Nonlinear intestinal absorption of 5-hydroxytryptamine receptor antagonist caused by absorptive and secretory transporters

Journal of Pharmacology and Experimental Therapeutics

Volumn 283, Issue 1, 1997, Pages 108-115

  Tamai, Ikumi ^a   Saheki, Ayaka ^a   Saitoh, Ryoichi ^a   Sai, Yoshimichi ^a   Yamada, Ichimaro ^b   Tsuji, Akira ^a  

^a KANAZAWA UNIVERSITY   (Japan)

^b Yoshitomi Pharmaceutical Industries Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AZASETRON; SEROTONIN ANTAGONIST;

ADENOCARCINOMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOAVAILABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENZYME INHIBITION; EPITHELIUM CELL; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; LIPOPHILICITY; LIVER METABOLISM; MONOLAYER CULTURE; MULTIDRUG RESISTANCE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CARRIER PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, MULTIPLE; HUMANS; INTESTINAL ABSORPTION; MALE; OXAZINES; P-GLYCOPROTEIN; RATS; RATS, WISTAR; SEROTONIN ANTAGONISTS;

EID: 0030772347     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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