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Volumn 20, Issue 5, 2011, Pages 387-394

Lack of association of ABCB1 and PXR polymorphisms with response to treatment in epilepsy

Author keywords

ABCB1; Antiepileptic drug; Epilepsy; P glycoprotein; Polymorphism; PXR

Indexed keywords

CARBAMAZEPINE; MULTIDRUG RESISTANCE PROTEIN 1; PREGNANE X RECEPTOR; VALPROIC ACID;

EID: 79955691266     PISSN: 10591311     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.seizure.2011.01.008     Document Type: Article
Times cited : (31)

References (45)
  • 1
    • 13244298981 scopus 로고    scopus 로고
    • Potential role of drug transporters in the pathogenesis of medically intractable epilepsy
    • DOI 10.1111/j.0013-9580.2005.31904.x
    • Kwan P, Brodie MJ. Potential role of drug transporters in the pathogenesis of medically intractable epilepsy. Epilepsia 2005;46(2):224-35. (Pubitemid 40194666)
    • (2005) Epilepsia , vol.46 , Issue.2 , pp. 224-235
    • Kwan, P.1    Brodie, M.J.2
  • 3
    • 77955323433 scopus 로고    scopus 로고
    • Blood - Brain barrier active efflux transporters: ATP-binding cassette gene family
    • Löscher W, Potschka H. Blood - brain barrier active efflux transporters: ATP-binding cassette gene family. Epilepsia 2005:1-23.
    • (2005) Epilepsia , pp. 1-23
    • Löscher, W.1    Potschka, H.2
  • 5
    • 58149231251 scopus 로고    scopus 로고
    • The clinical impact of pharmacogenetics on the treatment of epilepsy
    • Löscher W, Klotz U, Zimprich F, Schmidt D. The clinical impact of pharmacogenetics on the treatment of epilepsy. Epilepsia 2009;50(1):1-23.
    • (2009) Epilepsia , vol.50 , Issue.1 , pp. 1-23
    • Löscher, W.1    Klotz, U.2    Zimprich, F.3    Schmidt, D.4
  • 6
    • 34548726841 scopus 로고    scopus 로고
    • Silent SNPs: Impact on gene function and phenotype
    • Komar AA. Silent SNPs: impact on gene function and phenotype. Pharmacogenomics 2007;8(8):1075-80.
    • (2007) Pharmacogenomics , vol.8 , Issue.8 , pp. 1075-1080
    • Komar, A.A.1
  • 8
    • 77955325040 scopus 로고    scopus 로고
    • ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: A systematic review and meta-analysis
    • Haerian BS, Roslan H, Raymond AA, Tan CT, Zulkifli SZ, Lim KS, et al. ABCB1 C3435T polymorphism and the risk of resistance to antiepileptic drugs in epilepsy: a systematic review and meta-analysis. Seizure 2010;19:339-46.
    • (2010) Seizure , vol.19 , pp. 339-346
    • Haerian, B.S.1    Roslan, H.2    Raymond, A.A.3    Tan, C.T.4    Zulkifli, S.Z.5    Lim, K.S.6
  • 9
    • 77955847469 scopus 로고    scopus 로고
    • Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients
    • Grover S, Bala K, Sharma S, Gourie-Devi M, Baghel R, Kaur H, et al. Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients. Biochimie 2010.
    • (2010) Biochimie
    • Grover, S.1    Bala, K.2    Sharma, S.3    Gourie-Devi, M.4    Baghel, R.5    Kaur, H.6
  • 10
    • 76349096470 scopus 로고    scopus 로고
    • Genetic factors associated with drug-resistance of epilepsy: Relevance of stratification by patient age and aetiology of epilepsy
    • Sánchez MB, Herranz JL, Leno C, Arteaga R, Oterino A, Valdizán EM, et al. Genetic factors associated with drug-resistance of epilepsy: relevance of stratification by patient age and aetiology of epilepsy. Seizure 2010;19(2):93-101.
    • (2010) Seizure , vol.19 , Issue.2 , pp. 93-101
    • Sánchez, M.B.1    Herranz, J.L.2    Leno, C.3    Arteaga, R.4    Oterino, A.5    Valdizán, E.M.6
  • 15
    • 0242524432 scopus 로고    scopus 로고
    • Patterns of Human Genetic Diversity: Implications for Human Evolutionary History and Disease
    • DOI 10.1146/annurev.genom.4.070802.110226
    • Tishkoff SA, Verrelli BC. Patterns of human genetic diversity: implications for human evolutionary history and disease. Annu Rev Genomics Hum Genet 2003;4:293-340. (Pubitemid 37392927)
    • (2003) Annual Review of Genomics and Human Genetics , vol.4 , pp. 293-340
    • Tishkoff, S.A.1    Verrelli, B.C.2
  • 16
    • 21444449353 scopus 로고    scopus 로고
    • Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response
    • DOI 10.1517/14622416.6.4.411
    • Hung CC, Tai JJ, Lin CJ, Lee MJ, Liou HH. Complex haplotypic effects of the ABCB1 gene on epilepsy treatment response. Pharmacogenomics 2005;6(4):411-7. (Pubitemid 40916364)
    • (2005) Pharmacogenomics , vol.6 , Issue.4 , pp. 411-417
    • Hung, C.-C.1    Tai, J.J.2    Lin, C.-J.3    Lee, M.-J.4    Liou, H.-H.5
  • 17
    • 33745155394 scopus 로고    scopus 로고
    • ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients
    • DOI 10.2217/14622416.7.4.551
    • Seo T, Ishitsu T, Ueda N, Nakada N, Yurube K, Ueda K, et al. ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients. Pharmacogenomics 2006;7(4):551-61. (Pubitemid 43891412)
    • (2006) Pharmacogenomics , vol.7 , Issue.4 , pp. 551-561
    • Seo, T.1    Ishitsu, T.2    Ueda, N.3    Nakada, N.4    Yurube, K.5    Ueda, K.6    Nakagawa, K.7
  • 18
    • 30744472610 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the multidrug resistance 1 gene in Korean epileptics
    • DOI 10.1016/j.seizure.2005.11.001, PII S1059131105002128
    • Kim YO, Kim MK, Woo YJ, Lee MC, Kim JH, Park KW, et al. Single nucleotide polymorphisms in the multidrug resistance 1 gene in Korean epileptics. Seizure 2006;15(1):67-72. (Pubitemid 43092098)
    • (2006) Seizure , vol.15 , Issue.1 , pp. 67-72
    • Kim, Y.O.1    Kim, M.K.2    Woo, Y.J.3    Lee, M.C.4    Kim, J.H.5    Park, K.W.6    Kim, E.Y.7    Roh, Y.I.8    Kim, C.J.9
  • 19
    • 35348848498 scopus 로고    scopus 로고
    • Association of polymorphisms in NR1I2 and ABCB1 genes with epilepsy treatment responses
    • Hung CC, Jen Tai J, Kao PJ, Lin MS, Liou HH. Association of polymorphisms in NR1I2 and ABCB1 genes with epilepsy treatment responses. Pharmacogenomics 2007;8(9):1151-8.
    • (2007) Pharmacogenomics , vol.8 , Issue.9 , pp. 1151-1158
    • Hung, C.C.1    Jen Tai, J.2    Kao, P.J.3    Lin, M.S.4    Liou, H.H.5
  • 21
    • 66849129225 scopus 로고    scopus 로고
    • Gene-wide tagging study of association between ABCB1 polymorphisms and multidrug resistance in epilepsy in Han Chinese
    • Kwan P, Wong V, Ng PW, Lui CH, Sin NC, Poon WS, et al. Gene-wide tagging study of association between ABCB1 polymorphisms and multidrug resistance in epilepsy in Han Chinese. Pharmacogenomics 2009;10(5):723-32.
    • (2009) Pharmacogenomics , vol.10 , Issue.5 , pp. 723-732
    • Kwan, P.1    Wong, V.2    Ng, P.W.3    Lui, C.H.4    Sin, N.C.5    Poon, W.S.6
  • 22
    • 69949133732 scopus 로고    scopus 로고
    • Analysis of genotype and haplotype effects of ABCB1 (MDR1) polymorphisms in the risk of medically refractory epilepsy in an Indian population
    • Vahab SA, Sen S, Ravindran N, Mony S, Mathew A, Vijayan N, et al. Analysis of genotype and haplotype effects of ABCB1 (MDR1) polymorphisms in the risk of medically refractory epilepsy in an Indian population. Drug Metab Pharmacokinet 2009;24(3):255-60.
    • (2009) Drug Metab Pharmacokinet , vol.24 , Issue.3 , pp. 255-260
    • Vahab, S.A.1    Sen, S.2    Ravindran, N.3    Mony, S.4    Mathew, A.5    Vijayan, N.6
  • 23
    • 60949100347 scopus 로고    scopus 로고
    • Lack of association between ABCB1, ABCG2, and ABCC2 genetic polymorphisms and multidrug resistance in partial epilepsy
    • Kim DW, Lee SK, Chu K, Jang IJ, Yu KS, Cho JY, et al. Lack of association between ABCB1, ABCG2, and ABCC2 genetic polymorphisms and multidrug resistance in partial epilepsy. Epilepsy Res 2009;84(1):86-90.
    • (2009) Epilepsy Res , vol.84 , Issue.1 , pp. 86-90
    • Kim, D.W.1    Lee, S.K.2    Chu, K.3    Jang, I.J.4    Yu, K.S.5    Cho, J.Y.6
  • 24
    • 58149268938 scopus 로고    scopus 로고
    • No association of ABCB1 polymorphisms with drug-refractory epilepsy in a north Indian population
    • Lakhan R, Misra UK, Kalita J, Pradhan S, Gogtay NJ, Singh MK, et al. No association of ABCB1 polymorphisms with drug-refractory epilepsy in a north Indian population. Epilepsy Behav 2009;14(1):78-82.
    • (2009) Epilepsy Behav , vol.14 , Issue.1 , pp. 78-82
    • Lakhan, R.1    Misra, U.K.2    Kalita, J.3    Pradhan, S.4    Gogtay, N.J.5    Singh, M.K.6
  • 25
    • 23144435169 scopus 로고    scopus 로고
    • Genetic variants of PXR (NR1I2) and CAR (NR1I3) and their implications in drug metabolism and pharmacogenetics
    • DOI 10.2174/1389200054633880
    • Lamba J, Lamba V, Schuetz E. Genetic variants of PXR (NR1I2) and CAR (NR1I3) and their implications in drug metabolism and pharmacogenetics. Curr Drug Metab 2005;6(4):369-83. (Pubitemid 41086769)
    • (2005) Current Drug Metabolism , vol.6 , Issue.4 , pp. 369-383
    • Lamba, J.1    Lamba, V.2    Schuetz, E.3
  • 26
    • 32044444072 scopus 로고    scopus 로고
    • The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease
    • quiz 592
    • Dring MM, Goulding CA, Trimble VI, Keegan D, Ryan AW, Brophy KM, et al. The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease. Gastroenterology 2006;130(2):341-8. [quiz 592].
    • (2006) Gastroenterology , vol.130 , Issue.2 , pp. 341-348
    • Dring, M.M.1    Goulding, C.A.2    Trimble, V.I.3    Keegan, D.4    Ryan, A.W.5    Brophy, K.M.6
  • 27
    • 77951188222 scopus 로고    scopus 로고
    • Longterm changes in cyclosporine pharmacokinetics after renal transplantation in children: Evidence for saturable presystemic metabolism and effect of NR1I2 polymorphism
    • Fanta S, Jönsson S, Karlsson MO, Niemi M, Holmberg C, Hoppu K, et al. Longterm changes in cyclosporine pharmacokinetics after renal transplantation in children: evidence for saturable presystemic metabolism and effect of NR1I2 polymorphism. J Clin Pharmacol 2010;50(5):581-97.
    • (2010) J Clin Pharmacol , vol.50 , Issue.5 , pp. 581-597
    • Fanta, S.1    Jönsson, S.2    Karlsson, M.O.3    Niemi, M.4    Holmberg, C.5    Hoppu, K.6
  • 28
    • 46749128110 scopus 로고    scopus 로고
    • Influence of CYP3A5, ABCB1 and NR1I2 polymorphisms on prednisolone pharmacokinetics in renal transplant recipients
    • Miura M, Satoh S, Inoue K, Kagaya H, Saito M, Inoue T, et al. Influence of CYP3A5, ABCB1 and NR1I2 polymorphisms on prednisolone pharmacokinetics in renal transplant recipients. Steroids 2008;73(11):1052-9.
    • (2008) Steroids , vol.73 , Issue.11 , pp. 1052-1059
    • Miura, M.1    Satoh, S.2    Inoue, K.3    Kagaya, H.4    Saito, M.5    Inoue, T.6
  • 30
    • 72049100516 scopus 로고    scopus 로고
    • Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies
    • Kwan P, Arzimanoglou A, Berg AT, Brodie MJ, Hauser WA, Mathern G, et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia 2009:1-9.
    • (2009) Epilepsia , pp. 1-9
    • Kwan, P.1    Arzimanoglou, A.2    Berg, A.T.3    Brodie, M.J.4    Hauser, W.A.5    Mathern, G.6
  • 32
    • 0036667956 scopus 로고    scopus 로고
    • Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations
    • DOI 10.1097/00008571-200208000-00004
    • Tang K, Ngoi SM, Gwee PC, Chua JM, Lee EJD, Chong SS, et al. Distinct haplotype profiles and strong linkage disequilibrium at the MDR1 multidrug transporter gene locus in three ethnic Asian populations. Pharmacogenetics 2002;12:437-50. (Pubitemid 34913526)
    • (2002) Pharmacogenetics , vol.12 , Issue.6 , pp. 437-450
    • Tang, K.1    Ngoi, S.-M.2    Gwee, P.-C.3    Chua, J.M.Z.4    Lee, E.J.D.5    Chong, S.S.6    Lee, C.G.L.7
  • 34
    • 48549106023 scopus 로고    scopus 로고
    • Culture creates genetic structure in the Caucasus: Autosomal, mitochondrial, and Y-chromosomal variation in Daghestan
    • Marchani EE, Watkins WS, Bulayeva K, Harpending HC, Jorde LB. Culture creates genetic structure in the Caucasus: autosomal, mitochondrial, and Y-chromosomal variation in Daghestan. BMC Genet 2008;9:47.
    • (2008) BMC Genet , vol.9 , pp. 47
    • Marchani, E.E.1    Watkins, W.S.2    Bulayeva, K.3    Harpending, H.C.4    Jorde, L.B.5
  • 36
    • 77957969887 scopus 로고    scopus 로고
    • Ancestry and disease in the age of genomic medicine
    • Rotimi CN, Jorde LB. Ancestry and disease in the age of genomic medicine. N Engl J Med 2010;363(16):1551-8.
    • (2010) N Engl J Med , vol.363 , Issue.16 , pp. 1551-1558
    • Rotimi, C.N.1    Jorde, L.B.2
  • 37
    • 33646513294 scopus 로고    scopus 로고
    • Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds
    • Reschly EJ, Krasowski MD. Evolution and function of the NR1I nuclear hormone receptor subfamily (VDR, PXR, and CAR) with respect to metabolism of xenobiotics and endogenous compounds. Curr Drug Metab 2006;7(4):349-65.
    • (2006) Curr Drug Metab , vol.7 , Issue.4 , pp. 349-365
    • Reschly, E.J.1    Krasowski, M.D.2
  • 38
    • 0036220551 scopus 로고    scopus 로고
    • The importance of drug interactions in epilepsy therapy
    • DOI 10.1046/j.1528-1157.2002.13001.x
    • Patsalos PN, Fröscher W, Pisani F, van Rijn CM. The importance of drug interactions in epilepsy therapy. Epilepsia 2002;43(4):365-85. (Pubitemid 34297175)
    • (2002) Epilepsia , vol.43 , Issue.4 , pp. 365-385
    • Patsalos, P.N.1    Froscher, W.2    Pisani, F.3    Van Rijn, C.M.4
  • 39
    • 40849139088 scopus 로고    scopus 로고
    • Modern management of epilepsy: A practical approach
    • Elger CE, Schmidt D. Modern management of epilepsy: a practical approach. Epilepsy Behav 2008;12(4):501-39.
    • (2008) Epilepsy Behav , vol.12 , Issue.4 , pp. 501-539
    • Elger, C.E.1    Schmidt, D.2
  • 41
    • 33845866924 scopus 로고    scopus 로고
    • Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays
    • DOI 10.1124/jpet.106.102491
    • Baltes S, Fedrowitz M, Tortós CL, Potschka H, Löscher W. Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays. J Pharmacol Exp Ther 2007;320(1):331-43. (Pubitemid 46025748)
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.320 , Issue.1 , pp. 331-343
    • Baltes, S.1    Fedrowitz, M.2    Tortos, C.L.3    Potschka, H.4    Loscher, W.5
  • 42
    • 67149124051 scopus 로고    scopus 로고
    • Nonresponse to antiepileptic pharmacotherapy is associated with the ABCC2-24C > T polymorphism in young and adult patients with epilepsy
    • Ufer M, Mosyagin I, Muhle H, Jacobsen T, Haenisch S, Häsler R, et al. Nonresponse to antiepileptic pharmacotherapy is associated with the ABCC2-24C > T polymorphism in young and adult patients with epilepsy. Pharmacogenet Genomics 2009;19:353-62.
    • (2009) Pharmacogenet Genomics , vol.19 , pp. 353-362
    • Ufer, M.1    Mosyagin, I.2    Muhle, H.3    Jacobsen, T.4    Haenisch, S.5    Häsler, R.6
  • 43
    • 67649945708 scopus 로고    scopus 로고
    • Multidrugresistance genotype (ABCB1) and seizure recurrence in newly treated epilepsy: Data from International Pharmacogenetic Cohorts
    • Szoeke C, Sills GJ, Kwan P, Petrovski S, Newton M, Hitiris N, et al. Multidrugresistance genotype (ABCB1) and seizure recurrence in newly treated epilepsy: data from International Pharmacogenetic Cohorts. Epilepsia 2009.
    • (2009) Epilepsia
    • Szoeke, C.1    Sills, G.J.2    Kwan, P.3    Petrovski, S.4    Newton, M.5    Hitiris, N.6
  • 44
    • 40849094137 scopus 로고    scopus 로고
    • Increased Pglycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro
    • Yang HW, Liu HY, Liu X, Zhang DM, Liu YC, Liu XD, et al. Increased Pglycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro. Neurosci Lett 2008;434(3):299-303.
    • (2008) Neurosci Lett , vol.434 , Issue.3 , pp. 299-303
    • Yang, H.W.1    Liu, H.Y.2    Liu, X.3    Zhang, D.M.4    Liu, Y.C.5    Liu, X.D.6
  • 45


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