SCOPUS 정보 검색 플랫폼

Volumn 400, Issue 5, 2011, Pages 1359-1366

Development of an online SPE-LC-MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors

(5) Schebb, Nils Helge a Huby, Marion a Morisseau, Christophe a Hwang, Sung Hee a Hammock, Bruce D a

a UNIVERSITY OF CALIFORNIA (United States)

Author keywords

Electrospray mass spectrometry tandem mass spectrometry; Enzyme inhibitors turbulent flow chromatography; Liquid chromatography; Natural substrate enzyme assay; Online solid phase extraction; Soluble epoxide hydrolase (sEH)

Indexed keywords

ENZYME INHIBITORS; NATURAL SUBSTRATES; ONLINE-SOLID PHASE EXTRACTION; SOLUBLE EPOXIDE HYDROLASE (SEH); TANDEM MASS SPECTROMETRY;

ASSAYS; ELECTROSPRAY IONIZATION; ENZYME INHIBITION; ENZYMES; FLUORESCENCE; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HYDROLASES; LIQUIDS; MASS SPECTROMETRY; SOLVENT EXTRACTION; SUBSTRATES;

CHROMATOGRAPHY;

14,15 DIHYDROXYEICOSATRIENOIC ACID; 14,15 EPOXY 5,8,11 EICOSATRIENOIC ACID; 14,15-DIHYDROXYEICOSATRIENOIC ACID; 14,15-EPOXY-5,8,11-EICOSATRIENOIC ACID; DIHOMO GAMMA LINOLENIC ACID; DRUG DERIVATIVE; ENZYME INHIBITOR; EPOXIDE HYDROLASE;

CHEMISTRY; CONFERENCE PAPER; DRUG ANTAGONISM; HUMAN; METABOLISM; METHODOLOGY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

8,11,14-EICOSATRIENOIC ACID; ENZYME INHIBITORS; EPOXIDE HYDROLASES; HUMANS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 79955550271 PISSN: 16182642 EISSN: 16182650 Source Type: Journal
DOI: 10.1007/s00216-011-4861-2 Document Type: Conference Paper

Times cited : (25)

References (39)

1
- 70349636047
- 10.1038/nrd2875 1:CAS:528:DC%2BD1MXhtF2kurnK
- JD Imig BD Hammock 2009 Nat Rev Drug Discov 8 794 805 10.1038/nrd2875 1:CAS:528:DC%2BD1MXhtF2kurnK
- (2009) Nat Rev Drug Discov , vol.8 , pp. 794-805
- Imig, J.D.¹ Hammock, B.D.²

2
- 57749091900
- 10.1073/pnas.0809765105 1:CAS:528:DC%2BD1cXhsV2rtLrI
- B Inceoglu SL Jinks A Ulu CM Hegedus K Georgi KR Schmelzer K Wagner PD Jones C Morisseau BD Hammock 2008 Proc Natl Acad Sci USA 105 18901 18906 10.1073/pnas.0809765105 1:CAS:528:DC%2BD1cXhsV2rtLrI
- (2008) Proc Natl Acad Sci USA , vol.105 , pp. 18901-18906
- Inceoglu, B.¹ Jinks, S.L.² Ulu, A.³ Hegedus, C.M.⁴ Georgi, K.⁵ Schmelzer, K.R.⁶ Wagner, K.⁷ Jones, P.D.⁸ Morisseau, C.⁹ Hammock, B.D.¹⁰

3
- 68749100411
- C Morisseau BD Hammock 2007 Curr Protoc Toxicol 33 4.23.1 4.23.18
- (2007) Curr Protoc Toxicol , vol.33 , pp. 4231-42318
- Morisseau, C.¹ Hammock, B.D.²

4
- 22144444583
- Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies
- DOI 10.1016/j.ab.2005.03.041, PII S000326970500240X
- PD Jones NM Wolf C Morisseau P Whetstone B Hock BD Hammock 2005 Anal Biochem 343 66 75 10.1016/j.ab.2005.03.041 1:CAS:528:DC%2BD2MXmtFSmsr4%3D (Pubitemid 40978610)
- (2005) Analytical Biochemistry , vol.343 , Issue.1 , pp. 66-75
- Jones, P.D.¹ Wolf, N.M.² Morisseau, C.³ Whetstone, P.⁴ Hock, B.⁵ Hammock, B.D.⁶

5
- 33745918021
- Development of a high-throughput screen for soluble epoxide hydrolase inhibition
- DOI 10.1016/j.ab.2006.04.045, PII S0003269706003265
- NM Wolf C Morisseau PD Jones B Hock BD Hammock 2006 Anal Biochem 355 71 80 10.1016/j.ab.2006.04.045 1:CAS:528:DC%2BD28XntV2mtr8%3D (Pubitemid 44041405)
- (2006) Analytical Biochemistry , vol.355 , Issue.1 , pp. 71-80
- Wolf, N.M.¹ Morisseau, C.² Jones, P.D.³ Hock, B.⁴ Hammock, B.D.⁵

6
- 0020620574
- 10.1016/0003-2697(83)90166-5 1:CAS:528:DyaL3sXkvVCjur4%3D
- SS Gill K Ota BD Hammock 1983 Anal Biochem 131 273 282 10.1016/0003-2697(83)90166-5 1:CAS:528:DyaL3sXkvVCjur4%3D
- (1983) Anal Biochem , vol.131 , pp. 273-282
- Gill, S.S.¹ Ota, K.² Hammock, B.D.³

7
- 23244467785
- Monitoring enzymatic conversions by mass spectrometry: A critical review
- DOI 10.1007/s00216-005-3305-2
- A Liesener U Karst 2005 Anal Bioanal Chem 382 1451 1464 10.1007/s00216-005-3305-2 1:CAS:528:DC%2BD2MXmsFWlt7c%3D (Pubitemid 41090448)
- (2005) Analytical and Bioanalytical Chemistry , vol.382 , Issue.7 , pp. 1451-1464
- Liesener, A.¹ Karst, U.²

8
- 37149001519
- 10.1351/pac200779122339 1:CAS:528:DC%2BD2sXhsVOgur3O
- A Liesener AM Perchuc R Schoni NH Schebb M Wilmer U Karst 2007 Pure Appl Chem 79 2339 2349 10.1351/pac200779122339 1:CAS:528:DC%2BD2sXhsVOgur3O
- (2007) Pure Appl Chem , vol.79 , pp. 2339-2349
- Liesener, A.¹ Perchuc, A.M.² Schoni, R.³ Schebb, N.H.⁴ Wilmer, M.⁵ Karst, U.⁶

9
- 66249104695
- 10.1016/j.chroma.2009.05.020 1:CAS:528:DC%2BD1MXntVShsLk%3D
- NH Schebb D Falck H Faber EM Hein U Karst H Hayen 2009 J Chromatogr A 1216 5249 5255 10.1016/j.chroma.2009.05.020 1:CAS:528:DC%2BD1MXntVShsLk%3D
- (2009) J Chromatogr A , vol.1216 , pp. 5249-5255
- Schebb, N.H.¹ Falck, D.² Faber, H.³ Hein, E.M.⁴ Karst, U.⁵ Hayen, H.⁶

10
- 64649103868
- 10.1016/j.chroma.2009.03.053 1:CAS:528:DC%2BD1MXltFWgu7c%3D
- NH Schebb T Vielhaber A Jousset U Karst 2009 J Chromatogr A 1216 4407 4415 10.1016/j.chroma.2009.03.053 1:CAS:528:DC%2BD1MXltFWgu7c%3D
- (2009) J Chromatogr A , vol.1216 , pp. 4407-4415
- Schebb, N.H.¹ Vielhaber, T.² Jousset, A.³ Karst, U.⁴

11
- 77049113003
- Siemerink M, Schebb NH, Liesener A, Perchuc AM, Schoni R, Wilmer M, Hayen H, Karst U, Vogel M (2010) Rapid Commun Mass Spectrom 24:687-97
- (2010) Rapid Commun Mass Spectrom , vol.24 , pp. 687-697
- Siemerink, M.¹ Schebb, N.H.² Liesener, A.³ Perchuc, A.M.⁴ Schoni, R.⁵ Wilmer, M.⁶ Hayen, H.⁷ Karst, U.⁸ Vogel, M.⁹

12
- 13844316739
- Epoxide hydrolases: Mechanisms, inhibitor designs, and biological roles
- DOI 10.1146/annurev.pharmtox.45.120403.095920
- C Morisseau BD Hammock 2005 Annu Rev Pharmacol Toxicol 45 311 333 10.1146/annurev.pharmtox.45.120403.095920 1:CAS:528:DC%2BD2MXisVWjt7k%3D (Pubitemid 40261808)
- (2005) Annual Review of Pharmacology and Toxicology , vol.45 , pp. 311-333
- Morisseau, C.¹ Hammock, B.D.²

13
- 14644429730
- Epoxide hydrolases: Their roles and interactions with lipid metabolism
- DOI 10.1016/j.plipres.2004.10.001
- JW Newman C Morisseau BD Hammock 2005 Prog Lipid Res 44 1 51 10.1016/j.plipres.2004.10.001 1:CAS:528:DC%2BD2MXhvVCjtLg%3D (Pubitemid 40313218)
- (2005) Progress in Lipid Research , vol.44 , Issue.1 , pp. 1-51
- Newman, J.W.¹ Morisseau, C.² Hammock, B.D.³

14
- 33750529521
- Inhibition of soluble epoxide hydrolase reduces LPS-induced thermal hyperalgesia and mechanical allodynia in a rat model of inflammatory pain
- DOI 10.1016/j.lfs.2006.07.031, PII S0024320506005972
- B Inceoglu SL Jinks KR Schmelzer T Waite IH Kim BD Hammock 2006 Life Sci 79 2311 2319 10.1016/j.lfs.2006.07.031 1:CAS:528:DC%2BD28XhtFOjur%2FE (Pubitemid 44666069)
- (2006) Life Sciences , vol.79 , Issue.24 , pp. 2311-2319
- Inceoglu, B.¹ Jinks, S.L.² Schmelzer, K.R.³ Waite, T.⁴ Kim, I.H.⁵ Hammock, B.D.⁶

15
- 33845347545
- Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs)
- DOI 10.1016/j.prostaglandins.2006.05.004, PII S1098882306000578, Eicosanoid-Mediated Regulation of Vascular and Renal Function
- B Inceoglu KR Schmelzer C Morisseau SL Jinks BD Hammock 2007 Prostaglandins Other Lipid Mediat 82 42 49 10.1016/j.prostaglandins.2006.05.004 1:CAS:528:DC%2BD28Xht12ktLzL (Pubitemid 44880165)
- (2007) Prostaglandins and Other Lipid Mediators , vol.82 , Issue.1-4 , pp. 42-49
- Inceoglu, B.¹ Schmelzer, K.R.² Morisseau, C.³ Jinks, S.L.⁴ Hammock, B.D.⁵

16
- 0036080081
- 1:CAS:528:DC%2BD38XovFSisQ%3D%3D
- RJ Roman 2002 Physiol Rev 82 131 185 1:CAS:528:DC%2BD38XovFSisQ%3D%3D
- (2002) Physiol Rev , vol.82 , pp. 131-185
- Roman, R.J.¹

17
- 0242720683
- Epoxyeicosatrienoic acids (EETs): Metabolism and biochemical function
- DOI 10.1016/S0163-7827(03)00049-3
- AA Spector X Fang GD Snyder NL Weintraub 2004 Prog Lipid Res 43 55 90 10.1016/S0163-7827(03)00049-3 1:CAS:528:DC%2BD3sXptVemtL4%3D (Pubitemid 37433867)
- (2004) Progress in Lipid Research , vol.43 , Issue.1 , pp. 55-90
- Spector, A.A.¹ Fang, X.² Snyder, G.D.³ Weintraub, N.L.⁴

18
- 0036740840
- 10.1194/jlr.D200018-JLR200 1:CAS:528:DC%2BD38XnsFKhtbk%3D
- JW Newman T Watanabe BD Hammock 2002 J Lipid Res 43 1563 1578 10.1194/jlr.D200018-JLR200 1:CAS:528:DC%2BD38XnsFKhtbk%3D
- (2002) J Lipid Res , vol.43 , pp. 1563-1578
- Newman, J.W.¹ Watanabe, T.² Hammock, B.D.³

19
- 70349627678
- 10.1021/ac901282n 1:CAS:528:DC%2BD1MXhtVKgsL7O
- J Yang K Schmelzer K Georgi BD Hammock 2009 Anal Chem 81 8085 8093 10.1021/ac901282n 1:CAS:528:DC%2BD1MXhtVKgsL7O
- (2009) Anal Chem , vol.81 , pp. 8085-8093
- Yang, J.¹ Schmelzer, K.² Georgi, K.³ Hammock, B.D.⁴

20
- 1642564155
- Restricted access materials and large particle supports for on-line sample preparation: An attractive approach for biological fluids analysis
- DOI 10.1016/j.jchromb.2003.11.043
- S Souverain S Rudaz JL Veuthey 2004 J Chromatogr B 801 141 156 10.1016/j.jchromb.2003.11.043 1:CAS:528:DC%2BD2cXmvFGisA%3D%3D (Pubitemid 38130063)
- (2004) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.801 , Issue.2 , pp. 141-156
- Souverain, S.¹ Rudaz, S.² Veuthey, J.-L.³

21
- 30444448196
- Standard line slopes as a measure of a relative matrix effect in quantitative HPLC-MS bioanalysis
- DOI 10.1016/j.jchromb.2005.11.009, PII S1570023205008305
- BK Matuszewski 2006 J Chromatogr B 830 293 300 10.1016/j.jchromb.2005.11. 009 1:CAS:528:DC%2BD28XksVCktw%3D%3D (Pubitemid 43075465)
- (2006) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.830 , Issue.2 , pp. 293-300
- Matuszewski, B.K.¹

22
- 0037420211
- Optimization of protein precipitation based upon effectiveness of protein removal and ionization effect in liquid chromatography-tandem mass spectrometry
- DOI 10.1016/S1570-0232(02)00914-5, PII S1570023202009145
- C Polson P Sarkar B Incledon V Raguvaran R Grant 2003 J Chromatogr B 785 263 275 10.1016/S1570-0232(02)00914-5 1:CAS:528:DC%2BD3sXmtVaksbc%3D (Pubitemid 36126166)
- (2003) Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences , vol.785 , Issue.2 , pp. 263-275
- Polson, C.¹ Sarkar, P.² Incledon, B.³ Raguvaran, V.⁴ Grant, R.⁵

23
- 34249938957
- Recent advances in high-throughput quantitative bioanalysis by LC-MS/MS
- DOI 10.1016/j.jpba.2007.02.006, PII S0731708507001239, Hyphenated Techniques in Pharmaceutical and Biomedical Analysis 2006
- RN Xu L Fan MJ Rieser TA El-Shourbagy 2007 J Pharm Biomed Anal 44 342 355 10.1016/j.jpba.2007.02.006 1:CAS:528:DC%2BD2sXmtlagur0%3D (Pubitemid 46880094)
- (2007) Journal of Pharmaceutical and Biomedical Analysis , vol.44 , Issue.2 , pp. 342-355
- Xu, R.N.¹ Fan, L.² Rieser, M.J.³ El-Shourbagy, T.A.⁴

24
- 70449641110
- 10.1016/j.aca.2009.10.004 1:CAS:528:DC%2BD1MXhsVCrt7nI
- L Novakova H Vlckova 2009 Anal Chim Acta 656 8 35 10.1016/j.aca.2009.10. 004 1:CAS:528:DC%2BD1MXhsVCrt7nI
- (2009) Anal Chim Acta , vol.656 , pp. 8-35
- Novakova, L.¹ Vlckova, H.²

25
- 33847280369
- Determination of drugs in biological fluids by direct injection of samples for liquid-chromatographic analysis
- DOI 10.1016/j.jbbm.2006.10.001, PII S0165022X06001977, Sample Preparation
- WM Mullett 2007 J Biochem Biophys Methods 70 263 273 10.1016/j.jbbm.2006. 10.001 1:CAS:528:DC%2BD2sXhvVOkurk%3D (Pubitemid 46329140)
- (2007) Journal of Biochemical and Biophysical Methods , vol.70 , Issue.2 , pp. 263-273
- Mullett, W.M.¹

26
- 30344434050
- Turbulent flow chromatography for the reduction of matrix effects in electrospray ionization mass spectrometry-based enzyme assays
- DOI 10.1002/jssc.200500090
- A Liesener U Karst 2005 J Sep Sci 28 1658 1665 10.1002/jssc.200500090 1:CAS:528:DC%2BD2MXhtVyhur7K (Pubitemid 43055009)
- (2005) Journal of Separation Science , vol.28 , Issue.14 , pp. 1658-1665
- Liesener, A.¹ Karst, U.²

27
- 79955561614
- 10.1039/c0ay00714e
- NH Schebb B Inceoglu T Rose K Wagner BD Hammock 2010 Anal Methods 10.1039/c0ay00714e
- (2010) Anal Methods
- Schebb, N.H.¹ Inceoglu, B.² Rose, T.³ Wagner, K.⁴ Hammock, B.D.⁵

28
- 78649564714
- 10.1124/dmd.110.034546 1:CAS:528:DC%2BC3cXhsFGgurjF
- A Baumann W Lohmann T Rose KC Ahn BD Hammock U Karst NH Schebb 2010 Drug Metab Dispos 38 2130 2138 10.1124/dmd.110.034546 1:CAS:528:DC%2BC3cXhsFGgurjF
- (2010) Drug Metab Dispos , vol.38 , pp. 2130-2138
- Baumann, A.¹ Lohmann, W.² Rose, T.³ Ahn, K.C.⁴ Hammock, B.D.⁵ Karst, U.⁶ Schebb, N.H.⁷

29
- 33749251458
- Solid-phase combinatorial approach for the optimization of soluble epoxide hydrolase inhibitors
- DOI 10.1016/j.bmcl.2006.08.078, PII S0960894X06009796
- SH Hwang C Morisseau Z Do BD Hammock 2006 Bioorg Med Chem Lett 16 5773 5777 10.1016/j.bmcl.2006.08.078 1:CAS:528:DC%2BD28XhtVCrt7%2FJ (Pubitemid 44486739)
- (2006) Bioorganic and Medicinal Chemistry Letters , vol.16 , Issue.22 , pp. 5773-5777
- Hwang, S.H.¹ Morisseau, C.² Do, Z.³ Hammock, B.D.⁴

30
- 34548070313
- Orally bioavailable potent soluble epoxide hydrolase inhibitors
- DOI 10.1021/jm070270t
- SH Hwang HJ Tsai JY Liu C Morisseau BD Hammock 2007 J Med Chem 50 3825 3840 10.1021/jm070270t 1:CAS:528:DC%2BD2sXns1Cksbg%3D (Pubitemid 47292046)
- (2007) Journal of Medicinal Chemistry , vol.50 , Issue.16 , pp. 3825-3840
- Sung, H.H.¹ Tsai, H.-J.² Liu, J.-Y.³ Morisseau, C.⁴ Hammock, B.D.⁵

31
- 77957911422
- Rose TE, Morisseau C, Liu JY, Inceoglu B, Jones PD, Sanborn JR, Hammock BD (2010) J Med Chem 53:7067-75
- (2010) J Med Chem , vol.53 , pp. 7067-75
- Rose, T.E.¹ Morisseau, C.² Liu, J.Y.³ Inceoglu, B.⁴ Jones, P.D.⁵ Sanborn, J.R.⁶ Hammock, B.D.⁷

32
- 77953024076
- 10.1016/j.ejps.2010.03.018 1:CAS:528:DC%2BC3cXmsVCru7c%3D
- HJ Tsai SH Hwang C Morisseau J Yang PD Jones T Kasagami IH Kim BD Hammock 2010 Eur J Pharm Sci 40 222 238 10.1016/j.ejps.2010.03.018 1:CAS:528: DC%2BC3cXmsVCru7c%3D
- (2010) Eur J Pharm Sci , vol.40 , pp. 222-238
- Tsai, H.J.¹ Hwang, S.H.² Morisseau, C.³ Yang, J.⁴ Jones, P.D.⁵ Kasagami, T.⁶ Kim, I.H.⁷ Hammock, B.D.⁸

33
- 0027219730
- CDNA cloning and expression of a soluble epoxide hydrolase from human liver
- DOI 10.1006/abbi.1993.1411
- JK Beetham T Tian BD Hammock 1993 Arch Biochem Biophys 305 197 201 10.1006/abbi.1993.1411 1:CAS:528:DyaK3sXlvFynuro%3D (Pubitemid 23242012)
- (1993) Archives of Biochemistry and Biophysics , vol.305 , Issue.1 , pp. 197-201
- Beetham, J.K.¹ Tian, T.² Hammock, B.D.³

34
- 75949096893
- 10.1016/j.chroma.2010.01.008 1:CAS:528:DC%2BC3cXitVKgsro%3D
- F Gritti G Guiochon 2010 J Chromatogr A 1217 1604 1615 10.1016/j.chroma.2010.01.008 1:CAS:528:DC%2BC3cXitVKgsro%3D
- (2010) J Chromatogr A , vol.1217 , pp. 1604-1615
- Gritti, F.¹ Guiochon, G.²

35
- 77952672825
- 10.1016/j.chroma.2010.03.052 1:CAS:528:DC%2BC3cXlvVeitL8%3D
- E Olah S Fekete J Fekete K Ganzler 2010 J Chromatogr A 1217 3642 3653 10.1016/j.chroma.2010.03.052 1:CAS:528:DC%2BC3cXlvVeitL8%3D
- (2010) J Chromatogr A , vol.1217 , pp. 3642-3653
- Olah, E.¹ Fekete, S.² Fekete, J.³ Ganzler, K.⁴

36
- 78149495855
- 10.1016/j.jpba.2010.09.021 1:CAS:528:DC%2BC3cXhsValtrfE
- S Fekete K Ganzler J Fekete 2011 J Pharm Biomed Anal 54 482 490 10.1016/j.jpba.2010.09.021 1:CAS:528:DC%2BC3cXhsValtrfE
- (2011) J Pharm Biomed Anal , vol.54 , pp. 482-490
- Fekete, S.¹ Ganzler, K.² Fekete, J.³

37
- 0028839973
- 10.1006/abbi.1995.1059 1:CAS:528:DyaK2MXjsV2htrg%3D
- DC Zeldin S Wei JR Falck BD Hammock JR Snapper JH Capdevila 1995 Arch Biochem Biophys 316 443 451 10.1006/abbi.1995.1059 1:CAS:528:DyaK2MXjsV2htrg%3D
- (1995) Arch Biochem Biophys , vol.316 , pp. 443-451
- Zeldin, D.C.¹ Wei, S.² Falck, J.R.³ Hammock, B.D.⁴ Snapper, J.R.⁵ Capdevila, J.H.⁶

38
- 45149129386
- Version 5.0 Eli Lilly and Company and NIH Chemical Genomics Center last accessed [24.02.2011]
- Assay Guidance Manual Version 5.0, 2008, Eli Lilly and Company and NIH Chemical Genomics Center. Available online at: http://www.ncgc.nih.gov/guidance/ manual-toc.html (last accessed [24.02.2011])
- (2008) Assay Guidance Manual

39
- 78650051942
- 10.1194/jlr.M006007 1:CAS:528:DC%2BC3cXhsFWitLrF
- C Morisseau B Inceoglu K Schmelzer HJ Tsai SL Jinks CM Hegedus BD Hammock 2010 J Lipid Res 51 3481 3490 10.1194/jlr.M006007 1:CAS:528:DC%2BC3cXhsFWitLrF
- (2010) J Lipid Res , vol.51 , pp. 3481-3490
- Morisseau, C.¹ Inceoglu, B.² Schmelzer, K.³ Tsai, H.J.⁴ Jinks, S.L.⁵ Hegedus, C.M.⁶ Hammock, B.D.⁷

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.