메뉴 건너뛰기




Volumn 22, Issue 3-4, 2011, Pages 197-208

The importance of context to the genetic architecture of diabetes-related traits is revealed in a genome-wide scan of a LG/J × SM/J murine model

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

EID: 79955780656     PISSN: 09388990     EISSN: 14321777     Source Type: Journal    
DOI: 10.1007/s00335-010-9313-3     Document Type: Article
Times cited : (31)

References (53)
  • 2
    • 0033624575 scopus 로고    scopus 로고
    • The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes
    • Altshuler D, Hirschhorn JN, Klannemark M, Lindgren CM, Vohl MC et al (2000) The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes. Nat Genet 26:76-80
    • (2000) Nat Genet , vol.26 , pp. 76-80
    • Altshuler, D.1    Hirschhorn, J.N.2    Klannemark, M.3    Lindgren, C.M.4    Vohl, M.C.5
  • 6
    • 9444270960 scopus 로고    scopus 로고
    • Quantitative trait loci for obesity- and diabetes-related traits and their dietary responses to high-fat feeding in LGXSM recombinant inbred mouse strains
    • DOI 10.2337/diabetes.53.12.3328
    • Cheverud JM, Ehrich TH, Hrbek T, Kenney JP, Pletscher LS et al (2004) Quantitative trait loci for obesity- and diabetes-related traits and their dietary responses to high-fat feeding in LGXSM recombinant inbred mouse strains. Diabetes 53: 3328-3336 (Pubitemid 39564512)
    • (2004) Diabetes , vol.53 , Issue.12 , pp. 3328-3336
    • Cheverud, J.M.1    Ehrich, T.H.2    Hrbek, T.3    Kenney, J.P.4    Pletscher, L.S.5    Semenkovich, C.F.6
  • 7
    • 77951041217 scopus 로고    scopus 로고
    • Calpain-10 is a component of the obesity-related quantitative trait locus, Adip1
    • Cheverud JM, Fawcett GL, Jarvis JP, Norgard EA, Pavlicev M et al (2010) Calpain-10 is a component of the obesity-related quantitative trait locus, Adip1. J Lipid Res 51(5):907-913
    • (2010) J Lipid Res , vol.51 , Issue.5 , pp. 907-913
    • Cheverud, J.M.1    Fawcett, G.L.2    Jarvis, J.P.3    Norgard, E.A.4    Pavlicev, M.5
  • 8
    • 78650676945 scopus 로고    scopus 로고
    • Diet-dependent genetic and genomic imprinting effects on obesity in mice
    • Cheverud JM, Lawson HA, Fawcett G, Wang B, Pletscher LS et al (2011) Diet-dependent genetic and genomic imprinting effects on obesity in mice. Obesity 19(1):160-170
    • (2011) Obesity , vol.19 , Issue.1 , pp. 160-170
    • Cheverud, J.M.1    Lawson, H.A.2    Fawcett, G.3    Wang, B.4    Pletscher, L.S.5
  • 9
    • 33846892749 scopus 로고    scopus 로고
    • The genetic landscape of type 2 diabetes in mice
    • DOI 10.1210/er.2006-0035
    • Clee SM, Attie AD (2007) The genetic landscape of type 2 diabetes in mice. Endocr Rev 28:48-83 (Pubitemid 46220850)
    • (2007) Endocrine Reviews , vol.28 , Issue.1 , pp. 48-83
    • Clee, S.M.1    Attie, A.D.2
  • 12
    • 20044390391 scopus 로고    scopus 로고
    • Fine-mapping gene-by-diet interactions on chromosome 13 in a LG/J x SM/J murine model of obesity
    • DOI 10.2337/diabetes.54.6.1863
    • Ehrich TH, Hrbek T, Kenney-Hunt JP, Pletscher LS, Wang B et al (2005) Fine-mapping gene-by-diet interactions on chromosome 13 in a LG/J 9 SM/J murine model of obesity. Diabetes 54:1863-1872 (Pubitemid 40770778)
    • (2005) Diabetes , vol.54 , Issue.6 , pp. 1863-1872
    • Ehrich, T.H.1    Hrbek, T.2    Kenney-Hunt, J.P.3    Pletscher, L.S.4    Wang, B.5    Semenkovich, C.F.6    Cheverud, J.M.7
  • 15
    • 48749098611 scopus 로고    scopus 로고
    • Genetic architecture of adiposity and organ weight using combined generation QTL analysis
    • Fawcett GL, Roseman CC, Jarvis JP, Wang B, Wolf JB et al (2008) Genetic architecture of adiposity and organ weight using combined generation QTL analysis. Obesity (Silver Spring) 16:1861-1868
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 1861-1868
    • Fawcett, G.L.1    Roseman, C.C.2    Jarvis, J.P.3    Wang, B.4    Wolf, J.B.5
  • 16
    • 77954144468 scopus 로고    scopus 로고
    • Fine-mapping of obesity-related quantitative trait loci in an F9/10 advanced intercross line
    • Fawcett GL, Jarvis JP, Roseman CC, Wang B, Wolf JB et al (2009) Fine-mapping of obesity-related quantitative trait loci in an F9/10 advanced intercross line. Obesity (Silver Spring) 18(7):1383-1392
    • (2009) Obesity (Silver Spring) , vol.18 , Issue.7 , pp. 1383-1392
    • Fawcett, G.L.1    Jarvis, J.P.2    Roseman, C.C.3    Wang, B.4    Wolf, J.B.5
  • 17
    • 0000062670 scopus 로고
    • Progress report on possibilities in progeny-test breeding
    • Goodale HD (1941) Progress report on possibilities in progeny-test breeding. Science 94:442-443
    • (1941) Science , vol.94 , pp. 442-443
    • Goodale, H.D.1
  • 18
    • 64749101410 scopus 로고    scopus 로고
    • Relative contribution of additive, dominance, and imprinting effects to phenotypic variation in body size and growth between divergent selection lines of mice
    • Hager R, Cheverud JM, Wolf JB (2009) Relative contribution of additive, dominance, and imprinting effects to phenotypic variation in body size and growth between divergent selection lines of mice. Evolution 63:1118-1128
    • (2009) Evolution , vol.63 , pp. 1118-1128
    • Hager, R.1    Cheverud, J.M.2    Wolf, J.B.3
  • 19
    • 33646942472 scopus 로고
    • A simple regression method for mapping quantitative trait loci in line crosses using flanking markers
    • Haley CS, Knott SA (1992) A simple regression method for mapping quantitative trait loci in line crosses using flanking markers. Heredity 69:315-324
    • (1992) Heredity , vol.69 , pp. 315-324
    • Haley, C.S.1    Knott, S.A.2
  • 21
    • 67249117049 scopus 로고    scopus 로고
    • Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
    • Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP et al (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci USA 106:9362-9367
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 9362-9367
    • Hindorff, L.A.1    Sethupathy, P.2    Junkins, H.A.3    Ramos, E.M.4    Mehta, J.P.5
  • 22
    • 0037464795 scopus 로고    scopus 로고
    • A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1
    • DOI 10.1016/S0140-6736(03)12325-2
    • Huopio H, Otonkoski T, Vauhkonen I, Reimann F, Ashcroft FM et al (2003) A new subtype of autosomal dominant diabetes attributable to a mutation in the gene for sulfonylurea receptor 1. Lancet 361:301-307 (Pubitemid 36126191)
    • (2003) Lancet , vol.361 , Issue.9354 , pp. 301-307
    • Huopio, H.1    Otonkoski, T.2    Vauhkonen, I.3    Reimann, F.4    Ashcroft, F.M.5    Laakso, M.6
  • 23
    • 64349086606 scopus 로고    scopus 로고
    • The effects of ABCG5/G8 polymorphisms on plasma HDL cholesterol concentrations depend on smoking habit in the Boston Puerto Rican Health Study
    • Junyent M, Tucker KL, Smith CE, Garcia-Rios A, Mattei J et al (2009) The effects of ABCG5/G8 polymorphisms on plasma HDL cholesterol concentrations depend on smoking habit in the Boston Puerto Rican Health Study. J Lipid Res 50:565-573
    • (2009) J Lipid Res , vol.50 , pp. 565-573
    • Junyent, M.1    Tucker, K.L.2    Smith, C.E.3    Garcia-Rios, A.4    Mattei, J.5
  • 26
    • 57049118672 scopus 로고    scopus 로고
    • Gene-environment interactions reveal a homeostatic role for cholesterol metabolism during dietary folate perturbation in mice
    • Kitami T, Rubio R, O'Brien W, Quackenbush J, Nadeau JH (2008) Gene-environment interactions reveal a homeostatic role for cholesterol metabolism during dietary folate perturbation in mice. Physiol Genomics 35:182-190
    • (2008) Physiol Genomics , vol.35 , pp. 182-190
    • Kitami, T.1    Rubio, R.2    O'Brien, W.3    Quackenbush, J.4    Nadeau, J.H.5
  • 28
    • 77956820272 scopus 로고    scopus 로고
    • Genetic, epigenetic, and gene-by-diet interaction effects underlie variation in serum lipids in a LG/J 9 SM/J murine model
    • Lawson HA, Zelle KM, Fawcett G, Wang B, Pletscher LS et al (2010) Genetic, epigenetic, and gene-by-diet interaction effects underlie variation in serum lipids in a LG/J 9 SM/J murine model. J Lipid Res 51(10):2976-2984
    • (2010) J Lipid Res , vol.51 , Issue.10 , pp. 2976-2984
    • Lawson, H.A.1    Zelle, K.M.2    Fawcett, G.3    Wang, B.4    Pletscher, L.S.5
  • 29
    • 30744434862 scopus 로고    scopus 로고
    • Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
    • DOI 10.1038/sj.hdy.6800717, PII 6800717
    • Li J, Ji L (2005) Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix. Heredity 95:221-227 (Pubitemid 43093236)
    • (2005) Heredity , vol.95 , Issue.3 , pp. 221-227
    • Li, J.1    Ji, L.2
  • 30
    • 23844477504 scopus 로고    scopus 로고
    • Computing the minimum recombinant haplotype configuration from incomplete genotype data on a pedigree by integer linear programming
    • DOI 10.1089/cmb.2005.12.719
    • Li J, Jiang T (2005) Computing the minimum recombinant haplotype configuration from incomplete genotype data on a pedigree by integer linear programming. J Comput Biol 12:719-739 (Pubitemid 41170478)
    • (2005) Journal of Computational Biology , vol.12 , Issue.6 , pp. 719-739
    • Li, J.1    Jiang, T.2
  • 31
    • 22344440797 scopus 로고    scopus 로고
    • Genome-wide prediction of imprinted murine genes
    • DOI 10.1101/gr.3303505
    • Luedi PP, Hartemink AJ, Jirtle RL (2005) Genome-wide prediction of imprinted murine genes. Genome Res 15:875-884 (Pubitemid 41003109)
    • (2005) Genome Research , vol.15 , Issue.6 , pp. 875-884
    • Luedi, P.P.1    Hartemink, A.J.2    Jirtle, R.L.3
  • 32
    • 0000604646 scopus 로고
    • Genetics of body size and related characters
    • MacArthur J (1944) Genetics of body size and related characters. Am Naturalist 78:142-157
    • (1944) Am Naturalist , vol.78 , pp. 142-157
    • MacArthur, J.1
  • 33
    • 67651108806 scopus 로고    scopus 로고
    • The genetics of quantitative traits: Challenges and prospects
    • Mackay TF, Stone EA, Ayroles JF (2009) The genetics of quantitative traits: Challenges and prospects. Nat Rev Genet 10:565-577
    • (2009) Nat Rev Genet , vol.10 , pp. 565-577
    • Mackay, T.F.1    Stone, E.A.2    Ayroles, J.F.3
  • 35
    • 25844441091 scopus 로고    scopus 로고
    • 2 families
    • DOI 10.1093/jhered/esi044
    • Mantey C, Brockmann GA, Kalm E, Reinsch N (2005) Mapping and exclusion mapping of genomic imprinting effects in mouse F2 families. J Hered 96:329-338 (Pubitemid 41399393)
    • (2005) Journal of Heredity , vol.96 , Issue.4 , pp. 329-338
    • Mantey, C.1    Brockmann, G.A.2    Kalm, E.3    Reinsch, N.4
  • 36
    • 63349087565 scopus 로고    scopus 로고
    • Genome-wide association studies in type 2 diabetes
    • McCarthy MI, Zeggini E (2009) Genome-wide association studies in type 2 diabetes. Curr Diab Rep 9:164-171
    • (2009) Curr Diab Rep , vol.9 , pp. 164-171
    • McCarthy, M.I.1    Zeggini, E.2
  • 38
    • 33644880189 scopus 로고    scopus 로고
    • National Diabetes Information Clearinghouse, Department of Health and Human Services, Bethesda, MD
    • National Diabetes Information Clearinghouse (2005) National diabetes statistics. Department of Health and Human Services, Bethesda, MD
    • (2005) National Diabetes Statistics
  • 39
    • 70349566593 scopus 로고
    • Diabetes mellitus: A 'thrifty' genotype rendered detrimental by 'progress'?
    • Neel JV (1962) Diabetes mellitus: A 'thrifty' genotype rendered detrimental by 'progress'? Am J Hum Genet 14:353-362
    • (1962) Am J Hum Genet , vol.14 , pp. 353-362
    • Neel, J.V.1
  • 40
    • 49449117191 scopus 로고    scopus 로고
    • Gene-environment interactions and susceptibility to metabolic syndrome and other chronic diseases
    • Ordovas JM, Shen J (2008) Gene-environment interactions and susceptibility to metabolic syndrome and other chronic diseases. J Periodontol 79:1508-1513
    • (2008) J Periodontol , vol.79 , pp. 1508-1513
    • Ordovas, J.M.1    Shen, J.2
  • 42
    • 59849089649 scopus 로고    scopus 로고
    • Investigating parent of origin effects in studies of type 2 diabetes and obesity
    • Rampersaud E, Mitchell BD, Naj AC, Pollin TI (2008) Investigating parent of origin effects in studies of type 2 diabetes and obesity. Curr Diab Rev 4:329-339
    • (2008) Curr Diab Rev , vol.4 , pp. 329-339
    • Rampersaud, E.1    Mitchell, B.D.2    Naj, A.C.3    Pollin, T.I.4
  • 43
    • 70249146533 scopus 로고    scopus 로고
    • Underlying genetic models of inheritance in established type 2 diabetes associations
    • Salanti G, Southam L, Altshuler D, Ardlie K, Barroso I et al (2009) Underlying genetic models of inheritance in established type 2 diabetes associations. Am J Epidemiol 170:537-545
    • (2009) Am J Epidemiol , vol.170 , pp. 537-545
    • Salanti, G.1    Southam, L.2    Altshuler, D.3    Ardlie, K.4    Barroso, I.5
  • 44
    • 58149396842 scopus 로고    scopus 로고
    • Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis
    • Shao H, Burrage LC, Sinasac DS, Hill AE, Ernest SR et al (2008) Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis. Proc Natl Acad Sci USA 105:19910-19914
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19910-19914
    • Shao, H.1    Burrage, L.C.2    Sinasac, D.S.3    Hill, A.E.4    Ernest, S.R.5
  • 46
    • 0032887888 scopus 로고    scopus 로고
    • Gender-influenced obesity QTLs identified in a cross involving the KK type II diabetes-prone mouse strain
    • DOI 10.1007/s003359901141
    • Taylor BA, Tarantino LM, Phillips SJ (1999) Gender-influenced obesity QTLs identified in a cross involving the KK type II diabetes-prone mouse strain. Mamm Genome 10:963-968 (Pubitemid 29470936)
    • (1999) Mammalian Genome , vol.10 , Issue.10 , pp. 963-968
    • Taylor, B.A.1    Tarantino, L.M.2    Phillips, S.J.3
  • 48
    • 74249123592 scopus 로고    scopus 로고
    • The role of GNAS and other imprinted genes in the development of obesity
    • Weinstein LS, Xie T, Qasem A, Wang J, Chen M (2009) The role of GNAS and other imprinted genes in the development of obesity. Int J Obes 34(1):6-17
    • (2009) Int J Obes , vol.34 , Issue.1 , pp. 6-17
    • Weinstein, L.S.1    Xie, T.2    Qasem, A.3    Wang, J.4    Chen, M.5
  • 50
    • 63849179089 scopus 로고    scopus 로고
    • Genomic imprinting effects on complex traits: A phenotype-based perspective
    • Wolf JB, Hager R, Cheverud JM (2008) Genomic imprinting effects on complex traits: A phenotype-based perspective. Epigenetics 3:295-299
    • (2008) Epigenetics , vol.3 , pp. 295-299
    • Wolf, J.B.1    Hager, R.2    Cheverud, J.M.3
  • 51
    • 65949099101 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus: New genetic insights will lead to new therapeutics
    • Wolfs MG, Hofker MH, Wijmenga C, van Haeften TW (2009) Type 2 diabetes mellitus: New genetic insights will lead to new therapeutics. Curr Genomics 10:110-118
    • (2009) Curr Genomics , vol.10 , pp. 110-118
    • Wolfs, M.G.1    Hofker, M.H.2    Wijmenga, C.3    Van Haeften, T.W.4
  • 52
    • 42449121047 scopus 로고    scopus 로고
    • sα imprint control region
    • DOI 10.1210/en.2007-1458
    • Xie T, Chen M, Gavrilova O, Lai EW, Liu J et al (2008) Severe obesity and insulin resistance due to deletion of the maternal Gsalpha allele is reversed by paternal deletion of the Gsalpha imprint control region. Endocrinology 149:2443-2450 (Pubitemid 351574490)
    • (2008) Endocrinology , vol.149 , Issue.5 , pp. 2443-2450
    • Xie, T.1    Chen, M.2    Gavrilova, O.3    Lai, E.W.4    Liu, J.5    Weinstein, L.S.6
  • 53
    • 0030239728 scopus 로고    scopus 로고
    • 2 intercross
    • York B, Lei K, West DB (1996) Sensitivity to dietary obesity linked to a locus on chromosome 15 in a CAST/Ei 9 C57BL/6J F2 intercross. Mamm Genome 7:677-681 (Pubitemid 126443505)
    • (1996) Mammalian Genome , vol.7 , Issue.9 , pp. 677-681
    • York, B.1    Lei, K.2    West, D.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.