Defective deacetylation of histone 4 K12 in human oocytes is associated with advanced maternal age and chromosome misalignment

Human Reproduction

Volumn 26, Issue 5, 2011, Pages 1181-1190

  Van Den Berg, I M ^a   Eleveld, C ^a   Van Der Hoeven, M ^a   Birnie, E ^b   Steegers, E A P ^a   Galjaard, R J ^a   Laven, J S E ^a   Van Doorninck, J H ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

aneuploidy; female meiosis; histone deacetylation; maternal age; misaligned chromosomes

Indexed keywords

ALPHA TUBULIN; HISTONE H4;

ADULT; ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME SEGREGATION; DEACETYLATION; FEMALE; GERMINAL VESICLE; HISTONE ACETYLATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; INTRAUTERINE INSEMINATION; MATERNAL AGE; MEIOSIS; METAPHASE; OOCYTE MATURATION; OOCYTE RETRIEVAL;

EID: 79955459207     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/der030     Document Type: Article

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