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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 9, 2011, Pages 2650-2654

Design and synthesis of substituted N-(1,3-diphenyl-1H-pyrazol-5-yl) benzamides as positive allosteric modulators of the metabotropic glutamate receptor subtype 5

(5) Zou, Mu Fa a Cao, Jianjing a Rodriguez, Alice L b Jeffrey Conn, P b Newman, Amy Hauck a

a NATIONAL INSTITUTE ON DRUG ABUSE (United States)

b VANDERBILT UNIVERSITY MEDICAL CENTER (United States)

Author keywords

Allosteric modulators; CDPPB; mGluR5; MPEP

Indexed keywords

BENZAMIDE DERIVATIVE; CALCIUM; METABOTROPIC RECEPTOR 5; METABOTROPIC RECEPTOR AGONIST; N (1,3 DIPHENYL 1H PYRAZOL 5 YL)BENZAMIDE DERIVATIVE; UNCLASSIFIED DRUG;

CONFERENCE PAPER; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ALLOSTERIC REGULATION; ANIMALS; BENZAMIDES; CELLS, CULTURED; DRUG DESIGN; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PROTEIN BINDING; PYRAZOLES; RATS; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 79955468360 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2010.12.110 Document Type: Conference Paper

Times cited : (14)

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