Influence of maternal age on meiotic spindle assembly in oocytes from naturally cycling women

Human Reproduction

Volumn 11, Issue 10, 1996, Pages 2217-2222

  Battaglia, D E ^a   Goodwin, P ^b   Klein, N A ^a   Soules, M R ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

Author keywords

Ageing; Aneuploidy; Human oocyte; Meiosis

Indexed keywords

TUBULIN;

ADULT; AGING; ANEUPLOIDY; ARTICLE; CHROMOSOME; FEMALE; HUMAN; MATERNAL AGE; MEIOSIS; METAPHASE; MICROTUBULE; NORMAL HUMAN; OOCYTE;

EID: 0029823305     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.humrep.a019080     Document Type: Article

References (36)

1. Albertini, D.F. (1987) Cytoplasmic reorganization during the resumption of meiosis in cultured preovulatory rat oocytes. Dev. Biol., 120, 121-131.
2. Albertini, D.F. (1992) Regulation of meiotic maturation in the mammalian oocyte - interplay between exogenous cues and the microtubule cytoskeleton. Bioessays, 14, 97-103.
3. Angell, R.R., Xian, J., Keith, J., Ledger, W. and Baird, D.T. (1994) First meiotic division abnormalities in human oocytes: mechanism of trisomy formation. Cytogenet. Cell Genet., 65, 194-202.
4. Battaglia, D., Klein, N.A. and Soules, M.R. (1996) Changes in centrosomal domains during meiotic maturation in the human oocyte. Mol. Hum. Reprod., 2, in press.
5. Brook, J.D., Gosden, R.G. and Chandley, A.C. (1984) Maternal ageing and aneuploid embryos - evidence from the mouse that biological and not chronological age is the important influence. Hum. Genet., 66, 41-45.
6. Butcher, R.L. and Fugo, N.W. (1967) Overripeness and the mammalian ova. II. Delayed ovulation and chromosome anomalies. Fertil. Steril., 18, 297-302.
7. Egozcue, J. (1987) Cellular aspects of in vitro fertilization. Ultrastructural and cytogenetic studies of human gametes and zygotes. Rev. Biol. Cell., 13, 1-104.
8. Eichenlaub-Ritter, U. and Boll, I. (1989) Nocodazole sensitivity, age-related aneuploidy, and alterations in the cell cycle during maturation of mouse oocytes. Cytogenet. Cell Genet., 52, 170-176.
9. Eichenlaub-Ritter, U., Chandley, A.C. and Gosden, R.G. (1988a) The CBA mouse as a model for age-related aneuploidy in man: studies of oocyte maturation, spindle formation and chromosome alignment during meiosis. Chromosoma, 96, 220-226.
10. Eichenlaub-Ritter, U., Stahl, A. and Luciani, J.M. (1988b) The microtubular cytoskeleton and chromosomes of unfertilized human oocytes aged in vitro. Hum. Genet., 80, 259-264.
11. Ford, J.H. and Lester, P. (1982) Factors affecting the displacement of human chromosomes from the metaphase plate. Cytogenet. Cell Genet., 33, 327-332.
12. Gianfortoni, J.G. and Gulyas, B.J. (1985) The effects of short-term incubation (aging) of mouse oocytes on in vitro fertilization, zona solubility, and embryonic development. Gamete Res., 11, 59-68.
13. Gras, L., McBain, J., Trounson, A. and Kola, I. (1992) The incidence of chromosomal aneuploidy in stimulated and unstimulated (natural) uninseminated human oocytes. Hum. Reprod., 7, 1396-1401.
14. Harman, D. (1956) Aging: a theory based on free radical and radiation chemistry. J. Gerontol., 11, 298-300.
15. Hollander, D. and Breen, J.L. (1991) Pregnancy in the older gravida: how old is old? Obstet. Gynecol. Surv., 45, 106-112.
16. Hook, E. (1981) Rates of chromosomal abnormalities at different maternal ages. Obstet. Gynecol., 58, 282.
17. Hunt, P., LeMaire, R., Embury, P., Sheean, L. and Mroz, K. (1995) Analysis of chromosome behavior in intact mammalian oocytes: monitoring the segregation of a univalent chromosome during female meiosis. Hum. Mol. Genet., 4, 2007-2012.
18. Klein, N.A., Battaglia, D.E., Miller, P.B. et al. (1996a) Ovarian follicular development and the follicular fluid hormones and growth factors in normal women of advanced reproductive age. J. Clin. Endocrinol. Metab., 81, 1946-1951.
19. Klein, N.A., Illingworth, P.J., Groome, N.P. et al. (1996b) Decreased inhibin B secretion is associated with the monotropic FSH rise in older, ovulatory women: a study of serum and follicular fluid levels of dimeric inhibin A and B in spontaneous menstrual cycles. J. Clin. Endocrinol. Metab., 81, 2742-2745.
20. Lanman, J.T. (1968) Delays during reproduction and their effects on the embryo and fetus. N. Engl. J. Med., 278, 1047-1054.
21. Longo, F.J. (1981) Changes in the zonae pellucidae and plasmalemmae of aging mouse eggs. Biol. Reprod., 25, 399-411.
22. Mattson, B.A. and Albertini, D.F. (1990) Oogenesis: chromatin and microtubule dynamics during meiotic prophase. Mol. Reprod. Dev., 25, 374-383.
23. Meldrum, D.R. (1993) Female reproductive aging - ovarian and uterine factors. Fertil. Steril., 59, 1-5.
24. Messinger, S.M. and Albertini, D.F. (1991) Centrosome and microtubule dynamics during meiotic progression in the mouse oocyte. J. Cell Sci., 100, 289-298.
25. Mikamo, K. (1968) Mechanism of non-disjunction of meiotic chromosomes and of degeneration of maturation spindles in eggs affected by intrafollicular overripeness. Experientia, 24, 75-78.
26. National Center for Health Statistics (1988) Advance report of final natality statistics, 1986. Monthly Vital Stat. Rep., 37, 1-7.
27. National Center for Health Statistics (1989) Advance report of final marriage statistics, 1986. Monthly Vital Stat. Rep., 38, 1-6.
28. Navot, D., Bergh, P.A., Williams, M.A. et al. (1991) Poor oocyte quality rather than implantation failure as a cause of age-related decline in female infertility. Lancet, 337, 1375-1377.
29. Nogues, C., Ponsa, M., Vidal, F., Boada, M. and Egozcue, J. (1988) Effects of aging on the zona pellucida surface of mouse oocytes. J. In Vitro Fertil. Embryo Transf., 5, 225-229.
30. Pickering, S.J., Johnson, M.H., Braude, P.R. and Houliston, E. (1988) Cytoskeletal organization in fresh, aged and spontaneously activated human oocytes. Hum. Reprod., 3, 978-989.
31. Pickering, S.J., Braude, P.R., Johnson, M.H., Cant, A. and Currie, J. (1990) Transient cooling to room temperature can cause irreversible disruption of the meiotic spindle in the human oocyte. Fertil. Steril., 54, 102-108.
32. Sauer, M.V., Paulson, R.J. and Lobo, R.A. (1990) A preliminary report on oocyte donation extending reproductive potential to women over 40. N. Engl. J. Med., 323, 1157-1160.
33. Szollosi, D. (1975) Mammalian eggs aging in the Fallopian tubes. In Blandau, R.J. (ed.), Aging Gametes. Their Biology and Pathology, S. Karger, New York, pp. 98-121.
34. Tarin, J.J. (1995) Aetiology of age-associated aneuploidy: a mechanism based on the 'free radical theory of ageing'. Hum. Reprod., 10, 1563-1565.
35. Van Blerkom, J., Davis, P.W. and Lee, J. (1995) ATP content of human oocytes and developmental potential and outcome after in vitro fertilization and embryo transfer. Hum. Reprod., 10, 415-424.
36. Wickramasinghe, D., Ebert, K.M. and Albertini, D.F. (1991) Meiotic competence acquisition is associated with the appearance of M-phase characteristics in growing mouse oocytes. Dev. Biol., 143, 162-172.