Intradermal injection of methylene blue for the treatment of refractory pruritus ani

Colorectal Disease

Volumn 11, Issue 3, 2009, Pages 282-287

  Sutherland, A D ^a   Faragher, I G ^b   Frizelle, Frank A ^a  

^a CHRISTCHURCH HOSPITAL   (New Zealand)

^b North West Hospital   (Australia)

Author keywords

Idiopathic; Methylene blue; Pruitis ani; Refractory

Indexed keywords

METHYLENE BLUE;

ADULT; AGED; ANAPHYLAXIS; ANUS PRURITUS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISTRESS SYNDROME; DRUG EFFICACY; DRUG TOLERABILITY; FECES INCONTINENCE; FEMALE; HUMAN; IDIOPATHIC DISEASE; MALE; PAIN; PERINEAL CARE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SKIN NECROSIS; SYMPTOMATOLOGY; TREATMENT FAILURE;

ADULT; AGED; BIOPSY, NEEDLE; CHRONIC DISEASE; COLONOSCOPY; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; HUMANS; INJECTIONS, INTRADERMAL; MALE; METHYLENE BLUE; MIDDLE AGED; PATIENT SATISFACTION; PROSPECTIVE STUDIES; PRURITUS ANI; RISK ASSESSMENT; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; YOUNG ADULT;

EID: 60549111668     PISSN: 14628910     EISSN: 14631318     Source Type: Journal    
DOI: 10.1111/j.1463-1318.2008.01587.x     Document Type: Article

References (23)

1. Mazier WP. Hemorrhoids, fissures and pruritus ani. Surg Clin North Am 1994; 74: 1277-92.
2. Jones DJ. Pruritus ani. BMJ 1992; 305: 575-7.
3. Harrington CJ, Lewis FM, McDonagh AJG et al. Dermatological causes of pruritus ani. BMJ 1992; 305: 955.
4. Friend WG. The cause and treatment of idiopathic pruritus ani. Dis Colon Rectum 1977; 20: 40-2.
5. Smith LE, Henrichs D, McCullah RD. Prospective studies on the etiology and treatment of pruritus ani. Dis Colon Rectum 1982; 25: 358-63.
6. Laurent A, Boucharlat J, Bosson JL et al. Psychological assessment of patients with idiopathic pruritus ani. Psychother Psychosom 1997; 66: 163-6.
7. Al-Ghnaniem R, Short K, Pullen A et al. 1% Hydrocortisone ointment is an effective treatment of pruritus ani: A pilot randomized controlled crossover trial. Int J Colorectal Dis 2007; 22: 1463-7.
8. Farouk R, Duthie GS, Pryde A, Bartolo DCC. Abnormal transient internal sphincter relaxation in idiopathic pruritus ani: Physiological evidence from ambulatory monitoring. Br J Surg 1994; 81: 603-6.
9. Allan A, Ambrose NS, Silverman S et al. Physiological study of pruritus ani. Br J Surg 1987; 74: 576-9.
10. Eyers AA, Thomson JPS. Pruritus ani: Is anal sphincter dysfunction important in aetiology? BMJ 1979; 2: 1549-51.
11. Silverman SH, Youngs DJ, Allan A et al. The fecal microflora in pruritus ani. Dis Colon Rectum 1989; 32: 466-8.
12. Clifton J, Leikin JB. Methylene blue. Am J Ther 2003; 10: 289-91.
13. Dudley NE. Methylene blue for the rapid identification of the parathyroids. BMJ 1971; 3: 680-1.
14. Wolloch Y, Dintsman M. A simple and effective method of treatment for intractable pruritus ani. Am J Proctol Gastroenterol Colon Rectal Surg 1979; 30: 34-6.
15. Eusebio EB, Graham J, Mody N. Treatment of intractable pruritus ani. Dis Colon Rectum 1990; 33: 770-2.
16. Eusebio EB. New treatment of intractable pruritus ani. Dis Colon Rectum 1991; 34: 289.
17. Farouk R, Lee PW. Intradermal methylene blue injection for the treatment of intractable idiopathic pruritus ani. Br J Surg 1997; 84: 670.
18. Botterill ID, Sagar PM. Intra-dermal methylene blue, hydrocortisone and lignocaine for chronic, intractable pruritus ani. Colorectal Dis 2002; 4: 144-6.
19. Mentes BB, Akin M, Leventoglu S et al. Intradermal methylene blue injection for the treatment of intractable idiopathic pruritus ani: results of 30 cases. Tech Coloproctol 2004; 8: 11-4.
20. Shafik A. An injection technique for the treatment of idiopathic pruritus ani. Tech Coloproctol 2004; 8: 201.
21. Mentes BB. Author's reply. Tech Coloproctol 2004; 8: 201.
22. Seow-Choen F, Tan KY. Methylene blue injection reduces pain after lateral sphincterotomy. ANZ J Surg 2007; 77 (Suppl 1): A18.
23. Lysy J, Sistiery-Ittah M, Israelit Y et al. Topical capsaicin-a novel and effective treatment for idiopathic intractable pruritus ani: A randomised, placebo controlled, crossover study. Gut 2003; 52: 1323-6.