    Wei, Y.4    Von Eckardstein, A.5
  • 53
    • 10344248907 scopus 로고    scopus 로고
    • FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane
    • DOI 10.1074/jbc.M405915200
    • Kihara, A., and Y. Igarashi. 2004. FVT-1 is a mammalian 3-ketodihydrosphingosine reductase with an active site that faces the cytosolic side of the endoplasmic reticulum membrane. J. Biol. Chem. 279: 49243-49250. (Pubitemid 39625809)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.47 , pp. 49243-49250
    • Kihara, A.1    Igarashi, Y.2
  • 55
    • 0034721549 scopus 로고    scopus 로고
    • Human sphingosine-1-phosphate lyase: CDNA cloning, functional expression studies and mapping to chromosome 10q22(1)
    • Van Veldhoven, P. P., S. Gijsbers, G. P. Mannaerts, J. R. Vermeesch, and V. Brys. 2000. Human sphingosine-1-phosphate lyase: cDNA cloning, functional expression studies and mapping to chromosome 10q22(1). Biochim. Biophys. Acta. 1487: 128-134.
    • (2000) Biochim. Biophys. Acta , vol.1487 , pp. 128-134
    • Van Veldhoven, P.P.1    Gijsbers, S.2    Mannaerts, G.P.3    Vermeesch, J.R.4    Brys, V.5
  • 56
    • 0043234296 scopus 로고    scopus 로고
    • Cloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: An enzyme that preferentially regulates metabolism of very long chain ceramides
    • Mao, C., R. Xu, Z. M. Szulc, J. Bielawski, K. P. Becker, A. Bielawska, S. H. Galadari, W. Hu, and L. M. Obeid. 2003. Cloning and characterization of a mouse endoplasmic reticulum alkaline ceramidase: an enzyme that preferentially regulates metabolism of very long chain ceramides. J. Biol. Chem. 278: 31184-31191.
    • (2003) J. Biol. Chem. , vol.278 , pp. 31184-31191
    • Mao, C.1    Xu, R.2    Szulc, Z.M.3    Bielawski, J.4    Becker, K.P.5    Bielawska, A.6    Galadari, S.H.7    Hu, W.8    Obeid, L.M.9
  • 57
    • 0030479325 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification of the first molecular lesion causing Farber disease
    • Koch, J., S. Gartner, C. M. Li, L. E. Quintern, K. Bernardo, O. Levran, D. Schnabel, R. J. Desnick, E. H. Schuchman, and K. Sandhoff. 1996. Molecular cloning and characterization of a full-length complementary DNA encoding human acid ceramidase. Identification of the first molecular lesion causing Farber disease. J. Biol. Chem. 271: 33110-33115.
    • (1996) J. Biol. Chem. , vol.271 , pp. 33110-33115
    • Koch, J.1    Gartner, S.2    Li, C.M.3    Quintern, L.E.4    Bernardo, K.5    Levran, O.6    Schnabel, D.7    Desnick, R.J.8    Schuchman, E.H.9    Sandhoff, K.10
  • 59
    • 33748665711 scopus 로고    scopus 로고
    • Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P
    • DOI 10.1096/fj.05-5689com
    • Xu, R., J. Jin, W. Hu, W. Sun, J. Bielawski, Z. Szulc, T. Taha, L. M. Obeid, and C. Mao. 2006. Golgi alkaline ceramidase regulates cell proliferation and survival by controlling levels of sphingosine and S1P. FASEB J. 20: 1813-1825. (Pubitemid 44933795)
    • (2006) FASEB Journal , vol.20 , Issue.11 , pp. 1813-1825
    • Xu, R.1    Jin, J.2    Hu, W.3    Sun, W.4    Bielawski, J.5    Szulc, Z.6    Taha, T.7    Obeid, L.M.8    Mao, C.9
  • 60
    • 0035854766 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide
    • Mao, C., R. Xu, Z. M. Szulc, A. Bielawska, S. H. Galadari, and L. M. Obeid. 2001. Cloning and characterization of a novel human alkaline ceramidase. A mammalian enzyme that hydrolyzes phytoceramide. J. Biol. Chem. 276: 26577-26588.
    • (2001) J. Biol. Chem. , vol.276 , pp. 26577-26588
    • Mao, C.1    Xu, R.2    Szulc, Z.M.3    Bielawska, A.4    Galadari, S.H.5    Obeid, L.M.6
  • 63
    • 0029895408 scopus 로고    scopus 로고
    • The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): Cloning, characterization, and assignment to human chromosome 4, band q26
    • DOI 10.1006/geno.1996.0242
    • Bosio, A., E. Binczek, M. M. Le Beau, A. A. Fernald, and W. Stoffel. 1996. The human gene CGT encoding the UDP-galactose ceramide galactosyl transferase (cerebroside synthase): cloning, characterization, and assignment to human chromosome 4, band q26. Genomics. 34: 69-75. (Pubitemid 26159882)
    • (1996) Genomics , vol.34 , Issue.1 , pp. 69-75
    • Bosio, A.1    Binczek, E.2    Le, B.M.M.3    Fernald, A.A.4    Stoffel, W.5
  • 66
    • 0347611095 scopus 로고    scopus 로고
    • Molecular machinery for non-vesicular trafficking of ceramide
    • DOI 10.1038/nature02188
    • Hanada, K., K. Kumagai, S. Yasuda, Y. Miura, M. Kawano, M. Fukasawa, and M. Nishijima. 2003. Molecular machinery for nonvesicular trafficking of ceramide. Nature. 426: 803-809. (Pubitemid 38056858)
    • (2003) Nature , vol.426 , Issue.6968 , pp. 803-809
    • Hanada, K.1    Kumagai, K.2    Yasuda, S.3    Miura, Y.4    Kawano, M.5    Fukasawa, M.6    Nishijima, M.7
  • 67
    • 0025819971 scopus 로고
    • Human acid sphingomyelinase. Isolation, nucleotide sequence and expression of the full-length and alternatively spliced cDNAs
    • Schuchman, E. H., M. Suchi, T. Takahashi, K. Sandhoff, and R. J. Desnick. 1991. Human acid sphingomyelinase. Isolation, nucleotide sequence and expression of the full-length and alternatively spliced cDNAs. J. Biol. Chem. 266: 8531-8539.
    • (1991) J. Biol. Chem. , vol.266 , pp. 8531-8539
    • Schuchman, E.H.1    Suchi, M.2    Takahashi, T.3    Sandhoff, K.4    Desnick, R.J.5
  • 71
    • 33646018341 scopus 로고    scopus 로고
    • Fatty acid elongases in mammals: Their regulation and roles in metabolism
    • Jakobsson, A., R. Westerberg, and A. Jacobsson. 2006. Fatty acid elongases in mammals: their regulation and roles in metabolism. Prog. Lipid Res. 45: 237-249.
    • (2006) Prog. Lipid Res. , vol.45 , pp. 237-249
    • Jakobsson, A.1    Westerberg, R.2    Jacobsson, A.3
  • 74
    • 77950541324 scopus 로고    scopus 로고
    • Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control
    • Han, S., M. A. Lone, R. Schneiter, and A. Chang. 2010. Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control. Proc. Natl. Acad. Sci. USA. 107: 5851-5856.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 5851-5856
    • Han, S.1    Lone, M.A.2    Schneiter, R.3    Chang, A.4
  • 76
    • 33644822862 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas
    • Bredel, M., C. Bredel, D. Juric, G. E. Duran, R. X. Yu, G. R. Harsh, H. Vogel, L. D. Recht, A. C. Scheck, and B. I. Sikic. 2006. Tumor necrosis factor-alpha-induced protein 3 as a putative regulator of nuclear factor-kappaB-mediated resistance to O6-alkylating agents in human glioblastomas. J. Clin. Oncol. 24: 274-287.
    • (2006) J. Clin. Oncol. , vol.24 , pp. 274-287
    • Bredel, M.1    Bredel, C.2    Juric, D.3    Duran, G.E.4    Yu, R.X.5    Harsh, G.R.6    Vogel, H.7    Recht, L.D.8    Scheck, A.C.9    Sikic, B.I.10
  • 77
    • 34447324918 scopus 로고    scopus 로고
    • Human gliosarcoma-associated ganglioside composition is complex and distinctive as evidenced by high-performance mass spectrometric determination and structural characterization
    • Vukelic, Z., S. Kalanj-Bognar, M. Froesch, L. Bindila, B. Radic, M. Allen, J. Peter-Katalinic, and A. D. Zamfir. 2007. Human gliosarcoma-associated ganglioside composition is complex and distinctive as evidenced by high-performance mass spectrometric determination and structural characterization. Glycobiology. 17: 504-515.
    • (2007) Glycobiology , vol.17 , pp. 504-515
    • Vukelic, Z.1    Kalanj-Bognar, S.2    Froesch, M.3    Bindila, L.4    Radic, B.5    Allen, M.6    Peter-Katalinic, J.7    Zamfir, A.D.8
  • 78
    • 0028100129 scopus 로고
    • Gangliosides as diagnostic markers of human astrocytomas and primitive neuroectodermal tumors
    • Sung, C. C., D. K. Pearl, S. W. Coons, B. W. Scheithauer, P. C. Johnson, and A. J. Yates. 1994. Gangliosides as diagnostic markers of human astrocytomas and primitive neuroectodermal tumors. Cancer. 74: 3010-3022.
    • (1994) Cancer , vol.74 , pp. 3010-3022
    • Sung, C.C.1    Pearl, D.K.2    Coons, S.W.3    Scheithauer, B.W.4    Johnson, P.C.5    Yates, A.J.6
  • 79
    • 32944462571 scopus 로고    scopus 로고
    • Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas
    • Hendrix, N. D., R. Wu, R. Kuick, D. R. Schwartz, E. R. Fearon, and K. R. Cho. 2006. Fibroblast growth factor 9 has oncogenic activity and is a downstream target of Wnt signaling in ovarian endometrioid adenocarcinomas. Cancer Res. 66: 1354-1362.
    • (2006) Cancer Res. , vol.66 , pp. 1354-1362
    • Hendrix, N.D.1    Wu, R.2    Kuick, R.3    Schwartz, D.R.4    Fearon, E.R.5    Cho, K.R.6
  • 80
    • 0026558358 scopus 로고
    • Glycosphingolipids of various human ovarian tumors: A significantly high expression of I3SO3GalCer and Lewis antigen in mucinous cystadenocarcinoma
    • Kiguchi, K., K. Takamatsu, J. Tanaka, S. Nozawa, M. Iwamori, and Y. Nagai. 1992. Glycosphingolipids of various human ovarian tumors: a significantly high expression of I3SO3GalCer and Lewis antigen in mucinous cystadenocarcinoma. Cancer Res. 52: 416-421.
    • (1992) Cancer Res. , vol.52 , pp. 416-421
    • Kiguchi, K.1    Takamatsu, K.2    Tanaka, J.3    Nozawa, S.4    Iwamori, M.5    Nagai, Y.6
  • 81
    • 0023749846 scopus 로고
    • Recognition of galactosylgloboside by monoclonal antibodies derived from patients with primary lung cancer
    • Schrump, D. S., K. Furukawa, H. Yamaguchi, K. O. Lloyd, and L. J. Old. 1988. Recognition of galactosylgloboside by monoclonal antibodies derived from patients with primary lung cancer. Proc. Natl. Acad. Sci. USA. 85: 4441-4445.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 4441-4445
    • Schrump, D.S.1    Furukawa, K.2    Yamaguchi, H.3    Lloyd, K.O.4    Old, L.J.5
  • 83
    • 42449113079 scopus 로고    scopus 로고
    • Ganglioside signatures of primary and nodal metastatic melanoma cell lines from the same patient
    • DOI 10.1097/CMR.0b013e3282f43acf, PII 0000839020080200000008
    • Ravindranath, M. H., S. Muthugounder, and N. Presser. 2008. Ganglioside signatures of primary and nodal metastatic melanoma cell lines from the same patient. Melanoma Res. 18: 47-55. (Pubitemid 351628056)
    • (2008) Melanoma Research , vol.18 , Issue.1 , pp. 47-55
    • Ravindranath, M.H.1    Muthugounder, S.2    Presser, N.3
  • 84
    • 50049091840 scopus 로고    scopus 로고
    • Quantitation of fatty acyl-coenzyme As in mammalian cells by liquid chromatography-electrospray ionization tandem mass spectrometry
    • Haynes, C. A., J. C. Allegood, K. Sims, E. W. Wang, M. C. Sullards, and A. H. Merrill, Jr. 2008. Quantitation of fatty acyl-coenzyme As in mammalian cells by liquid chromatography-electrospray ionization tandem mass spectrometry. J. Lipid Res. 49: 1113-1125.
    • (2008) J. Lipid Res. , vol.49 , pp. 1113-1125
    • Haynes, C.A.1    Allegood, J.C.2    Sims, K.3    Wang, E.W.4    Sullards, M.C.5    Merrill Jr., A.H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.