Effect of the release from mechanical stress on osteoclastogenesis in RAW264.7 cells

International Journal of Molecular Medicine

Volumn 28, Issue 1, 2011, Pages 73-79

  Shibata, Kenjiro ^a   Yoshimura, Yoshitaka ^a   Kikuiri, Takashi ^a   Hasegawa, Tomokazu ^b   Taniguchi, Yumi ^a   Deyama, Yoshiaki ^a   Suzuki, Kuniaki ^a   Iida, Junichiro ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b IWATE MEDICAL UNIVERSITY   (Japan)

Author keywords

Mechanical stress; Nitric oxide; Osteoclast

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CALCITONIN RECEPTOR; CARRIER PROTEIN; CATHEPSIN K; CHLORIDE CHANNEL; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITRIC OXIDE; TRANSCRIPTION FACTOR NFAT;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FUSION; CONTROLLED STUDY; GENE EXPRESSION PROFILING; MECHANICAL STRESS; MOUSE; NONHUMAN; OSTEOCLAST; OSTEOCLASTOGENESIS; PRIORITY JOURNAL; UPREGULATION;

ACID PHOSPHATASE; ANIMALS; CATHEPSIN K; CELL DIFFERENTIATION; CELL LINE; CHLORIDE CHANNELS; GENE EXPRESSION; ISOENZYMES; MATRIX METALLOPROTEINASE 9; MEMBRANE PROTEINS; MICE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OSTEOCLASTS; PRESSURE; RECEPTORS, CALCITONIN; STRESS, MECHANICAL; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 79955842169     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2011.675     Document Type: Article

References (45)

1. Karsenty G and Wagner EF: Reaching a genetic and molecular understanding of skeletal development. Dev Cell 2: 389-406, 2002. (Pubitemid 34436569)
2. Teitelbaum SL and Ross FP: Genetic regulation of osteoclast development and function. Nat Rev Genet 4: 638-649, 2003. (Pubitemid 36917505)
3. Nakashima T and Takayanagi H: Osteoclasts and the immune system. J Bone Miner Metab 27: 519-529, 2009.
4. Nakashima T and Takayanagi H: Osteoimmunology: crosstalk between the immune and bone systems. J Clin Immunol 29: 555-567, 2009.
5. Yasuda H, Shima N, Nakagawa N, et al: Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 95: 3597-3602, 1998.
6. Yoshida H, Hayashi S, Kunisada T, et al: The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 345: 442-444, 1990. (Pubitemid 120014957)
7. Takayanagi H, Kim S, Koga T, et al: Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts. Dev Cell 3: 889-901, 2002. (Pubitemid 35460788)
8. Asagiri M, Sato K, Usami T, et al: Autoamplification of NFATc1 expression determines its essential role in bone homeostasis. J Exp Med 9: 1261-1269, 2005. (Pubitemid 41586956)
9. Takayanagi H: Mechanistic insight into osteoclast differentiation in osteoimmunology. J Mol Med 83: 170-179, 2005.
10. Ehrlich PJ and Lanyon LE: Mechanical strain and bone cell function: a review. Osteoporos Int 13: 688-700, 2002. (Pubitemid 35000996)
11. Schneider V, Oganov V, LeBlanc A, et al: Bone and body mass changes during space flight. Acta Astronaut 36: 463-466, 1995.
12. Srinivasan S, Weimer DA, Agans SC, Bain SD and Gross TS: Low-magnitude mechanical loading becomes osteogenic when rest is inserted between each load cycle. J Bone Miner Res 17: 1613-1620, 2002.
13. Mehrotra M, Saegusa M, Wadhwa S, Voznesensky O, Peterson D and Pilbeam C: Fluid flow induces RANKL expression in primary murine calvarial osteoclasts. J Cell Biochem 98: 1271-1283, 2006. (Pubitemid 44128365)
14. Tan SD, de Vries TJ, Kuijpers-Jagtman AM, Semeins CM, Everts V and Klein-Nulend J: Osteocytes subjected to fluid flow inhibit osteoclast formation and bone resorption. Bone 41: 745-751, 2007. (Pubitemid 47576844)
15. Ichimiya H, Takahashi T, Ariyoshi W, et al: Compressive mechanical stress promotes osteoclast formation through RANKL expression on synovial cells. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103: 334-341, 2007.
16. Liu J, Zhao Z, Zou L, et al: Pressure-loaded MSCs during early osteodifferentiation promote osteoclastogenesis by increase of RANKL/OPG ratio. Ann Biomed Eng 37: 794-802, 2009.
17. Kanzaki H, Chiba M, Sato A, Miyagawa A, Arai K, Nukatsuka S and Mitani H: Cyclical tensile force on periodontal ligament cells inhibits osteoclastogenesis through OPG induction. J Dent Res 85: 457-462, 2006. (Pubitemid 43799265)
18. Rubin J, Biskobing D, Fan X, Rubin C, McLeod K and Taylor WR: Pressure regulates osteoclast formation and MCSF expression in marrow culture. J Cell Physiol 170: 81-87, 1997.
19. Makihira S, Kawahara Y, Yuge L, Mine Y and Nikawa H: Impact of the microgravity environment in a 3-dimensional clinostat on osteoblast- and osteoclast-like cells. Cell Biol Int 32: 1176-1181, 2008.
20. Kadow-Romacker A, Hoffmann JE, Duda G, Wildemann B and Schmidmaier G: Effect of mechanical stimulation on osteoblast- and osteoclast-like cells in vitro. Cells Tissues Organs 190: 61-68, 2009.
21. Kurata K, Uemura T, Nemoto A, et al: Mechanical strain effect on bone-resorbing activity and messenger RNA expressions of marker enzymes in isolated osteoclast culture. J Bone Miner Res 16: 722-730, 2001.
22. Robling AG, Niziolek PJ, Baldridge LA, et al: Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin. J Biol Chem 283: 5866-5875, 2008.
23. Inoue D, Kido S and Matsumoto T: Transcriptional induction of FosB/DeltaFosB gene by mechanical stress in osteoblasts. J Biol Chem 279: 49795-49803, 2004
24. Rubin J, Murphy TC, Fan X, Goldschmidt M and Taylor WR: Activation of extracellular signal-regulated kinase is involved in mechanical strain inhibition of RANKL expression in bone stromal cells. J Bone Miner Res 17: 1452-1460, 2002.
25. Rahnert J, Fan X, Case N, Murphy TC, Grassi F, Sen B and Rubin J: The role of nitric oxide in the mechanical repression of RANKL in bone stromal cells. Bone 43: 48-54, 2008.
26. Tan SD, Kuijpers-Jagtman AM, Semeins CM, et al: Fluid shear stress inhibits TNFalpha-induced osteocyte apoptosis. J Dent Res 85: 905-909, 2006.
27. Suzuki N, Yoshimura Y, Deyama Y and Suzuki K: Mechanical stress directly suppresses osteoclast differentiation in RAW264.7 cells. Int J Mol Med 21: 291-296, 2008.
28. Vande Geest JP, Di Mrtino ES and Vorp DA: An analysis of the complete strain field within Flexercell membranes. J Biomech 37: 1923-1928, 2004.
29. Nakai T, Yoshimura Y, Deyama Y and Suzuki K: Mechanical stress up-regulates RANKL expression via the VEGF autocrine pathway in osteoblastic MC3T3-E1 cells. Mol Med Rep 2: 229-234, 2009.
30. Takeyama S, Yoshimura Y, Deyama Y, Sugawara Y, Fukuda H, and Matsumoto A: Phosphate decreases osteoclastgenesis in coculture of osteoblast and bone marrow. Biochem Biophys Res Commun 282: 798-802, 2001.
31. Nakamura K, Deyama Y, Yoshimura Y, Suzuki K and Morita M: Toll-like receptor 3 ligand-induced antiviral response in mouse osteoblastic cells. Int J Mol Med 19: 771-775, 2007.
32. Aguirre JI, Plotkin LI, Gortazar AR, et al: A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction. J Biol Chem 282: 25501-25508, 2007.
33. Pitsillides AA, Rawlinson SC, Suswillo RF, Bourrin S, Zaman G and Lanyon LE: Mechanical strain-induced NO production by bone cells: a possible role in adaptive bone (re)modeling? FASEB J 9: 1614-1622, 1995.
34. Rubin J, Rubin C and Jacobs CR: Molecular pathways mediating mechanical signaling in bone. Gene 367: 1-16, 2006.
35. Galli C, Passeri G and Macaluso GM: Osteocytes and WNT: the mechanical control of bone formation. J Dent Res 89: 331-343, 2010.
36. Judex S, Gupta S and Rubin C: Regulation of mechanical signals in bone. Orthod Craniofac Res 12: 94-104, 2009.
37. Robling AG, Burr DB and Turner CH: Recovery periods restore mechanosensitivity to dynamically loaded bone. J Exp Biol 204: 3389-3399, 2001.
38. van't Hof RJ and Ralston SH: Nitric oxide and bone. Immunology 103: 255-261, 2001.
39. Bacabac RG, Smit TH, Mullender MG, Dijcks SJ, Van Loon JJ and Klein-Nulend J: Nitric oxide production by bone cells is fluid shear stress rate dependent. Biochem Biophys Res Commun 315: 823-829, 2004.
40. Wimalawansa SJ: Nitric oxide and bone. Ann NY Acad Sci 1192: 391-403, 2010.
41. Zheng H, Yu X, Osdoby PC and Osdby P: RANKL stimulates iNOS expression and NO production in developing osteoclasts: an autocrine negative feedback mechanism triggered by RANKL-induced IFN-β via NF-κB that restrains osteoclastogenesis and bone. J Biol Chem 281: 15809-15820, 2006.
42. Yagi M, Miyamoto T, Sawatani Y, et al: DCDC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells. J Exp Med 202: 345-351, 2005.
43. Mancini L, Moradi-Bidhendi N, Brandi ML, Perretti M and MacIntyre I: Modulation of the effects of osteoprotegerin (OPG) ligand in a human leukemic cell line by OPG and calcitonin. Biochem Biophys Res Commun 279: 391-397, 2000.
44. Islam S, Hassan F, Tumurkhuu G, et al: Receptor activator of nuclear factor-kappa B ligand induces osteoclast formation in RAW 264.7 macrophage cells via augmented production of macrophage-colony-stimulating factor. Microbiol Immunol 52: 585-590, 2008.
45. Ishikawa S, Arase N, Suenaga T, et al: Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR). Int Immunol 16: 1019-1025, 2004.