Inhibition of PKMζ in nucleus accumbens core abolishes long-term drug reward memory

Journal of Neuroscience

Volumn 31, Issue 14, 2011, Pages 5436-5446

  Li, Yan qin ^a,d   Xue, Yan xue ^a   He, Ying ying ^a   Li, Fang qiong ^a   Xue, Li fen ^a   Xu, Chun mei ^a   Sacktor, Todd Charlton ^b   Shaham, Yavin ^c   Lu, Lin ^a  

^a PEKING UNIVERSITY   (China)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; AMPA RECEPTOR; CHELERYTHRINE; COCAINE; GLUTAMATE RECEPTOR 2; MORPHINE; NALOXONE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PROTEIN KINASE M ZETA; STAUROSPORINE; UNCLASSIFIED DRUG; ZETA INHIBITORY PEPTIDE; 2 AMINO 5 PHOSPHOPENTANOIC ACID; 2-AMINO-5-PHOSPHOPENTANOIC ACID; AMINO ACID RECEPTOR BLOCKING AGENT; CARBOXYPIPERAZINYL PROPYLPHOSPHONIC ACID; DOPAMINE UPTAKE INHIBITOR; DRUG DERIVATIVE; ENZYME INHIBITOR; MYRISTOYL SERYL LEUCYL ASPARAGYL PROLYL GLUTAMYL TRYPTOPHYL ASPARAGYL GLUTAMYL THREONINE; MYRISTOYL-SERYL-LEUCYL-ASPARAGYL-PROLYL-GLUTAMYL-TRYPTOPHYL-ASPARAGYL-GLUTAMYL-THREONINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NARCOTIC AGENT; NARCOTIC ANTAGONIST; OLIGOPEPTIDE; PHOSPHONIC ACID DERIVATIVE; PIPERAZINE DERIVATIVE; PROTEIN KINASE C; VALINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVERSIVE BEHAVIOR; CONTROLLED STUDY; DRUG RESPONSE; DRUG SEEKING BEHAVIOR; DRUG WITHDRAWAL; ENZYME ACTIVITY; ENZYME INHIBITION; FOOD INTAKE; INSTRUMENTAL CONDITIONING; LIPID DIET; LONG TERM DRUG REWARD MEMORY; MALE; NONHUMAN; NUCLEUS ACCUMBENS; PLACE PREFERENCE; PRIORITY JOURNAL; RAT; REWARD; ANALYSIS OF VARIANCE; ANIMAL; ANIMAL BEHAVIOR; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENDOCYTOSIS; ENZYMOLOGY; MEMORY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME; WITHDRAWAL SYNDROME;

ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; COCAINE; CONDITIONING, OPERANT; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCYTOSIS; ENZYME INHIBITORS; EXCITATORY AMINO ACID ANTAGONISTS; MALE; MEMORY; MORPHINE; NALOXONE; NARCOTIC ANTAGONISTS; NARCOTICS; NUCLEUS ACCUMBENS; OLIGOPEPTIDES; PHOSPHONIC ACIDS; PIPERAZINES; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; REWARD; SUBSTANCE WITHDRAWAL SYNDROME; TIME FACTORS; VALINE;

EID: 79955717152     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5884-10.2011     Document Type: Article

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