Receptor activator of nuclear factor-kappa B ligand induces osteoclast formation in RAW 264.7 macrophage cells via augmented production of macrophage-colony-stimulating factor

Microbiology and Immunology

Volumn 52, Issue 12, 2008, Pages 585-590

  Islam, Shamima ^a   Hassan, Ferdaus ^a   Tumurkhuu, Gantsetseg ^a   Dagvadorj, Jargalsaikhan ^a   Koide, Naoki ^a   Naiki, Yoshikazu ^a   Yoshida, Tomoaki ^a   Yokochi, Takashi ^a  

^a AICHI MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Macrophage colony stimulating factor (M CSF); Osteoclast; RAW 264.7 cells; Receptor activator of nuclear factor B ligand (RANKL); Tartrate resistant acid phosphatase (TRAP)

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; CELL SURFACE PROTEIN; COLONY STIMULATING FACTOR 1; DENDRITIC CELL SPECIFIC TRANSMEMBRANE PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN C FMS; PROTEIN C FOS; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; MACROPHAGE; MOUSE; NONHUMAN; OSTEOCLAST; PROTEIN EXPRESSION; ANIMAL; CELL DIFFERENTIATION; CELL LINE; CYTOLOGY; GENE EXPRESSION; GENETICS; IMMUNOLOGY;

ANIMALS; CELL DIFFERENTIATION; CELL LINE, TRANSFORMED; GENE EXPRESSION; MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MICE; OSTEOCLASTS; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B;

EID: 59449099018     PISSN: 03855600     EISSN: 13480421     Source Type: Journal    
DOI: 10.1111/j.1348-0421.2008.00076.x     Document Type: Article

References (21)

1. Roodman G.D. (1999) Cell biology of the osteoclast. Exp Hematol 27: 1229-41.
2. Chambers T.J. (2000) Regulation of the differentiation and function of osteoclasts. J Pathol 192: 4-13.
3. Suda T., Kobayashi K., Jimi E., Udagawa N., Takahashi N. (2001) The molecular basis of osteoclast differentiation and activation. Novartis Found Symp 232: 235-47.
4. Quinn J.M., Gillespie M.T. (2005) Modulation of osteoclast formation. Biochem Biophys Res Commun 328: 739-45.
5. Lacey D.L., Timms E., Tan H.L., Kelley M.J., Dunstan C.R., Burgess T. et al. (1998) Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93: 165-76.
6. Yasuda H., Shima N., Nakagawa N., Yamaguchi K., Kinosaki M., Mochizuki S. et al. (1998) Osteoclast differentiation factor is a ligand for osteoprotegrin/osteoclastogenesis inhibitory factor and identical to TRANCE/RANKL. Proc Natl Acad Sci USA 95: 3597-602.
7. Teitelbaum S.L. (2007) Osteoclasts: what do they do and how do they do it? Am J Pathol 170: 427-35.
8. Quinn J.M., Elliott J., Gillespie M.T., Martin T.J. (1998) A combination of osteoclast differentiation factor and macrophage-colony stimulating factor is sufficient for both human and mouse osteoclast formation in vitro. Endocrinology 139: 4424-7.
9. Maran A., Gorny G., Oursler M.J., Zhang M., Shogren K.L., Yaszemski M.J. et al. (2006) 2-methoxyestradiol inhibits differentiation and is cytotoxic to osteoclasts. J Cell Biochem 99: 425-34.
10. Srivastava S., Toraldo G., Weitzmann M.N., Cenci S., Ross F.P., Pacifici R. (2001) Estrogen decreases osteoclast formation by down-regulating receptor activator of NF-kappa B ligand (RANKL)-induced JNK activation. J Biol Chem 276: 8836-40.
11. Wei S., Teitelbaum S.L., Wang M.W., Ross F.P. (2001) Receptor activator of nuclear factor-kappaB ligand activates nuclear factor-kappaB in osteoclast precursors. Endocrinology 142: 1290-5.
12. Sugatani T., Alvarez U., Hruska K.A. (2003) PTEN regulates RANKL- and osteopontin-stimulated signal transduction during osteoclast differentiation and cell motility. J Biol Chem 278: 5001-8.
13. Toyomura T., Murata Y., Yamamoto A., Oka T., Sun-Wada G.H., Wada Y. et al. (2003) From lysosomes to the plasma membrane: localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiation. J Biol Chem278: 22 023-30.
14. Islam S., Hassan F., Tumurkhuu G., Dagvadorj J., Koide N., Naiki Y. et al. (2007) Bacterial lipopolysaccharide induces osteoclast formation in RAW264.7 macrophage cells. Biochem Biophys Res Commun 360: 346-51.
15. Arai F., Miyamoto T., Ohneda O., Inada T., Sudo T., Brasel K. et al. (1999) Commitment and differentiation of osteoclast precursor cells by the sequential expression of c-Fms and receptor activator of nuclear factor-kappaB (RANK) receptors. J Exp Med 190: 1741-54.
16. Takayanagi H., Kim S., Matsuo K., Suzuki H., Suzuki T., Sato K. et al. (2002) RANKL maintains bone homeostasis through c-Fos-dependent induction of interferon-beta. Nature 416: 744-9.
17. Hammarstrom L.E., Hanker J.S., Toverud S.U. (1971) Cellular differences in acid phosphatase isoenzymes in bone and teeth. Clin. Orthop Relat Res 78: 151-67.
18. Minkin C. (1982) Bone acid phosphatase: tartrate-resistant acid phosphatase as a marker of osteoclast function. Calcif Tissue Int 34: 285-90.
19. Kukita T., Wada N., Kukita A., Kakimoto T., Sandra F., Toh K. et al. (2004) RANKL-induced DC-STAMP is essential for osteoclastogenesis. J Exp Med 200: 941-6.
20. Yang M., Birnbaum M.J., MacKay C.A., Mason-Savas A., Thompson B., Odgren P.R. (2008) Osteoclast stimulatory transmembrane protein (OC-STAMP), a novel protein induced by RANKL that promotes osteoclast differentiation. J Cell Physiol 215: 497-505.
21. Hotokezaka H., Sakai E., Ohara N., Hotokezaka Y., Gonzales C., Matsuo K. et al. (2007) Molecular analysis of RANKL-independent cell fusion of osteoclast-like cells induced by TNF-alpha, lipopolysaccharide, or peptidoglycan. J Cell Biochem 101: 122-34.