Susceptible chiasmate configurations of chromosome 21 predispose to non- disjunction in both maternal meiosis I and meiosis II

Nature Genetics

Volumn 14, Issue 4, 1996, Pages 400-405

  Lamb, Neil E ^a   Freeman, Sallie B ^a   Savage Austin, Amanda ^a   Pettay, Dorothy ^a   Taft, Lisa ^a   Hersey, Jane ^a   Gu, Yuanchao ^a   Shen, Joe ^b   Saker, Denise ^b   May, Kristen M ^a   Avramopoulos, Dimitris ^c   Petersen, Michael B ^c,d   Hallberg, Anni ^d   Mikkelsen, Margareta ^d   Hassold, Terry J ^b   Sherman, Stephanie L ^a,b  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Institute of Child Health   (Greece)

^d JOHN F KENNEDY INSTITUTE   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; CHROMOSOME CHIASM; CONTROLLED STUDY; FEMALE; GENETIC RECOMBINATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; MEIOSIS; NEWBORN; NONDISJUNCTION; PRIORITY JOURNAL; TRISOMY 21;

ADULT; CHROMOSOMES, HUMAN, PAIR 21; DOWN SYNDROME; EMBRYO; FEMALE; FETUS; HUMANS; MALE; MATERNAL AGE; MEIOSIS; MODELS, GENETIC; NONDISJUNCTION, GENETIC; RECOMBINATION, GENETIC;

EID: 10544226872     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1296-400     Document Type: Article

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