메뉴 건너뛰기




Volumn 26, Issue 9, 2008, Pages 2217-2228

Neural induction with neurogenin1 increases the therapeutic effects of mesenchymal stem cells in the ischemic brain

Author keywords

Mesenchymal stem cells; Neurogenin1; Stroke; Transdifferentiation; Transplantation

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; KI 67 ANTIGEN; MICROTUBULE ASSOCIATED PROTEIN 2; NEUROFILAMENT PROTEIN; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 1; VESICULAR GLUTAMATE TRANSPORTER 2; VOLTAGE GATED CALCIUM CHANNEL; VOLTAGE GATED SODIUM CHANNEL;

EID: 55049110117     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1634/stemcells.2008-0108     Document Type: Article
Times cited : (94)

References (65)
  • 1
    • 33847617021 scopus 로고    scopus 로고
    • From the laboratory bench to the patient's bedside: An update on clinical trials with mesenchymal stem cells
    • Giordano A, Galderisi U, Marino IR. From the laboratory bench to the patient's bedside: An update on clinical trials with mesenchymal stem cells. J Cell Physiol 2007;211:27-35.
    • (2007) J Cell Physiol , vol.211 , pp. 27-35
    • Giordano, A.1    Galderisi, U.2    Marino, I.R.3
  • 2
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger MF, Mackay AM, Beck SC et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-147.
    • (1999) Science , vol.284 , pp. 143-147
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 3
    • 0028788268 scopus 로고
    • Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine
    • Wakitani S, Saito T, Caplan AI. Myogenic cells derived from rat bone marrow mesenchymal stem cells exposed to 5-azacytidine. Muscle Nerve 1995;18:1417-1426.
    • (1995) Muscle Nerve , vol.18 , pp. 1417-1426
    • Wakitani, S.1    Saito, T.2    Caplan, A.I.3
  • 4
    • 0032489651 scopus 로고    scopus 로고
    • Muscle regeneration by bone marrow-derived myogenic progenitors
    • Ferrari G, Cusella-De Angelis G, Coletta M et al. Muscle regeneration by bone marrow-derived myogenic progenitors. Science 1998;279:1528-1530.
    • (1998) Science , vol.279 , pp. 1528-1530
    • Ferrari, G.1    Cusella-De Angelis, G.2    Coletta, M.3
  • 5
    • 0032584132 scopus 로고    scopus 로고
    • Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats - similarities to astrocyte grafts
    • Azizi SA, Stokes D, Augelli BJ et al. Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats - similarities to astrocyte grafts. Proc Natl Acad Sci U S A 1998;95:3908-3913.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 3908-3913
    • Azizi, S.A.1    Stokes, D.2    Augelli, B.J.3
  • 6
    • 0032874061 scopus 로고    scopus 로고
    • Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
    • Kopen GC, Prockop DJ, Phinney DG. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Natl Acad Sci U S A 1999;96:10711-10716.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 10711-10716
    • Kopen, G.C.1    Prockop, D.J.2    Phinney, D.G.3
  • 7
    • 0038787488 scopus 로고    scopus 로고
    • Marrow stromal cells, mitosis, and neuronal differentiation: Stem cell and precursor functions
    • Muñoz-Elias G, Woodbury D, Black IB. Marrow stromal cells, mitosis, and neuronal differentiation: Stem cell and precursor functions. STEM CELLS 2003;21:437-448.
    • (2003) STEM CELLS , vol.21 , pp. 437-448
    • Muñoz-Elias, G.1    Woodbury, D.2    Black, I.B.3
  • 8
    • 0034809239 scopus 로고    scopus 로고
    • In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP
    • Deng W, Obrocka M, Fischer I et al. In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. Biochem Biophys Res Commun 2001;282:148-152.
    • (2001) Biochem Biophys Res Commun , vol.282 , pp. 148-152
    • Deng, W.1    Obrocka, M.2    Fischer, I.3
  • 9
    • 0034663515 scopus 로고    scopus 로고
    • Adult rat and human bone marrow stromal cells differentiate into neurons
    • Woodbury D, Schwarz EJ, Prockop DJ et al. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 2000;61:364-370.
    • (2000) J Neurosci Res , vol.61 , pp. 364-370
    • Woodbury, D.1    Schwarz, E.J.2    Prockop, D.J.3
  • 10
    • 3042798843 scopus 로고    scopus 로고
    • Induction of bone marrow stromal cells to neurons: Differentiation, transdifferentiation, or artifact?
    • Lu P, Blesch A, Tuszynski MH. Induction of bone marrow stromal cells to neurons: Differentiation, transdifferentiation, or artifact? J Neurosci Res 2004;77:174-191.
    • (2004) J Neurosci Res , vol.77 , pp. 174-191
    • Lu, P.1    Blesch, A.2    Tuszynski, M.H.3
  • 11
    • 3042801100 scopus 로고    scopus 로고
    • Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: Disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype
    • Neuhuber B, Gallo G, Howard L et al. Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: Disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype. J Neurosci Res 2004;77:192-204.
    • (2004) J Neurosci Res , vol.77 , pp. 192-204
    • Neuhuber, B.1    Gallo, G.2    Howard, L.3
  • 12
    • 33750550464 scopus 로고    scopus 로고
    • Marrow stromal cells transplanted to the adult brain are rejected by an inflammatory response and transfer donor labels to host neurons and glia
    • Coyne TM, Marcus AJ, Woodbury D et al. Marrow stromal cells transplanted to the adult brain are rejected by an inflammatory response and transfer donor labels to host neurons and glia. STEM CELLS 2006;24:2483-2492.
    • (2006) STEM CELLS , vol.24 , pp. 2483-2492
    • Coyne, T.M.1    Marcus, A.J.2    Woodbury, D.3
  • 13
    • 0003073157 scopus 로고    scopus 로고
    • Identification of neurogenin, a vertebrate neuronal determination gene
    • Ma Q, Kintner C, Anderson DJ. Identification of neurogenin, a vertebrate neuronal determination gene. Cell 1996;87:43-52.
    • (1996) Cell , vol.87 , pp. 43-52
    • Ma, Q.1    Kintner, C.2    Anderson, D.J.3
  • 14
    • 0030611973 scopus 로고    scopus 로고
    • Mash1 and neurogenin1 expression patterns define complementary domains of neuroepithelium in the developing CNS and are correlated with regions expressing notch ligands
    • Ma Q, Sommer L, Cserjesi P et al. Mash1 and neurogenin1 expression patterns define complementary domains of neuroepithelium in the developing CNS and are correlated with regions expressing notch ligands. J Neurosci 1997;17:3644-3652.
    • (1997) J Neurosci , vol.17 , pp. 3644-3652
    • Ma, Q.1    Sommer, L.2    Cserjesi, P.3
  • 15
    • 0033967842 scopus 로고    scopus 로고
    • A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons
    • Fode C, Ma Q, Casarosa S et al. A role for neural determination genes in specifying the dorsoventral identity of telencephalic neurons. Genes Dev 2000;14:67-80.
    • (2000) Genes Dev , vol.14 , pp. 67-80
    • Fode, C.1    Ma, Q.2    Casarosa, S.3
  • 16
    • 0030268113 scopus 로고    scopus 로고
    • Sommer L, Ma Q, Anderson DJ. neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS. Mol Cell Neurosci 1996;8:221-241.
    • Sommer L, Ma Q, Anderson DJ. neurogenins, a novel family of atonal-related bHLH transcription factors, are putative mammalian neuronal determination genes that reveal progenitor cell heterogeneity in the developing CNS and PNS. Mol Cell Neurosci 1996;8:221-241.
  • 17
    • 0034051923 scopus 로고    scopus 로고
    • Generation of neurons by transient expression of neural bHLH proteins in mammalian cells
    • Farah MH, Olson JM, Sucic HB et al. Generation of neurons by transient expression of neural bHLH proteins in mammalian cells. Development 2000;127:693-702.
    • (2000) Development , vol.127 , pp. 693-702
    • Farah, M.H.1    Olson, J.M.2    Sucic, H.B.3
  • 18
    • 3343010551 scopus 로고    scopus 로고
    • Neurogenin1 is sufficient to induce neuronal differentiation of embryonal carcinoma P19 cells in the absence of retinoic acid
    • Kim S, Yoon YS, Kim JW et al. Neurogenin1 is sufficient to induce neuronal differentiation of embryonal carcinoma P19 cells in the absence of retinoic acid. Cell Mol Neurobiol 2004;24:343-356.
    • (2004) Cell Mol Neurobiol , vol.24 , pp. 343-356
    • Kim, S.1    Yoon, Y.S.2    Kim, J.W.3
  • 19
    • 0035830503 scopus 로고    scopus 로고
    • Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms
    • Sun Y, Nadal-Vicens M, Misono S et al. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 2001;104:365-376.
    • (2001) Cell , vol.104 , pp. 365-376
    • Sun, Y.1    Nadal-Vicens, M.2    Misono, S.3
  • 20
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa EZ, Weinstein PR, Carlson S et al. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989;20:84-91.
    • (1989) Stroke , vol.20 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3
  • 21
    • 33646836947 scopus 로고    scopus 로고
    • The dopamine D2 receptor regulates the development of dopaminergic neurons via extracellular signal-regulated kinase and Nurr1 activation
    • Kim SY, Choi KC, Chang MS et al. The dopamine D2 receptor regulates the development of dopaminergic neurons via extracellular signal-regulated kinase and Nurr1 activation. J Neurosci 2006;26:4567-4576.
    • (2006) J Neurosci , vol.26 , pp. 4567-4576
    • Kim, S.Y.1    Choi, K.C.2    Chang, M.S.3
  • 22
    • 0027194462 scopus 로고
    • New stereological methods for counting neurons
    • West MJ. New stereological methods for counting neurons. Neurobiol Aging 1993;14:275-285.
    • (1993) Neurobiol Aging , vol.14 , pp. 275-285
    • West, M.J.1
  • 23
    • 0033862478 scopus 로고    scopus 로고
    • Neumann-Haefelin T, Kastrup A, de Crespigny A et al. Serial MRI after transient focal cerebral ischemia in rats: Dynamics of tissue injury, blood-brain barrier damage, and edema formation. Stroke 2000;31:1965-1972; discussion 1972-1973.
    • Neumann-Haefelin T, Kastrup A, de Crespigny A et al. Serial MRI after transient focal cerebral ischemia in rats: Dynamics of tissue injury, blood-brain barrier damage, and edema formation. Stroke 2000;31:1965-1972; discussion 1972-1973.
  • 24
    • 0037183512 scopus 로고    scopus 로고
    • Human marrow stromal cell therapy for stroke in rat: Neurotrophins and functional recovery
    • Li Y, Chen J, Chen XG et al. Human marrow stromal cell therapy for stroke in rat: Neurotrophins and functional recovery. Neurology 2002;59:514-523.
    • (2002) Neurology , vol.59 , pp. 514-523
    • Li, Y.1    Chen, J.2    Chen, X.G.3
  • 25
    • 0035954362 scopus 로고    scopus 로고
    • Treatment of stroke in rat with intracarotid administration of marrow stromal cells
    • Li Y, Chen J, Wang L et al. Treatment of stroke in rat with intracarotid administration of marrow stromal cells. Neurology 2001;56:1666-1672.
    • (2001) Neurology , vol.56 , pp. 1666-1672
    • Li, Y.1    Chen, J.2    Wang, L.3
  • 26
    • 0035836656 scopus 로고    scopus 로고
    • Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat
    • Jin K, Minami M, Lan JQ et al. Neurogenesis in dentate subgranular zone and rostral subventricular zone after focal cerebral ischemia in the rat. Proc Natl Acad Sci U S A 2001;98:4710-4715.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4710-4715
    • Jin, K.1    Minami, M.2    Lan, J.Q.3
  • 27
    • 0035898233 scopus 로고    scopus 로고
    • Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia
    • Zhang RL, Zhang ZG, Zhang L et al. Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia. Neuroscience 2001;105:33-41.
    • (2001) Neuroscience , vol.105 , pp. 33-41
    • Zhang, R.L.1    Zhang, Z.G.2    Zhang, L.3
  • 28
    • 0036735672 scopus 로고    scopus 로고
    • Neuronal replacement from endogenous precursors in the adult brain after stroke
    • Arvidsson A, Collin T, Kirik D et al. Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat Med 2002;8:963-970.
    • (2002) Nat Med , vol.8 , pp. 963-970
    • Arvidsson, A.1    Collin, T.2    Kirik, D.3
  • 29
    • 13544268736 scopus 로고    scopus 로고
    • Gliosis and brain remodeling after treatment of stroke in rats with marrow stromal cells
    • Li Y, Chen J, Zhang CL et al. Gliosis and brain remodeling after treatment of stroke in rats with marrow stromal cells. Glia 2005;49:407-417.
    • (2005) Glia , vol.49 , pp. 407-417
    • Li, Y.1    Chen, J.2    Zhang, C.L.3
  • 30
    • 0028905230 scopus 로고
    • Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat
    • Li Y, Chopp M, Jiang N et al. Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab 1995;15:389-397.
    • (1995) J Cereb Blood Flow Metab , vol.15 , pp. 389-397
    • Li, Y.1    Chopp, M.2    Jiang, N.3
  • 31
    • 33744998969 scopus 로고    scopus 로고
    • Thymidine analogs are transferred from prelabeled donor to host cells in the central nervous system after transplantation: A word of caution
    • Burns TC, Ortiz-Gonzalez XR, Gutierrez-Perez M et al. Thymidine analogs are transferred from prelabeled donor to host cells in the central nervous system after transplantation: A word of caution. STEM CELLS 2006;24:1121-1127.
    • (2006) STEM CELLS , vol.24 , pp. 1121-1127
    • Burns, T.C.1    Ortiz-Gonzalez, X.R.2    Gutierrez-Perez, M.3
  • 32
    • 0037199095 scopus 로고    scopus 로고
    • Fluorescent retrograde neuronal tracers that label the rat facial nucleus: A comparison of Fast Blue, Fluoro-ruby, Fluoro-emerald, Fluoro-Gold and DiI
    • Choi D, Li D, Raisman G. Fluorescent retrograde neuronal tracers that label the rat facial nucleus: A comparison of Fast Blue, Fluoro-ruby, Fluoro-emerald, Fluoro-Gold and DiI. J Neurosci Methods 2002;117:167-172.
    • (2002) J Neurosci Methods , vol.117 , pp. 167-172
    • Choi, D.1    Li, D.2    Raisman, G.3
  • 33
    • 0034869395 scopus 로고    scopus 로고
    • A novel method for simultaneous anterograde and retrograde labeling of spinal cord motor tracts in the same animal
    • Tsai EC, van Bendegem RL, Hwang SW et al. A novel method for simultaneous anterograde and retrograde labeling of spinal cord motor tracts in the same animal. J Histochem Cytochem 2001;49:1111-1122.
    • (2001) J Histochem Cytochem , vol.49 , pp. 1111-1122
    • Tsai, E.C.1    van Bendegem, R.L.2    Hwang, S.W.3
  • 34
    • 84934435607 scopus 로고    scopus 로고
    • Immunocytochemical analysis of neuronal differentiation
    • Magavi SS, Macklis JD. Immunocytochemical analysis of neuronal differentiation. Methods Mol Biol 2008;438:345-352.
    • (2008) Methods Mol Biol , vol.438 , pp. 345-352
    • Magavi, S.S.1    Macklis, J.D.2
  • 35
    • 0036232776 scopus 로고    scopus 로고
    • Adenovirus-mediated WGA gene delivery for transsynaptic labeling of mouse olfactory pathways
    • Kinoshita N, Mizuno T, Yoshihara Y. Adenovirus-mediated WGA gene delivery for transsynaptic labeling of mouse olfactory pathways. Chem Senses 2002;27:215-223.
    • (2002) Chem Senses , vol.27 , pp. 215-223
    • Kinoshita, N.1    Mizuno, T.2    Yoshihara, Y.3
  • 36
    • 20444419744 scopus 로고    scopus 로고
    • Autologous mesenchymal stem cell transplantation in stroke patients
    • Bang OY, Lee JS, Lee PH et al. Autologous mesenchymal stem cell transplantation in stroke patients. Ann Neurol 2005;57:874-882.
    • (2005) Ann Neurol , vol.57 , pp. 874-882
    • Bang, O.Y.1    Lee, J.S.2    Lee, P.H.3
  • 37
    • 1642303117 scopus 로고    scopus 로고
    • Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells
    • Liu Y, Encinas M, Comella JX et al. Basic helix-loop-helix proteins bind to TrkB and p21(Cip1) promoters linking differentiation and cell cycle arrest in neuroblastoma cells. Mol Cell Biol 2004;24:2662-2672.
    • (2004) Mol Cell Biol , vol.24 , pp. 2662-2672
    • Liu, Y.1    Encinas, M.2    Comella, J.X.3
  • 38
    • 0037088594 scopus 로고    scopus 로고
    • Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroD
    • Ratineau C, Petry MW, Mutoh H et al. Cyclin D1 represses the basic helix-loop-helix transcription factor, BETA2/NeuroD. J Biol Chem 2002;277:8847-8853.
    • (2002) J Biol Chem , vol.277 , pp. 8847-8853
    • Ratineau, C.1    Petry, M.W.2    Mutoh, H.3
  • 39
    • 24044528210 scopus 로고    scopus 로고
    • cAMP induces neuronal differentiation of mesenchymal stem cells via activation of extracellular signal-regulated kinase/MAPK
    • Kim SS, Choi JM, Kim JW et al. cAMP induces neuronal differentiation of mesenchymal stem cells via activation of extracellular signal-regulated kinase/MAPK. Neuroreport 2005;16:1357-1361.
    • (2005) Neuroreport , vol.16 , pp. 1357-1361
    • Kim, S.S.1    Choi, J.M.2    Kim, J.W.3
  • 40
    • 0024797279 scopus 로고
    • Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons
    • Westenbroek RE, Merrick DK, Catterall WA. Differential subcellular localization of the RI and RII Na+ channel subtypes in central neurons. Neuron 1989;3:695-704.
    • (1989) Neuron , vol.3 , pp. 695-704
    • Westenbroek, R.E.1    Merrick, D.K.2    Catterall, W.A.3
  • 41
    • 0037418936 scopus 로고    scopus 로고
    • Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats
    • Chen J, Zhang ZG, Li Y et al. Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats. Circ Res 2003;92:692-699.
    • (2003) Circ Res , vol.92 , pp. 692-699
    • Chen, J.1    Zhang, Z.G.2    Li, Y.3
  • 42
    • 26944484409 scopus 로고    scopus 로고
    • Nomura T, Honmou O, Harada K et al. I.V. infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Neuroscience 2005;136:161-169.
    • Nomura T, Honmou O, Harada K et al. I.V. infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Neuroscience 2005;136:161-169.
  • 43
    • 33749455560 scopus 로고    scopus 로고
    • Neuroprotection by PlGF gene-modified human mesenchymal stem cells after cerebral ischaemia
    • Liu H, Honmou O, Harada K et al. Neuroprotection by PlGF gene-modified human mesenchymal stem cells after cerebral ischaemia. Brain 2006;129:2734-2745.
    • (2006) Brain , vol.129 , pp. 2734-2745
    • Liu, H.1    Honmou, O.2    Harada, K.3
  • 44
    • 0036708181 scopus 로고    scopus 로고
    • Human bone marrow stromal cell cultures conditioned by traumatic brain tissue extracts: Growth factor production
    • Chen X, Katakowski M, Li Y et al. Human bone marrow stromal cell cultures conditioned by traumatic brain tissue extracts: Growth factor production. J Neurosci Res 2002;69:687-691.
    • (2002) J Neurosci Res , vol.69 , pp. 687-691
    • Chen, X.1    Katakowski, M.2    Li, Y.3
  • 45
    • 0037442264 scopus 로고    scopus 로고
    • Suppression of allogeneic T-cell proliferation by human marrow stromal cells: Implications in transplantation
    • Tse WT, Pendleton JD, Beyer WM et al. Suppression of allogeneic T-cell proliferation by human marrow stromal cells: Implications in transplantation. Transplantation 2003;75:389-397.
    • (2003) Transplantation , vol.75 , pp. 389-397
    • Tse, W.T.1    Pendleton, J.D.2    Beyer, W.M.3
  • 46
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • Krampera M, Glennie S, Dyson J et al. Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 2003;101:3722-3729.
    • (2003) Blood , vol.101 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3
  • 47
    • 0018753961 scopus 로고
    • MHC-restricted cytotoxic T cells: Studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness
    • Zinkernagel RM, Doherty PC. MHC-restricted cytotoxic T cells: Studies on the biological role of polymorphic major transplantation antigens determining T-cell restriction-specificity, function, and responsiveness. Adv Immunol 1979;27:51-177.
    • (1979) Adv Immunol , vol.27 , pp. 51-177
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 48
    • 0024263476 scopus 로고
    • Suppression of human cytotoxic T lymphocyte responses by adherent peripheral blood leukocytes
    • Bernstein DC, Shearer GM. Suppression of human cytotoxic T lymphocyte responses by adherent peripheral blood leukocytes. Ann N Y Acad Sci 1988;532:207-213.
    • (1988) Ann N Y Acad Sci , vol.532 , pp. 207-213
    • Bernstein, D.C.1    Shearer, G.M.2
  • 49
    • 0035914946 scopus 로고    scopus 로고
    • Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses
    • Carlin LM, Eleme K, McCann FE et al. Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses. J Exp Med 2001;194:1507-1517.
    • (2001) J Exp Med , vol.194 , pp. 1507-1517
    • Carlin, L.M.1    Eleme, K.2    McCann, F.E.3
  • 50
    • 0041336932 scopus 로고    scopus 로고
    • Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat
    • Chen J, Li Y, Katakowski M et al. Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat. J Neurosci Res 2003;73:778-786.
    • (2003) J Neurosci Res , vol.73 , pp. 778-786
    • Chen, J.1    Li, Y.2    Katakowski, M.3
  • 51
    • 0036118625 scopus 로고    scopus 로고
    • Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats
    • Zhao LR, Duan WM, Reyes M et al. Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after grafting into the ischemic brain of rats. Exp Neurol 2002;174:11-20.
    • (2002) Exp Neurol , vol.174 , pp. 11-20
    • Zhao, L.R.1    Duan, W.M.2    Reyes, M.3
  • 52
    • 23044515099 scopus 로고    scopus 로고
    • Functions and mechanisms of retrograde neurotrophin signalling
    • Zweifel LS, Kuruvilla R, Ginty DD. Functions and mechanisms of retrograde neurotrophin signalling. Nat Rev Neurosci 2005;6:615-625.
    • (2005) Nat Rev Neurosci , vol.6 , pp. 615-625
    • Zweifel, L.S.1    Kuruvilla, R.2    Ginty, D.D.3
  • 53
    • 3542996324 scopus 로고    scopus 로고
    • Sequential phases of cortical specification involve Neurogenin-dependent and-independent pathways
    • Schuurmans C, Armant O, Nieto M et al. Sequential phases of cortical specification involve Neurogenin-dependent and-independent pathways. EMBO J 2004;23:2892-2902.
    • (2004) EMBO J , vol.23 , pp. 2892-2902
    • Schuurmans, C.1    Armant, O.2    Nieto, M.3
  • 54
    • 34250004608 scopus 로고    scopus 로고
    • Directing neurotransmitter identity of neurones derived from expanded adult neural stem cells
    • Berninger B, Guillemot F, Gotz M. Directing neurotransmitter identity of neurones derived from expanded adult neural stem cells. Eur J Neurosci 2007;25:2581-2590.
    • (2007) Eur J Neurosci , vol.25 , pp. 2581-2590
    • Berninger, B.1    Guillemot, F.2    Gotz, M.3
  • 55
    • 3042769428 scopus 로고    scopus 로고
    • Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation
    • Dezawa M, Kanno H, Hoshino M et al. Specific induction of neuronal cells from bone marrow stromal cells and application for autologous transplantation. J Clin Invest 2004;113:1701-1710.
    • (2004) J Clin Invest , vol.113 , pp. 1701-1710
    • Dezawa, M.1    Kanno, H.2    Hoshino, M.3
  • 56
    • 0029930494 scopus 로고    scopus 로고
    • Neurogenic genes and vertebrate neurogenesis
    • Lewis J. Neurogenic genes and vertebrate neurogenesis. Curr Opin Neurobiol 1996;6:3-10.
    • (1996) Curr Opin Neurobiol , vol.6 , pp. 3-10
    • Lewis, J.1
  • 57
    • 0033697009 scopus 로고    scopus 로고
    • Radial glial identity is promoted by Notch1 signaling in the murine forebrain
    • Gaiano N, Nye JS, Fishell G. Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron 2000;26:395-404.
    • (2000) Neuron , vol.26 , pp. 395-404
    • Gaiano, N.1    Nye, J.S.2    Fishell, G.3
  • 58
    • 0034716909 scopus 로고    scopus 로고
    • Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells
    • Morrison SJ, Perez SE, Qiao Z et al. Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells. Cell 2000;101:499-510.
    • (2000) Cell , vol.101 , pp. 499-510
    • Morrison, S.J.1    Perez, S.E.2    Qiao, Z.3
  • 59
    • 0033715815 scopus 로고    scopus 로고
    • rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells
    • Furukawa T, Mukherjee S, Bao ZZ et al. rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells. Neuron 2000;26:383-394.
    • (2000) Neuron , vol.26 , pp. 383-394
    • Furukawa, T.1    Mukherjee, S.2    Bao, Z.Z.3
  • 60
    • 0035139022 scopus 로고    scopus 로고
    • Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate
    • Tanigaki K, Nogaki F, Takahashi J et al. Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate. Neuron 2001;29:45-55.
    • (2001) Neuron , vol.29 , pp. 45-55
    • Tanigaki, K.1    Nogaki, F.2    Takahashi, J.3
  • 61
    • 0036023380 scopus 로고    scopus 로고
    • Notch1 is required for neuronal and glial differentiation in the cerebellum
    • Lütolf S, Radtke F, Aguet M et al. Notch1 is required for neuronal and glial differentiation in the cerebellum. Development 2002;129:373-385.
    • (2002) Development , vol.129 , pp. 373-385
    • Lütolf, S.1    Radtke, F.2    Aguet, M.3
  • 62
    • 0030933977 scopus 로고    scopus 로고
    • Conservation of the Notch signalling pathway in mammalian neurogenesis
    • de la Pompa JL, Wakeham A, Correia KM et al. Conservation of the Notch signalling pathway in mammalian neurogenesis. Development 1997;124:1139-1148.
    • (1997) Development , vol.124 , pp. 1139-1148
    • de la Pompa, J.L.1    Wakeham, A.2    Correia, K.M.3
  • 63
    • 34147198436 scopus 로고    scopus 로고
    • Antibodies to CD11b, CD68, and lectin label neutrophils rather than microglia in traumatic and ischemic brain lesions
    • Matsumoto H, Kumon Y, Watanabe H et al. Antibodies to CD11b, CD68, and lectin label neutrophils rather than microglia in traumatic and ischemic brain lesions. J Neurosci Res 2007;85:994-1009.
    • (2007) J Neurosci Res , vol.85 , pp. 994-1009
    • Matsumoto, H.1    Kumon, Y.2    Watanabe, H.3
  • 64
    • 35048867410 scopus 로고    scopus 로고
    • Resident microglia die and infiltrated neutrophils and monocytes become major inflammatory cells in lipopolysaccharide-injected brain
    • Ji KA, Yang MS, Jeong HK et al. Resident microglia die and infiltrated neutrophils and monocytes become major inflammatory cells in lipopolysaccharide-injected brain. Glia 2007;55:1577-1588.
    • (2007) Glia , vol.55 , pp. 1577-1588
    • Ji, K.A.1    Yang, M.S.2    Jeong, H.K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.